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用XML与jAVA创建程序生成器

Impact of colorectal cancer screening participation in remote northern Canada:A retrospective cohort study

丛书名：科海电脑技术丛书

2002年

作者：（美）j.craig Cleaveland 胡俊刘吉强译

本书将XML、jAVA、jSP及程序生成器等概念与方法结合起来，通过域分析的思路、方法、过程以及一些易于理解的示例，来介绍使用XML与jAVA创建程序生成器的方法与过程。

ISBN: (纸本)703010434X

关键词：可扩充语言计算机网络 jAVA语言程序设计

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World journal of Gastroenterology 2020年第48期26卷 7652-7663页

作者： Heather A Smith Andrew D Scarffe Nicole Brunet Cait Champion Kami Kandola Alisha Tessier Robin Boushey craig Kuziemsky Department of Surgery University of OttawaOttawa K1Y4E9OntarioCanada Telfer School of Management University of OttawaOttawa K1N6N5OntarioCanada Faculty of Medicine University of OttawaOttawa K1Y4E9OntarioCanada Department of Surgery Northern Ontario School of MedicineSudbury P3E2C6OntarioCanada Department of Health and Social Services Government of the Northwest TerritoriesYellowknife X1A1P5Northwest TerritoriesCanada Department of Surgery Stanton Territorial Health AuthorityYellowknife X1A0H1Northwest TerritoriesCanada Division of General Surgery University of OttawaOttawa K1H 8L6OntarioCanada Office of Research Services MacEwan UniversityEdmonton T5J4S2AlbertaCanada

BACKGROUND Screening provides earlier colorectal cancer(CRC)detection and improves *** remains poorly understood if these benefits are realized with screening guidelines in remote northern populations of Canada where CRC rates are nearly twice the national average and access to colonoscopy is *** To evaluate the participation and impact of CRC screening guidelines in a remote northern *** This retrospective cohort study included residents of the Northwest Territories,a northern region of Canada,age 50-74 who underwent CRC screening by a fecal immunohistochemical test(FIT)between january 1,2014 to March 30,*** assess impact,individuals with a screen-detected CRC were compared to clinically-detected CRC cases for stage and location of CRC between *** assess participation,we conducted subgroup analyses of FIT positive individuals exploring the relationships between signs and symptoms of CRC at the time of screening,wait-times for colonoscopy,and screening *** sample Welch t-test was used for normally distributed continuous variables,Mann-Whitney-Wilcoxon Tests for data without normal distribution,and Chi-square goodness of fit test for categorical variables.A P value of<0.05 was considered to be statistically *** 6817 fecal tests were completed,meaning an annual average screening rate of 25.04%,843(12.37%)were positive,629 individuals underwent a follow-up colonoscopy,of which,24.48%had advanced neoplasia(AN),5.41%had *** were no significant differences in stage,pathology,or location between screen-detected cancers and clinically-detected *** assessing participation and screening outcomes,we observed 49.51%of individuals referred for colonoscopy after FIT were ineligible for CRC screening,most often due to signs and symptoms of *** were more likely to have AN if they had signs and symptoms of cancer at the time of screening,waited over 180 d for colonoscopy,or were indigenous[

关键词： Gastroenterology Rural health services Public health Colorectal neoplasms Early detection of cancer Northwest Territories

Radiation-induced oral mucositis hamster model using a linear accelerator enhances clinical relevance of preclinical studies for treatment strategy investigation

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Animal Models and Experimental Medicine 2021年第1期4卷 47-53页

作者： Carolyn T.jordan Emily M.Bradford Dennis C.Cheek Mahesh Kudrimoti craig S.Miller Molly H.Smith j.Zach Hilt Thomas D.Dziubla Department of Chemical and Materials Engineering University of KentuckyLexingtonKYUSA Department of Internal Medicine University of KentuckyLexingtonKYUSA Department of Radiation Medicine University of KentuckyLexingtonKYUSA Department of Oral Health Practice University of KentuckyLexingtonKYUSA Department of Oral and Maxillofacial Pathology University of KentuckyLexingtonKYUSA

Translational animal models for oral mucositis(OM)are necessary to simulate and assess the bioclinical effects and response in *** models should simulate high levels of radiation exposure that leads to oxidative stress and inflammatoryinitiated tissue *** models have been extensively studied to observe pathological effects of radiation exposure and help in the development of effective *** successfully evaluate the potential for treatment regimens with consistency and relevance,a radiation-induced OM hamster model was developed using a clinical linear accelerator utilized by cancer patients *** dose exposure to the isolated,everted cheek pouch of a hamster,as well as the progression of injury,proinflammatory marker,histological,and elasticity analyses of the buccal pouch were conducted to verify replicability and reproducibility of the injury *** findings from this model demonstrated its ability to consistently induce injury and resolution over 28 days using an acute dose of 60 *** model was developed to enhance clinical relevance when evaluating potential efficacious treatments and can now be utilized in efficacy studies to better evaluate developed therapeutics in a preclinical model that is easy to translate to clinical studies..

关键词： animal models radiotherapy stomatitis

Paleoproterozoic juvenile magmatism within the northeastern sector of the Sao Francisco paleocontinent:Insights from the shoshonitic high Ba-Sr Montezuma granitoids

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Geoscience Frontiers 2020年第5期11卷 1821-1840页

作者： Samuel Moreira Bersan Alice Fernanda de Oliveira Costa Andre Danderfer Francisco Roberio de Abreu Cristiano Lana Glaucia Queiroga craig Storey Hugo Moreira Universidade Federal de Ouro Preto Programa de Pos-graduacaoDepartamento de GeologiaCampus Morro do CruzeiroOuro PretoMGCEP 35400-000Brazil Universidade Federal de Ouro Preto Departamento de GeologiaCampus Morro do CruzeiroOuro PretoMGCEP 35400-000Brazil Sustain Geologia Ltda Teresa M.Valadares 503/502Belo HorizonteMGCEP 30575-160Brazil University of Portsmouth School of Earth and Environmental SciencesBurnaby BuildingBurnaby RoadPortsmouthPO13QLUK

New,integrated petrographic,mineral chemistry,whole rock geochemical,zircon and titanite UPb geochronology,and zircon Hf isotopic data from the Montezuma granitoids,as well as new geochemical results for its host rocks represented by the Corrego Tingui Complex,provides new insights into the late-to post-collisional evolution of the northeastern Sao Francisco paleocontinent.U-Pb zircon dates from the Montezuma granitoids spread along the Concordia between ca.2.2 Ga to 1.8 Ga and comprise distinct *** I have crystallization ages between ca.2.15 Ga and 2.05 Ga and are interpreted as inherited *** II zircon dates vary from 2.04 Ga to1.9 Ga and corresponds to the crystallization of the Montezuma granitoids,which were constrained at ca.2.03 Ga by the titanite U-Pb *** age zoning is common within the ca.1.8 Ga Group III zircon ages,being related to fluid isotopic re-setting during the Espinhaco rifiting ***εHf(t)analysis show dominantly positive values for both Group I(-4 to+9)andⅡ(-3 to+8)zircons and TDM2 model ages of 2.7-2.1 Ga and 2.5-1.95 Ga,***,the Montezuma granitoids are weakly peraluminous to metaluminous magnesian granitoids,enriched in LILES and LREE,with high to moderate Mg#and depleted in some of the *** lithochemical signature,added to the juvenile signature of both inherited and crystallized zircons,allowed its classification as a shoshonitic high Ba-Sr granitoid related to a late-to post-collisional lithosphere delamination followed by asthenospheric *** this scenario,the partial melting of the lithospheric mantle interacted with the roots of an accreted juvenile intra-oceanic arc,being these hybrid magma interpreted as the source of the Montezuma *** Corrego Tingui Complex host rocks are akin to a syn-to late-collisional volcanic arc granitoids originated from the partial melting of ancient crustal *** results presented in this study have revealed the occurrence of j

关键词： Zircon U–Pb-Hf Titanite U–Pb High Ba–Sr Late-to post-collisional Sao Francisco paleocontinent

An acute naproxen dose does not affect core temperature or Interleukin-6 during cycling in a hot environment

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Sports Medicine and Health Science 2021年第4期3卷 243-251页

作者： Dawn M.Emerson Stephen CL.Chen Toni M.Torres-McGehee craig E.Pfeifer Charles C.Emerson j.Mark Davis Department of Physical Therapy Rehabilitation Scienceand Athletic TrainingSchool of Health ProfessionsUniversity of Kansas Medical Center3901 Rainbow BlvdMS 2002Kansas CityKansas66160USA. Division of Exercise and Sport Science Bob Jones University1700 Wade Hampton BlvdGreenvilleSouth Carolina29614USA. Department of Exercise Science Arnold School of Public HealthUniversity of South Carolina921 Assembly StreetColumbiaSC29208USA Applied Sport and Exercise Sciences The ParkUniversity of GloucestershireCheltenham GL502RHUnited Kingdom. Department of Athletics 5100 Rockhill Rd SRC 201University of Missouri-Kansas CityKansas CityMissouri64110USA.

Non-steroidal anti-inflammatory drugs’anti-pyretic and anti-inflammatory effects has led some individuals to theorize these medications may blunt core body temperature(Tc)increases during *** utilized a double-blind,randomized,and counterbalanced cross-over design to examine the effects of a 24-h naproxen dose(3–220 mg naproxen pills)and placebo(0 mg naproxen)on Tc and plasma interleukin-6(IL-6)concentrations during cycling in a hot or ambient ***(n=11;6 male,5 female;age=27.8±6.5 years,weight=79.1±17.9 kg,height=177±9.5 cm)completed 4 conditions:1)placebo and ambient(Control);2)placebo and heat(Heat);3)naproxen and ambient(Npx);and 4)naproxen and heat(NpxHeat).Dependent measures were taken before,during,and immediately after 90 min of cycling and then 3 h after ***,Tc significantly increased pre-(37.1±0.4℃)to post-cycling(38.2±0.3℃,F_(1.7,67.3)=150.5,p<0.001)and decreased during rest(37.0±0.3℃,F_(2.0,81.5)=201.6,p<0.001).Rate of change or maximum Tc were not significantly different between ***-6 increased pre-(0.54±0.06 pg/ml)to post-exercise(2.46±0.28 pg/ml,p<0.001)and remained significantly higher than pre-at 3 h post-(1.17±0.14 pg/ml,95%CI=-1.01 to-0.23,p=0.001).No significant IL-6 differences occurred between conditions.A 24-h,over-the-counter naproxen dose did not significantly affect Tc or IL-6 among males and females cycling in hot or ambient environments.

关键词： Cytokine Exertional heat illness NSAIDs Thermoregulation Exercise

Subnanometer localization accuracy in widefield optical microscopy

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Light(Science & Applications) 2018年第1期7卷 740-754页

作者： craig R.Copeland jon Geist craig D.McGray Vladimir A.Aksyuk j.Alexander Liddle B.Robert Ilic Samuel M.Stavis Center for Nanoscale Science and Technology National Institute of Standards and TechnologyGaithersburgMD 20899USA Maryland NanoCenter University of MarylandCollege ParkMD 20742USA Engineering Physics Division National Institute of Standards and TechnologyGaithersburgMD 20899USA

The common assumption that precision is the limit of accuracy in localization microscopy and the typical absence of comprehensive calibration of optical microscopes lead to a widespread issue—overconfidence in measurement results with nanoscale statistical uncertainties that can be invalid due to microscale systematic *** this article,we report a comprehensive solution to this underappreciated *** develop arrays of subresolution apertures into the first reference materials that enable localization errors approaching the atomic scale across a submillimeter *** present novel methods for calibrating our microscope system using aperture arrays and develop aberration corrections that reach the precision limit of our reference *** correct and register localization data from multiple colors and test different sources of light emission with equal accuracy,indicating the general applicability of our reference materials and calibration *** a first application of our new measurement capability,we introduce the concept of critical-dimension localization microscopy,facilitating tests of nanofabrication processes and quality control of aperture *** a second application,we apply these stable reference materials to answer open questions about the apparent instability of fluorescent nanoparticles that commonly serve as fiducial *** study establishes a foundation for subnanometer localization accuracy in widefield optical microscopy.

关键词： optical limit field

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中国高粱抗高粱霜霉病鉴定研究

辽宁农业科学 1989年第6期 17-21页

作者：卢庆善 j.craig K.F.Schertz 辽宁省农业科学院高粱研究所美国农业部农业研究站和得克萨斯农业和机械大学植物病理和微生物学系美国农业部农业研究站和得克萨斯农业和机械大学作物土壤学系

高粱霜霉病是由高粱霜霉菌[Peronosclerospora sorghi(Weston and Uppal)Shaw]引起的一种真菌病害,能为害高粱、玉米、珍珠粟等农作物.它最早发生在亚洲、非洲的一些国家.在1949年汇总的植物病害分布图上(C. M. I. Distribution Map of ... 详细信息

高粱霜霉病是由高粱霜霉菌[Peronosclerospora sorghi(Weston and Uppal)Shaw]引起的一种真菌病害,能为害高粱、玉米、珍珠粟等农作物.它最早发生在亚洲、非洲的一些国家.在1949年汇总的植物病害分布图上(C. M. I. Distribution Map of Plant Diseases),还有中国和意大利.但后来没有证实.1956年,在美洲巴拿马饲料高梁上发现高粱霜霉病.不久,此病在美洲的一些国家相继传播开来.1961年,在美国得克萨斯州最先发现高梁霜霉病.1967年以后,高粱霜霉病成为美国第一个主要的作物流行病.70年代初期。

关键词：高粱霜霉病品种抗病性

Elevated Linoleic Acid (A Pro-Inflammatory PUFA) and Liver Injury in a Treatment Naive HIV-HCV Co-Infected Alcohol Dependent Patient

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journal of Biosciences and Medicines 2016年第7期4卷 23-27页

作者： Vatsalya Vatsalya Shirish S. Barve craig j. McClain Vijay A. Ramchandani Division of Gastroenterology Hepatology and Nutrition Department of Medicine University of Louisville School of Medicine Louisville USA Section on Human Psychopharmacology LCTS/DICBR/NIAAA at National Institutes of Health Bethesda USA Department of Pharmacology and Toxicology University of Louisville School of Medicine Louisville USA Robley Rex VA Medical Center Louisville USA

HIV and HCV co-infection is a unique disease condition, and medical management of such condition is difficult due to severity and systemic complications. Added with heavy alcohol drinking, risk of liver injury increases due to several pro-inflammatory responses that subsequently get involved with alcohol metabolism. Elevated levels of fatty acids have been reported both in viral infections as well as alcoholic liver disease though such investigations have not addressed the adverse event with dual viral infection of HIV and HCV along with heavy drinking. This case report of a patient with excessive alcohol drinking and first time diagnosis of HIV and HCV dual infection, elaborating concurrent alteration in Linoleic Acid (LA) levels and pro-inflammatory shift in ω-6/ω-3 ratio along with the elevations in liver injury markers. Elevated LA has been recently studied extensively for its role in alcoholic liver disease;and in the present case, we also found it to be clinically relevant to liver injury.

关键词： Alcohol Fatty Acids HCV HIV Liver Injury

Synthesis and Characterization of Gadolinium Oxide-Hematite Magnetic Ceramic Nanostructures

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journal of Minerals and Materials Characterization and Engineering 2023年第1期11卷 1-15页

作者： Sarah Glasser Andrew j. craig Felicia Tolea Mihaela Sofronie jennifer A. Aitken Monica Sorescu Department of Physics Duquesne University Fisher Hall Pittsburgh PA USA Department of Chemistry and Biochemistry Duquesne University Mellon Hall Pittsburgh PA USA National Institute of Materials Physics Bucharest-Magurele Romania

Mixed-oxide nanostructures of the type xGd2O3-(1-x)α-Fe2O3 (x=0.1, 0.3, 0.5 and 0.7) were synthesized by mechanochemical activation for ball milling times of 0, 2, 4, 8 and 12 hours. The systems were subsequently analyzed by Mӧssbauer spectroscopy, X-ray powder diffraction (XRPD), magnetic measurements and optical diffuse reflectance spectroscopy. The magnetic hyperfine field was studied as function of ball milling time for all sextets involved and found to be consistent with the formation of a limited solid solution in the systems investigated. The end-product was the gadolinium perovskite, represented by a doublet whose abundance was derived as function of the milling time. The XRPD patterns recorded for the equimolar composition were dominated by the diffraction peaks of GdFeO3 after 12 hours of milling. The hysteresis loops were recorded at 300 and 5 K in an applied magnetic field of 5 T and were interpreted as a superposition of paramagnetic behavior of gadolinium oxide and weak ferromagnetic behavior of hematite and gadolinium perovskite. The Morin transition of hematite was inferred from zero-field-cooling-field-cooling (ZFC-FC) curves measured with a magnetic field of 200 Oe in the 5-300 K temperature range and was found to depend on the ball milling time. Optical diffuse reflectance spectra showed that the compounds were semiconductors with an optical band gap of 2.1 eV.

关键词： Gadolinium Oxide Hematite Mӧssbauer Spectroscopy Magnetic Properties Optical Properties