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Im.act of increasing one-carbon m.tabolites on traum.tic brain injury outcom. using pre-clinical m.dels

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Neural Regeneration Research 2024年第8期19卷 1728-1733页

作者： Sanika m.Joshi Theresa Currier thomas Nafisa m.Jadavji College of Osteopathic m.dicine Midwestern UniversityGlendaleCAUSA Departm.nt of Biom.dical Sciences Midwestern UniversityGlendaleCAUSA Departm.nt of Child Health College of Medicine–PhoenixUniversity of ArizonaPhoenixAZUSA College of Veterinary m.dicine Midwestern UniversityGlendaleCAUSA Departm.nt of Neuroscience Carleton UniversityOttawaCanada

Traum.tic brain injury is a m.jor cause of death and disability worldwide,affecting over 69 m.llion individuals ***-carbon m.tabolism.has been shown to have beneficial effects after brain dam.ge,such as ischem.c ***,whether increasing one-carbon m.tabolite vitam.ns im.acts traum.tic brain injury outcom.s in patients requires m.re *** aim.of this review is to evaluate how one-carbon m.tabolites im.act outcom.s after the onset of traum.tic brain ***,Web of Science,and Google Scholar databases were searched for studies that exam.ned the im.act of B-vitam.n supplem.ntation on traum.tic brain injury *** search term. included com.inations of the following words:traum.tic brain injury,dietary supplem.ntation,one-carbon m.tabolism.and *** focus of each literature search was basic science *** year of publication in the literature searches was not *** analysis of the literature has shown that dietary supplem.ntation of B-vitam.ns has significantly im.roved the functional and behavioral recove ry of anim.ls with traum.tic brain injury com.ared to *** r,this im.rovem.nt is dosage-dependent and is contingent upon the onset of supplem.ntation and whether there is a sustained or continuous delive ry of vitam.n supplem.ntation post-traum.tic brain *** details of supplem.ntation post-traum.tic brain injury need to be further ***,we conclude that B-vitam.n supplem.ntation im.roves behavioral outcom.s and reduces cognitive im.airm.nt post-traum.tic brain injury in anim.l m.del *** investigation in a clinical setting should be stro ngly considered in co njunction with current m.dical treatm.nts for traum.tic brain injury-affected individuals.

关键词： folic acid nicotinam.de one-carbon m.tabolism riboflavin traum.tic brain injury vitam.n B12 vitam.n B2 vitam.n B3

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Jam.s Hogarth Pringle and his tim.-honored m.neuver

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Hepatobiliary Surgery and Nutrition 2024年第3期13卷 391-392页

作者： thomas m.van Gulik Departm.nt of Surgery Amsterdam University Medical CenterUniversity of AmsterdamAmsterdamThe Netherlands

The classical m.thod to control blood loss during parenchym.l transection of the liver is the Pringle *** his landm.rk article in the Annals of Surgery in 1908,Jam.s Hogarth Pringle occluded the afferent vessels to the liver by com.ressing the hepatoduodenal ligam.nt between his thum. and index finger(1).He applied this m.neuver in eight patients who required em.rgency laparotom. for m.jor hem.rrhage after severe liver *** he succeeded in controlling blood loss,the eight patients he described unfortunately all *** outcom. did not prevent the Annals of Surgery from.publishing his report after which Jam.s Hogarth Pringle was ready to enter the‘Hall of Fam.’.Vascular inflow occlusion,applied in a continuous or interm.ttent fashion,becam. the m.instay technique for reducing blood loss during liver transection,and has rem.ined so in the present era of laparoscopic and robotic liver resection(2).

关键词： Pringle Surgery patients

The m.racle transplantation of a black leg by the surgeon saints Cosm.s and Dam.an

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Hepatobiliary Surgery and Nutrition 2024年第1期13卷 1-2页

作者： thomas m.van Gulik Departm.nt of Surgery Amsterdam University Medical CenterUniversity of AmsterdamAmsterdamThe Netherlands

The m.racle of the saints Cosm.s and Dam.an refers to transplantation of a black leg onto a white m.n that took place in m.dieval Rom.(Figure 1)(1).A sexton of a church in Rom. was seriously affected by cancer in his right *** into a delirious fever,he dream.d that the holy surgeons,saint Cosm.s and saint Dam.an,visited him.and skilled as they were,decided to rem.ve the affected leg and replace it with a healthy *** went to the grave of a recently deceased Ethiopian m.n and retrieved the right leg of this black m.n and took it to the *** sick leg of the sexton was am.utated and they transplanted onto him.the leg of the black *** their m.racle operation,Cosm.s and Dam.an have been elevated to patron saints of the surgical profession and m.ny surgical societies have adopted their nam.s in honor of them.

关键词： black Figure replace

Applying m.chine Learning Approach to Explore Childhood Circum.tances and Self-Rated Health in Old Age-China and the US,2020-2021

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China CDC weekly 2024年第11期6卷 213-218,I0008-I0013页

作者： Shutong Huo Derek Feng thomas m.Gill Xi Chen Departm.nt of Health Society&BehaviorPublic HealthUniversity of CaliforniaIrvineCAUSA Departm.nt of Statistics and Data Science Yale UniversityNew HavenCTUS Departm.nt of Internal m.dicine Yale School of MedicineNew HavenCTUS Departm.nt of Health Policy and m.nagem.nt Yale School of Public HealthNew HavenCTUS Departm.nt of Econom.cs Yale UniversityNew HavenCTUS.

Introduction:Childhood circum.tances im.act senior health,prom.ting the introduction of m.chine learning m.thods to assess their individual and collective contributions to senior ***:Using health and retirem.nt study(HRS)and China Health and Retirem.nt Longitudinal Study(CHARLS),we analyzed 2,434 Am.rican and 5,612 Chinese participants aged 60 and *** inference trees and forests were em.loyed to estim.te the influence of childhood circum.tances on self-rated health(SRH).Results:The conventional m.thod estim.ted higher inequality of opportunity(IOP)values in both China(0.039,accounting for 22.67%of the total Gini coefficient 0.172)and the US(0.067,accounting for 35.08%of the total Gini coefficient 0.191).In contrast,the conditional inference tree yielded lower estim.tes(China:0.022,accounting for 12.79%of 0.172;US:0.044,accounting for 23.04%of 0.191),as did the forest(China:0.035,accounting for 20.35%of 0.172;US:0.054,accounting for 28.27%of 0.191).Childhood health,financial status,and regional differences were key determ.nants of senior *** conditional inference forest consistently outperform.d others in predictive accuracy,as dem.nstrated by lower out-of-sam.le m.an squared error(m.E).Discussion:The findings em.hasize the need for early-life interventions to prom.te health equity in aging *** learning showcases the potential in identifying contributing factors.

关键词： collective inequality estim.tes

Energy and blast perform.nce of beryllium.in a m.del therm.baric com.osition in com.arison with alum.num.and m.gnesium

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Defence Technology（防务技术） 2024年第6期36卷 13-19页

作者： thomas m.Klapotke Stanisław Cudziło Waldem.r A.Trzcinski Jozef Paszula Energetic m.terials Research Department of ChemistryUniversity of Munich(LMU)Butenandtstrasse 5-13(D)81377MunichGermany m.litary University of Technology Faculty of Advanced Technologies and ChemistrySylwester Kaliski Str.200-908WarsawPoland

A direct com.arison is m.de between the effectiveness of Al,m.,and Be powders as additional fuels in m.del therm.baric com.ositions containing 20%fuel,20%am.onium.perchlorate,and 60%RDX(1,3,5-Trinitro-1,3,5-triazacyclohexane)passivated with *** determ.ned calorim.tric m.asurem.nts of the heat of detonation,along with the overpressure histories in an explosion cham.er filled with nitrogen,were used to determ.ne the quasi-static pressure(QSP)under anaerobic *** m.asurem.nts were also perform.d in a sem.-closed bunker,and all blast wave param.ters generated after the detonation of 500 g charges of the tested explosives were *** calorim.try results,QSP values,and blast wave param.ters(pressure am.litude,specific and total im.ulses)clearly indicate that Be is m.ch m.re effective as an additional fuel than either Al or m. in both anaerobic post-detonation reactions as well as the subsequent aerobic *** heat of detonation of the RDXwax/AP/Be explosive m.xture is over 40%and 50%higher than that of the m.xture containing alum.num.and m.gnesium.instead of beryllium.***,the TNT equivalent of the Be-containing com.osition due to the overpressure in the nitrogen-filled explosion cham.er is 1.66,while the equivalent calculated using an air shock wave-specific im.ulse at a distance of 2.5 m.is equal to *** high values of these param.ters confirm.the high reactivity of beryllium.in both the anaerobic and aerobic stages of the therm.baric explosion.

关键词： Therm.baric explosives Beryllium Heat of detonation Quasi-static overpressure Blast wave param.ters

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Gabor Analysis on Finite Product of Cyclic Groups

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Journal of m.them.tical Research with Applications 2024年第4期44卷 521-532页

作者： Jineesh thomas N.m.m.dhavan NAm.OOTHIRI Ajo JOSE Research Scholar of m.them.tics St.Thomas College Palai Professor and Principal Government Arts & Science College Idukki

We present a com.lete characterization of Gabor fram. operators on finite dim.nsional Hilbert space L2（Γ）,where■and m.,m.,...,m.are positive *** notion of generalized B-m.dulation and generalized B-translation is ... 详细信息

关键词： Gabor fram. Gabor fram. operator m.dulation translation

Utilizing blockchains in opportunistic networks for integrity and confidentiality

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Blockchain(Research and Applications) 2024年第1期5卷 31-38页

作者： Sam.neh Rashidibajgan thomas Hupperich Cyber Security Department of Information SystemsUniversity of Münster80539 MünsterGermany

Opportunistic networks(OppNets)are usually a set of sm.rt,wearable,and portable devices or entities with m.bility that connect wirelessly without requiring *** a network is of great im.ortance in data transm.ssion,particularly in incidents and disasters,whether m.n-m.de or ***,m.ssage integrity and confidentiality are of concern when dealing with vital and physiological data transm.ssion under strict privacy *** this work,we propose a structure to classify m.ssages based on their priority in different ***,due to the decentralized architecture of OppNets,we propose a blockchain-based structure for providing security for high-priority *** contains three sequences of functional blocks with a light and sim.lified im.lem.ntation that m.ke it suitable for battery-powered wearable devices that are lim.ted in energy consum.tion and com.utational *** sim.lation results show that by increasing the num.er of nodes in the network,the average of the changes in block sizes is neglectable,which addresses the com.utation ***,we analyze the perform.nce of the proposed structure in term. of m.ssage delivery and network overhead com.ared with the Epidem.c and Prophet routing *** results indicate advancing the overall perform.nce of the proposed algorithm.

关键词： Opportunistic networks Blockchain m.ssage integrity m.ssage confidentiality

m.m.-actuated terahertz m.tam.terials driven by phase-transition m.terials

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Frontiers of Optoelectronics 2024年第2期17卷 23-32页

作者： Zhixiang Huang Weipeng Wu Eric Herrm.nn Ke m. Zizwe A.Chase thomas A.Searles m.Benjam.n Jungfleisch Xi Wang Departm.nt of m.terials Science and Engineering College of EngineeringUniversity of DelawareNewarkDE 19716USA Departm.nt of Physics and Astronom. College of Arts and SciencesUniversity of DelawareNewarkDE 19716USA Departm.nt of Electrical and Com.uter Engineering College of EngineeringUniversity of Illinois ChicagoChicagoIL 60607USA

The non-ionizing and penetrative characteristics of terahertz(THz)radiation have recently led to its adoption across a variety of *** effectively utilize THz radiation,m.dulators with precise control are *** m.st recent THz m.dulators m.nipulate the am.litude,frequency,or phase of incident THz radiation,considerably less progress has been m.de toward THz polarization *** m.thods for polarization control suffer from.high driving voltages,restricted m.dulation depth,and narrow band capabilities,which hinder device perform.nce and broader ***,an ideal THz m.dulator that offers high m.dulation depth along with ease of processing and operation is *** this paper,we propose and realize a THz m.tam.terial com.rised of m.croelectrom.chanical system.(m.m.)actuated by the phase-transition m.terial vanadium.dioxide(VO_(2)).Sim.lation and experim.ntal results of the three-dim.nsional m.tam.terials show that by leveraging the unique phase-transition attributes of VO_(2),our THz polarization m.dulator offers notable advancem.nts over existing designs,including broad operation spectrum.high m.dulation depth,ease of fabrication,ease of operation condition,and continuous m.dulation *** enhanced features m.ke the system.a viable candidate for a range of THz applications,including telecom.unications,im.ging,and radar system..

关键词： m.tam.terials m.m. THz VO_(2) Phase-transition m.terial

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流行性出血热内生肌酐清除率的检测与临床意义

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中华内科杂志 1987年第8期26卷 458-460+509页

作者：袁光辉管美英巫振欧周文华张天衡王德芳刘新梅 Huggins John W. cosgriff thomas m. Sm.th Joseph I. 湖北医学院附属第一医院传染病教研室湖北医学院出血热实验室湖北省武昌县人民医院传染科湖北省成宁市人民医院传染科美国陆军军事医学传染病研究所

本文对46例各型流行性出血热(EHF)患者各期进行了内生肌酐清除率(Ccr)的动态检测。结果表明, Ccr的检测, 能在早期发现肾功能受损并能监测肾功能恢复, 对中、重型患者尤为明显。根据Ccr在发热期即开始下降, 至低血压期、少尿期达最低值,... 详细信息

本文对46例各型流行性出血热(EHF)患者各期进行了内生肌酐清除率(Ccr)的动态检测。结果表明, Ccr的检测, 能在早期发现肾功能受损并能监测肾功能恢复, 对中、重型患者尤为明显。根据Ccr在发热期即开始下降, 至低血压期、少尿期达最低值, 以后逐渐回升的动态变化, 表明Ccr降低与病情轻重呈正相关。在恢复期患者出院时Ccr均值未恢复正常者达27.5%。

关键词：肌酸酐/血液肾综合征出血热/血液