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Theoretical and Experimental Research on Error Analysis and Optimization of Tool Path in Fabricating Aspheric Compound Eyes by Precision Micro Milling

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Chinese Journal of Mechanical Engineering 2014年第3期27卷 558-566页

作者： CHEN Mingjun XIAO Yong TIAN Wenlan WU chunya CHU Xin Center for Precision Engineering Harbin institute of technology

Structure design and fabricating methods of three-dimensional （3D） artificial spherical compound eyes have been researched by many scholars. Micro-nano optical manufacturing is mostly used to process 3D artificial compound eyes. However, spherical optical compound eyes are less at optical performance than the eyes of insects, and it is difficult to further improve the imaging quality of compound eyes by means of micro-nano optical manufacturing. In this research, nonhomogeneous aspheric compound eyes （ACEs） are designed and fabricated. The nonhomogeneous aspheric structure is applied to calibrate the spherical aberration. Micro milling with advantages in processing three-dimensional micro structures is adopted to manufacture ACEs. In order to obtain ACEs with high imaging quality, the tool paths are optimized by analyzing the influence factors consisting of interpolation allowable error, scallop height and tool path pattern. In the experiments, two kinds of ACEs are manufactured by micro-milling with different too path patterns and cutting parameter on the miniature precision five-axis milling machine tool. The experimental results indicate that the ACEs of high surface quality can be achieved by circularly milling small micro-lens individually with changeable cutting depth. A prototype of the aspheric compound eye （ACE） with surface roughness （Ra） below 0.12 p.m is obtained with good imaging performance. This research ameliorates the imaging quality of 3D artificial compound eyes, and the proposed method of micro-milling can improve surface processing quality of compound eyes.

关键词： aspheric compound eyes (ACEs) micro milling tool path optimization

双钳道胃镜在内镜下全层切除术穿孔闭合中的应用

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潍坊医学院学报 2023年第5期45卷 385-387页

作者：邱凤娇袁文杰王春芽董秀红庄晓惠李蕾张红梅潍坊医学院附属医院消化内科山东潍坊261031

目的探讨运用双钳道胃镜在内镜下全层切除术治疗胃黏膜下肿瘤封闭穿孔中的应用价值。方法选择43例起源于固有肌层及以下的胃黏膜下肿瘤行内镜下全层切除术治疗,选择双钳道胃镜(双钳道组)或者尼龙绳辅助金属夹(尼龙绳组)进行闭合穿孔,比... 详细信息

目的探讨运用双钳道胃镜在内镜下全层切除术治疗胃黏膜下肿瘤封闭穿孔中的应用价值。方法选择43例起源于固有肌层及以下的胃黏膜下肿瘤行内镜下全层切除术治疗,选择双钳道胃镜(双钳道组)或者尼龙绳辅助金属夹(尼龙绳组)进行闭合穿孔,比较两组治疗效果。结果43例患者全部顺利完成内镜下全层切除术,两组在年龄、性别、肿瘤直径、穿孔直径方面差异均无统计学意义(P>0.05)。双钳道组在封闭过程中钛夹使用数量为(6.00±1.78)个,尼龙绳组为(7.20±1.32)个(t=-2.47,P0.05)。双钳道组术后住院天数为(6.26±1.51)d,尼龙绳组为(7.27±1.03)d(t=-2.07,P0.05)。结论应用双钳道胃镜行内镜下全层切除术治疗起源于固有肌层及以下的胃黏膜下肿物安全实用,创伤小,费用低,疗效满意,值得临床推广应用。

关键词：双钳道胃镜尼龙绳辅助金属夹胃黏膜下肿瘤内镜下全层切除术

A Novel Recovery Strategy to Suppress Subsequent Commutation Failure in an LCC-Based HVDC

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Protection and Control of Modern Power Systems 2024年第1期9卷 38-51页

作者： Changsheng Su chunya Yin Fengting Li Lu Han 不详 School of Electrical Engineering Xinjiang UniversityUrumqi 830017China

A subsequent commutation failure(SCF)can easily occur during the recovery process after a first commutation failure(1st CF).This paper analyzes the interaction mechanism of extinction angle,AC voltage,DC current and firing angle,and reveals that the complex coupling relationship during the dynamic process after the 1st CF has a significant effect on the *** mathematical equations when considering different fault durations,fault severities and AC system strengths are then *** AC fault voltage detection method based on reactive power and fault duration is also proposed to measure the fault severity,and an SCF inhibition control strategy(SCFICS)based on AC fault detection and reactive power control is subsequently *** can not only inhibit the SCF,but also enhance the DC recovery speed ***,based on the SCFICS,a simulation model is built,and the simulation results with different cases indicate that the SCFICS can effectively inhibit the SCF with good recovery performance,for three-phase-to-ground(TPG)and single-phase-to-ground faults,and with a fault inductance range of 0.01 H to 1 H.

关键词： fault extinction angle

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多功能能量管理电子纺织品的可印刷智能图案

科学新闻 2020年第2期 130-130页

作者：翟俊宜张莹莹 Mingchao Zhang Mingyu Zhao Muqiang Jian chunya wang Aifang Yu Zhe Yin Xiaoping Liang Huimin wang Kailun Xia Xiao Liang 中国科学院北京纳米能源与系统研究所清华大学化学系

文章简介近年来,随着柔性和可穿戴电子产品的发展,电子纺织品(E-Texture)引起了人们极大的关注。课题组在研究中发现,利用配备同轴喷丝板的3D打印机可直接打印由芯鞘纤维组成的电子纺织品,客户出于各种目的设计的芯鞘纤维图案都可以印... 详细信息

文章简介近年来,随着柔性和可穿戴电子产品的发展,电子纺织品(E-Texture)引起了人们极大的关注。课题组在研究中发现,利用配备同轴喷丝板的3D打印机可直接打印由芯鞘纤维组成的电子纺织品,客户出于各种目的设计的芯鞘纤维图案都可以印制在纺织品上。作为演示,课题组以碳纳米管(CNTs)为导电核心,丝素蛋白(SF)为介电护套,制备了CNTs@SF芯鞘纤维智能图案,并将其进一步用作摩擦电纳米发电机纺织品。这种智能纺织品可以从人体运动中获取生物

关键词：电子纺织品

Combining radiation and the ATR inhibitor berzosertib activates STING signaling and enhances immunotherapy via inhibiting SHP1 function in colorectal cancer

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Cancer Communications 2023年第4期43卷 435-454页

作者： Chaofan Liu Xi wang Wan Qin Jingyao Tu chunya Li Weiheng Zhao Li Ma Bo Liu Hong Qiu Xianglin Yuan Department of Oncology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubeiP.R.China

Background:Immune checkpoint inhibitors(ICIs)targeting programmed cell death protein 1(PD-1)and programmed death-ligand 1(PD-L1)have shown a moderate response in colorectal cancer(CRC)with deficient mismatch repair(dMMR)functions and poor response in patients with proficientMMR(pMMR).pMMRtumors are generally immunogenically“cold”,emphasizing combination strategies to turn the“cold”tumor“hot”to enhance the efficacy of *** inhibitors(ATRi)have been proven to cooperate with radiation to promote antitumor immunity,but it is unclear whether ATRi could facilitate the efficacy of IR and ICI combinations in *** study aimed to investigate the efficacy of combining ATRi,irradiation(IR),and anti-PD-L1 antibodies in CRC mouse models with different microsatellite ***:The efficacy of combining ATRi,IR,and anti-PD-L1 antibodies was evaluated in CRC *** tumor microenvironment and transcriptome signatures were investigated under different treatment *** mechanisms were explored via cell viability assay,flow cytometry,immunofluorescence,immunoblotting,co-immunoprecipitation,and real-time quantitative PCR in multiple murine and human CRC cell ***:Combining ATRi berzosertib and IR enhanced CD8+T cell infiltration and enhanced the efficacy of anti-PD-L1 therapy in mouse CRC models with different microsatellite *** mechanistic study demonstrated that IR+ATRi could activate both the canonical cGAS-STING-pTBK1/pIRF3 axis by increasing cytosolic double-stranded DNA levels and the non-canonical STING signaling by attenuating SHP1-mediated inhibition of the TRAF6-STINGp65 axis,via promoting SUMOylation of SHP1 at lysine *** boosting the STING signaling,IR+ATRi induced type I interferon-related gene expression and strong innate immune activation and reinvigorated the cold tumor microenvironment,thus facilitating ***:The combination of ATRi and IR could facilitate anti-PD-L1 therapy by promoting STING signaling i

关键词： colorectal cancer ATR inhibitor radiotherapy immune checkpoint inhibitor PD-L1 innate immunity cGAS-STING DNA damage SHP1 SUMOylation

Research on the influence of machining introduced sub-surface defects and residue stress upon the mechanical properties of single crystal copper

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Science China(Technological Sciences) 2010年第12期53卷 3161-3167页

作者： CHEN MingJun, XIAO GaoBo, CHEN JiaXuan & WU chunya Harbin Institute of Technology, Harbin 150001, China Harbin Institute of Technology Harbin China

Large scale molecular dynamics simulations of nanomachining and stretching of single crystal copper are performed to analyze the machining process’ influence on the material’s mechanical properties. The simulation results show that the machining process will introduce interfacial defects inside the specimen and enhance the compressive stress beneath the surface. Gener- ally speaking, interfacial defects lead to the decrease of the strength limit, while residue compressive stress can enhance the elastic limit and even the strength limit. Various machining parameters are adopted to investigate their influence on the me- chanical behavior of machined specimen. Lower cutting speed and smaller cutting depth lead to less defects and greater residue compressive stress, which brings about better mechanical properties. The elastic limit increases by 36.8% under the cutting depth of 0.73 nm and decreases by 21.1% under the cutting depth of 1.46 nm. The strength limit increases by 7.7% under the cutting speed of 100 m/s and decreases by 28.2% under the cutting speed of 300 m/s.

关键词： nanomachining deformation residue stress molecular dynamics dislocations

Towards high performance polyimide cathode materials for lithium–organic batteries by regulating active-site density,accessibility,and reactivity

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eScience 2024年第4期4卷 110-119页

作者： Jun wang Haichao Liu chunya Du Bing Liu Haoran Guan Yu Liu Shaowei Guan Zhenhua Sun Hongyan Yao National&Local Joint Engineering Laboratory for Synthesis Technology of High Performance Polymer Key Laboratory of High Performance PlasticsMinistry of EducationCollege of ChemistryJilin UniversityChangchun 130012China State Key Lab of Supramolecular Structure and Materials Jilin UniversityChangchun 130012China Shenyang National Laboratory for Materials Science Institute of Metal Research Chinese Academy of SciencesShenyang 110016China College of Sciences Shenyang University of Chemical TechnologyShenyang 110142China

Organic carbonyl electrode materials offer promising prospects for future energy storage systems due to their high theoretical capacity,resource sustainability,and structural *** much progress has been made in the research of high-performance carbonyl electrode materials,systematic and in-depth studies on the underlying factors affecting their electrochemical properties are rather ***,five polyimides containing different types of diamine linkers are designed and synthesized as cathode materials for Li-ion ***,the incorporation of carbonyl groups increases the active-site density in both conjugated and non-conjugated ***,increased molecular rigidity can improve the accessibility of the active ***,the introduction of the conjugated structure between two carbonyl groups can increase the reactivity of the active ***,the incorporation of carbonyl structures and conjugated structures increases the capacity of ***,PAN,PMN,PSN,and PBN exhibit 212,198,199,151,and 115mAh g^(−1)at 50mAg^(−1),*** addition,the introduction of a carbonyl structure and a conjugated structure is also beneficial for improving cycling stability and rate *** work can deepen the understanding of the structure–function relationship for the rational design of polyimide electrode materials and can be extended to the molecular design of other organic cathode materials.

关键词： Organic cathode materials Polymer electrode Lithium-ion batteries Carbonyl Polyimides

Utilizing morpholine for purely organic room temperature phosphors

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Science China Chemistry 2023年第4期66卷 1132-1138页

作者： Dongyan Jiang Tong Lu chunya Du Futong Liu Zhenyu Yan Dehua Hu Anqi Shang Lei Gao Ping Lu Yuguang Ma State Key Laboratory of Supramolecular Structure and Materials Department of ChemistryJilin UniversityChangchun 130012China Institute of Polymer Optoelectronic Materials and Devices State Key Laboratory of Luminescent Materials and DevicesSouth China University of TechnologyGuangzhou 510640China

In this article,morpholine,a non-conjugated heterocycle,is embedded intoπsystem to construct single-component organic room temperature phosphorescence(RTP)*** effect of morpholine on intermolecular interaction,crystal packing modes,and RTP performance is investigated *** experimental and theoretical calculation results illustrate the versatility of morpholine in promoting the n-π*transition and intensifying the intermolecular interactions,which not only enhances the generation of triplet excitons,but also suppresses the nonradiative decay of triplet ***,TMPh containing three morpholine units shows an ultralong lifetime of 1.03 s and a visible afterglow up to 10 *** unique dual delayed emission and long afterglow property allow potential application of morpholine derivatives in data encryption,and the time-dependent color change of afterglow emission is realized after removing the excitation source,providing a high-level data *** article provides a new perspective for the design of purely organic RTP system without utilization of metal,or even any heavy atoms.

关键词： morpholine room temperature phosphorescence aggregation noncovalent interactions thermally activated delayed fluorescence

Walking Cations: Transition-Metal Free Benzyl Cation-Triggered sp^(2) C—H Phosphorylation and Etherification

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Chinese Journal of Chemistry 2022年第24期40卷 2933-2938页

作者： Kuan Liu Bin Song Qi Dang Long Liu Jie Tang Tianzeng Huang chunya Li Zhi Tang Tieqiao Chen Key Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources Hainan Provincial Key Lab of Fine ChemHainan Provincial Fine Chemical Engineering Research CenterHainan UniversityHaikouHainan570228 China

A novel benzyl cation-triggered site-selective sp^(2) C—H phosphorylation and etherification was developed. This reaction was conducted under the transition metal-free conditions through cation migration via dearomatization. Under the reaction conditions, the derivatives of naphthalenes, benzofurans and benzo[b]thiophenes all can be transformed into the corresponding products in good to excellent yields. It provides a method to construct sp^(2) C—P and sp^(2) C—O bonds as well as a new strategy for benzylic activation-triggered sp^(2) C—H functionalization.

关键词： Transition metal-free Cation migration Site-selectivity Phosphorylation Etherification