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上海市白血病主要亚型发病特征和趋势分析

诊断学理论与实践 2017年第5期16卷 484-491页

作者：鲍萍萍吴春晓张敏璐顾凯向詠梅彭鹏龚杨明施亮邹珍上海市疾病预防控制中心慢性非传染病和伤害防治所上海200336

目的:分析2008年至2012年上海市白血病及其主要亚型的流行病学特征和上海市市区1973年至2012年的白血病发病趋势,为探寻病因学研究线索,制定和评估白血病预防、研究与控制的规划和措施提供依据。方法:根据上海市恶性肿瘤病例报告登记系... 详细信息

目的:分析2008年至2012年上海市白血病及其主要亚型的流行病学特征和上海市市区1973年至2012年的白血病发病趋势,为探寻病因学研究线索,制定和评估白血病预防、研究与控制的规划和措施提供依据。方法:根据上海市恶性肿瘤病例报告登记系统收集的白血病发病资料,描述患者的发病概况及性别、年龄和各亚型分布,并应用Joinpoint统计软件进行趋势分析,估算总体和分阶段的年度变化百分比(annual percent change,APC)。标化率采用世界人口构成为标准。结果:2008年至2012年,上海全市共新诊断白血病病例4 404例,占所有部位恶性肿瘤的1.53%。男、女性的白血病粗发病率分别为6.78/10万和5.75/10万,标化发病率为5.14/10万和4.11/10万,男性标化发病率高于女性(X=3.16,P<0.01)。急性髓细胞白血病(acute myelogenous leukemia,AML)是最常见的白血病亚型,占18.30%,其次为急性淋巴细胞白血病(acute lymphoblastic leukemia,ALL)、慢性髓细胞白血病(chronic myelocytic leukemia,CML)和慢性淋巴细胞白血病(chronic lymphocytic leukemia,CLL)。除ALL外,各亚型白血病的年龄别发病率均随着年龄的增长而升高;ALL的发病年龄相对较早,年龄别发病率表现出随年龄的增长发病率下降,0~5岁组是发病高峰。1973年至2012年期间的总白血病标化发病率,男性无明显变化趋势,而女性标化发病率则明显下降,APC为-0.39%;不同亚型的发病趋势不同,男性ALL的发病率上升(APC为1.12%),男性和女性CLL的发病率均呈明显上升趋势,而男、女性AML的发病率则在这40年间均显著下降,平均APC分别为-2.04%和-2.00%。结论:上海白血病发病率接近全球平均水平,男性比女性多发,AML是最常见的亚型,ALL的发病年龄相对较早。1973年至2012年期间,男性白血病发病率无明显变化,女性则显著下降,不同亚型变化趋势不同。

关键词：白血病亚型发病趋势流行病学肿瘤登记上海

Stacking monolayers at will:A scalable device optimization strategy for two-dimensional semiconductors

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Nano Research 2022年第7期15卷 6620-6627页

作者： Xiaojiao Guo Honglei Chen Jihong Bian Fuyou Liao Jingyi Ma Simeng Zhang Xinzhi Zhang Junqiang Zhu Chen Luo Zijian Zhang Lingyi Zong Yin Xia Chuming Sheng Zihan Xu Saifei Gou Xinyu Wang Peng Gong Liwei Liu Xixi Jiang Zhenghua An chunxiao Cong Zhijun Qiu Xing wu Peng Zhou Xinyu Chen Ling Tong Wenzhong Bao State Key Laboratory of ASIC and System School of MicroelectronicsZhangjiang Fudan International Innovation CenterFudan UniversityShanghai 200433China The Hong Kong Polytechnic University Shenzhen Research Institute Shenzhen 518057China Department of Physics State Key Laboratory of Surface PhysicsInstitute of Nanoelectronic Devices and Quantum Computing and Key Laboratory of MicroFudan UniversityShanghai 200433China State Key Laboratory of ASIC and System School of Information Science and EngineeringFudan UniversityShanghai 200433China Shanghai Key Laboratory of Multidimensional Information Processing Department of Electronic Engineering East China Normal UniversityShanghai 200241China Shenzhen Six Carbon Technology Shenzhen 518055China Department of Chemistry and Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials Fudan UniversityShanghai 200433China

In comparison to monolayer(1L),multilayer(ML)two-dimensional(2D)semiconducting transition metal dichalcogenides(TMDs)exhibit more application potential for electronic and optoelectronic devices due to their improved current carrying capability,higher mobility,and broader spectral ***,the investigation of devices based on wafer-scale ML-TMDs is still restricted by the synthesis of uniform and high-quality ML *** this work,we propose a strategy of stacking MoS_(2) monolayers via a vacuum transfer method,by which one could obtain wafer-scale high-quality MoS_(2) films with the desired number of layers at *** optical characteristics of these stacked ML-MoS_(2) films(>2L)indicate a weak interlayer *** stacked MLMoS_(2) phototransistors show improved optoelectrical performances and a broader spectral response(approximately 300-1,000 nm)than that of 1L-MoS_(2).Additionally,the dual-gate ML-MoS_(2) transistors enable enhanced electrostatic control over the stacked ML-MoS_(2) channel,and the 3L and 4L thicknesses exhibit the optimal device performances according to the turning point of the current on/off ratio and the subthreshold swing.

关键词： two-dimensional semiconductor field-effect transistors chemical vapor deposition(CVD)synthesis interlayer coupling vacuum transfer method dual-gate transistor

125I粒子组织间分次植入治疗晚期肺癌临床研究

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山西医药杂志 2019年第23期48卷 2855-2857页

作者：包祺张泽良俞杞权张琨吴春晓郭文韬寿伟臻上海中医药大学附属龙华医院胸外科

目的探讨不同方式及次数的125I粒子植入治疗肺癌的临床疗效情况。目的观察125I粒子组织间分次植入治疗晚期肺癌临床疗效。方法选择我院2013年10月至2017年3月收治的44例晚期肺癌患者,分成单次125I植入与多次125I植入2组,观察其临床疗效... 详细信息

目的探讨不同方式及次数的125I粒子植入治疗肺癌的临床疗效情况。目的观察125I粒子组织间分次植入治疗晚期肺癌临床疗效。方法选择我院2013年10月至2017年3月收治的44例晚期肺癌患者,分成单次125I植入与多次125I植入2组,观察其临床疗效在不同手术方式、不同肿瘤部位时的差异。结果分次植入组患者的近期有效率效明显优于单次植入组(P<0.01);不同手术方式,不同肿瘤部位在疗效上无明显差异。结论125I粒子组织间分次植入治疗晚期肺癌是一种安全、有效、微创的治疗手段,尤其在巨大的肺癌患者中不失为一种可选择的方法。

关键词：肺肿瘤碘植入

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《抽彩》赏析(英文)

科技信息 2008年第13期 181-181,214页

作者：吴荣辉张欢吴春晓华南农业大学外国语学院广东广州510642 华南农业大学继续教育学院广东广州510642

《抽彩》讲述美国的一个普通小村镇的古老传统仪式:村民们每年举行一次抽彩活动,抽出中彩者用乱石打死来保证收获。雪利·杰克逊用独特的风格揭示人性的残忍、不仁道和社会对个体的迫害,因此引起许多争议。本文分析《抽彩》的冲突、背... 详细信息

《抽彩》讲述美国的一个普通小村镇的古老传统仪式:村民们每年举行一次抽彩活动,抽出中彩者用乱石打死来保证收获。雪利·杰克逊用独特的风格揭示人性的残忍、不仁道和社会对个体的迫害,因此引起许多争议。本文分析《抽彩》的冲突、背景、人物塑造、象征和讽刺手法。

关键词：《抽彩》人物塑造讽刺雪利·杰克

Intrinsic excitonic emission and valley Zeeman splitting in epitaxial MS2(M=Mo and W)monolayers on hexagonal boron nitride

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Nano Research 2018年第12期11卷 6227-6236页

作者： chunxiao Cong Chenji Zou Bingchen Cao Lishu wu Jingzhi Shahg Haomin Wang Zhijun Qiu Laigui Hu Pengfei Tian Ran Liu Ting Yu State Key Laboratory of ASIC and System School of Information Science and TechnologyFudan UniversityShanghai 200433China Division of Physics and Applied Physics School of Physical and Mathematical SciencesNanyang Technological UniversitySingapore 637371Singapore State Key Laboratory of Functional Materials for Informatics Shanghai Institute of Microsystem and Information TechnologyChinese Academy of Sciences865Changning RoadShanghai200050China

Two-dimensional (2D) semiconductors, represented by 2D transition metal dichalcogenides (TMDs), exhibit rich valley physics due to strong spin-orbit/spin-valley coupling. The most common way to probe such 2D systems is to utilize optical methods, which can monitor light emissions from various excitonic states and further help in understanding the physics behind such phenomena. Therefore, 2D TMDs with good optical quality are in great demand. Here, we report a method to directly grow epitaxial WS2 and MoS2 monolayers on hexagonal boron nitride (hBN) flakes with a high yield and high optical quality; these monolayers show better intrinsic light emission features than exfoliated monolayers from natural crystals. For the first time, the valley Zeeman splitting of WS2 and MoS2 monolayers on hBN has been visualized and systematically investigated. This study paves a new way to produce high optical quality WS2 and MoS2 monolayers and to exploit their intrinsic properties in a multitude of applications.

关键词： transition metal dichalcogenides intrinsic excitonic emission valley Zeeman splitting hexagonal boron nitride chemical vapor deposition

Raman scattering investigation of twisted WS_(2)/MoS_(2) heterostructures: interlayer mechanical coupling versus charge transfer

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Nano Research 2021年第7期14卷 2215-2223页

作者： Lishu wu chunxiao Cong Jingzhi Shang Weihuang Yang Yu Chen Jiadong Zhou Wei Ai Yanlong Wang Shun Feng Hongbo Zhang Zheng Liu Ting Yu Division of Physics and Applied Physics School of Physical and Mathematical SciencesNanyang Technological UniversitySingapore 637371Singapore School of Information Science and Technology Fudan UniversityShanghai 200433China Shaanxi Institute of Flexible Electronics Northwestern Polytechnical UniversityXi’an 710129China Engineering Research Center of Smart Microsensors and Microsystems Ministry of EducationCollege of Electronics and InformationHangzhou Dianzi UniversityHangzhou 310018China School of Materials Science and Engineering Nanyang Technological UniversitySingapore 639798Singapore Key Laboratory of Chemical Lasers Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China

Twisted van der Waals homo-and hetero-structures have aroused great attentions due to their unique physical properties,providing a new platform to explore the novel two-dimensional(2D)condensed matter *** robust dependence of phonon vibrations and electronic band structures on the twist angle has been intensively observed in transition metal dichalcogenide(TMD)***,the effects of twist angle on the lattice vibrational properties in the TMD heterostructures have not caused enough ***,we report the distinct evolutions of Raman scattering and the underlying interlayer interactions in the twisted WS_(2)/MoS_(2) *** shifts and linewidths of E_(2g)(Γ)and A_(1g)(Γ)phonon modes are found to be twist angle *** particular,analogous to that of the twisted TMD homostructures,the frequency separations between E_(2g)(Γ)and A_(1g)(Γ)modes of MoS_(2) and WS_(2) in the twisted heterostructures varying with twist angle correlate with the interlayer mechanical coupling,essentially originating from the spacing-related repulsion between sulfur ***,the opposite shift behaviors and broadening of A_(1g)(Γ)modes caused by charge transfer are also observed in the twisted *** calculated interlayer distances and band alignment of twisted WS_(2)/MoS_(2) through density functional theory further evidence our interpretations on the roles of the interlayer mechanical coupling and charge transfer in variations of Raman *** understanding and controlling of interlayer interaction through the stacking orientation are significant for future optoelectronic device design based on the newly emerged 2D heterostructures.

关键词： van der Waals heterostructures interlayer coupling Raman scattering twist angle charge transfer

公共会计行业自律监管的人力资源配置与同业互查质量--来自中注协上市公司审计质量检查的证据

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审计研究 2023年第1期 73-84页

作者：吴溪李诗依耿春晓中央财经大学会计学院/中国管理会计研究与发展中心 100081 中央财经大学会计学院 100081 山东大学经济学院 250100

本文考察了我国注册会计师行业围绕上市公司年审开展的同业互查质量如何受到所配置专业检查人员过往经验的影响。尽管质量复核的原则是检查人员的执业经验应高于被检查人员,但受监管资源约束,现实运行中前者经验低于后者的情形也较为普... 详细信息

本文考察了我国注册会计师行业围绕上市公司年审开展的同业互查质量如何受到所配置专业检查人员过往经验的影响。尽管质量复核的原则是检查人员的执业经验应高于被检查人员,但受监管资源约束,现实运行中前者经验低于后者的情形也较为普遍。基于2007-2017年同业互查数据,我们发现当检查人员过往担任上市公司年审负责人的经验低于被检查项目负责人时,实际惩戒结果和预期惩戒概率之间的偏差幅度更大。当检查人员以往参加过同业互查,或来自质量控制岗,或来自规模较大事务所时,检查人员执业经验不足伴随的惩戒决策偏误得到显著缓解。本文展示了在监管资源约束下合理配置检查人员对提升监督质量的价值,对完善注册会计师行业自律监管体系具有参考意义。

关键词：公共会计行业自律监管同业互查人力资源配置监督质量

Spatial variations of valley splitting in monolayer transition metal dichalcogenide

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InfoMat 2020年第3期2卷 585-592页

作者： Chenji Zou Hongbo Zhang Yu Chen Shun Feng Lishu wu Jing Zhang Ting Yu Jingzhi Shang chunxiao Cong Division of Physics and Applied Physics School of Physical and Mathematical SciencesNanyang Technological UniversitySingaporeSingapore Institute of Flexible Electronics Northwestern Polytechnical UniversityXi'anShaanxiChina State Key Laboratory of ASIC and System School of Information Science and TechnologyFudan UniversityShanghaiChina

In monolayer group-VI transition metal dichalcogenides(TMDs),valley splitting features have received a lot of attention since it can be potentially utilized for information storing and *** the known two-dimensional(2D)TMDs,monolayer WSe2 or MoSe2 has been mostly selected for excitonic and valleytronic physics studies because of its sharp and well-resolved excitonic spectral ***,their high optical quality leads to a tremendous desire for developing promising WSe2-and MoSe2-based valleytronic *** this goal,exploring the uniformity of valley features crossing an entire piece of monolayer becomes necessary and ***,we performed the systematic magnetophotoluminescence mapping measurements on mechanically exfoliated monolayer WSe2 and observed unconventional spatial variations of valley *** observed nonuniformity is attributed to the modulated doping,which is probably due to the different distributions of unintentional absorbates across the *** an unexpected doping effect shows the nonnegligible influence on the valley Zeeman splitting of the trion emission(XT)while affecting that of the neutral exciton emission(X0)trivially,evidencing for the large valleytronic sensitivity of the charged *** work not only enriches the understanding of the doping effect on valley splitting but also is meaningful for developing 2D valleytronics.

关键词： doping effect monolayer WSe2 photoluminescence transition metal dichalcogenide valley splitting

上海市区1973年至2007年结肠直肠癌的发病趋势

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诊断学理论与实践 2014年第4期13卷 377-382页

作者：顾凯吴春晓龚杨明彭鹏鲍萍萍向詠梅黄哲宙郑莹仲伟鉴上海市疾病预防控制中心上海200336

目的：按照性别、年龄段和发病部位,分析1973年至2007年上海市区结肠直肠癌的发病趋势。方法：数据来源于上海市肿瘤登记报告系统。按照世界标准人口计算结肠直肠癌年龄标化发病率,使用Joinpoint回归模型计算年度变化百分比（annual per... 详细信息

目的：按照性别、年龄段和发病部位,分析1973年至2007年上海市区结肠直肠癌的发病趋势。方法：数据来源于上海市肿瘤登记报告系统。按照世界标准人口计算结肠直肠癌年龄标化发病率,使用Joinpoint回归模型计算年度变化百分比（annual percentage change,APC）。结果：直肠癌是最常见的结肠直肠癌亚部位,但直肠癌的构成比从1973年至1977年的66.5%,下降至2003年至2007年的44.4%。远端结肠癌标化发病率的APC最高（男性为5.3%,女性为4.9%）,其次是近端结肠癌（男性为4.1%,女性为4.2%）,直肠癌的APC最低（男性为1.5%,女性为1.1%）。女性远端结肠癌和直肠癌发病率在30~39岁年龄段出现了显著下降的趋势（APC分别为-3.8%和-2.8%）,男性直肠癌发病率在30~39岁年龄段也出现了显著下降趋势（APC为-1.9%）。结论：1973年至2007年上海市区结肠直肠癌发病总体呈现上升趋势,其中结肠癌发病上升更为显著,而乙状结肠癌和升结肠癌发病增加是结肠癌构成比上升的最主要因素。在低年龄段人群中,开始出现男性直肠癌、女性直肠癌和远端结肠癌发病下降的趋势。

关键词：结肠直肠癌发病率发病趋势