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Communications in Theoretical Physics 2021年第1期73卷 117-121页

作者： chun-yu cai Wei Qiu Yong Sun Cui-Lan Zhao Jing-Lin Xiao Institute of Condensed Matter Physics Inner Mongolia University for NationalitiesTongliao 028043China

Because of its unique optoelectronic properties,people have studied the characteristics of polarons in various quantum well(QW)*** them,the asymmetrical semiexponential QW(ASEQW)is a new model for studying the structure of QWs in recent *** is of great significance to study the influences of the impurity and anisotropic parabolic confinement potential(APCP)on the crystal’s properties,because some of the impurities,usually regarded as Coulomb’s impurity potential(CIP),will exist in the crystal more or less,and the APCP has flexible adjustment ***,the energy characteristics of the ASEQW under the combined actions of impurities and APCP have not been studied,which is the motivation of this *** the linear combination operation and Lee-Low-Pines unitary transformation methods,we investigate the vibrational frequency and the ground state energy of the strong coupling polaron in an ASEQW with the influences of the CIP at the origin of coordinates and APCP,and make a comparison between our results and previous literature’*** numerical results about the energy properties in the ASEQW influenced by the CIP and APCP may have important significances for experimental design and device preparation.

关键词： asymmetrical semi-exponential quantum well anisotropic parabolic confinement potential vibrational frequency Coulombʼs impurity potential ground state energy

Clinical analysis of secondary penile cancer:a case series at a tertiary referral center in China

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Asian Journal of Andrology 2024年第2期26卷 225-226页

作者： Xiao-yu Li chun-Ru Xu Xing Ji Zhen-Peng Zhu Zhen-Ke Guo Tian-yu cai Jian Lin Department of Urology Peking University First HospitalBeijing 100034China Institute of Urology Peking UniversityBeijing 100034China National Urological Cancer Center Beijing 100034China Beijing Key Laboratory of Urogenital Diseases(Male)Molecular Diagnosis and Treatment Center Beijing 100034China

Dear Editor,Secondary penile cancer is an extremely rare condition that refers to the metastasis of other malignancies to the *** are limited reports on secondary penile cancer in Asian populations,and perceptions about this disease are extremely *** reviewed and analyzed the data of patients diagnosed with secondary penile cancer based on the pathological findings at Peking University First Hospital in Beijing,China,aiming to expand the clinical reference for this rare disease.

关键词： cancer rare finding

Interactions Between Extracellular Vesicles and Autophagy in Neuroimmune Disorders

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Neuroscience Bulletin 2024年第7期40卷 992-1006页

作者： Xiwen Ai Haojun yu yu cai Yangtai Guan Department of Neurology Shanghai Jiao Tong University School of Medicine Affiliated Renji HospitalShanghai 200127China Department of Neurology Renaissance School of MedicineStony Brook UniversityStony BrookNY 11794USA

Neuroimmune disorders,such as multiple sclerosis,neuromyelitis optica spectrum disorder,myasthenia gravis,and Guillain–Barrésyndrome,are characterized by the dysfunction of both the immune system and the nervous *** evidence suggests that extracellular vesicles and autophagy are closely associated with the pathogenesis of these *** this review,we summarize the current understanding of the interactions between extracellular vesicles and autophagy in neuroimmune disorders and discuss their potential diagnostic and therapeutic *** we highlight the need for further research to fully understand the mechanisms underlying these disorders,and to develop new diagnostic and therapeutic strategies.

关键词： Autophagy Extracellular vesicles Neuroimmune disorders Multiple sclerosis Neuromyelitis optica spectrum disorder Myasthenia gravis Guillain-Barré syndrome

HIV and intestinal parasite co-infections among a Chinese population: an immunological profile

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Infectious Diseases of Poverty 2013年第1期2卷 144-151,143页

作者： Li-Guang Tian Tian-Ping Wang Shan Lv Feng-Feng Wang Jian Guo Xiao-Mei Yin yu-chun cai Mary Kathryn Dickey Peter Steinmann Jia-Xu Chen National Institute of Parasitic Diseases Chinese Center for Disease Control and Prevention(China CDC) WHO Collaborating Centre for Malaria Schistosomiasis and FilariasisKey Laboratory of Parasite and Vector BiologyMinistry of HealthShanghai 200025People’s Republic of China Anhui Institute of Parasitic Disease Control Hefei 241000People’s Republic of China University of Oklahoma Midwest 73110OKUSA Department of Epidemiology and Public Health Swiss Tropical and Public Health Institu

Background:Parasite infections often result in a switch of the human body’s predominant immune reaction from T-helper 1(Th1)-type to ***,parasite infections are widely expected to accelerate the progression of human immunodeficiency virus(HIV)infections to acquired immunodeficiency syndrome(AIDS).In the People’s Republic of China,both parasitic diseases and AIDS are epidemic in certain rural areas,and co-infections are relatively ***,no population-based studies have yet investigated the frequency of HIV and parasite co-infections,and its effects on immune *** studied(1)the immune status of an HIV-infected population,and(2)the effect of co-infection of HIV and intestinal parasites on selected parameters of the human immune ***:A total of 309 HIV-infected individuals were recruited and compared to an age-matched and sex-matched control group of 315 local HIV-negative *** were administered to all participants to obtain information on sociodemographic characteristics,sanitation habits,family income,and recent clinical *** consecutive stool samples and 10 ml samples of venous blood were also collected from each individual for the diagnosis of parasite infections and quantitative measurements of selected cytokines and CD4+T-lymphocytes,***:During the study period,79 HIV-infected individuals were not under highly active antiretroviral therapy(HAART)and were thus included in our analysis;the prevalence of intestinal helminth infections was 6.3%and that of protozoa was 22.8%.The most common protozoan infections were Blastocystis hominis(***)(13.9%)and Cryptosporidium spp.(10.1%).The prevalence of Cryptosporidium *** HIV-infected individuals was significantly higher than that in HIV negative individuals(P0.05).However,the following trend

关键词： HIV Intestinalparasite Co-infection Immunological profile People’s Republic of China

Proteomics Study of Benzene Metabolite Hydroquinone Induced Hematotoxicity in K562 Cells

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Biomedical and Environmental Sciences 2024年第4期37卷 341-353页

作者： JIN Yi Shan YI Zong chun ZHANG yu Jing RONG Long yu chun Hong School of Biological Science and Medical Engineering Beihang UniversityBeijing 100191China School of Engineering Medicine Beihang UniversityBeijing 100191China

Objective Hydroquinone(HQ),one of the phenolic metabolites of benzene,is widely recognized as an important participant in benzene-induced ***,there are few relevant proteomics in HQ-induced hematotoxicity and the mechanism hasn’t been fully understood *** In this study,we treated K562 cells with 40μmol/L HQ for 72 h,examined and validated protein expression changes by Label-free proteomic analysis and Parallel reaction monitoring(PRM),and performed bioinformatics analysis to identify interaction *** One hundred and eighty-seven upregulated differentially expressed proteins(DEPs)and 279 downregulated DEPs were identified in HQ-exposed K562 cells,which were involved in neutrophilmediated immunity,blood microparticle,and other GO terms,as well as the lysosome,metabolic,cell cycle,and cellular senescence-related *** on the 23 DEGs and 5 DEPs in erythroid differentiation-related pathways,we constructed the network of protein interactions and determined 6 DEPs(STAT1,STAT3,CASP3,KIT,STAT5B,and VEGFA)as main hub proteins with the most interactions,among which STATs made a central impact and may be potential biomarkers of HQ-induced *** Our work reinforced the use of proteomics and bioinformatic approaches to advance knowledge on molecular mechanisms of HQ-induced hematotoxicity at the protein level and provide a valuable basis for further clarification.

关键词： Hydroquinone Proteomics Hematotoxicity K562 cells

Assembly of highly efficient aqueous light-harvesting system from sequence-defined peptoids for cytosolic microRNA detection

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Nano Research 2024年第2期17卷 788-796页

作者： Yang Song Xiaoli cai Mingming Wang Dan Du yuehe Lin chun-Long Chen Department of Mechanical and Materials Engineering Washington State UniversityPullmanWA 99164USA Division of Physical Sciences Pacific Northwest National LaboratoryRichlandWA 99352USA Department of Chemical Engineering University of WashingtonSeattleWA 98195USA

Precisely controlled spatial distributions of artificial light-harvesting systems in aqueous media are of significant importance for mimicking natural light-harvesting systems;however,they are often restrained by the solubility and the aggregation-caused quenching effect of the hydrophobic ***,we report one highly efficient artificial light-harvesting system based on peptoid nanotubes that mimic the hierarchical cylindrical structure of natural *** high crystallinity of these nanotubes enabled the organization of arrays of donor chromophores with precisely controlled spatial distributions,favoring an efficient Förster resonance energy transfer(FRET)process in aqueous *** FRET system exhibits an extremely high efficiency of 98.6%with a fluorescence quantum yield of 40%and an antenna effect of *** further demonstrated the use of this artificial light-harvesting system for quantifying miR-210 within cancer *** fluorescence intensity ratio of donor to acceptor is linearly related to the concentration of intercellular miR-210 in the range of 3.3–156 copies/*** high sensitivity in intracellular detection of miR-210 using this artificial light-harvesting system offers a great opportunity and pathways for biological imaging and detection,and for the further creation of microRNA(miRNA)toolbox for quantitative epigenetics and personalized medicine.

关键词： light-harvesting peptoid nanotube Förster resonance energy transfer intracellular RNA detection

Primordial black holes and curvature perturbations from false vacuum islands

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Science China(Physics,Mechanics & Astronomy) 2024年第9期67卷 58-72页

作者： Rong-Gen cai yu-Shi Hao Shao-Jiang Wang School of Physical Science and Technology Ningbo UniversityNingbo 315211China CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China Asia Pacific Center for Theoretical Physics Pohang 37673Republic of Korea

Recently,much attention has been focused on the false vacuum islands that are flooded by an expanding ocean of true-vacuum bubbles slightly later than most of the other parts of the *** delayed decay regions will accumulate locally larger vacuum energy density by staying in the false vacuum longer than those already transited into the true vacuum.A false vacuum island with thus acquired density contrast of a super-horizon size will evolve locally from radiation dominance to vacuum dominance,creating a local baby Universe that can be regarded effectively as a local closed *** such density contrasts of super-horizon sizes can ever grow large enough to exceed the threshold of gravitational collapse,primordial black holes will form similar to those collapsing curvature perturbations on super-horizon scales induced by small-scale enhancements during *** not,such density contrasts can still induce curvature perturbations potentially observable *** this paper,we revisit and elaborate on the generations of primordial black holes and curvature perturbations from delayed-decayed false vacuum islands during asynchronous first-order phase transitions with fitting formulas convenient for future model-independent studies.

关键词： first-order phase transitions primordial black holes curvature perturbations

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Chirality enables thermal magnon transistors

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Science China(Physics,Mechanics & Astronomy) 2024年第4期67卷 161-166页

作者： Tao yu Chengyuan cai Gerrit E.W.Bauer School of Physics Huazhong University of Science and TechnologyWuhan 430074China .WPI-AIMR and Institute for Materials Research and SCIS Tohoku UniversitySendai 980-8577Japan Kavli Institute for Theoretical Sciences University of Chinese Academy of SciencesBeijing 100190China

We report a theory of thermal spin pumping into proximity magnets under a transverse-bias-driven heat flow of magnons in magnetic films when the dipolar coupling to the magnetic gate is tuned to be “chiral”. While there is no rectification of the magnon current in the film, we predict that chirality diverts a large percentage(50% for perfect chirality) of it into the gate. This transverse thermal spin pumping effect can be controlled by rotating the film magnetization and may help manage the heat flow in future magnonic circuits.

关键词： magnon chirality quantum transport transistor

Dynamic Update Scheme of Spectrum Information Based on Spectrum Opportunity Incentive in the Database-Assisted Dynamic Spectrum Management

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China Communications 2024年第3期21卷 75-90页

作者： Zhang yu Chen Yong He Panfeng cai yueming Sixty-third Research Institute National University of Defense TechnologyNanjing 210007China College of Communications Engineering Army of Engineering UniversityNanjing 210007China

To solve the problem of delayed update of spectrum information(SI) in the database assisted dynamic spectrum management(DB-DSM), this paper studies a novel dynamic update scheme of SI in DB-DSM. Firstly, a dynamic update mechanism of SI based on spectrum opportunity incentive is established, in which spectrum users are encouraged to actively assist the database to update SI in real time. Secondly, the information update contribution(IUC) of spectrum opportunity is defined to describe the cost of accessing spectrum opportunity for heterogeneous spectrum users, and the profit of SI update obtained by the database from spectrum allocation. The process that the database determines the IUC of spectrum opportunity and spectrum user selects spectrum opportunity is mapped to a Hotelling model. Thirdly, the process of determining the IUC of spectrum opportunities is further modelled as a Stackelberg game by establishing multiple virtual spectrum resource providers(VSRPs) in the database. It is proved that there is a Nash Equilibrium in the game of determining the IUC of spectrum opportunities by VSRPs. Finally, an algorithm of determining the IUC based on a genetic algorithm is designed to achieve the optimal IUC. The-oretical analysis and simulation results show that the proposed method can quickly find the optimal solution of the IUC, and ensure that the spectrum resource provider can obtain the optimal profit of SI update.

关键词： database-assisted dynamic spectrum management Hotelling information updating contribution spectrum information updating Stackelberg

Context Processing in Contextual and Cued Fear Extinction

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Neuroscience Bulletin 2024年第6期40卷 835-839页

作者： Yimu Zhang chun Xu yu Gu State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science Institutes of Brain ScienceFudan UniversityShanghai200032China Institute of Neuroscience State Key Laboratory of NeuroscienceCenter for Excellence in Brain Science and Intelligence TechnologyChinese Academy of SciencesShanghai200031China

Anxiety disorders such as post-traumatic stress disorder(PTSD)are prevalent mental disorders that disturb millions *** disorders often manifest as excessive fear,anxiety,and distress,significantly impacting daily *** fear extinction paradigms in animals were established decades ago and have been widely used in research,providing a scientific basis for exposure therapies for anxiety disorders in humans.

关键词： distress disorders traumatic