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基于摄像机运动的简单虚拟场景生成

系统仿真学报 2004年第2期16卷 319-321,336页

作者：史迎春周献中丁泉刘哲王韬南京理工大学自动化系南京210094

利用摄像机标定技术和视频融合技术设计了一个基于摄像机运动的简单虚拟场景生成系统。首先对摄像机进行标定,然后利用摄像机的运动参数根据摄像机成像模型计算出3-D实景中特定的位置在2-D视频图像上的映射,最后利用映射结果对虚拟景物... 详细信息

利用摄像机标定技术和视频融合技术设计了一个基于摄像机运动的简单虚拟场景生成系统。首先对摄像机进行标定,然后利用摄像机的运动参数根据摄像机成像模型计算出3-D实景中特定的位置在2-D视频图像上的映射,最后利用映射结果对虚拟景物进行透视变换,并把它实时融合到视频图像特定位置中形成新的视觉效果,实现了一种类似于虚拟演播室的简单、有效、实用的视频制作新方法。实验表明该方法实时性好、生成的虚拟场景效果逼真。

关键词：虚拟场景:摄像机标定视频融合成像模型

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圆形蜂窝共面冲击力学性能

包装工程 2016年第19期37卷 27-32页

作者：付春英罗显洲孙德强天津职业大学天津300410 陕西科技大学西安710021

目的基于有限元模拟的方法,比较研究规则和交错排列的圆形蜂窝共面动态冲击力学性能。方法利用Ansys/LS-DYNA建立2种蜂窝的共面冲击分析有限元模型。结果借助于该模拟方法,分析得到在结构参数一致,冲击速度不同的情况下,规则排列的圆形... 详细信息

目的基于有限元模拟的方法,比较研究规则和交错排列的圆形蜂窝共面动态冲击力学性能。方法利用Ansys/LS-DYNA建立2种蜂窝的共面冲击分析有限元模型。结果借助于该模拟方法,分析得到在结构参数一致,冲击速度不同的情况下,规则排列的圆形蜂窝变形模式呈现3个阶段,即"X","V"和"一"字形,交错圆形蜂窝变形模式几乎相同,呈"一"字形。得出了2种排列方式的圆形蜂窝的变形模式转换速度与壁厚半径比的关系。根据有限元模拟结果,推导出了动态峰应力关于结构参数和冲击速度的经验公式。结论用有限元模拟的方法得到了2种排列方式的圆形蜂窝的共面冲击力学性能,为圆形蜂窝芯材的优化设计提供了参考依据。

关键词：圆形蜂窝芯材共面变形模式动态峰应力能量吸收有限元分析

Exploring gut microbiota as a novel therapeutic target in Crohn’s disease: Insights and emerging strategies

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World Journal of Gastroenterology 2025年第2期31卷 147-156页

作者： Tong Qiao xian-Hui Wen Department of Clinical Medicine Jinan UniversityGuangzhou 510632Guangdong ProvinceChina College of Life Science and Technology Jinan UniversityGuangzhou 510632Guangdong ProvinceChina

Extensive research has investigated the etiology of Crohn’s disease(CD),encompassing genetic predisposition,lifestyle factors,and environmental ***,the gut microbiome,recognized as the human body’s second-largest gene pool,has garnered significant attention for its crucial role in the patho-genesis of *** paper investigates the mechanisms underlying CD,focusing on the role of‘creeping fat’in disease progression and exploring emerging therapeutic strategies,including fecal microbiota transplantation,enteral nutri-tion,and therapeutic *** fat has been identified as a unique patho-logical feature of CD and has recently been found to be associated with dysbiosis of the gut *** characterize this dysbiotic state by identi-fying key microbiome-bacteria,fungi,viruses,and archaea,and their contributions to CD ***,this paper reviews contemporary therapies,empha-sizing the potential of biological therapies like fecal microbiota transplantation and dietary *** elucidating the complex interactions between host-microbiome dynamics and CD pathology,this article aims to advance our under-standing of the disease and guide the development of more effective therapeutic strategies for managing CD.

关键词： Crohn’s disease Gut microbiome Dysbiosis Creeping fat Fecal microbiota transplantation

中小型泄水工程利用附着混合流消能问题的探讨

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吉林水利 2003年第8期 15-17页

作者：马春英赵先玲吉林省水利水电勘测设计研究院吉林长春130021

本文介绍了混合流的概念,结合某一中型水库的试验,观测了混合流在抬高尾水时的下游流态,流速分布的变化规律以及对消能效果的影响。从而说明了低水头泄洪建筑物利用挑流消能有更多的可能性。

关键词：中小型泄水工程附着混合流消能自由混合流界限水深应用流态流速挑流水舌挑距

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高校管好用活固定资产意义与对策

贺州学院学报 2018年第2期34卷 118-120页

作者：刘迎春黄鲜桃广西科技大学广西柳州545006 广西医科大学审计处广西南宁530021

每一所高校的固定资产部分一般占总资产额70%以上。文章描述高校管好用活固定资产意义和固定资产管理现状,提出高校管好用活固定资产的几点对策措施,高校提升教学质量、提高科研水平、增强学生实践能力。

关键词：高校固定资产管好用活对策措施

Loss-of-function mutations of microRNA-142-3p promote ASH1L expression to induce immune evasion and hepatocellular carcinoma progression

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World Journal of Gastroenterology 2025年第1期31卷 126-145页

作者： Xing-Hui Yu Yan Xie Jian Yu Kun-Ning Zhang Zhou-Bo Guo Di Wang Zhao-xian Li Wei-Qi Zhang Yu-ying Tan Li Zhang Wen-Tao Jiang School of Medicine Nankai UniversityTianjin 300192China Tianjin Key Laboratory of Molecular Diagnosis and Treatment of Liver Cancer Tianjin First Center HospitalTianjin 300192China Department of Liver Transplantation Tianjin First Center HospitalTianjin 300192China First Central Clinical School Tianjin Medical UniversityTianjin 300192China

BACKGROUND Hepatocellular carcinoma(HCC)has been a pervasive malignancy throughout the world with elevated *** therapeutic targets are beneficial to treat and predict the ***,the exact molecular mechanisms leading to the progression of HCC are still *** has shown that the microRNA-142-3p level decreases in HCC,whereas bioinformatics analysis of the cancer genome atlas database shows the ASH1L expression increased among liver tumor *** this paper,we will explore the effects and mechanisms of microRNA-142-3p and ASH1L affect the prognosis of HCC patients and HCC cell bioactivity,and the association between *** To investigate the effects and mechanisms of microRNA-142-3p and ASH1L on the HCC cell bioactivity and prognosis of HCC *** In this study,we grouped HCC patients according to their immunohistochemistry results of ASH1L with pathological tissues,and retrospectively analyzed the prognosis of HCC ***,explored the roles and mechanisms of microRNA-142-3p and ASH1L by cellular and animal experiments,which involved the following experimental methods:Immunohistochemical staining,western blot,quantitative real-time-polymerase chain reaction,flow cytometric analysis,tumor xenografts in nude mice,*** statistical methods involved in this study contained t-test,one-way analysis of variance,theχ^(2)test,the Kaplan-Meier approach and the log-rank *** In this study,we found that HCC patients with high expression of ASH1L possess a more recurrence rate as well as a decreased overall survival ***1L promotes the tumorigenicity of HCC and microRNA-142-3p exhibits reduced expression in HCC tissues and interacts with ASH1L through targeting the ASH1L 3′untranslated ***,microRNA-142-3p promotes apoptosis and inhibits proliferation,invasion,and migration of HCC cell lines in vitro via *** the exploration mechanism,we found ASH1L may promote an immunosuppressive mi

关键词： Hepatocellular carcinoma MicroRNA-142-3p ASH1L Immune evasion Tumor immune microenvironment Apoptosis

Characteristics of gut microbiota dysbiosis in patients with colorectal polyps

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 13-21页

作者： xian-Rong Wu Xiao-Hong He Yong-Fang Xie School of Life Health Information Science and Engineering Chongqing Post and Communications UniversityChongqing 400065China

This editorial,inspired by a recent study published in the World Journal of Gastrointestinal Oncology,covers the research findings on microbiota changes in various *** recurrent colorectal polyps,the abundances of Klebsiella,Parvimonas,and Clostridium increase,while those of Bifidobacterium and Lactoba-cillus *** dysbiosis may promote the formation and recurrence of *** microbial changes have also been observed in colorectal cancer,inflammatory bowel disease,autism spectrum disorder,and metabolic syndrome,indicating the role of increased pathogens and decreased probiotics in these *** the gut microbiota,particularly by increasing probiotic levels,may help prevent polyp recurrence and promote gut *** microbial intervention strategy holds promise as an adjunctive treatment for patients with colorectal polyps.

关键词： Recurrent colorectal polyps Gut microbiota dysbiosis Klebsiella Probiotics Intestinal inflammation Microbial intervention strategy

miR-15b-5p targeting amyloid precursor protein is involved in the anti-amyloid eflect of curcumin in swAPP695-HEK293 cells

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Neural Regeneration Research 2019年第9期14卷 1603-1609页

作者： Hong-ying Liu xian Fu You-Fu Li xian-Liang Li Zhen-Yu Ma ying Zhang Qing-chun Gao Department of Neurology the Second Affiliated Hospital of Guangzhou Medical University

Curcumin exerts a neuroprotective effect on Alzheimer’s disease;however,it is not known whether microRNAs are involved in this protective *** study was conducted using swAPP695-HEK293 cells as an Alzheimer’s disease cell ***695-HEK293 cells were treated with 0,0.5,1,2,5,and 10μM curcumin for 24 *** changes in miR-15b-5p,miR-19a-3p,miR-195-5p,miR-101-3p,miR-216b-5p,miR-16-5p and miR-185-5p expression were assessed by real-time quantitative polymerase chain *** mRNA and protein levels of amyloid precursor protein,amyloid-β40 and amyloid-β42 were evaluated by quantitative real-time polymerase chain reaction,western blot assays and enzyme-linked immunosorbent ***695-HEK293 cells were transfected with miR-15b-5p mimic,or treated with 1μM curcumin 24 hours before miR-15b-5p inhibitor *** effects of curcumin on amyloid precursor protein,amyloid-β40 and amyloid-β42 levels were evaluated by western blot assays and enzyme-linked immunosorbent *** assays were used to analyze the interaction between miR-15b-5p and the 3′-untranslated region of amyloid precursor *** results show that amyloid precursor protein and amyloid-βexpression were enhanced in swAPP695-HEK293 cells compared with HEK293 parental *** suppressed the expression of amyloid precursor protein and amyloid-βand up-regulated the expression of miR-15b-5p in swAPP695-HEK293 *** addition,we found a negative association of miR-15b-5p expression with amyloid precursor protein and amyloid-βlevels in the curcumin-treated *** assays revealed that miR-15b-5p impaired the luciferase activity of the plasmid harboring the 3′-untranslated region of amyloid precursor *** findings indicate that curcumin down-regulates the expression of amyloid precursor protein and amyloid-βin swAPP695-HEK293 cells,which was partially mediated by miR-15b-5p via targeting of the 3′-untranslated region of amyloid precursor protein.

关键词： nerve regeneration Alzheimer’s disease natural plant drug curcuminoids miRNAs amyloid precursor protein amyloid-β 3′-untranslated region Luciferase assays neurons neural regeneration

Dual-domain and Multiscale Fusion Deep Neural Network for PPG Biometric Recognition

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Machine Intelligence Research 2023年第5期20卷 707-715页

作者： chun-ying Liu Gong-Ping Yang Yu-Wen Huang Fu-xian Huang School of computer Heze UniversityHeze 274015China School of Software Shandong UniversityJinan 250101China

Photoplethysmography(PPG)biometrics have received considerable *** deep learning has achieved good performance for PPG biometrics,several challenges remain open:1)How to effectively extract the feature fusion representation from time and frequency PPG signals.2)How to effectively capture a series of PPG signal transition information.3)How to extract timevarying information from one-dimensional time-frequency sequential *** address these challenges,we propose a dual-domain and multiscale fusion deep neural network(DMFDNN)for PPG biometric *** DMFDNN is mainly composed of a two-branch deep learning framework for PPG biometrics,which can learn the time-varying and multiscale discriminative features from the time and frequency ***,we design a multiscale extraction module to capture transition information,which consists of multiple convolution layers with different receptive fields for capturing multiscale transition *** addition,the dual-domain attention module is proposed to strengthen the domain of greater contributions from time-domain and frequency-domain data for PPG *** on the four datasets demonstrate that DMFDNN outperforms the state-of-the-art methods for PPG biometrics.

关键词： Photoplethysmography(PPG)signal biometric recognition multiple scale deep neural network dual-domain attention.