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Fluid-solid coupling numerical simulation of micro-disturbance grouting treatment for excessive deformation of shield tunnel

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Underground Space 2024年第6期19卷 87-100页

作者： Yanjie Zhang Zheng Cao chun liu Hongwei Huang College of Civil Engineering and Architecture Henan University of TechnologyZhengzhou 450001China School of Earth Sciences and Engineering Nanjing UniversityNanjing 210023China Key Laboratory of Geotechnical and Underground Engineering of Ministry of Education Tongji UniversityShanghai 200092China Department of Geotechnical Engineering College of Civil EngineeringTongji UniversityShanghai 200092China

Micro-disturbance grouting is a recovery technique to reduce the excessive deformation of operational shield tunnels in urban *** grout mass behaves as a fluid in the ground before hardening to form a grout–soil mixture,which highlights the necessity of using fluid–solid coupling method in the simulation of grouting *** a discrete element modeling environment,this paper proposes a novel fluid-solid coupling method based on the pore density flow *** demonstrate the effectiveness of this method,it is applied to numerical simulation of micro-disturbance grouting process for treatment of large transverse deformation of a shield tunnel in Shanghai Metro,*** simulation results reveal the mechanism of recovering tunnel convergence by micro-disturbance grouting in terms of compaction and fracture of soil,energy analysis during grouting,and mechanical response of soil-tunnel interaction ***,the influence of the three main grouting parameters(i.e.,grouting pressure,grouting distance,and grouting height)on tunnel deformation recovery efficiency is evaluated through parametric *** order to efficiently recover large transverse deformation of shield tunnel in Shanghai Metro,it is suggested that the grouting pressure should be about 0.55 MPa,the grouting height should be in the range of 6.2–7.0 m,and the grouting distance should be in the range of 3.0–3.6 *** results provide a valuable reference for grouting treatment projects of over-deformed shield tunnel in soft soil areas.

关键词： Fluid-solid coupling Discrete element method Pore density flow Micro-disturbance grouting Soil-tunnel interaction

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Relationship Between Short-chain Fatty Acids and Parkinson’s Disease:A Review from Pathology to Clinic

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Neuroscience Bulletin 2024年第4期40卷 500-516页

作者： Wen-Xiang Duan Fen Wang Jun-Yi liu chun-Feng liu Department of Neurology and Clinical Research Center of Neurological Disease The Second Affiliated Hospital of Soochow UniversitySuzhou215004China Department of Neurology Dushu Lake Hospital affiliated to Soochow UniversitySuzhou215125China Jiangsu Key Laboratory of Neuropsychiatric Diseases and Institute of Neuroscience Soochow UniversitySuzhou215123China

Parkinson’s disease(PD)is a complicated neurodegenerative disease,characterized by the accumulation ofα-synuclein(α-syn)in Lewy bodies and neurites,and massive loss of midbrain dopamine *** evidence suggests that gut microbiota and microbial metabolites are involved in the development of *** these,short-chain fatty acids(SCFAs),the most abundant microbial metabolites,have been proven to play a key role in brain-gut *** this review,we analyze the role of SCFAs in the pathology of PD from multiple dimensions and summarize the alterations of SCFAs in PD patients as well as their correlation with motor and non-motor *** research should focus on further elucidating the role of SCFAs in neuroinflammation,as well as developing novel strategies employing SCFAs and their derivatives to treat PD.

关键词： Parkinson’s disease Short-chain fatty acids Microbial metabolites Brain-gut-microbiota axis

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Anomalous response to creep deformation from dislocation density during electrically assisted creep aging

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Rare Metals 2024年第10期43卷 5268-5283页

作者： Chang Zhou Li-Hua Zhan chun-Hui liu Ming-Hui Huang College of Mechanical and Electrical Engineering Central South University Light Alloys Research Institute State Key Laboratory of Precision Manufacturing for Extreme Service PerformanceCentral South University

Adding numerous dislocations into metallic materials before the forming stage significantly enhances their deformability. However, this beneficial effect of dislocation defects may not have a simple monotonic relationship with increased dislocation density during electroplastic deformation. This is due to the complex interactions among the drifting electrons, dislocations and solute atoms. This study explores the effect of diverse initial dislocation densities on creep deformation during electrically aided creep aging of an aluminum–lithium alloy. Surprisingly, we discovered a threshold value for the dislocation density that affects electroplastic creep, i.e., an enhanced effect from dislocations weakens when exceeding this density threshold(an anomalous response to creep). Microstructural data also reveal that such an anomalous response originates mainly from differences in various dislocation density-tailored configurations, which can influence the dislocation motions and precipitation kinetics of the strengthening T1precipitates under the same action of pulsed currents. This study provides important insights into the dislocation density-mediated electroplastic creep of an aluminum–lithium alloy.

关键词： Al–Cu–Li alloy Creep aging Dislocation density Pulsed currents

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Systematic bibliometric and visualized analysis of research hotspots and trends on the application of artificial intelligence in glaucoma from 2013 to 2022

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International Journal of Ophthalmology(English edition) 2024年第9期17卷 1731-1742页

作者： chun liu Lu-Yao Wang Ke-Yu Zhu chun-Meng liu Jun-Guo Duan Eye School of Chengdu University of TCM Chengdu 610072Sichuan ProvinceChina Ineye Hospital of Chengdu University of TCM Chengdu 610084Sichuan ProvinceChina Key Laboratory of Sichuan Province Ophthalmopathy Prevention&Cure and Visual Function Protection with TCM Laboratory Chengdu 610072Sichuan ProvinceChina

AIM:To conduct a bibliometric analysis of research on artificial intelligence(AI)in the field of glaucoma to gain a comprehensive understanding of the current state of research and identify potential new directions for future ***:Relevant articles on the application of AI in the field of glaucoma from the Web of Science Core Collection were retrieved,covering the period from January 1,2013,to December 31,*** order to assess the contributions and co-occurrence relationships among different countries/regions,institutions,authors,and journals,CiteSpace and VOSviewer software were employed and the research hotspots and future trends within the field were ***:A total of 750 English articles published between 2013 and 2022 were collected,and the number of publications exhibited an overall increasing *** majority of the articles were from China,followed by the United States and *** University of Singapore,Chinese Academy of Sciences,and Sun Yat-sen University made significant contributions to the published *** RN and Fu HZ ranked first among authors and cited *** Journal of Ophthalmology is the most impactful academic journal in the field of AI application in *** disciplinary scope of this field includes ophthalmology,computer science,mathematics,molecular biology,genetics,and other related *** clustering and identification of keyword nodes in the co-occurrence network reveal the evolving landscape of AI application in the field of ***,the hot topics in this field were primarily“segmentation”,“classification”and“diagnosis”.However,in recent years,the focus has shifted to“deep learning”,“convolutional neural network”and“artificial intelligence”.CONCLUSION:With the rapid development of AI technology,scholars have shown increasing interest in its application in the field of ***,the application of AI in assisting treatment and predicting prognosis in glaucom

关键词： glaucoma ar tificial intelligence bibliometrics

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Problem identification and revitalization strategies for the recovery and reconstruction of traditional villages in the Ms 6.8 Luding Earthquake

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Journal of Mountain Science 2024年第2期21卷 361-379页

作者： HUANG Chao QIU Jian liu chun JIANG Rui ZHAO Chuanrong ZHANG Yi School of Architecture and Research Center of Space Planning and Engineering Design Southwest Jiaotong UniversityChengdu 611756China Sichuan Provincial Rural Construction and Development Center Chengdu 610041China Sichuan Institute of Urban and Rural Construction Chengdu 610043China China Association for Promoting Democracy(CAPD)Sichuan Provincial Committee Chengdu 610016China Sichuan Provincial Architectural Design and Research Institute(SADI) Chengdu 610095China

Post-disaster reconstruction is a topic of global concern,and traditional villages have special heritage attributes and need to face more requirements and obstacles in post-disaster *** paper summarizes four concepts based on the research on post-disaster reconstruction both domestically and internationally,as well as the recovery and reconstruction of cultural *** a field survey of traditional villages in the Ms 6.8 Luding earthquake-stricken area,it is found that there are problems such as insufficient awareness of heritage value,misalignment of scientific reconstruction technology,and insufficient protection of reconstruction elements during the reconstruction *** villages face the risk of declining or even loss of heritage *** order to effectively protect traditional villages and inherit the carrier of regional culture,four targeted reconstruction response strategies are proposed,i.e.,to"establish special planning for traditional village preservation","emphasize recovery of the authenticity of village heritage","ensure elements for village heritage recovery"and"promote the activation and utilization of village heritage",based on the problems discovered during the survey and the four concepts summarized in the research on post-disaster reconstruction of traditional *** research results hope to provide useful reference for ancient cultural areas affected by earthquakes on how to protect cultural heritage during the post-disaster reconstruction process.

关键词： Seismic hazard Decision making Traditional village Cultural heritage protection Post-earthquake recovery and reconstruction Revitalization strategy

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Double-confined nanoheterostructure Sb/Sb_(2)S_(3)@Ti_(3)C_(2)T_(x)@C toward ultra-stable Li-/Na-ion batteries

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Rare Metals 2024年第5期43卷 2067-2079页

作者： Dan Wang Qun Ma Huan He Zhi-Yuan Wang Run-Guo Zheng Hong-Yu Sun Yan-Guo liu chun-Li liu School of Materials Science and Engineering Northeastern UniversityShenyang110819China School of Resources and Materials Northeastern University at QinhuangdaoQinhuangdao 066004China Key Laboratory of Dielectric and Electrolyte Functional Material Hebei Province Qinhuangdao 066004China Department of Physics and Oxide Research Center Hankuk University of Foreign StudiesYongin 17035Korea

Antimony-based materials with high capacities and moderate potentials are promising anodes for lithium-/-sodium-ion ***,their tremendous volume expansion and inferior conductivity lead to poor structural stability and sluggish reaction ***,a doubleconfined nanoheterostructure Sb/Sb_(2)S_(3)@Ti_(3)C_(2)T_(x)@C has been fabricated through a solvothermal method followed by low-temperature heat *** dual protection of“MXene”and“carbon”can better accommodate the volume expansion of Sb/Sb_(2)S_(3).The strong covalent bond(Ti-S,Ti-O-Sb,C-O-Sb)can firmly integrate Sb-based material with Ti_(3)C_(2)T_(x)and carbon,which significantly improves the structure *** addition,the carbon layer can restrain the oxidation of MXenes,and the nano-Sb/Sb_(2)S_(3)can facilitate electron/ion transport and suppress the restacking of *** heterogeneous interface between Sb and Sb_(2)S_(3)can further promote interfacial charge *** MXene-Sb/Sb_(2)S_(3)@C-1 with the optimal Sb content shows high specific capacities,comparable rate properties and ultra-stable cycling performances(250 m Ah·g^(-1)after 2500 cycles at 1 A·g^(-1)for sodium-ion batteries).Ex situ X-ray diffractometer(XRD)test reveals the storage mechanism including the conversion and alloying process of MXene-Sb/Sb_(2)S_(3)@*** voltammetry(CV)test results demonstrate that the pseudocapacitance behavior is dominant in MXene-Sb/Sb_(2)S_(3)@C-1,especially at large *** design paves the way for exploring high-performance alloy-based/conversion-type anode for energy storage devices.

关键词： Sb/Sb_(2)S_(3) MXene Carbon Anode Lithium-ion batteries Sodium-ion batteries

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Prediction model on hydrolysis kinetics of phthalate monoester:A density functional theory study

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Journal of Environmental Sciences 2024年第1期135卷 51-58页

作者： Tong Xu Jingwen Chen Deming Xia Weihao Tang Jiansheng Cui chun liu Shuangjiang Li College of Environmental Science and Engineering Hebei University of Science and TechnologyShijiazhuang 050000China Key Laboratory of Industrial Ecology and Environmental Engineering(Ministry of Education) School of Environmental Science and TechnologyDalian University of TechnologyDalian 116024China National-Regional Joint Engineering Research Center for Soil Pollution Control and Remediation in South China Guangdong Key Laboratory of Integrated Agro-environmental Pollution Control and ManagementInstitute of Eco-environmental and Soil SciencesGuangdong Academy of SciencesGuangzhou 510650China

As primary degradation products of phthalate esters,phthalate monoesters(MPEs)have been widely detected in various aquatic environments and drawn growing toxicological *** kinetics that is of importance for assessing environmental persistence of chemicals remain elusive for ***,kinetics of base-catalyzed and neutral hydrolysis for 18 MPEs with different leaving groups was investigated by density functional theory *** indicate that MPEs with leaving groups having p Kaof<10 prefer dissociative transition *** are more persistent than their parents,and their hydrolysis half-lives were calculated to vary from 3.4 min to 79.2 years(p H=7–9).A quantitative structure-activity relationship model was developed for predicting the hydrolysis kinetics *** was found that p Kaof the leaving groups and electronegativity of the MPEs are key factors determining the hydrolysis *** work may lay a theoretical foundation for better understanding the chemical process that governs MPE persistence in aquatic environments.

关键词： Phthalate monoesters Phthalate esters Hydrolysis Density functional theory Quantitative structure-activity relationship

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Combined strategies for improving the heterologous expression of a novel xylanase from Fusarium oxysporum Fo47 in Pichia pastoris

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Synthetic and Systems Biotechnology 2024年第3期9卷 426-435页

作者： chun liu Yaping Zhang chunting Ye Fengguang Zhao Yian Chen Shuangyan Han School of Biology and Biological Engineering South China University of TechnologyGuangzhou510640China School of Light Industry and Engineering South China University of TechnologyGuangzhou510640China

Xylanase,an enzyme capable of hydrolyzing non-starch polysaccharides found in grain structures like wheat,has been found to improve the organizational structure of dough and thus increase its *** our past work,one promising xylanase FXYL derived from Fusarium oxysporum Fo47 and first expressed 779.64 U/mL activity in *** has shown significant potential in improving the quality of whole wheat bread,making it become a candidate for development as a new flour *** optimization of expression elements and gene dose,the xylanase activity of FXYL strain carrying three-copies reached 4240.92 U/mL in *** addition,12 factors associated with the three stages of protein expression pathway were co-expressed individually in order in three-copies strain,and the translation factor Pab1 co-expression increased FXYL activity to 8893.53 U/***,combining the most effective or synergistic factors from three stages did not exhibit better results than co-expressing them *** further evaluate the industrial potential,the xylanase activity and protein concentration reached 81184.51 U/mL and 11.8 g/L in a 5 L fed-batch *** engineering strategies improved the expression of xylanase FXYL by more than 104-fold,providing valuable insights for the cost-effective industrial application of FXYL in the baking field.

关键词： Xylanase Pichia pastoris Heterologous protein Secretion expression

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Aggressive fibromatosis of the sigmoid colon:A case report

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World Journal of Gastrointestinal Oncology 2024年第8期16卷 3716-3722页

作者： Pan-Pan Yu Xin-chun liu Lu Yin Guang Yin Department of Gastrointestinal and Anal Surgery The Affiliated Hangzhou First People's HospitalSchool of MedicineWestlake UniversityHangzhou 310006Zhejiang ProvinceChina Department of Gastric Surgery Zhejiang Cancer HospitalHangzhou 310022Zhejiang ProvinceChina Department of Pathology The Affiliated Hangzhou First People's HospitalSchool of MedicineWestlake UniversityHangzhou 310006Zhejiang ProvinceChina

BACKGROUND Aggressive fibromatosis(AF),also known as desmoid tumor or desmoid-type fibromatosis,is a rare soft tissue neoplasm that can occur in almost any part of the *** it is a benign disease,AF is aggressive and infiltrative and has a high recurrence rate after *** sites for intra-abdominal AF are the small bowel mesentery,retroperitoneum,and *** in the colon is extremely *** SUMMARY Here,we report the first case of sigmoid colon AF,which was accidentally discovered in a 27-year-old woman during laparoscopic *** tomography confirmed a slightly enhanced mass in the sigmoid *** colonoscopy did not reveal a mass in the colonic lumen,but a suspected external compress was found in the sigmoid *** disease involving a gastrointestinal stromal tumor was *** patient underwent laparoscopic exploration,and sigmoidectomy with a negative margin was performed to excise the *** immunohistochemistry revealed that the mass was an *** patient recovered well and was recurrence-free at the 30-month follow-up without adjuvant *** AF should be considered in the differential diagnosis of subepithelial colon *** resection alone can achieve good outcomes.

关键词： Aggressive fibromatosis Desmoid tumor Sigmoid mass Subepithelial tumor Case report

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Enhanced Crystallization of Poly(butylene adipate-co-terephthalate)by a Self-assembly Nucleating Agent

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Chinese Journal of Polymer Science 2024年第5期42卷 663-674,I0010页

作者： Cheng Zhou Kun Chen Zi-Heng Zhang Meng-Fan Jing chun-Tai liu Chang-Yu Shen Ya-Ming Wang State Key Laboratory of Structural Analysis Optimization and CAE Software for Industrial EquipmentNational Engineering Research Center for Advanced Polymer Processing TechnologyZhengzhou UniversityZhengzhou450002China

Poly(butylene adipate-co-terephthalate)(PBAT)is a promising biodegradable flexible polymer but suffers from slow crystallization rate,making it less attractive for some applications like the injection-molded products in comparison with low-density polyethylene(LDPE).This work aimed to accelerate the crystallization of PBAT by adding a self-assembly nucleating agent octamethylenedicarboxylic dibenzoylhydrazide(OMBH).PBAT/OMBH composites with various OMBH contents(0 wt%,0.5 wt%,0.7 wt%,1 wt%,2 wt%,3 wt%and 5 wt%)were prepared through *** effect of OMBH on the crystallization behavior,morphologies and mechanical properties of PBAT was *** highest nucleation efficiency value of 59.6%was achieved for PBAT with 0.7 wt%OMBH,much higher than that of 22.7%for PBAT with 0.7 wt%*** force microscopy results showed that OMBH formed fine fibers and induced the formation of transcrystalline layers of *** transform infrared spectroscopy(FTIR)combined with two-dimensional correlation spectra suggested that the intermolecular dipole-dipole N—H…O=C interactions but not hydrogen bond between OMBH and PBAT promoted the crystallization of PBAT in the initial period of *** presence of OMBH did not change the crystal form of PBAT but had positive contribution in enhancing its crystallinity and mechanical *** work is essential for preparing PBAT with high crystallization rate,enhancing its potential applications in injection-molded products.

关键词： Poly(butylene adipate-co-terephthalate) Biodegradable Self-assembly nucleating agent Crystallization

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