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Enhanced thermoelectric properties of SnSe thin films grown by pulsed laser glancing-angle deposition

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Journal of Materiomics 2017年第4期3卷 293-298页

作者： chun hung suen Dongliang Shi Y.Su Zhi Zhang Cheuk Ho Chan Xiaodan Tang Y.Li Kwok Ho Lam Xinxin Chen B.L.Huang X.Y.Zhou Ji-Yan Dai Department of Applied Physics The Hong Kong Polytechnic UniversityHung HomKowloonHong KongChina Department of Electrical Engineering The Hong Kong Polytechnic UniversityHung HomKowloonHong KongChina Department of Mechanical and Aerospace Engineering The Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina College of Physics Chongqing UniversityChongqing 401331China

SnSe single crystals have been demonstrated to possess excellent thermoelectric *** this work,we demonstrate a grain size control method in growing nanocrystalline SnSe thin films through a glancing angle pulsed-laser deposition *** characterization reveals that the SnSe film deposited at a normal angle has a preferred orientation along a axis,while by contrast,the SnSe film deposited at an 80glancing angle develops a nanopillar structure with the growth direction towards the incident atomic *** glancing angle deposition greatly reduces the grain size of the thin film due to a shadowing effect to the adatoms,resulting in significantly increased power factor for more than 100%.The maximum Seebeck coefficient and power factor are 498.5 mV=K and 18.5 mWcm^(-1)K^(-2),*** enhancement of thermoelectric property can be attributed to the potential barrier scattering at grain boundaries owing to the reduced grain size and increased grain boundaries in the *** this enhanced power factor,and considering the fact that the nanopillar structure should have much lower thermal conductivity than a plain film,the zT value of such made SnSe film could be significantly larger than the corresponding single crystal film,making it a good candidate for thin film-based thermoelectric device.

关键词： Thermoelectric SnSe Glancing angle Potential barrier scattering

Community perspectives on the effectiveness of watershed management institutions in the Himalayas

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Journal of Mountain Science 2024年第4期21卷 1119-1139页

作者： Nisha SILWAL Nabin DhungANA Rajan SUBEDI Suraj UPADHAYA chun-hung LEE Natural Resources Conservation Nepal(NRCN) ChitwanP.O.Box 44200Nepal Department of Natural Resources and Environmental Studies College of Environmental StudiesNational Dong Hwa UniversityHualien 97401Chinese Taipei Institute of Forestry Tribhuvan UniversityPokharaP.O.Box 43Nepal School of Agriculture and Natural Resources Kentucky State UniversityFrankfortKY 40601USA Himalayan Conservation and Research Institute DolpaP.O.Box 21400Nepal

The sustainability of environmental management initiatives,such as watershed management programs,relies on the presence of effective institutions at the watershed ***,there needs to be more empirical evidence from evaluating the effectiveness of watershed-level ***,this study presents a pioneering effort to evaluate the effectiveness of Nepal’s first watershed conservation committee at the watershed scale,focusing on the case of the Khageri Khola watershed in Central *** study involved conducting a household survey,key informant interviews,focus group discussions,and field observations to collect and analyze the *** analysis,index value calculation,and chi-square statistics were then employed to summarize the results regarding local respondents’perceptions of twelve institutional characteristics,their rationalities,and their association with socio-demographic *** results reveal that the watershed conservation committee was perceived as performing well in managing the ***,good interaction,appropriate scale,technical,environmental,social,organizational,and government rationality were perceived as highly effective,with an average index value of less than *** contrast,clarity of objectives and economic rationality showed moderate effectiveness,with an average index value ranging from 0.36 to ***,the results suggested that adaptiveness,compliance capacity,and financial rationality merit increased attention,intending to improve their ***,the results showed the association of socio-demographics with respondents’perceptions of various indicators of institutional characteristics and their ***,the study provides valuable insights for policymakers,researchers,and development practitioners charged with designing sustainable and effective programs and *** enhance the effectiveness and sustainability of watershed management programs,we recommen

关键词： Watershed Watershed institutions Indicators Institutional characteristics Rationalities Nepal.

IgG4 Coronary Arteritis Presenting as a Cardiac Pseudo-Tumour

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Case Reports in Clinical Medicine 2024年第9期13卷 345-352页

作者： Elaine Mo-Chee Chau Catherine Yuet-hung Wong Raymond Hin-suen Liang Cardiology Centre Hong Kong Sanatorium & Hospital Hong Kong SAR China Nuclear Medicine Department Hong Kong Sanatorium & Hospital Hong Kong SAR China Comprehensive Oncology Centre Hong Kong Sanatorium & Hospital Hong Kong SAR China

We report on an unusual case presenting with a cardiac pseudo-tumour on echocardiogram, which corresponded to a large soft tissue mural thickening around the mid-right coronary artery. There were similar but not as thick mural lesions around other parts of the coronary arteries. The so-called “pigs-in-a-blanket” sign on computed tomography (CT) scan was pathognomonic of IgG4 coronary arteritis. The IgG4 level was grossly elevated at more than 10 times the upper limit of normal. Positron emission tomography (PET)-CT scans with 18F-fluoro-deoxy-glucose (FDG) and 68Ga-Fibroblast Activation Protein Inhibitor (FAPI) were performed to assess the extent of organ involvement of the IgG4-related disease. The patient was treated with 8 injections of rituximab with good serological response. However, the coronary arteritis findings on CT scan remained unchanged.

关键词： IgG4-Related Disease Coronary Arteritis Cardiac Pseudo-Tumour “Pigs-in-a-Blanket” Sign

Stercoral perforation of the cecum:A case report

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World Journal of Gastrointestinal Surgery 2024年第4期16卷 1189-1194页

作者： hung-chun Yu Ta-Wei Pu Jung-Cheng Kang Chao-Yang Chen Je-Ming Hu Ruei-Yu Su Department of Surgery Taichung Armed Forces General HospitalTaichung 411228Taiwan Department of Surgery Tri-Service General HospitalNational Defense Medical CenterTaipei 11490Taiwan Division of Colon and Rectal Surgery Department of SurgeryTri-Service General Hospital Songshan BranchNational Defense Medical CenterTaipei 105Taiwan Division of Colon and Rectal Surgery Department of SurgeryTaiwan Adventist HospitalTaipei 105Taiwan Division of Colon and Rectal Surgery Department of SurgeryTri-Service General HospitalNational Defense Medical CenterTaipei 114Taiwan Department of Pathology Tri-Service General HospitalNational Defense Medical CenterTaipei 105Taiwan Department of Pathology and Laboratory Medicine Taoyuan Armed Forces General HospitalTaoyuan 325Taiwan

BACKGROUND With less than 90 reported cases to date,stercoral perforation of the colon is a rare *** ulceration is thought to occur due to ischemic pressure necrosis of the bowel wall,which is caused by the presence of a stercoraceous *** underscore this urgent surgical situation concerning clinical presentation,surgical treatment,and results,we present the case of a 66-year-old man with a stercoral *** SUMMARY A 66-year-old man with a history of hypertension,hyperlipidemia,and gout presented at the emergency department with lower abdominal pain and a low-grade fever lasting for a few *** computed tomography indicated a suspected bezoar(approximately 7.6 cm)in the dilated cecum,accompanied by pericolic fat stranding,mild proximal dilatation of the ileum,pneumoperitoneum,and minimal ***,feculent peritonitis with isolated cecal perforation were ***,a right hemicolectomy with peritoneal lavage was performed.A histopathological examination supported the intraoperative *** In stercoral perforations,a diagnosis should be diligently pursued,especially in older adults,and prompt surgical intervention should be implemented.

关键词： Acute abdomen Colectomy Peritoneal lavage Pneumoperitoneum Bezoars Case report

Re-evaluating the role of pelvic radiation in the age of modern precision medicine and systemic therapy

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World Journal of Clinical Oncology 2024年第1期15卷 1-4页

作者： Tao-Wei Ke Yu-Min Liao Sheng-Chi Chang Che-hung Lin William Tzu-Liang Chen Ji-An Liang chun-Ru Chien Department of Colorectal Surgery China Medical University HospitalTaichung 40402Taiwan School of Chinese Medicine College of Chinese MedicineChina Medical UniversityTaichung 40402Taiwan Division of Hematology and Oncology Department of Internal MedicineChina Medical University HospitalTaichung 40402Taiwan Department of Colorectal Surgery China Medical University Hsinchu HospitalHsinchu 30272Taiwan School of Medicine College of MedicineChina Medical UniversityTaichung 40402Taiwan Department of Radiation Oncology China Medical University HospitalTaichung 40402Taiwan

The efficacy of pelvic radiation in the management of locally advanced stage rectal cancer has come under scrutiny in the context of modern precision medicine and systemic therapy as evidenced by recent clinical trials such as FOWARC(J Clin Oncol 2019;37:3223-3233),NCT04165772(N Engl J Med 2022;386:2363-2376),and PROSPECT(N Engl J Med 2023;389:322-334).In this review,we comprehensively assess these pivotal trials and offer additional insights into the evolving role of pelvic radiation in contemporary oncology.

关键词： Radiotherapy Locally advanced stage rectal cancer Precision medicine Systemic therapy Clinical trial

Landslide Susceptibility Mapping by Using Landslide RatioBased Logistic Regression:A Case Study in the Southern Taiwan

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Journal of Mountain Science 2015年第3期12卷 721-736页

作者： WU chun-hung Department of Water Resources Engineering and Conservation Feng Chia University

The object of the research is to compare the model performance and explain the error source of original logistic regression landslide susceptibility model(abbreviated as or-LRLSM) and landslide ratio-based logistic regression landslide susceptibility model(abbreviated as lr-LRLSM) in the Chishan watershed with a serious landslide disaster after 2009 Typhoon Morakot. The landslide inventory induced by 2009 Typhoon Morakot in South Taiwan is the main research material, while the Chishan watershed is the research area. Six variables, including elevation, slope, aspect, geological formation, accumulated rainfall, and bank erosion, were included in the two models. The performance of lr-LRLSM is better than that of or-LRLSM. The Cox & Snell R2, Nagelkerke R2 value, and the area under the relative operating characteristic curve(abbreviated as AUC) of lrLRLSM is larger than those of or-LRLSM, and the average correct ratio for the lr-LRLSM to predict landslide or non-landslide is larger than that of orLRLSM by 5.0%. The increase of the average correct ratio(abbreviated as ACR) difference from or-LRLSM to lr-LRLSM shows in slope, revised accumulated rainfall, aspect, geological formation and bank erosion variables, and only light decreases in elevation variable. The error sources of continuous variables in building the or-LRLSM is the dissimilarity between the distribution of landslide ratio and production of coefficient and characteristic values, while those of categorical variables is due to low correlation of landslide ratio and the coefficient value of each parameter. Using the classification of landslide ratio as the database to build logistic regression landslide susceptibility model(abbreviated as LRLSM) can revise the errors. The comparison of or-LRLSM and lr-LRLSM in the Chishan watershed also shows that building the landslide susceptibility model(abbreviated as LSM) by using lr-LRLSM is practical and of better performance than that by using the or-LRLSM.

关键词： Logistic regression Landslidesusceptibility Landslide ratio Chishan watershed Typhoon Morakot

Acute-on-chronic liver failure：recent update

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The Journal of Biomedical Research 2017年第4期31卷 283-300页

作者： Azeem Alam Ka chun suen Daqing Ma Anaesthetics Pain Medicine and Intensive Care Department of Surgery and Cancer Faculty of Medicine Imperial College London Chelsea & Westminster Hospital London SW7 2AZ UK

Acute on chronic liver failure（ACLF） was first described in 1995 as a clinical syndrome distinct to classic acute *** by complications of decompensation,ACLF occurs on a background of chronic liver dysfunction and is associated with high rates of organ failure and significant short-term mortality estimated between45%and 90%.Despite the clinical relevance of the condition,it still remains largely undefined with continued disagreement regarding its precise etiological factors,clinical course,prognostic criteria and management *** is concerning that,despite our relative lack of understanding of the condition,the burden of ACLF among cirrhotic patients remains significant with an estimated prevalence of 30.9%.This paper highlights our current understanding of ACLF,including its etiology,diagnostic and prognostic criteria and *** is evident that further refinement of the ACLF classification system is required in order to detect high-risk patients and improve short-term mortality *** field of metabolomics certainly warrants investigation to enhance diagnostic and prognostic parameters,while the use of granulocyte-colony stimulating factor is a promising future therapeutic intervention for patients with ACLF.

关键词： acute liver failure acute decompensation of cirrhosis hepatorenal syndrome chronic hepatic encephalopathy systemic inflammation

lahysiological links of circadian clock and biological clock of aging

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Protein & Cell 2017年第7期8卷 477-488页

作者： Fang Liu hung-chun Chang Institute of Neuroscience State Key Laboratory of Neuroscience Key Laboratory of Primate Neurobiology CAS Center for Excellence in Brain Science and Intelligence Technology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Shanghai 200031 China University of Chinese Academy of Sciences Shanghai 200031 China

Circadian rhythms orchestrate biochemical and physi-ological processes in living organisms to respond the day/night cycle. In mammals, nearly all cells hold self- sustained circadian clocks meanwhile couple the intrinsic rhythms to systemic changes in a hierarchical manner. The suprachiasmatic nucleus （SCN） of the hypothalamus functions as the master pacemaker to initiate daily synchronization according to the photope-riod, in turn determines the phase of peripheral cellular clocks through a variety of signaling relays, including endocrine rhythms and metabolic cycles. With aging, circadian desynchrony occurs at the expense of peripheral metabolic pathologies and central neurode- generative disorders with sleep symptoms, and genetic ablation of circadian genes in model organisms resem- bled the aging-related features. Notably, a number of studies have linked longevity nutrient sensing pathways in modulating circadian clocks. Therapeutic strategies that bridge the nutrient sensing pathways and circadian clock might be rational designs to defy aging.

关键词： circadian rhythms SCN longevity

Perioperative"remote"acute lung injury:recent update

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The Journal of Biomedical Research 2017年第3期31卷 197-212页

作者： Zhaosheng Jin Ka chun suen Daqing Ma Anaesthetics Pain Medicine and intensive CareDepartment of Surgery and CancerFaculty of MedicineImperial College LondonChelsea&Westminster HospitalLondon SW10 9NHUK

Perioperative acute lung injury（ALI） is a syndrome characterised by hypoxia and chest radiograph *** is a serious post-operative complication,associated with considerable mortality and *** addition to mechanical ventilation,remote organ insult could also trigger systemic responses which induce ***,there are limited treatment options available beyond conservative respiratory ***,increasing understanding of the pathophysiology of ALI and the biochemical pathways involved will aid the development of novel treatments and help to improve patient outcome as well as to reduce cost to the health *** this review we will discuss the epidemiology of peri-operative ALI;the cellular and molecular mechanisms involved on the pathological process;the clinical considerations in preventing and managing perioperative ALI and the potential future treatment options.

关键词： acute lung injury intraoperative care/adverse effects postoperative complications inflammation,anesthetics general fluid therapy