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Chinese Physics B 2022年第5期31卷 683-690页

作者： Fengling Chen Jiannan Lin Yifan Chen Binbin Dong chujun yin Siying Tian Dapeng Sun Jing Xie Zhenyu Zhang Hong Li Chaobo Li Institute of Microelectronics Chinese Academy of SciencesBeiing 100029China University of Chinese Academy of Sciences Beijing 100049China Institute of Physics Chinese Academy of SciencesBeijing 100190China Beijing Welion New Energy Technology Co. LtdBeijing 102402China

Nickel-rich cathode materials are increasingly being applied in commercial lithium-ion batteries to realize higher specific capacity as well as improved energy ***,low structural stability and rapid capacity decay at high voltage and temperature hinder their rapid large-scale ***,a wet chemical method followed by a post-annealing process is utilized to realize the surface coating of tantalum oxide on LiNi_(0.88)Mn_(0.03)Co_(0.09)O_(2),and the electrochemical performance is *** modified Li Ni_(0.88)Mn_(0.03)Co_(0.09)O_(2)displays an initial discharge capacity of~233 m Ah/g at0.1 C and 174 m Ah/g at 1 C after 150 cycles in the voltage range of 3.0 V–4.4 V at 45℃,and it also exhibits an enhanced rate capability with 118 m Ah/g at 5 *** excellent performance is due to the introduction of tantalum oxide as a stable and functional layer to protect the surface of LiNi_(0.88)Mn_(0.03)Co_(0.09)O_(2),and the surface side reactions and cation mixing are suppressed at the same time without hampering the charge transfer kinetics.

关键词： LiNi0.88Mn0.03Co0.09O2 tantalum oxide surface coating lithium-ion battery cathode material

Probing the improved stability for high nickel cathode via dual-element modification in lithium-ion

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Chinese Physics B 2022年第7期31卷 586-594页

作者： Fengling Chen Chaozhi Zeng Chun Huang Jiannan Lin Yifan Chen Binbin Dong chujun yin Siying Tian Dapeng Sun Zhenyu Zhang Hong Li Chaobo Li Institute of Microelectronics Chinese Academy of SciencesBeijing 100029China University of Chinese Academy of Sciences Beijing 100049China Shanghai Advanced Research Institute Chinese Academy of SciencesShanghai 201210China Beijing Welion New Energy Technology Co. LtdBeijing 102402China Institute of Physics Chinese Academy of SciencesBeijing 100190China

One of the major hurdles of nickel-rich cathode materials for lithium-ion batteries is the low cycling stability,especially at high temperature and high voltage,originating from severe structural degradation,which makes this class of cathode less ***,we compared the effect of single and dual ions on electrochemical performance of high nickel(LiNi_(0.88)Mn_(0.03)Co_(0.09)O_(2),NMC)cathode material in different temperatures and voltage *** addition of a few amounts of tantalum(0.2 wt%)and boron(0.05 wt%)lead to improved electrochemical *** co-modified Li Ni_(0.88)Mn_(0.03)Co_(0.09)O_(2)displays an initial discharge capacity of 234.9 m Ah/g at 0.1 C and retained 208 m Ah/g at 1 C after 100 cycles at 45℃,which corresponds to a capacity retention of 88.5%,compared to the initial discharge capacity of234.1 m Ah/g and retained capacity of 200.5 m Ah/g(85.6%).The enhanced capacity retention is attributed to the synergetic effect of foreign elements by acting as a surface structural stabilizer without sacrificing specific capacity.

关键词： LiNi_(0.88)Mn_(0.03)Co_(0.09)O_(2) lithium-ion battery cathode material modification

Tannic acid assisted anti-TNF-αnanobody assembly modulating the epithelial barrier dysregulation of allergic rhinitis

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Nano Research 2023年第7期16卷 9781-9791页

作者： Shuilian Fu Zhiting Cao Baolian Huang Te yin chujun Huang Zhiqian Bi yingying Yao Xiaoyao Chang Hongqin Zhuang Zi-Chun Hua The State Key Laboratory of Pharmaceutical Biotechnology College of Life SciencesNanjing UniversityNanjing 210023China Changzhou High-Tech Research Institute of Nanjing University and Jiangsu TargetPharma Laboratories Inc. Changzhou 213164China School of Biopharmacy China Pharmaceutical UniversityNanjing 211198China

The derailed nasal epithelial barrier is associated with the disorder of tight junctions(TJ)function or expression,leading to more penetration of allergens to the barrier,accompanied by the release of cytokines,which develop allergic rhinitis(AR).Considering the increasing AR disease incidence worldwide,there is still an urgent unmet medical need to develop new *** necrosis factor-alpha(TNF-α)inhibitors have been applied in treating autoimmune ***,their roles in AR remain *** this study,anti-TNF-αnanobody(V)was assembled with tannic acid(V/TA)as a functional antibody drug candidate which could inhibit the release of the cytokines in ovalbumin(OVA)-induced AR murine *** receiving V/TA treatment,the infiltration level of inflammatory cells,and the number of mucus-secreting cells and mast cells in the nasal mucosa recovered to a relatively normal *** mechanism of action research revealed that the efficacy of V/TA was accompanied by the restricted level of TJ molecules:zonula occluden-1(ZO-1),occludin,claudin-1,and *** therapeutic effect of the anti-TNF-αnanobody against AR was enhanced with the tannic acid assisted without any toxicity *** study supplied a promising delivery strategy of TNF-αinhibitor for the effective treatment of complicated allergic rhinitis disease,with an advantage in restoring effect on the AR-caused epithelial barrier defects than the commercial drug Infliximab.

关键词： allergic rhinitis tumor necrosis factor-alpha(TNF-α)nanobody nanoparticles epithelial permeability tight junctions

ADAR1 Inhibits Macrophage Apoptosis and Alleviates Sepsis-induced Liver Injury Through miR-122/BCL2A1 Signaling

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Journal of Clinical and Translational Hepatology 2024年第2期12卷 134-150页

作者： Shanshou Liu Jiangang Xie chujun Duan Xiaojun Zhao Zhusheng Feng Zheng Dai Xu Luo Yu Li Minghe Yang Ran Zhuang Junjie Li Wen yin Emergency Department Xijing HospitalFourth Military Medical UniversityXi’anShaanxiChina Emergency Department Tangdu HospitalFourth Military Medical UniversityXi’anShaanxiChina Third Student Brigade School of Basic Medical ScienceFourth Military Medical UniversityXi’anShaanxiChina Department of Immunology Fourth Military Medical UniversityXi’anShaanxiChina

apoptosis plays regulatory roles in the pathogenesis of immunosuppression and organ *** previously reported that adenosine deaminases acting on RNA-1(ADAR1)reduced intestinal and splenic inflammatory damage during ***,the roles and mechanism of ADAR1 in sepsis-induced liver injury remain ***:We performed transcriptome and single-cell RNA sequencing of peripheral blood mononuclear cells(PBMCs)from patients with sepsis to investigate the effects of ADAR1 on immune cell *** also employed a cecal ligation and puncture(CLP)sepsis mouse model to evaluate the roles of ADAR1 in sepsisinduced liver ***,we treated murine RAW 264.7 macrophages with lipopolysaccharide to explore the underlying ADAR1-mediated mechanisms in ***:PBMCs from patients with sepsis had obvious apoptotic morphological ***-cell RNA sequencing indicated that apoptosis-related pathways were enriched in monocytes,with significantly elevated ADAR1 and BCL2A1 expression in severe ***-induced septic mice had aggravated liver injury and Kupffer cell apoptosis that were largely alleviated by ADAR1 ***1 directly bound to premiR-122 to modulate miR-122 ***-122 was an upstream regulator of ***,ADAR1 also reduced macrophage apoptosis in mice with CLP-induced sepsis through the miR-122/BCL2A1 signaling pathway and protected against sepsis-induced liver ***:The findings show that ADAR1 alleviates macrophage apoptosis and sepsis-induced liver damage through the miR-122/BCL2A1 signaling *** study provides novel insights into the development of therapeutic interventions in sepsis.

关键词： Sepsis Macrophage ADAR1 microRNA122 BCL2A1 Apoptosis

Understanding energetic disorder in electron-deficient-core-based non-fullerene solar cells

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Science China Chemistry 2020年第8期63卷 1159-1168页

作者： Jun Yuan chujun Zhang Honggang Chen Can Zhu Sin Hang Cheung Beibei Qiu Fangfang Cai Qingya Wei Wei Liu Hang yin Rui Zhang Jidong Zhang Ye Liu Huotian Zhang Weifang Liu Hongjian Peng Junliang Yang Lei Meng Feng Gao Shukong So Yongfang Li yingping Zou College of Chemistry and Chemical Engineering Central South UniversityChangsha 410083China Department of Physics and Institute of Advanced Materials Hong Kong Baptist UniversityHong KongChina Beijing National Laboratory for Molecular Sciences Institute of ChemistryChinese Academy of SciencesBeijing 100190China Department of Physics Chemistry and Biology(IFM)Linkoping UniversityLinkdping 58183Sweden State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China Hunan Key Laboratory for Super-microstructure and Ultrafast Process School of Physics and ElectronicChangsha 410083China

Recent advances in material design for organic solar cells(OSCs)are primarily focused on developing near-infrared nonfullerene acceptors,typically A-DA′D-A type acceptors(where A abbreviates an electron-withdrawing moiety and D,an electron-donor moiety),to achieve high external quantum efficiency while maintaining low voltage ***,the charge transport is still constrained by unfavorable molecular conformations,resulting in high energetic disorder and limiting the device ***,a facile design strategy is reported by introducing the"wing"(alkyl chains)at the terminal of the DA′D central core of the A-DA′D-A type acceptor to achieve a favorable and ordered molecular orientation and therefore facilitate charge carrier *** from the reduced disorder,the electron mobilities could be significantly enhanced for the"wing"-containing *** carefully changing the length of alkyl chains,the mobility of acceptor has been tuned to match with that of donor,leading to a minimized charge imbalance factor and a high fill factor(FF).We further provide useful design strategies for highly efficient OSCs with high FF.

关键词： non-fullerene organic solar cells electron-deficient-core energetic disorder molecular design strategy

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黄登水电站工程金属结构设计与布置

水力发电 2019年第6期45卷 96-99页

作者：尹显清贾海波王处军中国电建集团昆明勘测设计研究院有限公司

对黄登水电站泄水建筑物、引水建筑物、尾水建筑物和导流建筑物4个系统的金属结构设备的设计、布置及操作条件进行了详细介绍,并简述了闸门和启闭机设备的操作运行。目前电站所有机组均已发电,金属结构设备均已投入运行,运行状况良好。

关键词：金属结构设计与布置操作运行黄登水电站

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JVM 11中的G1 GC关键参数分析

数字通信世界 2024年第6期 103-105页

作者：丛储俊殷军普上海威士顿信息技术股份有限公司上海200052

Java是目前大数据组件的主要开发语言,JVM 11是目前成熟的大数据平台所支持的最新的LTS(Long Term Support)版本,G1 GC(Garbage-First Collector)是JVM 11的缺省GC方式,所以掌握JVM 11中的G1 GC的关键参数对于Java应用特别是长期运行的... 详细信息

Java是目前大数据组件的主要开发语言,JVM 11是目前成熟的大数据平台所支持的最新的LTS(Long Term Support)版本,G1 GC(Garbage-First Collector)是JVM 11的缺省GC方式,所以掌握JVM 11中的G1 GC的关键参数对于Java应用特别是长期运行的服务端应用有很重要的意义。该文对G1 GC的关键概念进行了介绍,分析了关键参数的的含义,给出了适用于Apache H Base的G1 GC参数参考。

关键词： JVM GC G1 GC Apache H Base

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基于大数据分析的校园热点区域探测学生环境行为的研究

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电子技术（上海） 2021年第5期50卷 186-188页

作者：李楚君殷颖迪张丽钟康杰西安欧亚学院陕西710065

分析表明,随着计算机和定位技术的快速发展,大数据的分析和量化成为研究热点。学生定位和行为数据能反映出学生行为规律和特征,对校园环境规划设计具有重要意义。以2019年全年西安欧亚学院学生WiFi定位数据为基础,阐述将校园划分为10×1... 详细信息

分析表明,随着计算机和定位技术的快速发展,大数据的分析和量化成为研究热点。学生定位和行为数据能反映出学生行为规律和特征,对校园环境规划设计具有重要意义。以2019年全年西安欧亚学院学生WiFi定位数据为基础,阐述将校园划分为10×10的网格,采用K-Mediods算法聚类得到热点数据集,并将其转换为热力图,对照校园地图提取出学生聚集热点区域。在此基础上,对校园公共空间的聚集密度及学生环境行为进行分类,对比分析热点区域数据和行为数据间的关联度,归纳校园环境中公共行为的内在成因,为环境规划提供了基于行为数据的科学预测及评估。

关键词：大数据信息分析校园热点区域 WiFi 定位数据环境行为

对新型冠状病毒肺炎疫情防控形势下大型方舱医院急救培训与救治体系建设的思考与探讨

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医学争鸣 2022年第S1期13卷 56-59页

作者：吴林赵鹏王倩梅段楚君尹文赵威上海国家会展中心方舱医院三分院四分队上海201702 空军军医大学西京医院急诊科陕西西安710032

自2020年1月武汉市抗击新型冠状病毒肺炎疫情以来,我国创新性地建设了作为大型集中医学隔离观察场所的方舱医院,被多次应用于大型或特大型城市疫情暴发后批量轻症患者和无症状感染者的收容,有效地杜绝了病毒在社区内传播。本文基于2022... 详细信息

自2020年1月武汉市抗击新型冠状病毒肺炎疫情以来,我国创新性地建设了作为大型集中医学隔离观察场所的方舱医院,被多次应用于大型或特大型城市疫情暴发后批量轻症患者和无症状感染者的收容,有效地杜绝了病毒在社区内传播。本文基于2022年4月至5月在上海国家会展中心方舱医院工作中的经验思考对方舱医院急救培训与救治体系的建设加以探讨。

关键词：新型冠状病毒肺炎大型方舱医院急救培训与救治体系

西安户外运动人群夏季生理参数及热舒适的关联性研究

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制冷与空调（四川） 2022年第2期36卷 317-323页

作者：罗薇殷颖迪井文强李楚君张锦李婷潘家辉西安欧亚学院人居环境学院西安710065

不同人群对热条件的偏好可能会有所不同,这取决于本地的气候特点。当人群从一个气候区迁移到另一个气候区时,因迁移形成的气候地域变化被作为影响人体生理参数和热舒适的重要因素。通过招募大一学生(n=61)于2021年5月16日至5月28日在西... 详细信息

不同人群对热条件的偏好可能会有所不同,这取决于本地的气候特点。当人群从一个气候区迁移到另一个气候区时,因迁移形成的气候地域变化被作为影响人体生理参数和热舒适的重要因素。通过招募大一学生(n=61)于2021年5月16日至5月28日在西安校园里进行户外运动。研究期间对热舒适和心率、氧饱和度等生理参数进行了调查。结果表明,非本地人的心率高于本地人,但本地人的血氧饱和度高于非本地人。本地人与非本地人在热舒适和热感觉方面存在明显差异,非本地人和本地人相比对环境的忍受力更低,在夏季更加不耐热。对于了解已适应人群(本地人)和未适应人群(非本地人)的生理参数和热舒适都是必要的。尤其是未来在运动状态中解决热不适,预防更严重的热相关疾病提供参考。

关键词：户外运动热舒适生理参数生理等效温度