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Powell dynamic identification of displacement parameters of indeterminate thin-walled curve box based on FCSE theory

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Acta Mechanica Sinica 2011年第3期27卷 452-460页

作者： Jian Zhang chu-wei zhou Jia-Shou Zhuo College of Aerospace Engineering Nanjing University of Aeronautics and Astronautics 210016 Nanjing China College of Mechanics and Material Hohai University 210098 Nanjing China

The FCSE controlling equation of pinned thinwalled curve box was derived and the indeterminate problem of continuous thin-walled curve box with diaphragm was solved based on flexibility theory. With Bayesian statistical theory,dynamic Bayesian error function of displacement parameters of indeterminate curve box was founded. The corresponding formulas of dynamic Bayesian expectation and variance were deduced. Combined with one-dimensional Fibonacci automatic search scheme of optimal step size,the Powell optimization theory was utilized to research the stochastic identification of displacement parameters of indeterminate thin-walled curve box. Then the identification steps were presented in detail and the corresponding calculation procedure was compiled. Through some classic examples,it is obtained that stochastic performances of systematic parameters and systematic responses are simultaneously deliberated in dynamic Bayesian error function. The one-dimensional optimization problem of the optimal step size is solved by adopting Fibonacci search method. And the Powell identification of displacement parameters of indeterminate thin-walled curve box has satisfied numerical stability and convergence,which demonstrates that the presented method and the compiled procedure are correct and *** parameters鈥？iterative processes,the Powell theory is irrelevant with the calculation of finite curve strip element（FCSE） partial differentiation,which proves high computation effciency of the studied method.

关键词： Powell theory - Indeterminate curve box . Displacement parameters - Fibonacci search method.Flexibility theory

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基于Jeeves模式搜索理论地基参数的更新Bayes探测法（英文）

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2018年第9期19卷 691-703页

作者： Jian ZHANG Chao JIA chu-wei zhou Department of Mechanics and Structural Engineering Nanjing University of Aeronautics and Astronautics School of Civil Engineering Shandong University

目的:通过Jeeves模式搜索理论建立弹性地基参数的更新Bayes探测分析模型,以及获得地基参数的寻优搜索结果。创新点:1.根据Bayes统计理论,推导更新Bayes误差函数。2.结合最优步长的抛物线插值理论,推求地基参数的Jeeves模式搜索寻优方法... 详细信息

目的:通过Jeeves模式搜索理论建立弹性地基参数的更新Bayes探测分析模型,以及获得地基参数的寻优搜索结果。创新点:1.根据Bayes统计理论,推导更新Bayes误差函数。2.结合最优步长的抛物线插值理论,推求地基参数的Jeeves模式搜索寻优方法,建立地基参数的探测分析模型。方法:1.根据Bayes统计理论,推导更新Bayes误差函数(公式(4))及误差函数对地基参数的梯度表达式(公式(5))。2.根据中厚度弹性地基板理论,推求Winkler地基上板的控制微分方程(公式(19))和Fourier闭式解(公式(20))。3.提出最优步长的抛物线插值寻优方案,并结合Jeeves模式搜索理论建立弹性地基参数的更新Bayes探测分析模型。结论:1.基于更新Bayes理论,可研究地基参数的Jeeves模式搜索分析模型,且地基参数的探测迭代过程具有良好的稳定性与收敛性。2.更新Bayes误差函数能同时考虑不同量测次数和不同测点的位移实测信息,计算效率较高。3.与共轭梯度法和Kalman滤波方法不同的是,Jeeves模式搜索理论的迭代过程不涉及误差函数偏导数计算,避免了迭代过程的误差累积。

关键词： Jeeves模式搜索理论更新Bayes误差函数探测地基参数 Fourier闭式解

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基于广义Bayes理论地基参数的Powell反演力学模型（英文）

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2017年第7期18卷 567-578页

作者： Jian ZHANG chu-wei zhou Chao JIA Jing LIN Department of Mechanics and Structural Engineering Nanjing University of Aeronautics and Astronautics School of Civil Engineering Shandong University Institute of Structural Engineering Tongji University

目的:通过Powell优化反演方法建立Winkler地基参数的反演力学模型,获得地基参数的稳定数值解。创新点:根据Bayes理论,推导广义Bayes目标函数;利用Fourier变换,推求Winkler地基上简支板的Fourier闭式解,建立地基参数的反演力学模型。方法... 详细信息

目的:通过Powell优化反演方法建立Winkler地基参数的反演力学模型,获得地基参数的稳定数值解。创新点:根据Bayes理论,推导广义Bayes目标函数;利用Fourier变换,推求Winkler地基上简支板的Fourier闭式解,建立地基参数的反演力学模型。方法:1.根据Bayes理论,推导广义Bayes目标函数(公式(4))及地基参数的广义Bayes均值和方差表达式(公式(9)和(11));2.引入Mindlin理论,推导Winkler地基上板的控制微分方程,推求Winkler地基上简支板的Fourier闭式解;3.提出步长的一维自动寻优方案,结合Powell优化方法建立Winkler地基参数的广义Bayes反演力学模型。结论:1.地基参数的反演迭代过程稳定收敛于参数真值;2.与Kalman滤波方法和共轭梯度法不同,Powell优化方法的迭代过程不涉及目标函数的偏导数计算;3.广义Bayes目标函数能同时考虑不同测量点和不同测量次数的位移实测资料,计算效率更高。

关键词： Powell反演力学模型地基参数 Bayes目标函数随机性

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Effect of Grinding Techniques on Absorbing Characteristics of Short Iron Fibers

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Journal of Wuhan University of Technology(Materials Science) 2007年第3期22卷 400-403页

作者：程海峰 Key Lab of Advancd Ceramic Fibers & Composites National University of Defense Technology

Microwave-absorbing properties of iron fibers can be adjusted by their aspect ratio. This paper presents several modification techniques for grinding long iron fibers to a suitable aspect ratio. The grinding instruments include pulsator, jet mill and muller. The aspect ratio distribution, microstructure, electromagnetic parameter and reflectivity of the samples were analyzed and discussed in detail. The results show that the fractions of 5〈aspect ratio〈40 for the three methods are 69.03%, 81.11% and 80.2% , respectively, that is, suitable short iron fibers can be obtained by the jet mill and muller. Furthermore, the short iron fibers milled by jet mill and muller have better absorbing propterties than those obtained by the pulsator under the same condition. Therefore, their microwave absorption properties can be improved by regulating the electromagnetic parameters with grinding.

关键词： short iron fiber electromagnetic parameter microwave-absorbing property

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Treadmill exercise in combination with acousto-optic and olfactory stimulation improves cognitive function in APP/PS1 mice through the brain-derived neurotrophic factor-and Cygb-associated signaling pathways

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Neural Regeneration Research 2025年第9期20卷 2706-2726页

作者： Biao Xiao Chaoyang chu Zhicheng Lin Tianyuan Fang Yuyu zhou chuxia Zhang Jianghui Shan Shiyu Chen Liping Li Department of Physiology and Pharmacology Health Science CenterNingbo UniversityNingboZhejiang ProvinceChina Ningbo Key Laboratory of Behavioral Neuroscience Health Science CenterNingbo UniversityNingboZhejiang ProvinceChina Key Laboratory of Addiction Research of Zhejiang Province NingboZhejiang ProvinceChina

A reduction in adult neurogenesis is associated with behavioral abnormalities in patients with Alzheimer's ***,enhancing adult neurogenesis represents a promising therapeutic approach for mitigating disease symptoms and ***,nonpharmacological interventions aimed at inducing adult neurogenesis are currently *** individual non-pharmacological interventions,such as aerobic exercise,acousto-optic stimulation,and olfactory stimulation,have shown limited capacity to improve neurogenesis and cognitive function in patients with Alzheimer's disease,the therapeutic effect of a strategy that combines these interventions has not been fully *** this study,we observed an age-dependent decrease in adult neurogenesis and a concurrent increase in amyloid-beta accumulation in the hippocampus of amyloid precursor protein/presenilin 1 mice aged 2-8 *** deposition became evident at 4 months,while neurogenesis declined by 6 months,further deteriorating as the disease ***,following a 4-week multifactor stimulation protocol,which encompassed treadmill running(46 min/d,10 m/min,6 days per week),40 Hz acousto-optic stimulation(1 hour/day,6 days/week),and olfactory stimulation(1 hour/day,6 days/week),we found a significant increase in the number of newborn cells(5'-bromo-2'-deoxyuridine-positive cells),immature neurons(doublecortin-positive cells),newborn immature neurons(5'-bromo-2'-deoxyuridine-positive/doublecortin-positive cells),and newborn astrocytes(5'-bromo-2'-deoxyuridine-positive/glial fibrillary acidic protein-positive cells).Additionally,the amyloid-beta load in the hippocampus *** findings suggest that multifactor stimulation can enhance adult hippocampal neurogenesis and mitigate amyloid-beta neuropathology in amyloid precursor protein/presenilin 1 ***,cognitive abilities were improved,and depressive symptoms were alleviated in amyloid precursor protein/presenilin 1 mice

关键词： acousto-optic stimulation adult neurogenesis Alzheimer's disease amyloid precursor protein/presenilin 1 mice amyloid-beta deposition brain cell apoptosis cognitive impairment depression-like behavior involuntary treadmill exercise olfactory stimulation serum metabolites

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A low redox potential and long life organic anode material for sodium-ion batteries

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Journal of Energy Chemistry 2025年第1期100卷 557-564页

作者： Zhi Li Yang wei Kang zhou Xin Huang Xing zhou Jie Xu Taoyi Kong Junwei Lucas Bao Xiaoli Dong Yonggang Wang Department of Chemistry and Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials Institute of New Energy Collaborative Innovation Center of Chemistry for Energy Materials (iChEM) Fudan University Department of Chemistry Boston College School of Materials Science and Engineering Anhui University of Technology

Sodium-ion batteries （SIBs） with organic electrodes are an emerging research direction due to the sustainability of organic materials based on elements like C,H,O,and sodium ***,organic electrode materials for SIBs are mainly used as cathodes because of their relatively high redox potentials（>1 V）.Organic electrodes with low redox potential that can be used as anode are ***,a novel organic anode material （tetrasodium 1,4,5,8-naphthalenetetracarboxylate,Na4TDC） has been developed with low redox potential （<0.7 V） and excellent cyclic *** three-sodium storage mechanism was demonstrated with various in-situ/ex-situ spectroscopy and theoretical calculations,showing a high capacity of 208 mAh/g and an average decay rate of merely 0.022%per ***,the Na4TDC-hard carbon composite can further acquire improved capacity and cycling stability for 1200 cycles even with a high mass loading of up to 20 mg *** pairing with a thick Na3V2（PO4）3cathode (20.6 mg cm-2),the as-fabricated full cell exhibited high operating voltage （2.8 V）,excellent rate performance and cycling stability with a high capacity retention of 88.7% after 200 cycles,well highlighting the Na4TDC anode material for SIBs.

关键词： Organic anode material Low redox potential Composite anode Sodium-ion batteries

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PI3K/AKT signaling and neuroprotection in ischemic stroke:molecular mechanisms and therapeutic perspectives

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Neural Regeneration Research 2025年第10期20卷 2758-2775页

作者： Tianlong Liu Xiaolin Li Xiaowei zhou wei Chen Aidong Wen Minna Liu Yi Ding Department of Pharmacy Xijing HospitalFourth Military Medical UniversityXi’anShaanxi ProvinceChina Department of Pharmacy The 940 Hospital of Joint Logistics Support Forces of Chinese PLALanzhouGansu ProvinceChina Department of Pharmacy The 944 Hospital of Joint Logistics Support Forces of Chinese PLAJiuquanGansu ProvinceChina Department of Nephrology The 940 Hospital of Joint Logistics Support Forces of Chinese PLALanzhouGansu ProvinceChina

It has been reported that the PI3K/AKT signaling pathway plays a key role in the pathogenesis of ischemic *** a result,the development of drugs targeting the PI3K/AKT signaling pathway has attracted increasing attention from *** article reviews the pathological mechanisms and advancements in research related to the signaling pathways in ischemic stroke,with a focus on the PI3K/AKT signaling *** key findings include the following:(1)The complex pathological mechanisms of ischemic stroke can be categorized into five major types:excitatory amino acid toxicity,Ca^(2+)overload,inflammatory response,oxidative stress,and apoptosis.(2)The PI3K/AKT-mediated signaling pathway is closely associated with the occurrence and progression of ischemic stroke,which primarily involves the NF-κB,NRF2,BCL-2,mTOR,and endothelial NOS signaling pathways.(3)Natural products,including flavonoids,quinones,alkaloids,phenylpropanoids,phenols,terpenoids,and iridoids,show great potential as candidate substances for the development of innovative anti-stroke medications.(4)Recently,novel therapeutic techniques,such as electroacupuncture and mesenchymal stem cell therapy,have demonstrated the potential to improve stroke outcomes by activating the PI3K/AKT signaling pathway,providing new possibilities for the treatment and rehabilitation of patients with ischemic *** investigations should focus on the direct regulatory mechanisms of drugs targeting the PI3K/AKT signaling pathway and their clinical translation to develop innovative treatment strategies for ischemic stroke.

关键词： apoptosis autophagy inflammation ischemic stroke neuroprotection oxidative stress pathogenesis phosphatidylinositol 3-kinase protein kinase B therapeutics

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Defects‑Rich Heterostructures Trigger Strong Polarization Coupling in Sulfides/Carbon Composites with Robust Electromagnetic Wave Absorption

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Nano-Micro Letters 2025年第1期17卷 528-547页

作者： Jiaolong Liu Siyu Zhang Dan Qu Xuejiao zhou Moxuan Yin Chenxuan Wang Xuelin Zhang Sichen Li Peijun Zhang Yuqi zhou Kai Tao Mengyang Li Bing wei Hongjing Wu Mengyang Li Bing wei Hongjing Wu School of Physics Xidian UniversityXi’an 710071People’s Republic of China School of Advanced Materials and Nanotechnology State Key Discipline Laboratory of Wide Band Gap Semiconductor TechnologyXidian UniversityXi’an 710071People’s Republic of China School of Microelectronics Xidian UniversityXi’an 710071People’s Republic of China School of Telecommunication Engineering Xidian UniversityXi’an 710071People’s Republic of China MOE Key Laboratory of Material Physics and Chemistry Under Extraordinary School of Physical Science and TechnologyNorthwestern Polytechnical UniversityXi’an 710072People’s Republic of China The Ministry of Education Key Laboratory of Micro and Nano Systems forAerospace School of Mechanical EngineeringNorthwestern PolytechnicalUniversityXi’an 710072People’s Republic of China

Defects-rich heterointerfaces integrated with adjustable crystalline phases and atom vacancies,as well as veiled dielectric-responsive character,are instrumental in electromagnetic *** methods,however,constrain their delicate ***,an innovative alternative is proposed:carrageenan-assistant cations-regulated(CACR)strategy,which induces a series of sulfides nanoparticles rooted in situ on the surface of carbon *** unique configuration originates from strategic vacancy formation energy of sulfides and strong sulfides-carbon support interaction,benefiting the delicate construction of defects-rich heterostructures in M_(x)S_(y)/carbon composites(M-CAs).Impressively,these generated sulfur vacancies are firstly found to strengthen electron accumulation/consumption ability at heterointerfaces and,simultaneously,induct local asymmetry of electronic structure to evoke large dipole moment,ultimately leading to polarization coupling,i.e.,defect-type interfacial ***“Janus effect”(Janus effect means versatility,as in the Greek two-headed Janus)of interfacial sulfur vacancies is intuitively confirmed by both theoretical and experimental investigations for the first ***,the sulfur vacancies-rich heterostructured Co/Ni-CAs displays broad absorption bandwidth of 6.76 GHz at only 1.8 mm,compared to sulfur vacancies-free CAs without any dielectric *** defects-rich heterostructures,this one-pot CACR strategy may steer the design and development of advanced nanomaterials,boosting functionality across diverse application domains beyond electromagnetic response.

关键词： Defects-rich heterointerfaces Sulfides Polarization coupling Electromagnetic wave absorption

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The cGAS-STING-interferon regulatory factor 7 pathway regulates neuroinflammation in Parkinson's disease

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Neural Regeneration Research 2025年第8期20卷 2361-2372页

作者： Shengyang zhou Ting Li wei Zhang Jian Wu Hui Hong wei Quan Xinyu Qiao chun Cui Chenmeng Qiao weijiang Zhao Yanqin Shen Laboratory of Neurodegenerative and Neuroinjury Diseases Wuxi Medicine SchoolJiangnan UniversityWuxiJiangsu ProvinceChina

Interferon regulatory factor 7 plays a crucial role in the innate immune ***,whether interferon regulatory factor 7-mediated signaling contributes to Parkinson's disease remains *** we report that interferon regulatory factor 7 is markedly up-regulated in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease and co-localizes with microglial *** the selective cyclic guanosine monophosphate adenosine monophosphate synthase inhibitor RU.521 and the stimulator of interferon genes inhibitor H151 effectively suppressed interferon regulatory factor 7 activation in BV2 microglia exposed to 1-methyl-4-phenylpyridinium and inhibited transformation of mouse BV2 microglia into the neurotoxic M1 *** addition,si RNA-mediated knockdown of interferon regulatory factor 7 expression in BV2 microglia reduced the expression of inducible nitric oxide synthase,tumor necrosis factorα,CD16,CD32,and CD86 and increased the expression of the anti-inflammatory markers ARG1 and *** together,our findings indicate that the cyclic guanosine monophosphate adenosine monophosphate synthase-stimulator of interferon genes-interferon regulatory factor 7 pathway plays a crucial role in the pathogenesis of Parkinson's disease.

关键词： cyclic guanosine monophosphate adenosine monophosphate synthase H151 interferon regulatory factor 7 M1 phenotype neurodegenerative disease neuroinflammation Parkinson’s disease RU521 STING type I interferon

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High-dimensional large-scale mixed-type data imputation under missing at random

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Science China Mathematics 2025年

作者： wei Liu Guizhen Li Ling zhou Lan Luo School of Mathematics Sichuan University Center of Statistical Research and School of Statistics Southwestern University of Finance and Economics Department of Statistics and Actuarial Science University of Iowa

Missingness in mixed-type variables is commonly encountered in a variety of areas. The requirement of complete observations necessities data imputation when a moderate or large proportion of data is ***, inappropriate imputation would downgrade the performance of machine learning algorithms, leading to bad predictions and unreliable statistical inference. For high-dimensional large-scale mixed-type missing data, we develop a computationally efficient imputation method, missing value imputation via generalized factor models（MIG）, under missing at random. The proposed MIG method allows missing variables to be of different types,including continuous, binary, and count variables, and are scalable to both data size n and variable dimension p while existing imputation methods rely on restrictive assumptions such as the same type of missing variables,the low dimensionality of variables, and a limited sample size. We explicitly show that the imputation error of the proposed MIG method diminishes to zero with the rate Op(max{n-1/2, p-1/2}) as both n and p tend to infinity. Five real datasets demonstrate the superior empirical performance of the proposed MIG method over existing methods that the average normalized absolute imputation error is reduced by 5.3%–34.1%.

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