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Clinical efficacy of modified Kamikawa anastomosis in patients with laparoscopic proximal gastrectomy

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World Journal of Gastrointestinal Surgery 2024年第1期16卷 113-123页

作者： chu-Ying wu Jian-An Lin Kai Ye Department of Gastrointestinal Surgery The Second Affiliated Hospital of Fujian Medical UniversityQuanzhou 362000Fujian ProvinceChina

BACKGROUND With the increasing incidence of proximal gastric cancer,laparoscopic proximal gastrectomy has been ***,reflux esophagitis often occurs after traditional esophagogastric *** order to solve this problem,several methods of digestive tract reconstruction have emerged,but the most satisfying method remains to be ***,we modified traditional Kamikawa anastomosis to investigate the appropriate digestive tract reconstruction in laparo-scopic proximal *** the patients were successfully operated on without conversion to *** duration of operation and digestive tract reconstruction were 203.500(150-224)min and 87.500(73-111)min,*** intraoperative amount of bleeding was 20.500 mL±0.696 *** time of postoperative first flatus,the first postoperative fluid intake,and the postoperative length of stay were 2(1-3)d,4(3-5)d,and 9(8-10)d,*** the patients were followed up for 12-23 *** body mass index at 6 and 12 months after surgery were 22.577 kg/m2±3.098 kg/m2 and 22.594 kg/m2±3.207 kg/m2,*** nutrition risk screening 2002 score,the patient-generated subjective global assessment score,and the gastroesophageal reflux disease scale score were good at 6 and 12 months after *** esophagitis and anastomotic stenosis were not observed in any of the patients during their 12-month postoperative gastroscopy or upper gastrointestinal tract *** the patients exhibited no tumor recurrence or *** The modified Kamikawa anastomosis is safe and feasible for laparoscopic proximal gastrectomy and has good antireflux effects and nutritional status.

关键词： Modified Kamikawa anastomosis Laparoscopy Proximal gastrectomy Antireflux

A data-driven approach to RUL prediction of tools

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Advances in Manufacturing 2024年第1期12卷 6-18页

作者： Wei Li Liang-Chi Zhang chu-Han wu Yan Wang Zhen-Xiang Cui Chao Niu Department of Mechanical Engineering University College LondonLondonWC1E 7JEUK Shenzhen Key Laboratory of Cross-Scale Manufacturing Mechanics Southern University of Science and TechnologyShenzhen518055GuangdongPeople’s Republic of China SUSTech Institute for Manufacturing Innovation Southern University of Science and TechnologyShenzhen518055GuangdongPeople’s Republic of China Department of Mechanics and Aerospace Engineering Southern University of Science and TechnologyShenzhen518055GuangdongPeople’s Republic of China School of Mechanical and Manufacturing Engineering The University of New South WalesKensingtonNSW2052Australia Baoshan Iron&Steel Co. Ltd.Shanghai200941People’s Republic of China

An effective and reliable prediction of the remaining useful life(RUL)of a tool is important to a metal forming process because it can significantly reduce unexpected maintenance,avoid machine shutdowns and increase system *** study proposes a new data-driven approach to the RUL prediction for metal forming processes under multiple contact sliding *** data-driven approach took advantage of bidirectional long short-term memory(BLSTM)and convolutional neural networks(CNN).A pre-trained lightweight CNN-based network,WearNet,was re-trained to classify the wear states of workpiece surfaces with a high accuracy,then the classification results were passed into a BLSTM-based regression model as inputs for RUL *** experimental results demonstrated that this approach was able to predict the RUL values with a small error(below 5%)and a low root mean square error(RMSE)(around 1.5),which was more superior and robust than the other state-of-the-art methods.

关键词： Remaining useful life(RUL) Bidirectional long short-term memory(BLSTM) Data-driven approach Metal forming

Risk factors for the prognosis of colon cancer

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World Journal of Gastrointestinal Oncology 2024年第8期16卷 3738-3740页

作者： chu-Ying wu Kai Ye Department of Gastrointestinal Surgery The Second Affiliated Hospital of Fujian Medical UniversityQuanzhou 362000Fujian ProvinceChina

A study on clinical outcomes and prognostic factors in T4N0M0 colon cancer patients after R0 resection revealed that ileostomy,T stage,right hemicolectomy,irregular follow-up,and CA199 level were independent risk factors affecting overall survival.T4-stage cancer invades the entire thickness of the intestinal tract,increasing the difficulty of treatment and the risk of recurrence,and requires a combination of chemotherapy,immunotherapy,and targeted therapy to control the spread of cancer *** prognosis of right hemicolectomy is significantly worse than that of left hemicolectomy,and right hemicolectomy is an independent risk factor for a poor *** age,histopathological type,and lymph node metastasis are also risk factors for colon cancer.

关键词： Risk factor Prognosis Colon cancer Tumour stage Right hemicolectomy

Petrogenesis and Tectonic Implications of the Early Triassic Nianzi Adakitic Granite Unit in the Yanshan Fold and Thrust Belt:New Constraints from U-Pb Geochronology and Sr-Nd-Hf Isotopes

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Acta Geologica Sinica(English Edition) 2024年第1期98卷 50-66页

作者： ZHANG Huijun wu chu HE Fubing WANG Biren CUI Yubin LIU Zhenghua YOU Shina DONG Jing Development and Research Center of the China Geological Survey Beijing 100037China Beijing Institute of the Geological Survey Beijing 100095China Institute of Disaster Prevention LangfangHebei 065201China

The Nianzi granite unit,which includes the Nianzi,Xiaolianghou and Xiawopu granitic intrusions,is a significant component of the northern part of the North China Craton(NCC)and is situated in the Yanshan fold and thrust belt(YFTB).However,there is still debate regarding the tectonic evolutionary history of the YFTB during the late Permian to Triassic period,specifically regarding the timing of subduction and collision between the NCC and the Paleo-Asian *** Nianzi granite unit exhibits unique petrological,geochronological and geochemical signatures that shed light on the tectonic evolutionary history of the *** study presents detailed petrology,whole-rock geochemistry,together with Sr-Nd isotopic,zircon U-Pb dating and Lu-Hf isotopic data of the granites within the Nianzi granite *** findings demonstrate that the granites primarily consist of subhedral K-feldspar,plagioclase,quartz,minor biotite and hornblende,with accessory titanite,apatite,magnetite and *** U-Pb dating indicates that the Xiaolianghou granite was emplaced at 247.5±0.62 ***,the adakitic characteristics of the Nianzi,Xiawopu and Xiaolianghou granitic intrusions,such as high Sr and Ba contents and high ratios of Sr/Y and(La/Yb)N,combined with negative Sr-Nd and Lu-Hf isotopes(87Sr/86Sr)i=0.705681–0.7057433,εNd(t)=−21.98 to−20.97,zirconεHf(t)=−20.26 to−9.92,as well as the I-type granite features of high SiO_(2),Na_(2)O and K_(2)O/Na_(2)O ratios,enriched Rb,K,Sr and Ba,along with depleted Th,U,Nb,Ta,P and Ti,suggest that the Nianzi granitic unit was mainly derived from the partial melting of a thickened lower crust containing hydrous,calc-alkaline to high-K calc-alkaline,mafic to intermediate metamorphic *** light of these parameters,we further integrate our data with previous studies and conclude that the Nianzi granitic unit was generated in a post-collisional extensional environment during the Early Triassic.

关键词： tectonic evolution zircon geochronology Sr-Nd-Hf isotopes Nianzi granite unit Yanshan fold and thrust belt

Hepatocyte growth factor enhances the ability of dental pulp stem cells to ameliorate atherosclerosis in apolipoprotein E-knockout mice

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World Journal of Stem Cells 2024年第5期16卷 575-590页

作者： Han Duan Ning Tao Lin Lv Kai-Xin Yan Yong-Gang You Zhuang Mao Chang-Yao Wang Xue Li Jia-Yan Jin chu-Tse wu Hua Wang School of Life Sciences Hebei UniversityBaoding 071002Hebei ProvinceChina Beijing Institute of Radiation Medicine Beijing 100850China Department of Cardiology The Sixth Medical CentreChinese People’s Liberation Army General HospitalBeijing 100037China Department of Orthopaedics The Fourth Medical CentreChinese People’s Liberation Army General HospitalBeijing 100853China Third Cadet Regiment School of Basic Medical ScienceAir Force Medical UniversityXi’an 710032Shaanxi ProvinceChina

BACKGROUND Atherosclerosis(AS),a chronic inflammatory disease of blood vessels,is a major contributor to cardiovascular *** pulp stem cells(DPSCs)are capable of exerting immunomodulatory and anti-inflammatory effects by secreting cytokines and exosomes and are widely used to treat autoimmune and inflam-mation-related *** growth factor(HGF)is a pleiotropic cytokine that plays a key role in many inflammatory and autoimmune *** To modify DPSCs with HGF(DPSC-HGF)and evaluate the therapeutic effect of DPSC-HGF on AS using an apolipoprotein E-knockout(ApoE-/-)mouse model and an in vitro cellular *** ApoE-/-mice were fed with a high-fat diet(HFD)for 12 wk and injected with DPSC-HGF or Ad-Null modified DPSCs(DPSC-Null)through tail vein at weeks 4,7,and 11,respectively,and the therapeutic efficacy and mechanisms were analyzed by histopathology,flow cytometry,lipid and glucose measurements,real-time reverse transcription polymerase chain reaction(RT-PCR),and enzyme-linked immunosorbent assay at the different time points of the *** in vitro inflammatory cell model was established by using RAW264.7 cells and human aortic endothelial cells(HAOECs),and indirect co-cultured with supernatant of DPSC-Null(DPSC-Null-CM)or DPSC-HGF-CM,and the effect and mechanisms were analyzed by flow cytometry,RT-PCR and western *** factor-κB(NF-κB)activators and inhibitors were also used to validate the related signaling *** DPSC-Null and DPSC-HGF treatments decreased the area of atherosclerotic plaques and reduced the expression of inflammatory factors,and the percentage of macrophages in the aorta,and DPSC-HGF treatment had more pronounced *** treatment had no effect on serum lipoprotein *** FACS results showed that DPSCs treatment reduced the percentages of monocytes,neutrophils,and M1 macrophages in the peripheral blood and ***-Null-CM and DPSC-HGF-CM reduced adhesion molecule expression in tu

关键词： Atherosclerosis Apolipoprotein E-knockout mice Cell therapy Dental pulp stem cells Hepatocyte growth factor

当代陶瓷艺术的叙事策略与美学转向——以2023“瓷的旅程”双年展为视域

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中国陶瓷 2024年第8期60卷 112-119页

作者：吴楚黄勇景德镇陶瓷大学

新时期，中国艺术创作与处于转捩期的社会境况相吻合，作品文本、当代陶瓷艺术演变及由此产生的叙事和美学转向之间呈现独特的视觉面相。叙事策略上，兼顾宏大叙事、微观叙事和融合叙事的模式表达；美学探索上，由客观形式美向生活美学... 详细信息

新时期，中国艺术创作与处于转捩期的社会境况相吻合，作品文本、当代陶瓷艺术演变及由此产生的叙事和美学转向之间呈现独特的视觉面相。叙事策略上，兼顾宏大叙事、微观叙事和融合叙事的模式表达；美学探索上，由客观形式美向生活美学、审美主义、社会学转向，陶瓷艺术在“现代性”语境中逐渐形成其价值传递和美学表达的新的叙事理路。深入研究此课题，对现代转型之后理解中国陶瓷艺术的发展脉络和方向，推动中国陶瓷美学理论的发展具有重要的文化当代性意义。

关键词：陶瓷艺术双年展叙事美学现代性

钙调控马铃薯产量、品质和抗逆性的关键作用研究进展

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植物营养与肥料学报 2024年第6期30卷 1199-1210页

作者：吴楚红黄成东养分资源高效利用全国重点实验室/植物−土壤相互作用教育部重点实验室/中国农业大学资源与环境学院北京100193

马铃薯作为全球及我国第四大粮食作物,在保障粮食安全、改善营养健康等国家发展战略方面发挥着重要作用。马铃薯产量、品质与养分管理有着紧密联系,作为马铃薯的一种必需营养元素,钙在马铃薯生长发育过程中起着营养和信使的双重功能。... 详细信息

马铃薯作为全球及我国第四大粮食作物,在保障粮食安全、改善营养健康等国家发展战略方面发挥着重要作用。马铃薯产量、品质与养分管理有着紧密联系,作为马铃薯的一种必需营养元素,钙在马铃薯生长发育过程中起着营养和信使的双重功能。本文较为系统地总结了马铃薯地下部根茎结构特性与钙养分吸收、分布的关系,钙在提升马铃薯产量与品质,增强马铃薯抗逆性的关键作用,以期为匹配土壤−作物系统的马铃薯钙肥产品创制与田间钙养分实时智能精准高效管理提供科学依据,提升马铃薯产量与品质,助推马铃薯绿色生产与主粮化战略行动。

关键词：马铃薯钙养分管理产量与品质抗逆性

Correlation between Combined Urinary Metal Exposure and Grip Strength under Three Statistical Models:A Cross-sectional Study in Rural Guangxi

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Biomedical and Environmental Sciences 2024年第1期37卷 3-18页

作者： LIANG Yu Jian RONG Jia Hui WANG Xue Xiu CAI Jian Sheng QIN Li Dong LIU Qiu Mei TANG Xu MO Xiao Ting WEI Yan Fei LIN Yin Xia HUANG Shen Xiang LUO Ting Yu GOU Ruo Yu CAO Jie Jing HUANG chu wu LU Yu Fu QIN Jian ZHANG Zhi Yong Department of Environmental and Occupational Health School of Public HealthGuangxi Medical UniversityNanning 530021GuangxiChina Key Laboratory of Tumor Immunology and Microenvironmental Regulation Guilin Medical UniversityGuilin 541199GuangxiChina Department of Environmental Health and Occupational Medicine School of Public HealthGuilin Medical UniversityGuilin 541199GuangxiChina Guangxi Colleges and Universities Key Laboratory of Prevention and Control of Highly Prevalent Diseases Guangxi Medical UniversityNanning 530021GuangxiChina Guangxi Key Laboratory of Environment and Health Research Guangxi Medical UniversityNanning 530021GuangxiChina Key Laboratory of Longevity and Aging-related Diseases of Chinese Ministry of Education Guangxi Medical UniversityNanning 530021GuangxiChina Guangxi Health Commission Key Laboratory of Entire Lifecycle Health and Care Guilin Medical UniversityGuilin 541199GuangxiChina

Objective This study aimed to investigate the potential relationship between urinary metals copper(Cu),arsenic(As),strontium(Sr),barium(Ba),iron(Fe),lead(Pb)and manganese(Mn)and grip *** We used linear regression models,quantile g-computation and Bayesian kernel machine regression(BKMR)to assess the relationship between metals and grip *** In the multimetal linear regression,Cu(β=−2.119),As(β=−1.318),Sr(β=−2.480),Ba(β=0.781),Fe(β=1.130)and Mn(β=−0.404)were significantly correlated with grip strength(P<0.05).The results of the quantile g-computation showed that the risk of occurrence of grip strength reduction was−1.007(95%confidence interval:−1.362,−0.652;P<0.001)when each quartile of the mixture of the seven metals was *** kernel function regression model analysis showed that mixtures of the seven metals had a negative overall effect on grip strength,with Cu,As and Sr being negatively associated with grip strength *** the total population,potential interactions were observed between As and Mn and between Cu and Mn(P_(interactions) of 0.003 and 0.018,respectively).Conclusion In summary,this study suggests that combined exposure to metal mixtures is negatively associated with grip ***,Sr and As were negatively correlated with grip strength levels,and there were potential interactions between As and Mn and between Cu and Mn.

关键词： Urinary metals Handgrip strength Quantile g-computation Bayesian kernel machine regression

花岗质岩浆‒热液过渡阶段成矿响应及其岩石学记录

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大地构造与成矿学 2024年第3期48卷 460-477页

作者：洪涛翟明国高俊徐兴旺吴楚中山大学地球科学与工程学院广东省地球动力作用与地质灾害重点实验室广东珠海519082 南方海洋科学与工程广东省实验室(珠海) 广东珠海519082 中国科学院地质与地球物理研究所矿产资源研究重点实验室北京100029 中国科学院大学北京100049 中国科学院地球科学研究院北京100029 中国地质调查局发展研究中心北京100037

开展铜、锂和铍等关键金属的迁移富集机制与规律研究对于理解斑岩型和伟晶岩型矿床的成因具有重要意义。目前,大多数研究集中在岩浆形成到热液析出的“两端”演化过程,而岩石的后期热液蚀变是流体活动最活跃的时期,会强烈改造前期的成... 详细信息

开展铜、锂和铍等关键金属的迁移富集机制与规律研究对于理解斑岩型和伟晶岩型矿床的成因具有重要意义。目前,大多数研究集中在岩浆形成到热液析出的“两端”演化过程,而岩石的后期热液蚀变是流体活动最活跃的时期,会强烈改造前期的成矿过程,导致难以识别岩浆向热液转换阶段的成矿流体演化特征。近来,研究发现花岗质岩浆在岩浆‒热液过渡阶段存在熔体与热液流体共生的岩石学记录:斑岩型矿床成矿体系中保存的含矿岩墙/脉、富铜钼的“岩浆‒流体”囊状体、“羽丝状”含矿细晶岩脉群、蠕虫状石英斑晶中保留的熔体‒流体包裹体;伟晶岩型矿床成矿体系中保存的单向固结的石英脉和细晶岩、晶洞构造和文象结构等。这些岩石学证据有效记录了成矿流体从岩浆到热液演化过程中同源固相与流体相之间的平衡控制过程,以及成矿元素的溶解和富集行为:(1)岩浆‒热液过渡阶段形成的“羽丝状”含铜细晶岩脉群,表明在较高的温度(523~613)℃条件下,熔体和流体存在相分离;(2)岩浆‒热液过渡阶段形成的熔流体混合相是亲铜元素由岩浆迁移进入热液的保障,可能代表了运移成矿元素介质的性质;(3)在岩浆‒热液过渡阶段,晶洞中石英的阴极发光(CL)图像揭示了多期环带结构,不同环带的O同位素均显示来源于岩浆阶段,可能与同一岩浆房中存在成矿流体多次出溶相关;(4)岩浆‒热液过渡阶段分离出的碱性金属元素/挥发性组分(如H2O、F、B和Cl)进一步促进了伟晶岩型矿床中Li、Be等成矿金属的富集和迁移;(5)岩浆‒热液过渡阶段形成的特殊含矿结构(如文象结构)是伟晶岩型Be矿床的有效找矿标志。在岩浆‒热液过渡阶段形成的岩石学证据虽然受到后续热液的强烈改造,但是仍能保存部分重要的成矿学信息,剖析该阶段成矿作用有助于了解花岗质成矿岩浆完整的岩浆‒热液流体的演化过程。

关键词：岩浆‒热液型矿床战略性关键金属铜、锂、铍岩浆‒热液过渡阶段