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Encoding and Multiplexing of 2D Images with Orbital Angular Momentum Beams and the Use for Multiview Color Displays

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Research 2019年第1期2019卷 1144-1154页

作者： j.chu D.chu Q.Smithwick Centre for Photonics Devices and Sensors University of Cambridge9 JJ Tomson AvenueCambridge CB30FAUK Disney Research GlendaleCalifornia 91201-5020USA

Te orthogonal nature of diferent orbital angular momentum modes enables information transmission in optical communications with increased bandwidth through mode division multiplexing.So far the related works have been focused on using orbital angular momentum modes to encode/decode and multiplex point-based on-axis signals for maximum data channel numbers and capacity.Whether orbital angular momentum modes can be utilized to encode/decode of-axis signals for multiplexing in twodimensional space is of signifcant importance both fundamentally and practically for its enormous potential in increasing the channel information capacity.In this work,a direct use of orbital angular momentum modes to encode/decode and multiplex twodimensional images is realized in a scalable multiview display architecture,which can be utilized for viewing three-dimensional images from diferent angles.Te efect of of-axis encoding/decoding and the resultant crosstalk between multiplexed diferent twodimensional views are studied.Based on which,a color display of good image quality with four independent views is demonstrated.Te resolution of the decoded images is analyzed and the limitation of this approach discussed.Moreover,a spatially multiplexed data communication scheme is also proposed with such a two-dimensional encoding/decoding approach to signifcantly enhance the data transmission capacity in free space for future data communication needs.

关键词： orbital momentum utilized

Motor cortical circuit adaptations in parkinsonism

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Neural Regeneration Research 2024年第10期19卷 2107-2108页

作者： Hong-Yuan chu Department of Neurodegenerative Science Van Andel Research InstituteGrand RapidsMIUSA Aligning Science Across Parkinson’s(ASAP)Collaborative Research Network

Parkinson's disease is a chronic and progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta,which leads to the featured motor impairment of parki... 详细信息

关键词： parkin impairment rigidity

Novel data-driven sparse polynomial chaos and analysis of covariance for aerodynamics of compressor cascades with dependent geometric uncertainties

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Chinese journal of Aeronautics 2024年第6期37卷 89-108页

作者： Zhengtao GUO Wuli chu Haoguang ZHANG Tianyuan jI School of Power and Energy Northwestern Polytechnical UniversityXi’an 710072China

Polynomial Chaos Expansion(PCE)has gained significant popularity among engineers across various engineering disciplines for uncertainty analysis.However,traditional PCE suffers from two major drawbacks.First,the orthogonality of polynomial basis functions holds only for independent input variables,limiting the model’s ability to propagate uncertainty in dependent variables.Second,PCE encounters the"curse of dimensionality"due to the high computational cost of training the model with numerous polynomial coefficients.In practical manufacturing,compressor blades are subject to machining precision limitations,leading to deviations from their ideal geometric shapes.These deviations require a large number of geometric parameters to describe,and exhibit significant correlations.To efficiently quantify the impact of high-dimensional dependent geometric deviations on the aerodynamic performance of compressor blades,this paper firstly introduces a novel approach called Data-driven Sparse PCE(DSPCE).The proposed method addresses the aforementioned challenges by employing a decorrelation algorithm to directly create multivariate basis functions,accommodating both independent and dependent random variables.Furthermore,the method utilizes an iterative Diffeomorphic Modulation under Observable Response Preserving Homotopy regression algorithm to solve the unknown coefficients,achieving model sparsity while maintaining fitting accuracy.Then,the study investigates the simultaneous effects of seven dependent geometric deviations on the aerodynamics of a high subsonic compressor cascade by using the DSPCE method proposed and sensitivity analysis of covariance.The joint distribution of the dependent geometric deviations is determined using Quantile-Quantile plots and normal copula functions based on finite measurement data.The results demonstrate that the correlations between geometric deviations significantly impact the variance of aerodynamic performance and the flow field.Therefore,it is crucial to consider these correlations for

关键词： Data-driven sparse polyno-mial chaos Analysis of covariance Dependent uncertainty Aerodynamic performance Compressor cascade

Greatly enhanced corrosion/wear resistances of epoxy coating for Mg alloy through a synergistic effect between functionalized graphene and insulated blocking layer

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journal of Magnesium and Alloys 2024年第1期12卷 332-344页

作者： Z.Y.Xue X.j.Li j.H.chu M.M.Li D.N.Zou L.B.Tong School of Metallurgical Engineering Xi’an University of Architecture and TechnologyXi’an 710055China State Key Laboratory of Advanced Design and Manufacturing for Vehicle Body Hunan UniversityChangsha 410082China

The poor corrosion and wear resistances of Mg alloys seriously limit their potential applications in various industries.The conventional epoxy coating easily forms many intrinsic defects during the solidification process,which cannot provide sufficient protection.In the current study,we design a double-layer epoxy composite coating on Mg alloy with enhanced anti-corrosion/wear properties,via the spin-assisted assembly technique.The outer layer is functionalized graphene(FG)in waterborne epoxy resin(WEP)and the inner layer is Ce-based conversion(Ce)film.The FG sheets can be homogeneously dispersed within the epoxy matrix to fill the intrinsic defects and improve the barrier capability.The Ce film connects the outer layer with the substrate,showing the transition effect.The corrosion rate of Ce/WEP/FG composite coating is 2131 times lower than that of bare Mg alloy,and the wear rate is decreased by~90%.The improved corrosion resistance is attributed to the labyrinth effect(hindering the penetration of corrosive medium)and the obstruction of galvanic coupling behavior.The synergistic effect derived from the FG sheet and blocking layer exhibits great potential in realizing the improvement of multi-functional integration,which will open up a new avenue for the development of novel composite protection coatings of Mg alloys.

关键词： Mg alloy Functionalized graphene Epoxy coating Corrosion/wear resistance Blocking layer

Si-Miao-Yong-An Decoction alleviates thromboangiitis obliterans by regulating miR-548j-5p/IL-17A signaling pathway

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Chinese journal of Natural Medicines 2024年第6期22卷 541-553页

作者： chu chu SUN Shangwen ZHANG Zhen WU Qi LI Haoyang LIANG Gang MIAO Xiuming jIANG Haiqiang GAO Yan ZHANG Yunhong WANG Bin LI Xia Innovative Institute of Chinese Medicine and Pharmacy Shandong University of Traditional Chinese MedicineJinan 250355China National Key Laboratory for Innovation and Transformation of Luobing Theory The Key Laboratory of Cardiovascular Remod-eling and Function ResearchChinese Ministry of EducationChinese National Health Commission and Chinese Academy of Medical SciencesDepartment of CardiologyQilu Hospital of Shandong UniversityJinan 250012China School of Clinical and Basic Medical Sciences Shandong First Medical University&Shandong Academy of Medical SciencesJinan 271016China Affiliated Hospital of Shandong University of Traditional Chinese Medicine Jinan 250014China International Business School Tianjin Foreign Studies UniversityTianjin 300204China Institute of Pharmaceutical Research Shandong University of Traditional Chinese MedicineJinan 250355China

Thromboangiitis obliterans(TAO)is a rare,chronic,progressive,and segmental inflammatory disease characterized by a high rate of amputation,significantly compromising the quality of life of patients.Si-Miao-Yong-An decoction(SMYA),a tradition-al prescription,exhibits anti-inflammatory,anti-thrombotic,and various other pharmacological properties.Clinically,it was fully proved to be effective for TAO therapy,but the specific therapeutic effect of SMYA on TAO has been unknown.Thus,deep unveiling the mechanism of SMYA in TAO for identifying clinical therapeutic targets is extremely important.In this study,we observed elev-ated levels of IL-17A in the peripheral blood mononuclear cells(PBMCs)of TAO patients,whereas the expression of miR-548j-5p was significantly decreased.A negative correlation between the levels of miR-548j-5p and IL-17A was also demonstrated.In vitro ex-periments showed that overexpression of miR-548j-5p led to a decrease in IL-17A levels,whereas downregulation of miR-548j-5p showed the opposite effect.Using a dual luciferase assay,we confirmed that miR-548j-5p directly targets IL-17A.Furthermore,serum containing SMYA effectively decreased IL-17A levels by increasing the expression of miR-548j-5p.More importantly,the results of in vivo tests indicated that SMYA mitigated the development of TAO by inhibiting IL-17A through the upregulation of miR-548j-5p in vascular tissues.In conclusion,SMYA significantly enhances the expression of miR-548j-5p,thereby reducing the levels of the target gene IL-17A and alleviating TAO.Our research not only identifies novel targets and pathways for the clinical diagnosis and treatment of TAO but also advances the innovation in traditional Chinese medicine through the elucidation of the SMYA/miR-548j-5p/IL-17A regulatory axis in the pathogenesis of TAO.

关键词： Thromboangiitis obliterans IL-17A Inflammation miR-548j-5p Si-Miao-Yong-An Decoction

MAKING DUCTILE CAST IRON WITH ESR PROCESS

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Acta Metallurgica Sinica(English Letters) 1998年第3期11卷 169-174页

作者： S.j.chu H.H.Lou Q.Niu Univ of Science and Technology Beijing Beijing China

Making ductile cast iron with ESR process under D.C. condition without adding spheroidizing inoculant alloys has been studied in laboratory. The key operation of ESR for cast iron is increasing the silicon content in unrefined consumable electrodes of flake graphite cast iron and using CaF2-based slags containing rare-earth or basic oxides and magnesium fluoride. The samples excel ductile cast iron produced by general technological process in fatigue strength and sealing performance.

关键词： ductile cast iron electroslag remelting nodulizing element

BMSC-derived Exosomes Ameliorate Peritoneal Dialysis-associated Peritoneal Fibrosis via the Mir-27a-3p/TP53 Pathway

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Current Medical Science 2024年第2期44卷 333-345页

作者： jun-li ZHAO Lin ZHAO Qiu-nan ZHAN Miao LIU Ting ZHANG Wen-wen chu Department of Nephrology Shanghai University of Medicine&Health Sciences Ailiated Zhoupu HospitalShanghai 201318China Orthopedic Department Guangming Traditional Chinese Medicine Hospital of Pudong New AreaShanghai 201399China

Objective:Peritoneal fibrosis(PF)is the main cause of declining efficiency and ultrafiltration failure of the peritoneum,which restricts the long-term application of peritoneal dialysis(PD).This study aimed to investigate the therapeutic effects and mechanisms of bone marrow mesenchymal stem cells-derived exosomes(BMSC-Exos)on PF in response to PD.Methods:Small RNA sequencing analysis of BMSC-Exos was performed by second-generation sequencing.C57BL/6j mice were infused with 4.25%glucose-based peritoneal dialysis fluid(PDF)for 6 consecutive weeks to establish a PF model.A total of 36 mice were randomly divided into 6 groups:control group,1.5%PDF group,2.5%PDF group,4.25%PDF group,BMSC-Exos treatment group,and BMSC-Exos+TP53 treatment group.Reverse transcription quantitative polymerase chain reaction(RT-qPCR)was performed to measure the expression level of miR-27a-3p in BMSC-Exos and peritoneum of mice treated with different concentrations of PDF.HE and Masson staining were performed to evaluate the extent of PF.The therapeutic potential of BMSC-Exos for PF was examined through pathological examination,RT-qPCR,Western blotting,and peritoneal function analyses.Epithelial-mesenchymal transition(EMT)of HMrSV5 was induced with 4.25%PDF.Cells were divided into control group,4.25%PDF group,BMSC-Exos treatment group,and BMSC-Exos+TP53 treatment group.Cell Counting Kit-8 assay was used to measure cell viability,and transwell migration assay was used to verify the capacity of BMSC-Exos to inhibit EMT in HMrSV5 cells.Results:Small RNA sequencing analysis showed that miR-27a-3p was highly expressed in BMSC-derived exosomes compared to BMSCs.The RT-qPCR results showed that the expression of miR-27a-3p was upregulated in BMSC-Exos,but decreased in PD mice.We found that PF was glucose concentration-dependently enhanced in the peritoneum of the PD mice.Compared with the control mice,the PD mice showed high solute transport and decreased ultrafiltration volume as well as an obvious fibroproliferative response,with markedly increas

关键词： peritoneal fibrosis bone marrow mesenchymal stem cell-derived exosomes miR-27a-3p TP53 epithelialmesenchymal transition

Resource Allocation to Minimize the Makespan with Multi-Resource Operations

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journal of Systems Science & Complexity 2024年第5期 2054-2070页

作者： WENG Wuyan chu Chengbin WU Peng School of Economics and Management Fuzhou University Univ Gustave Eiffel ESIEE Paris&COSYS-GRETTIA

This paper investigates a new resource-allocation problem involving multi-resource operations, where completing an operation requires simultaneous use of multiple(renewable) resources,probably of different types. The goal of the study is to provide a solution method that minimizes the makespan. The authors formulate the problem into a novel mixed-integer linear program(MILP)model. To efficiently solve practical-sized instances, an exact Benders decomposition algorithm is developed. This algorithm divides the original problem into a master problem of allocating resources and a subproblem of calculating the makespan, and both are linked via Benders cuts. The convergence is sped up by improving the mathematical model and embedding the variable neighborhood search algorithm. Compared with CPLEX, a commonly used MILP solver, the computational results demonstrate that the proposed algorithm provides tighter upper and lower bounds in most instances. In particular,compared with CPLEX, the proposed method can on average improve the upper and lower bounds by 4.76% and 4.39%, respectively, in solving practical-sized instances.

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Winter extreme precipitation over the Tibetan Plateau influenced by Arctic sea ice on interdecadal timescale

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Advances in Climate Change Research 2024年第1期15卷 42-51页

作者： Qing-Quan LI Miao BI Song YANG Qing-Yuan WU Yi-Hui DING Xin-Yong SHEN Xiao-Ting SUN Meng-chu ZHAO China Meteorological Administration Key Laboratory for Climate Prediction Studies National Climate CentreBeijing 100081China Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science and TechnologyNanjing 210044China CMA Key Open Laboratory of Transforming Climate Resources to Economy Chongqing Institute of Meteorological SciencesChongqing 401147China School of Atmospheric Sciences and Guangdong Province Key Laboratory for Climate Change and Natural Disaster Studies Sun Yat-sen University Zhuhai 519082China Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) Zhuhai 519082China

The Tibetan Plateau(TP)and the Arctic are the most sensitive regions to global climate change.However,the interdecadal varibility of winter extreme precipitation over the TP and its linkage with Arctic sea ice are still unclear.In this study,the characteristics and mechisnems of the TP extreme precipitation(TPEP)influenced by Arctic sea ice on interdecadal timescale are studied based on the daily precipitation,monthly sea ice concentration and ERA5 reanalysis data from 1980 to 2018.We found that the dominant mode of the TPEP in winter mostly exhibits a uniform spatial variation on the interdecadal timescale,with an opposite weak variation in the southeastern TP,and the Arctic sea ice concentration(SIC)before 2002 are larger than that after 2003.The interdecadal variation of TPEP is affected by two teleconnection wave trains regulated by the Barents and Kara Sea ice.In the light ice years,a remarkable positive geopotential height(HGT)anomaly appears over the Barents-Kara Sea and a remarkable negative HGT anomaly is located over the Lake Baikal.Two wave trains originating over the Barents-Kara Sea can be observed.The southern branch forms a wave train through the North Atlantic along the subtropical westerly jet stream,showing a‘+-+-+'pattern of HGT anomalies from Arctic to the TP.Negative HGT anomaly controls the western TP,which creates dynamic and water vapor conditions for the TPEP.The northern branch forms a wave train through the Lake Baikal and the southeast of the TP,showing a‘+-+'HGT anomaly distribution.Positive HGT anomaly controls the southeastern TP,which is not conducive to precipitation in the region.When the SIC in the Barents-Kara Sea increases,the situation is opposite.The above analysis also reveals the reason for the difference in the east-west distribution of the TPEP.

关键词： Arctic sea ice Tibetan Plateau Winter extreme precipitation Rossby wave activity Interdecadal variation