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Signals and noise in the octavolateralis systems: What is the impact of human activities on fish sensory function?

Integrative Zoology 2015年第1期10卷 4-14页

作者： christopher b.bRAUN Department of Psychology Hunter CollegeCity University of New YorkNew YorkNYUSA

The octavolateralis systems of fishes include the vestibular,auditory,lateral line and electrosensory *** are united by common developmental and neuro-computational features,including hair cell sensors and computations based on cross-neuron analyses of differential hair cell stimulation *** systems also all use both spectral and temporal filters to separate signals from each other and from noise,and the distributed senses(lateral line and electroreception)add spatial filters as *** all sensory systems,these sensors must provide the animal with guidance for adaptive behavior within a sensory scene composed of multiple stimuli and varying levels of ambient noise,including that created by human *** the extreme,anthropogenic activities impact the octavolateralis systems by destroying or degrading the habitats that provide ecological resources and sensory *** slightly lesser levels of effect,anthropogenic pollutants can be damaging to fish tissues,with sensory organs often the most *** exposed sensory cells of the lateral line and electrosensory systems are especially sensitive to aquatic *** still lesser levels of impact,anthropogenic activities can act as both acute and chronic stressors,activating hormonal changes that may affect behavioral and sensory ***,human activities are now a nearly ubiquitous presence in aquatic habitats,often with no obvious effects on the animals exposed to *** noise,indigenous and industrial fishing techniques,and all the ancillary noises of human civilization form a major part of the soundscape of *** fish use these new sources of information about their habitat is a new and burgeoning field of study.

关键词： audition,electrosense lateral line soundscape underwater noise

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SARS-CoV-2:the many pros of targeting PLpro

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Signal Transduction and Targeted Therapy 2020年第1期5卷 633-634页

作者： christopher b.McClain Nicolas Vabret Department of Medicine Hematology and Medical OncologyIcahn School of Medicine at Mount SinaiNew YorkNYUSA Precision Immunology Institute Icahn School of Medicine at Mount SinaiNew YorkNYUSA

A new study1 published in Nature compares the mechanisms used by SARS-CoV-1 and SARS-CoV-2 papain-like protease(PLpro)to promote innate immune *** findings identify SARS-CoV-2 PLpro as an attractive drug target for tr... 详细信息

关键词： attractive finding Nature

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In the forest vine Smilax rotundifolia,fungal epiphytes show site-wide spatial correlation,while endophytes show evidence of niche partitioning

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Fungal Diversity 2015年第6期75卷 279-297页

作者： christopher b.Zambell James F.White Graduate Program in Ecology&Evolution Rutgers UniversityNew BrunswickNJ 08901USA Department of Plant biology&Pathology 59 Dudley RoadNew BrunswickNJ 08901USA

Endophytic and epiphytic fungal assemblages from stems of ***,a shrubby vine,were studied in order to(1)quantify differences and the degree of overlap between fungal communities of both micro-habitats,and(2)examine whether fungal assemblages are spatially correlated at the local scale(tens to hundreds of meters),in order to understand if dispersal limitation may play a role in structuring these *** was conducted over 160 m of growth along a forest *** communities showed low overlap(bray-Curtis Similarity=0.22),with most species that were common in one habitat appearing rarely if at all in the other,and only Aureobasidium pullulans showing high frequency in *** assemblages proved to be spatially correlated along the 160 m length of the transect,and even more so when adjacent pairs of stems were considered as the unit of comparison rather than individual *** assemblages showed no significant spatial correlation along the ***,three species of endophytes showed a pattern in which abundance of colonies peaked at different heights on the *** boninense showed peak abundance at 3 cm from the stem *** sp.1 peaked at 33 cm from the stem *** isolates of *** peaked at 63 cm from the stem *** was also found that positive correlative relationships were detected between endophyte-endophyte,and epiphyte-epiphyte ***-group interactions seemed to center around crossover species that were not entirely constrained within the surface or interior.

关键词： Colletotrichum Phomopsis Phyllosticta Local dispersal Tissue preference

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Variations in zonal fruit starch concentrations of apples – a developmental phenomenon or an indication of ripening?

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Horticulture Research 2015年第1期2卷 84-92页

作者： Franziska C Doerflinger William b Miller Jacqueline F Nock christopher b Watkins Horticulture Section School of Integrative Plant ScienceCornell UniversityIthaca14853NYUSA School of Agriculture Food&WineUniversity of AdelaideWaite CampusGlen Osmond5064South AustraliaAustralia

Patterns of starch hydrolysis in stem,equatorial,and calyx zones of‘Honeycrisp’and‘Empire’apples(Malus sylvestris(L.)Mill ***(borkh.)Mansf.)during maturation and ripening,and in‘Gala’apples in response to propylene or 1-methylcyclopropene(1-MCP)treatments after harvest,were *** in zonal starch concentrations were found for‘Empire’and‘Gala’fruits,but not for‘Honeycrisp’.During maturation and ripening of‘Empire’,the concentration of starch was highest in the calyx end and lowest in the stem region.Differences in rates of starch hydrolysis among zones were not detected.‘Honeycrisp’and‘Empire’had the highest concentration of sorbitol in the calyx region,whereas it was highest in the stem-end region in‘Gala’.The distribution differences of glucose,fructose,and sucrose were similar in all three cultivars;higher fructose and glucose concentrations in the stem region,and higher sucrose concentrations in the calyx end of the *** treatment of‘Gala’with propylene did not affect the internal ethylene concentration of the fruit but 1-MCP markedly inhibited *** concentrations were highest in the calyx end but gradients of starch among zones were not changed by postharvest *** rate of hydrolysis was slowed by 1-MCP treatment,but was unaffected by *** treatments influenced sorbitol,glucose,and fructose *** of starch concentration among the zones did not confirm differences in ripening,but reflected its uneven distribution throughout the fruit during ***,measured differences in zonal starch are most likely related to starch accumulation during fruit development,rather than differences in rates of starch degradation during ripening.

关键词： cultivar fir starch

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Release of unwanted flat-bodied fish from a horizontal-bar grid system as revealed through comparative fishing trials and underwater video observations

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Aquaculture and Fisheries 2021年第4期6卷 348-358页

作者： christopher b.Rillahan Pingguo He School for Marine Science and Technology University of Massachusetts Dartmouth836 South Rodney French BoulevardNew BedfordMA02744USA

Grid systems separate fish species primarily through physical means:fish size and body *** Georges bank off the northeast USA,many species of flounders are overfished,and their catch needs to be ***-bodied skates are also often *** tested a European style horizontal-bar grid system to reduce these flat-bodied low quota species in a trawl targeting the haddock(Melanogrammus aeglefinus),whose population is *** grid system consisted of 4 grid sections,two on each side,with horizontal bars 70 mm *** alternating tow method was used to compare the catch characteristics between a trawl with a grid section and the same trawl without a grid section.A video camera was used to observe fish escape in the grid *** results indicate that the grid system reduced the flounder catch rate(mainly winter flounder,Pseudopleuronectes americanus)by 51.3%,and skates(mainly winter skate,Leucoraja ocellata and little skate,Leucoraja erinacea)by 29.4%,while there were no differences in the catch of Atlantic cod(Gadus morhua).While haddock was reduced by 37%by weight,the reduction was primarily small undersized *** was no reduction in large haddock greater than 50 *** observations indicates that flounders and cod mainly escaped from the bottom half of the grid while haddock were from the top *** finding suggest that this system reduced low quota flounders,as well as discarded skates and small haddock,while retaining Atlantic cod and large size *** observations indicate that differential spacing(narrower on the top and wider on the bottom)may improve the system performance by releasing more flat-bodied fish,that were observed to escape from the bottom part of the grid,while retaining more haddock,which typically escape from the top part of the grid.

关键词： Trawl bycatch Selectivity Flounder Skate Haddock Atlantic cod

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Understanding development and ripening of fruit crops in an‘omics’ era

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Horticulture Research 2014年第1期1卷 157-166页

作者： Nigel E Gapper James J Giovannoni christopher b Watkins Department of Horticulture Cornell UniversityIthacaNY 14853USA boyce Thompson Institute for Plant Research Cornell UniversityIthacaNY 14853USA Plant Soiland Nutrition LaboratoryUS Department of Agriculture/Agriculture Research ServiceIthacaNY 14853USA

Next generation sequencing has revolutionized plant *** only has our understanding of plant metabolism advanced using model systems and modern chromatography,but application of‘omics’-based technology has been widely extended to non-model systems as costs have plummeted and efficiency *** a result,important fundamental questions relating to important horticultural crops are being answered,and novel approaches with application to industry are in *** we review recent research advances on development and ripening of fruit crops,how next generation sequencing approaches are driving this advance and the emerging future landscape.

关键词： crops driving metabolism

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Technical comments on rodent spinal cord injuries models

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Neural Regeneration Research 2014年第5期9卷 453-455页

作者： Zoe Zhang Yi Ping Zhang Lisa b.E.Shields christopher b.Shields Department of Neurosurgery University of Minnesota Norton Neuroscience Institute Norton Healthcare

Spinal cord injuries （SCI） in rodents have been created by laceration, contusion, compression, or intramedullary injection of toxic agents. The choice of an appropriate SCI model should be made for each study based on the experimental design, with care taken to avoid unintended complications such as hemorrhage. Technical comments will be made in this communication describing the 1） importance of vertebral stabi- lization, 2） injury preparation, and 3） landmarks to improve the preci- sion and reproducibility of the SCI.

关键词： SCI Technical comments on rodent spinal cord injuries models LISA Zhang

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Using Periodic Dynamic Polymers to Form Supramolecular Nanostructures

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Accounts of Materials Research 2022年第9期3卷 948-959页

作者： christopher b.Cooper Zhenan bao Department of Chemical Engineering Stanford UniversityStanfordCalifornia 94305United States

CONSPECTUS:Many emerging applications including wearable electronics and e-skins,soft robotics and actuators,and biomaterials require material platforms with precisely controlled mechanical,electrical,thermal,and optical *** practical realization of devices for these applications is often restricted not by the lack of novel designs but rather by the sparsity of materials with the required *** polymers,which employ both covalent and noncovalent linkages,offer a promising platform for the design of new materials because of their highly tunable chemical structures.

关键词： properties Dynamic realization

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Efficacy of adjuvant mitomycin-C and triamcinoloneimpregnated nasal packing for endoscopic dacryocystorhinostomy

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International Journal of Ophthalmology(English edition) 2024年第3期17卷 480-484页

作者： Sang Yoon Kim christopher b Chambers Jung Hyo Ahn Department of Ophthalmology Pusan National University Yangsan HospitalPusan National University School of MedicineResearch Institute for Convergence of Biomedical Science and TechnologyYangsanGyeongnam 50612Republic of Korea Department of Ophthalmology Harborview Medical CenterUniversity of Washington MedicineSeattleWashington 98109USA

●AIM:To compare the success rate and complications of adjuvant use of mitomycin C and triamcinoloneimpregnated biodegradable nasal packing(TAbP)in endoscopic dacryocystorhinostomy(DCR).And to evaluate the efficacy of combining intraoperative mitomycin C and TAbP for endoscopic DCR.●METHODS:A total of 198 eyes of 148 patients who underwent endoscopic DCR for acquired nasolacrimal duct obstruction were retrospectively *** patients were randomly divided into three groups:Group A included patients treated without intraoperative mitomycin C but with TAbP,Group b included patients treated without triamcinolone but with intraoperative mitomycin C and normal saline-impregnated nasal packing,and Group C included patients treated with intraoperative mitomycin C and TAbP.●RESULTS:The results revealed no significant difference in the overall success rates between Groups A(86.8%)and b(89.2%;P=0.377).However,Group C(97.5%)showed a significantly higher overall success rate than Groups A and *** incidence of granulomas was significantly lower in group C(5%)than in Groups A(20.8%)and b(15.2%;P=0.009).Other complications,such as crust,synechiae,and revision surgery,did not differ significantly among the three groups.●CONCLUSION:The combination of intraoperative mitomycin C and TAbP effectively prevents granulomas and enhances surgical success ***,there is no statistically significant difference observed between the use of mitomycin C or TAbP alone.

关键词： dacryocystorhinostomy endoscopic mitomycin C triamcinolone biodegradable

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Trends in ophthalmology journals： a five-year bibliometric analysis （2009-2013）

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International Journal of Ophthalmology(English edition) 2016年第11期9卷 1669-1675页

作者： christopher b.Schulz Alasdair Kennedy ben C.Rymer Eye Unit Royal Bournemouth Hospital Bournemouth BH77DW 15I( Department of Ophthalmology Conquest Hospital St.Leonards-on-Sea TN37 7RD UK Department of Plastic Surgery Queen Elizabeth HospitalBirmingham B15 2TH UK

AIM： To explore the trends in the ophthalmic literature over a 5-year period in relation to country, research expenditure and demographics. METHODS： Articles published between 2009 and 2013 by the 20 highest-contributing countries in the 20 top- ranked ophthalmology journals were identified by their country of affiliation. The number of articles published and mean impact factor were measured per country for each year and trends explored using regression analysis with 5-year and 10-year forecasts calculated. Data on research expenditure was collected and tested for correlation with the number of articles and mean impact factor. RESULTS： The analysis included 19 338 articles. The USA, UK and Europe accounted for 60.2% of articles published, with the USA contributing 7388 articles （34.0%）. The USA also demonstrated the highest mean impact factor （3.5）. Research expenditure was significantly correlated with both research output （r=0,86, P〈0.001） and scholarly impact （r=0.42, P〈0.001）. China （P〈0.01）, Korea （P〈0.01） and India （P〈0.02） demonstrated a significant growth in research output over the study period. The research contribution of these three countries combined is forecasted to overtake that of Europe within ten years, with China expected to be the second-largest contributor within five years. These countries were also among those demonstrating the greatest growth in research expenditure. CONCLUSION： While the USA and European countries are major contributors of ophthalmic research, the productivity of some Asian countries is growing impressively. The contribution of China, Korea and Indiais forecasted to outweigh that of Europe by 2023. Research expenditure is highly correlated with research productivity and these trends reflect the differing economic priorities across the world.

关键词： bibliometrics ophthalmology journalimpact factor

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