Technical comments on rodent spinal cord injuries models

作     者：Zoe Zhang Yi Ping Zhang Lisa B.E.Shields Christopher B.Shields 

作者机构：Department of Neurosurgery University of Minnesota Norton Neuroscience InstituteNorton Healthcare 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2014年第9卷第5期

页      面：453-455页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

基　　金：Norton Healthcare for their ongoing support 

主　　题：SCI Technical comments on rodent spinal cord injuries models LISA Zhang 

摘      要：Spinal cord injuries （SCI） in rodents have been created by laceration, contusion, compression, or intramedullary injection of toxic agents. The choice of an appropriate SCI model should be made for each study based on the experimental design, with care taken to avoid unintended complications such as hemorrhage. Technical comments will be made in this communication describing the 1） importance of vertebral stabi- lization, 2） injury preparation, and 3） landmarks to improve the preci- sion and reproducibility of the SCI.