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Modelling of the elastoplastic behaviour of the bio-cemented soils using an extended Modified Cam Clay model

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第6期16卷 2184-2197页

作者： Xuerui Wang christian b.Silbermann Thomas Nagel Udo Nackenhorst Institute of Mechanics and Computational Mechanics Leibniz UniversitätHannoverAppelstr.9aHannover30167Germany Gesellschaft für Anlagen-und Reaktorsicherheit(GRS)gGmbH Theodor-Heuss-Straße 4Braunschweig38122Germany Geotechnical Institute Technische Universität BergakademieFreibergGustav-Zeuner-Str.1Freiberg09599Germany

An elastoplastic constitutive model based on the Modified Cam Clay(MCC)model is developed to describe the mechanical behaviour of soils cemented via microbially induced calcite precipitation(MICP).It considers the increase of the elastic stiffness,the change of the yield surface due to MICP cementation and the degradation of calcium carbonate bonds during ***,to capture the typical contraction-dilation transition in MICP soils,the original volumetric hardening rule in the MCC model is modified to a combined deviatoric and volumetric hardening *** model could reproduce a series of drained triaxial tests on MICP-treated soils with different calcium carbonate ***,we carry out a parametric study and observe numerical instability in some *** combination with an analytical analysis,our numerical modelling has identified the benefits and limitations of using MCCbased models in the simulation of MICP-cemented soils,leading to suggestions for further model development.

关键词： Microbially induced calcite precipitation(MICP) Elastoplasticity Modified cam clay(MCC) OpenGeoSys MFront Contraction-dilation transition

Experimental studies on the energy dissipation of bolted structures with frictional interfaces:A review

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Friction 2024年第8期12卷 1623-1654页

作者： Yongfeng WANG Yanhong MA Jie HONG Giuseppe b.ATTIATO christian M.FIRRONE School of Energy and Power Engineering Beihang UniversityBeijing 102206China Research Institute of Aero-Engine Beihang UniversityBeijing 102206China Politecnico di Torino Department of Mechanical and Aerospace EngineeringTorino 10139Italy

bolted joints play a more and more important role in the structure with lighter weight and heavier *** paper aims to provide an overview of different experimental approaches for the dynamic behavior of structures in the presence of bolted joints,especially the energy dissipation or damping at frictional *** comprehension of energy dissipation mechanisms due to friction is provided first,while the key parameters and the measurement techniques,such as the excitation force,the preload of the bolt,or the pressure at the interfaces,are briefly ***,the round-robin systems aim to measure the hysteresis parameters of the frictional joints under tangential loads are reviewed,summarizing the basic theory and the strategies to apply the excitation force or acquire the response in different testing *** by parameter identification strategies for bolted structures,the test rigs with one or more simplified bolted joints are summarized to give an insight into the understanding of typical characteristics of bolted structures,which are affected by the presence of *** complex test rigs hosting real-like or actual engineering structures with bolted lap or flange joints are also introduced to show the identification process of the dynamic characteristics of bolted connections employed in specific *** on the review paper,researchers can get the basic knowledge about the experimental systems of the bolted structures,especially several classical round robin systems,such as the Gaul resonator and widely used brake-Reußbeam *** can take advantage of this background for more creative and effective future studies,make more progress on the study of assembled structures and understand the influence of bolting frictional connections on the dynamic response better.

关键词： review study bolted joints frictional damping experimental rigs measurements

Degeneration of foundation cushion species induced by ecological constraints can cause massive changes in alpine plant communities

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Science China(Life Sciences) 2024年第4期67卷 789-802页

作者： Jianguo Chen Xufang Chen Lishen Qian Yazhou Zhang bo Li Honghua Shi Lu Sun christian Schöb Hang Sun Key Laboratory for Plant Diversity and biogeography of East Asia Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China University of Chinese Academy of Sciences Beijing 100049China College of Resources and Environment Yunnan Agricultural UniversityKunming 650500China Área de biodiversidad y Conservación Universidad Rey Juan CarlosMóstoles 28933Spain

Foundational cushion plants can re-organize community structures and sustain a prominent proportion of alpine biodiversity,but they are sensitive to climate *** loss of cushion species can have broad consequences for associated *** potential plant community changes with the population dynamics of cushion plants remain,however,*** eight plant communities along a climatic and community successional gradient,we assessed cushion population dynamics,the underlying ecological constraints and hence associated plant community changes in alpine communities dominated by the foundational cushion plant Arenaria *** population dynamics of Arenaria are attributed to ecological constraints at a series of life history *** functions are constrained by increasing associated beneficiary plants;subsequent seedling establishment is constrained by temperature,water and light availability,extreme climate events,and interspecific competition;strong competitive exclusion may accelerate mortality and degeneration of cushion *** with cushion dynamics,species composition,abundance and community structure gradually *** cushion plants completely degenerate,previously cushion-dominated communities shift to relatively stable communities that are overwhelmingly dominated by *** warming may accelerate the degeneration process of *** of this foundational cushion plant will possibly induce massive changes in alpine plant communities and hence ecosystem functions in alpine *** assessment of the population dynamics of foundation species is critical for an effective conservation of alpine biodiversity.

关键词： alpine ecosystem biodiversity change climate change plant community dynamics foundation species global warming population dynamics

Clustering of voltage-gated ion channels as an evolutionary trigger of myelin formation

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Neural Regeneration Research 2024年第8期19卷 1631-1632页

作者： Henrike Ohm Simone Rey christian Klambt Institut fur Neuro-und Verhaltensbiologie MunsterGermany

Neurons carry apical dendrites that perceive information and a basal axon that transmits the computed information towards its to *** axon originates at the axon hillock which is followed by the axon initial ***,action potentials are initiated that are based on millisecond long openings of specific voltagegated sodium and potassium channels that are conserved in all parahoxozoa(Placozoa,Cnidaria,bilateria)(Li et al.,2015).

关键词： initiated carry potassium

Risk predictors of post-hepatectomy liver failure: unraveling complexities and navigating challenges in clinical application

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Hepatobiliary Surgery and Nutrition 2024年第3期13卷 500-504页

作者： Marc-Anthony Chouillard christian Hobeika Département de Chirurgie Hépato-bilio-Pancréatique et de Transplantation Hépatique Hôpital BeaujonAP-HPUniversitéParis-CitéClichyFrance UMR Inserm 1275 CAP Paris-Tech Hôpital LariboisièreUniversitéParis-CitéParisFrance

Studies related to the prediction of post-hepatectomy liver failure(PHLF)have seen a surge in recent literature.A PubMed search using the terms((“pred*”OR“nomogra*”OR“model*”)AND(“mortality”OR“liver failure”OR“PHLF”)AND(“hepatect*”OR“liver resect*”))revealed 29 relevant studies on PHLF prediction between January 2020 and November 2023,with 20 adhering to grade b/C International Study Group of Liver Surgery(ISGLS)definitions(Table 1).These studies are primarily enrolling patients with hepatocellular carcinoma(HCC).This underscores the growing interest in applying such predictive scores in routine clinical ***,the extent to which these predictive models can be effectively implemented in clinical settings remains unclear(21,22).Indeed,all studies are retrospective,and only a limited number underwent external *** is crucial to recognize that these scores predominantly emerge within surgical cohorts,where patients underwent prior meticulous selection,leading to tailored surgical strategies and the exclusion of specific candidates(21).

关键词： Liver failure modeling prediction hepatectomy

Efficient removal of the recalcitrant metamizole contaminant from drinking water by using a CaLaCoO_(9) perovskite supported on recycled polyethylene

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Journal of Environmental Sciences 2024年第2期136卷 56-67页

作者： Ernesto Valadez-Renteria christian Perez-Carrasco Dulce Yolotzin Medina-Velazquez Vicente Rodriguez-Gonzalez Jorge Oliva CONACYT-División de Materiales Avanzados Instituto Potosino de Investigación Científica y Tecnológica A.C.San Luis PotosíSLP 78216México División de Ciencias básicas e Ingeniería Universidad Autónoma Metropolitana AzcapotzalcoCol.Reynosa-TamaulipasC.P.MéxicoDF 02200México

Metamizole(MZ)is a widely used anti-inflammatory *** to its common use,this contaminant is found in sewage and *** order to reduce the contamination produced by the MZ,we fabricated in this work a photocatalytic composite using recycled polyethylene(RPE)and the CaLaCoO_(9)(LCCO)*** nanoparticles had a microplate-like morphology and sizes of 1.4–5.5μm according to the analysis of *** photocatalytic properties of the LCCO powders were evaluated under ultraviolet-visible(UV-Vis)irradiation and found a removal efficiency of 96%.When the RPE+LCCO composite was employed for the photocatalytic degradation of MZ,a maximum degradation of 92.5%was *** influence of the pH on the photocatalytic activity was also studied and found that an initial pH=3 produced a total degradation of MZ after 240 min of UV-Vis ***,three reuse cycles were carried out for the pure LCCO powders and for the RPE+LCCO composites and found that the maximum loss of degradation was 5%.Furthermore,scavenger experiments demonstrated that the super oxide and hydroxyl radicals are formed during the photocatalytic reaction and were responsible for the degradation of ***,the X-ray photoelectron-spectroscopy and Raman analysis demonstrated the formation of defects(oxygen vacancies),those ones delayed the electron-hole recombination,which in turn,enhanced the degradation of the ***,the studies performed in this work proved that composites made with recycled plastics and LCCO perovskites are a low-cost and feasible alternative for the cleaning of water sources polluted with pharmaceutical compounds.

关键词： Photocatalysis Metamizole Pharmaceutical contaminant UV-Vis irradiation Perovskite

Unveiling ferroptosis as a promising therapeutic avenue for colorectal cancer and colitis treatment

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Acta Pharmaceutica Sinica b 2024年第9期14卷 3785-3801页

作者： Aaron T.Kaoy christian V.Cabanlongy Kendra Padilla Xiang Xue Department of biochemistry and Molecular biology University of New MexicoAlbuquerqueNM 87131USA

Ferroptosis is a novel type of regulated cell death(RCD)involving iron accumulation and lipid *** its discovery in 2012,various studies have shown that ferroptosis is associated with the pathogenesis of various *** cell death has also been linked to intestinal dysfunction but can act as either a positive or negative regulator of intestinal disease,depending on the cell type and disease *** continued investigation of mechanisms underlying ferroptosis provides a wealth of potential for developing novel *** the growing prevalence of intestinal diseases,particularly colorectal cancer(CRC)and inflammatory bowel disease(IbD),this review article focuses on potential therapeutics targeting the ferroptotic pathway in relation to CRC and IbD.

关键词： Ferroptosis Colorectal cancer Inflammatory bowel disease Cell death Molecular mechanisms Iron metabolism Drug therapies Targeted therapeutics

A Modified Lagrange Method for Solving Convex Quadratic Optimization Problems

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Open Journal of Optimization 2024年第1期13卷 1-20页

作者： Twum b. Stephen Avoka John christian J. Etwire School of Mathematical Science C. K. Tedam University of Technology and Applied Sciences Navrongo Ghana Department of Mathematics University for Development Studies Tamale Ghana

In this paper, a modified version of the Classical Lagrange Multiplier method is developed for convex quadratic optimization problems. The method, which is evolved from the first order derivative test for optimality of the Lagrangian function with respect to the primary variables of the problem, decomposes the solution process into two independent ones, in which the primary variables are solved for independently, and then the secondary variables, which are the Lagrange multipliers, are solved for, afterward. This is an innovation that leads to solving independently two simpler systems of equations involving the primary variables only, on one hand, and the secondary ones on the other. Solutions obtained for small sized problems (as preliminary test of the method) demonstrate that the new method is generally effective in producing the required solutions.

关键词： Quadratic Programming Lagrangian Function Lagrange Multipliers Optimality Conditions Subsidiary Equations Modified Lagrange Method

Enhanced diagnostic workup increases pathological findings in patients with acute ischaemic stroke:results of the prospective HEbRAS study

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Stroke & Vascular Neurology 2024年第2期9卷 145-152,I0414-I0425页

作者： Simon Hellwig Thomas Krause Jan F Scheitz Juliane Herm Ulrike Grittner Nadja Jauert Jochen b Fiebach Mario Kasner Wolfram Doehner Matthias Endres Rolf Wachter Thomas Elgeti christian H Nolte Karl Georg Haeusler Department of Neurology with Experimental Neurology Charité-Universitätsmedizin Berlincorporate member of Freie Universität Berlin and Humboldt-Universität zu BerlinBerlinGermany Center for Stroke Research berlin BerlinGermany berlin Institute of Health at Charité–Universitätsmedizin berlin BIH Biomedical Innovation AcademyBerlinGermany Department of Neurology Jüdisches Krankenhaus BerlinBerlinGermany German Center for Cardiovascular Diseases(DZHK) Partner Site BerlinBerlinGermany Institute of biometry and Clinical Epidemiology Charité-Universitätsmedizin BerlinBerlinGermany bIH Center for Regenerative Therapies(bCRT) Berlin Institute of Health at Charité–Universitätsmedizin BerlinBerlinGermany Department of Cardiology Charité-Universitätsmedizin BerlinBerlinGermany Department of Cardiology Campus Benjamin FranklinCharité-Universitätsmedizin BerlinBerlinGermany German Center for Neurodegenerative Diseases(DZNE) Partner Site BerlinBerlinGermany Department of Cardiology University Hospital LeipzigLeipzigGermany Department of Radiology Charité-Universitätsmedizin BerlinBerlinGermany Department of Neurology University Hospital WürzburgWürzburgGermany

background Stroke aetiology remains cryptogenic in a relevant proportion of patients with acute ischaemic stroke(AIS).We assessed whether enhanced diagnostic workup after AIS yields a higher rate of prespecified pathological findings compared with routine diagnostic care *** Hospitalised patients with AIS were prospectively enrolled in the investigator-initiated observational HEart and bRain Interfaces in Acute Ischaemic Stroke(HEbRAS)study at the Charité,berlin,*** with AIS without known atrial fibrillation(AF)underwent cardiovascular MR imaging(CMR),MR-angiography of the aortic arch and prolonged Holter-ECG monitoring on top of routine diagnostic *** Among 356 patients with AIS(mean age 66 years,37.6%female),enhanced workup yielded a higher rate of prespecified pathological findings compared with routine care(17.7%vs 5.3%;pber NCT02142413.

关键词： routine patients prospective