检索结果-南通市图书馆

2005年杭州药物代谢国际研讨会

作者： Xiao-hui Zheng Jian-bin Zheng Xin-feng Zhao Xin Zhao and Hong-bo Lu Institute of Analytical Science/ShaanXi Provincial Key Lab of Electroanalytical Chemistry Northwest University Xi’an ShaanXi china engineering and reasearch center of chinese herb modernization Xi’an Jaotong University Xi’an ShaanXi china

＜正＞A fast and valid solid phase extract-high performance liquid chromatography-trap mass spectrometry （SPE-HPLC-trap MS） method has been developed for quantitative determination of Danshensu and qualitative analy... 详细信息

关键词： Compound Danshen Dripping Pills Danshensu metabolites

Aspects of recent developments in analytical chemometrics

在线全文

cnki会议

学校读者我要写书评

暂无评论

Science china Chemistry 2006年第3期49卷 193-203页

作者： LIANG Yizeng1,2, WU Hailong1, SHEN Guoli1, JIANG Jianhui1, LIANG Sheng2 & YU Ruqin1 1. State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical engineering, Hunan University, Changsha 410082, china 2. Research center of modernization of Traditional chinese Medicines, Central South University, Changsha 410081, china 1. State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical Engineering Hunan University Changsha 410082 China 2. Research center of modernization of Traditional chinese Medicines Central South University Changsha 410081 China

Some aspects of recent developments in analytical chemometrics are discussed, in par- ticular the developments viewed from the angle of the research efforts undertaken in authors’ labora- tories. The topics concerned include resolution of high-order chemical data, morphological theory and methodology for chemical signal processing, multivariate calibration and chemical pattern recognition for solving complex chemical problems, and resolution of two-way chemical data from hyphenated chromatographic instruments.

关键词： chemometrics, high-order chemical data, pattern recognition, multivariate calibration and resolution.

Analysis of volatile oil in Rhizoma Ligustici Chuanxiong-Radix Paeoniae Rubra by gas chromatography-mass spectrometry and chemometric resolution

在线全文

学校读者我要写书评

暂无评论

Acta Pharmacologica Sinica 2006年第4期27卷 491-498页

作者： Xiao-ru LI Yi-zeng LIANG~2 Fang-qiu GUO College of Chemistry and Chemical engineering,Research center of modernization of Traditional chinese Medicines,Central South University,Changsha 410083.china CollegeofChemistryandChemicalengineering ResearchCenterofModernizationofTraditionalChineseMedicinesCentralSouthUniversityCha

Aim:To analyze the volatile chemical components of the herbal pair RhizomaLigustici Chuanxiong-Radix Paeoniae Rubra(RLC-RPR)and compare them withthose of each of the herbs ***:Gas chromatography-mass spectrom-etry(GC-MS),a chemometric resolution technique using the heuristic evolvinglatent projections(HELP)method,and the overall volume integration methodwere ***:In total,52,38,and 61 volatile chemical components in RLC,RPR,and RLC-RPR essential oils were determined,respectively,accounting for95.14%,95.19%,and 89.68% of the total contents of essential oil of RLC,RPR,andRLC-RPR,*** main volatile chemical components werebutyldienephthalide(20.65%)and ligustilide(50.15%)for RLC;and n-hexadecanoicacid(20.18%),[Z,Z]9,12-octadecadienoic acid(30.11%),2-hydroxy-benzaldehyde(17.08%)for RPR,and butyldienephthalide(14.80%),and ligustilide(38.91%)*** main volatile chemical components of RLC-RPR were almost thesame as those of RLC,but the relative amounts were ***:Thenumber of volatile chemical components in RLC-RPR was almost equal to the sumof the number in the 2 constituent herbs,but the relative amounts were ***,an acid-base reaction takes place during the process of decoctingthe *** data gathered in this study may be helpful for understanding thesynergistic nature of this herb pair in traditional chinese medicine.

关键词： herbal pair Rhizoma Ligustici Chuanxiong-Radix Paeoniae Rubra essential oil gas chromatography-mass spectrometry chemometric resolution method

A NOVEL 3D MOLECULAR SIMILARITY ALGORITHM BASED ON ENERGY SPECTRUM

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

A NOVEL 3D MOLECULAR SIMILARITY ALGORITHM BASED ON ENERGY SP...

40th IUPAC Congress

作者： Wei Liu Jun Xu Shuo Chen Yizeng Liang * Research center of modernization of Traditional chinese herb Medicine College of Chemistry and Chemical engineering Central South University Changsha 410083 china.

Multiple Description Coding Based On Multiwavelets Transforming

在线全文

cnki会议

学校读者我要写书评

暂无评论

Multiple Description Coding Based On Multiwavelets Transform...

2010 IEEE 2nd Symposium on Web Society

作者： Baobin Li School of Information Science and engineering Graduate University of chinese Academy of Sciences Beijing,100190,china Qing Ye china center for modernization Research chinese Academy of Science Beijing,100190,china

＜正＞Multiple description coding is a source coding for multiple channels such that a decoder which receives an arbitrary subset of the channels may produce a useful reconstruction,which is one of useful methods for solving the problem of packet losses in network *** this paper,on the basis of multiwavelet transform,a new method of multiple description coding will be presented,and experiments show it works ***,a parametrization of one kind of multifiler banks,which generate multiwavelets with some good properties,will be given.

关键词： Multiple description coding multiwavelet parametrization multifllter bank

在线全文

cnki会议

学校读者我要写书评

暂无评论

高效液相色谱法测定食物中的类胡萝卜素

色谱 2005年第1期23卷 57-62页

作者：卢红梅梁逸曾中南大学化学化工学院中药现代化研究中心湖南长沙410083

综述了用于食物中的类胡萝卜素、类胡萝卜素酯测定的高效液相色谱方法,介绍了样品提取处理方法、色谱分离条件及检测方法。引用文献85篇。

关键词：高效液相色谱法类胡萝卜素食物分析综述

Counter current chromatography numerical simulation

在线全文

学校读者我要写书评

暂无评论

Counter current chromatography numerical simulation

第十届全国计算(机)化学学术会议

作者： Zhaohui Yang,Bing Wang,Yizeng Liang (College of Chemistry and Chemical engineering,Research center of modernization of chinese Medicines, Central South University,Changsha,410083,People’s Republic of china,)

For measuring a certain solute’s concentration distribution in counter current chromatography tube,a numerical model was suggested for calculation of the retention volume (V) and simulation of ***-Stage ratio(RSR) was introduced to describe retention time;it has positive proportion to the retention time(RSR =(F/V)t,where F is the flow rate;V is the balance mobile phase volume;t is time.).RSR(RSR =[(1-S+ kS)/(1 - S)](1 -1/n), where S is the retention ratio of stationary phase,n is stages number.) is a constant for a specified k value for a large number of stages(k value is defined as the proportion of concentration in the stationary phase and mobile phase).For a certain material,the concentration distribution is a Negative Binomial(x= Cpqx,where x is the concentration for a solute which distribution ratio is k,x is the initial concentration,p=(1-S)/(1-S+kS), q = kS/(1-S+kS)).For some solvent system,the consumed time for the balance of the solvents is very long and the consumption of solvents is costly,solvents reuse became very important,especially for the balanced ***-feed is essential for such a time and money consumed *** numerical model can predict the optimal feed *** influence to the process for the amount of a feeding solute is discussed *** efficiency(E),which was defined as E = n/n(n is stages,which can be measured by the equation n=1/2πqX,where X is the dimensionless concentration.),was introduced to determine the effect to the spectrum by different k values of different components.

关键词： numerical model retention volume row-stage ratio negative binomial multi-feed stage efficiency

均匀设计在蚕蛹虫草和冬虫夏草活性成分分析中的应用

在线全文

cnki会议

学校读者我要写书评

暂无评论

分析测试学报 2004年第2期23卷 35-37,40页

作者：周枝凤梁逸曾胡芸郭方遒中南大学化学化工学院中药现代研究中心湖南长沙410083

采用均匀实验设计方法快速找到蚕蛹虫草活性成分的高效液相色谱最优分离条件 ;将该优化条件用于蚕蛹虫草和冬虫夏草的水溶性成分的分离取得满意结果 ,并对部分组分进行了定性定量分析 ;均匀实验设计方法可较快找到复杂未知或半未知体系... 详细信息

采用均匀实验设计方法快速找到蚕蛹虫草活性成分的高效液相色谱最优分离条件 ;将该优化条件用于蚕蛹虫草和冬虫夏草的水溶性成分的分离取得满意结果 ,并对部分组分进行了定性定量分析 ;均匀实验设计方法可较快找到复杂未知或半未知体系的色谱分离条件。

关键词：蚕蛹虫草冬虫夏草活性成分成分分析均匀设计高效液相色谱

在线全文

学校读者我要写书评

暂无评论

5种大黄蒽醌类衍生物的同时测定及应用

时珍国医国药 2009年第10期20卷 2490-2492页

作者：吕慧英赵晨曦梁逸曾吴海中南大学化学化工学院中药现代化研究中心湖南长沙410083 长沙大学生物工程与环境科学系湖南长沙410003

目的建立同时测定大黄药材中5种蒽醌类衍生物（芦荟大黄素、大黄酸、大黄素、大黄酚和大黄素甲醚）含量的方法,优化大黄蒽醌的超声提取工艺。方法采用反相高效液相法,色谱柱：W aters C18柱（250 mm×4.6 mm,5μm）;流动相：甲醇-乙腈-0... 详细信息

目的建立同时测定大黄药材中5种蒽醌类衍生物（芦荟大黄素、大黄酸、大黄素、大黄酚和大黄素甲醚）含量的方法,优化大黄蒽醌的超声提取工艺。方法采用反相高效液相法,色谱柱：W aters C18柱（250 mm×4.6 mm,5μm）;流动相：甲醇-乙腈-0.01%磷酸溶液（3∶5∶2）;柱温：25℃;流速：1.0 m l/m in;检测波长：225 nm。结果5种游离蒽醌均具有较宽的线性范围且呈良好的线性关系（R2=0.998 7～0.999 7）,平均回收率为92.79%～99.28%,日内精密度为0.65%～1.71%,日间精密度为2.52%～3.46%。结论该方法成功应用于大黄活性物质的提取工艺优化,根据所建立的方法测得的5种游离蒽醌含量,确定了大黄蒽醌的最佳超声提取工艺为：以70%乙醇为溶剂、料液比为1∶30（g∶m l）、超声提取2次、每次提取20 m in。

关键词：超声提取大黄 RP-HPLC 蒽醌

Interaction of Alisols and Hemoglobin using spectroscopic and molecular modeling methods

在线全文

学校读者我要写书评

暂无评论

Interaction of Alisols and Hemoglobin using spectroscopic an...

中药与天然药高峰论坛暨第十二届全国中药和天然药物学术研讨会

作者： Fei Xu~a,Lin-qun Zhang~(b,c),Wei Gu~a,Qi-nan Wu~(a,*) a Nanjing University of chinese Medicine,Nanjing 210046,china b School of Chemistry and Chemical engineering,Southeast University,Nanjing 210000,china c center for Analysis and Testing,Nanjing Normal University,Nanjing 210097,china

Alisols are the main pharmaceutical components of Alisma,a well known herb in Traditional chinese Medicine(TCM).This paper investigated the molecular interaction mechanism of Alisols and Hemoglobin(Hb)by using Fluorescence and Circular Dichroism spectra in combination with molecular modeling under the simulated physiological *** modeling results that were in agreement with the experimental results revealed that the binding of Alisol B 23-acetate and Hb was much more than that with Alisol A 24-acetate,indicating that the difference was related to the structure of the side chain of which the opened one leads to the strong binding while the folded to the weak so that the former may be the steering group of *** conclusion should be of great assistant for studying the clinical use of Alisma.

关键词： Alisol B 23-acetate Alisol A 24-acetate Fluorescence spectra Circular Dichroism spectra molecular modeling