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Global burden of lung cancer in 2022 and projected burden in 2050

中华医学杂志(英文版) 2024年第21期137卷 2577-2582页

作者： Guo Lanwei Zhu chenxin Cai Lin Zhang Xinglong Fang Yi Chen Hongda Yang Haiyan Department of Clinical Research Management The Affiliated Cancer Hospital of Zhengzhou University &amp Henan Cancer Hospital Zhengzhou Henan China Department of Epidemiology School of Public Health Zhengzhou University Zhengzhou Henan China Center for Prevention and Early Intervention National Infrastructures for Translational Medicine Institute of Clinical Medicine Peking Union Medical College Hospital Chinese Academy of Medical Sciences &amp Peking Union Medical College Beijing China

Background: Lung cancer is the most common cancer and a leading cause of cancer-related deaths globally. The aim of this study was to evaluate the incidence and mortality of lung cancer worldwide in 2022 and to project the number of new cases and deaths due to lung cancer in China and the United States in ***: In this study, data from the GLOBCAN 2022 database were used to analyze lung cancer incidence and mortality. The current status of lung cancer incidence and deaths was described by country/region, sex, age, and the human development index (HDI), and future lung cancer incidence and deaths in China and the United States were projected for ***: Globally, an estimated 2,480,675 new lung cancer cases and 1,817,469 lung cancer-related deaths occurred in 2022, with age-standardized incidence rates (ASIRs) and age-standardized mortality rates (ASMRs) of 23.6/100,000 and 16.8/100,000, respectively. In China, the ASIR and ASMR for male lung cancer patients were approximately 1.7 times and 2.7 times greater than those for female lung cancer patients, respectively. The ASIR and ASMR in high-HDI countries were approximately 8.5 times and 6.5 times those in low-HDI countries, respectively. It is estimated that in 2050, there will be approximately 1120 thousand new cases and 960 thousand deaths among Chinese men, 680 thousand new cases and 450 thousand deaths among Chinese women, approximately 170 thousand new cases and 110 thousand deaths among American men, and 160 thousand new cases and 90 thousand deaths among American ***: There are significant differences in the incidence and mortality of lung cancer among different regions and sexes. Therefore, sex factors need to be considered in the prevention, screening, and treatment strategies of lung cancer, and the implementation of tertiary prevention measures for lung cancer, especially primary and secondary prevention, needs to be actively promoted.

关键词： Lung neoplasm Incidence Mortality GLOBOCAN Females Early detection of cancer

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Structure and Combustion Characteristics of Methane/Air Premixed Flame under the Action of Wall

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Energy Engineering 2021年第4期118卷 1135-1154页

作者： Feiyang Li Jianfeng Pan chenxin Zhang Evans K.Quaye Xia Shao School of Energy and Power Engineering Jiangsu UniversityZhenjiang212013China

In order to obtain the combustion characteristics of the CH4/Air premixed flame under the action of the wall interaction,a study on the impact of the jet flame on the wall at different separation distances was carried *** separation distance from the burner outlet to the lower surface of the wall is changed and the flame structure is obtained through *** temperature,velocity and reaction rate are obtained through numerical simulation,and the law of flame characteristics change is obtained through *** results show that as the separation distance increases,the premixing cone inside the flame gradually changes from a horn shape to a complete cone shape and the length of the premixing cone profile ***,the peak temperature and velocity of the mixture in the axial direction gradually increase,and the temperature and velocity in the radial direction first increase and then *** temperature gradient and velocity reach the maximum when the separation distance is 11 *** peaks of reactants(CH_(4))net reaction rate intermediate products(CO)and products(CO_(2),H_(2)O)on the axis and the axial distance corresponding to the peaks increase *** chemical reaction rate near the wall also gradually decreases with the increase of the separation distance.

关键词： Flame-wall interaction separation distance flame structure air flow temperature flow velocity reaction rate

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数字化转型中的国际中文教育——历史趋势与未来展望

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世界华文教学 2024年第2期 55-68页

作者：王陈欣郑国锋彭丽华华东理工大学外国语学院上海外国语大学上海全球治理与区域国别研究院

在数字化转型背景下,学界对国际中文教育技术、教学设计和教师发展等议题展开了研究,但鲜有学者采用文献计量方法纵览该领域的发展历程,且相关热点分布、趋势、局限和空白的横向分析也有待深入。本研究运用CiteSpace软件对308篇相关文... 详细信息

在数字化转型背景下,学界对国际中文教育技术、教学设计和教师发展等议题展开了研究,但鲜有学者采用文献计量方法纵览该领域的发展历程,且相关热点分布、趋势、局限和空白的横向分析也有待深入。本研究运用CiteSpace软件对308篇相关文献进行了计量分析与可视化呈现,展现了该领域在过去20多年的螺旋式增长。研究热点主要涵盖数字教育规划、“数智”技术革新、智慧教学设计和教师数字素养等方面;研究方法以理论构建为主。未来的研究可尝试采用实证方法,加强对已构建理论的检验,同时可借鉴生态学视角,探究多层面因素对国际中文教育数字化转型过程的影响。

关键词：数字化转型国际中文教育计量分析

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WIND TUNNEL SIMULATION OF WIND EFFECT ON A GROUP OF HIGH COOLING TOWERS

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Acta Mechanica Sinica 1987年第1期3卷 36-43页

作者： Yan Dachun Li chenxin (Department of Mechanics,Peking University) Department of Mechanics Peking University Beijing China

Aerodynamic interference between high cooling towers in the atmospheric boundary layer(ABL) and uniform flow has been *** the 1/1000 ABL model set up in the 2.25m low speed windtunnel at Peking University,the similarity condition of the cooling tower in the ABL,the simulation resultsof a single tower and some typical tower groups have been *** showed that the Circum-ferential pressure distributions were consistent between the smooth model tower and the prototype tower,and between the rough model tower and the prototype tower with ribs;the two dimensional characteristics inthe circumferential pressure distribution were also noticeable around the middle 1/3 part of the tower afternondimensionalization by local dynamic *** demonstrate that,in the flow with strong turbul-ence the lift coefficient of the downstream cylinder approaches *** the flow with weak turbulence,thepressure distribution reflects a strong nonsymmetry,and the lift coefficient or stagnation pressure of thedownstream cylinder switches alternately between 1 and 0,where a concentrated vortex rolls up and thensheds toward the front of the downstream cylinder and exerts a decisive influence on the aerodynamicproperties of the downstream cylinder.

关键词： atmospheric boundary layer wind tunnel cooling tower

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Off-pump and on-pump coronary artery bypass surgery:reply to Dr. Shahzad G Raja

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Chinese Medical Journal 2004年第6期117卷 960-960页

作者： chenxin DepartmentofThoracicandCardiovascularSurgery NanjingFirstHospitalNanjingMedicalUniversityNanjing210006China

To the editor:We appreciate Dr. Shahzad's interest in our study and his comments regarding off-pump coronary bypass grafting.

关键词： bypass surgery coronary bypass grafting

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Effectiveness of E-SBIRT intervention in community healthcare institution in China:study proposal for a randomised controlled trial

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General Psychiatry 2021年第5期34卷 1-7页

作者： Rao Fu chenxin Yuan Wei Sun Wenzheng wang Lei Zhang Jing Zhai Qun Guan Xiaojun Wu Jiang Long Min Zhao Jiang Du Shanghai Mental Health Center Shanghai Jiao Tong University School of MedicineShanghaiChina Community Health Service Center of Jiangning Road ShanghaiChina Psychological Science Research Institute UniversitéCatholique de LouvainLouvain-la NeuveBelgium

Background Many studies have demonstrated the effectiveness of Screening,Brief Intervention and Referral to Treatment(SBIRT)in addressing substance use ***,owing to the shortage of counsellors,it has not been widely used in *** the development of smart medicine,we developed a web-based electronic SBIRT(E-SBIRT)program and explored the effectiveness of E-SBIRT in reducing substance use in *** A randomised controlled trial will be conducted in primary healthcare *** primary healthcare institutions will be selected and randomly divided into an intervention group and a control group(each institution will recruit 60 participants,and in total,240 participants will be recruited).The control group will get a pamphlet of drug abuse prevention,and the intervention group will get the E-SBIRT intervention and the *** groups will receive baseline and follow-up assessment at 1 and 3 months after the *** primary outcome is the change in scores on the Alcohol,Smoking and Substance Use Involvement Screening Test,and the secondary outcomes include changes in motivation,depression,anxiety,positive/negative emotion,self-esteem,addiction knowledge and addiction severity *** If the‘E-SBIRT’program is found to be effective,it will be an accessible,affordable and widely implementable intervention to help participants at moderate risk of substance use to reduce their *** potential benefit is to provide early intervention to high-risk patients in time and reduce the harmful consequences to individuals and society.

关键词： prevention SBIR random

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Radiofrequency field enhanced chemical ionization with vacuum ultraviolet lamp for miniature time-of-flight mass spectrometer

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Chinese Chemical Letters 2018年第5期29卷 707-710页

作者： Lijuan Zhou Jichun Jiang Kun Zhao Jinxu Li chenxin Wu Haiyang Li Di Tian Keyong Hou College of Instrumentation & Electrical Engineering Jilin University Changchun 130023 China Key Laboratory of Separation Science for Analytical Chemistry Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian 116023 China University of Chinese Academy of Sciences Beijing 100039 China

It is difficult to rapidly and on-line detect trace volatile organic compounds for miniature massspectrometry due to its limited sampling volume at slow pumping speed. In this paper, we developed anew radiofrequency field enhanced chemical ionization source （RF-ECI） with vacuum ultraviolet （VUV）lamp by coupling radiofrequency electric field and direct-current field together. The experiment resultsshowed that the sensitivity of benzene, toluene, hydrogen sulfide and other compounds increased by 2-3orders of magnitude under the introduction of RF-ECI comparing to traditional single photon ionization（SPI）. At the same time, the reagent ion of O2＋ realized the charge transfer reaction chemical ionization,and the RF-ECI effectively expanded the detection range of the VUV lamp based SPI. The VUV lamp hasinherent advantages in the on-site analytical instrument for its small size and low power consumption,and the VUV lamp based RF-ECI miniature time-of-flight mass spectrometer （TOFMS） has a limit-of-detection for H2S as low as 0.0571 mg/m3, and it is expected to be used widely in the field of on-site rapidanalvsis.

关键词： Radio-frequency field enhanced chemical ionization Vacuum ultraviolet lamp Single photon ionization Miniature time-of-flight mass spectrometer On site analysis

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The advancement of stem cell transplantation to treat acute myocardial infarction

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海南医学 2002年第11期13卷 112-114页

作者： YANGShuixiing chenxin Fu－WaiHospital Beijing100037

The current findings have provided compelling evidence that a specific opulation of cells derived from bone marrow,stem cells,might hold the key to producing functional cardiac cells in damaged hearts. This cellular therapeutics intervention reduced the infracted area and improved cardiac haemodynamics. Our rhesus monkey studies have also confirmed that stem cells transplantation therapy can improve the infarcted cardiac functions. Recent interest has focused on not only the development of stem cells as a therapeutic option in treatment of the disease,but also the mobilization of bone marrow cells repairing the infarcted heart,and try to get no immune-rejection cardiomyocyte *** objective of this review is to describe the derivation and unique properties of human ES *** emphasis well be given to summarizing recent studies that focus on the potential of human ES cells for differentiation into cardiomyocyte in vitro and in vivo,especially the advancement of stem cells transplantation for treating *** will also outline key scientific questions that will need to be answered before the full therapeutic potential of human ES cells can be used.

关键词：干细胞移植急性心肌梗塞危险性 AMI

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Interpreting serological studies on severe acute respiratory syndrome: defining the reference

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Chinese Medical Journal 2005年第6期118卷 443-445页

作者： chenxin-chun SUNYong-chang DepartmentofPediatrics UniversityofArizonaTucsonAZ85721.USA／／ShenzhenEastLakeHospitalShenzhen518020China DepartmentofRespiratory MedicinePekingUniversityThirdHospitalBeijing100083China

Severe acute respiratory syndrome (SARS) was first identified in November 2002 in China and spread internationally causing more than 910 deaths before being contained in 2003. A novel coronavirus, named SARS coronavir... 详细信息

关键词： SARS coronavirus

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Metal Halide Perovskite for next-generation optoelectronics:progresses and prospects

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eLight 2023年第1期3卷 252-267页

作者： He Dong chenxin Ran Weiyin Gao Mingjie Li Yingdong Xia Wei Huang Frontiers Science Center for Flexible Electronics Xi’an Institute of Flexible Electronics(IFE)and Xi’an Institute of Biomedical Materials&EngineeringNorthwestern Polytechnical UniversityXi’an 710072China Key Laboratory of Flexible Electronics(KLOFE)&Institution of Advanced Materials(IAM) Nanjing Tech University(NanjingTech)Nanjing 211816JiangsuChina Key Laboratory for Organic Electronics&Information Displays(KLOEID) and Institute of Advanced Materials(IAM)Nanjing University of Posts and TelecommunicationsNanjing 210023JiangsuChina Department of Applied Physics The Hong Kong Polytechnic UniversityKowloon 999077Hong KongChina Shenzhen Research Institute The Hong Kong Polytechnic UniversityShenzhen 518057GuangdongChina

Metal halide perovskites(MHPs),emerging as innovative and promising semiconductor materials with prominent optoelectronic properties,has been pioneering a new era of light management(ranging from emission,absorption,modulation,to transmission)for next-generation optoelectronic ***,the exploration of fundamental characteristics of MHPs and their devices is the main research theme during the past decade,while in the next decade,it will be primarily critical to promote their implantation in the next-generation *** this review,we first retrospect the historical research milestones of MHPs and their optoelectronic ***,we introduce the origin of the unique optoelectronic features of MHPs,based on which we highlight the tunability of these features via regulating the phase,dimensionality,composition,and geometry of ***,we show that owing to the convenient property control of MHPs,various optoelectronic devices with target performance can be *** last,we emphasize on the revolutionary applications of MHPs-based devices on the existing optoelectronic *** review demonstrates the key role of MHPs played in the development of modern optoelectronics,which is expected to inspire the novel research directions of MHPs and promote the widespread applications of MHPs in the next-generation optoelectronics.

关键词： Metal halide perovskites Optoelectronic characteristics Optoelectronic devices Revolutionary applications

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