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Incidence and mortality of female breast cancer in the AsiaPacific region

Cancer Biology & Medicine 2014年第2期11卷 101-115页

作者： Danny R.Youlden Susanna M.Cramb cheng har yip Peter D.Baade Cancer Council Queensland School of Mathematical Sciences Queensland University of Technology Faculty of Medicine University of Malaya Griffith Health Institute Griffith University School of Public Health and Social Work Queensland University of Technology

Objective: To provide an overview of the incidence and mortality of female breast cancer for countries in the Asia-Pacific ***: Statistical information about breast cancer was obtained from publicly available cancer registry and mortality databases(such as GLOBOCAN), and supplemented with data requested from individual cancer registries. Rates were directly age-standardised to the Segi World Standard population and trends were analysed using joinpoint ***: Breast cancer was the most common type of cancer among females in the region, accounting for 18% of all cases in 2012, and was the fourth most common cause of cancer-related deaths(9%). Although incidence rates remain much higher in New Zealand and Australia, rapid rises in recent years were observed in several Asian countries. Large increases in breast cancer mortality rates also occurred in many areas, particularly Malaysia and Thailand, in contrast to stabilising trends in Hong Kong and Singapore, while decreases have been recorded in Australia and New Zealand. Mortality trends tended to be more favourable for women aged under 50 compared to those who were 50 years or older. Conclusion: It is anticipated that incidence rates of breast cancer in developing countries throughout the Asia-Pacific region will continue to increase. Early detection and access to optimal treatment are the keys to reducing breast cancerrelated mortality, but cultural and economic obstacles persist. Consequently, the challenge is to customise breast cancer control initiatives to the particular needs of each country to ensure the best possible outcomes.

关键词： Asia-Pacific region female breast cancer epidemiology incidence mortality

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乳腺癌的全球化趋势

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抗癌之窗 2015年第5期 9-12页

作者： cheng-har yip 吉隆坡东姑阿都拉曼医学院

在全球范围内，无论是发达国家还是发展中国家，乳腺癌是女性最常见的癌症。2012年，估计全球约有167万病例（2012GLOBOCAN）。从欧洲国家的96／10万到非洲的27／10万，不同地区发病率不同。2012年，乳腺癌是欠发达地区的主要死亡原因... 详细信息

在全球范围内，无论是发达国家还是发展中国家，乳腺癌是女性最常见的癌症。2012年，估计全球约有167万病例（2012GLOBOCAN）。从欧洲国家的96／10万到非洲的27／10万，不同地区发病率不同。2012年，乳腺癌是欠发达地区的主要死亡原因（32．4万例），是发达地区的第二大死因（19．8万例）。尽管发病率在发达国家已经稳定，而在发展中国家仍在不断上升。

关键词：乳腺癌全球化发展中国家地区发病率欠发达地区主要死亡原因发达国家欧洲国家

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Chinese herbal medicine decreases incidence of hepatocellular carcinoma in diabetes mellitus patients with regular insulin management

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 716-731页

作者： Hsiang-Chun Lai Ju-Chien cheng Hei-Tung yip Long-Bin Jeng Sheng-Teng Huang Graduate Institute of Chinese Medicine School of Chinese MedicineCollege of Chinese MedicineChina Medical UniversityTaichung 404328TaiwanChina Department of Medical Laboratory Science and Biotechnology China Medical UniversityTaichung 404TaiwanChina Management Office for Health Data China Medical University HospitalTaichung 404327TaiwanChina Organ Transplantation Center China Medical University HospitalTaichung 40447TaiwanChina Department of Chinese Medicine China Medical University HospitalSchool of Chinese MedicineChina Medical UniversityTaichung 40447TaiwanChina

BACKGROUND Type 2 diabetes mellitus(DM)is an independent risk factor for hepatocellular carcinoma(HCC),while insulin is a potent *** a new therapeutic modality for preventing insulin users from developing HCC is a critical goal for *** To investigate whether regular herbal medicine use can decrease HCC risk in DM patients with regular insulin *** We used data acquired from the Taiwan,Chinaese National Health Insurance research database between 2000 and *** identified patients with DM who were prescribed insulin for>3 *** herb user group was further defined as patients prescribed herbal medication for DM for>3 months per annum during RESULTS We initially enrolled 657144 DM patients with regular insulin use from 2000 to *** these,46849 patients had used a herbal treatment for DM,and 140547 patients were included as the matched control *** baseline variables were similar between the herb users and *** patients with regular herb use had a 12%decreased risk of HCC compared with the control group[adjusted hazard ratio(aHR)=0.88,95%CI=0.80–0.97].The cumulative incidence of HCC in the herb users was significantly lower than that of the *** with a herb use of>5 years cumulatively exhibited a protective effect against development of HCC(aHR=0.82,Pharmacological effects of the *** analysis indicated that Astragalus propinquus(Huang Qi)plus Salvia miltiorrhiza Bunge(Dan Shen),and Astragalus propinquus(Huang Qi)plus Trichosanthes kirilowii Maxim.(Tian Hua Fen)were the most frequent combination of single ***,Ji Sheng Shen Qi Wan plus Dan Shen was the most frequent combination of herbs and *** This large-scale retrospective cohort study reveals th

关键词： Hepatocellular carcinoma Diabetes mellitus Insulin Herb Taiwan,Chinaese National health insurance research database

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鞘层电容对快速扫描双探针伏安曲线的影响

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核聚变与等离子体物理 2024年第2期44卷 198-205页

作者：孙海岗靳琛垚张炜江堤叶孜崇中国科学院合肥物质科学研究院等离子体物理研究所合肥230031 中国科学技术大学科学岛分院合肥230026

建造了基于多偶极腔体热阴极放电形式搭建的500kHz不对称快速扫描双探针系统,以电容对测量结果的影响进行实验研究。对不同扫描频率下不同尺寸的快速扫描不对称朗缪尔双探针受离子饱和电流及鞘电流影响的结果进行了对比分析。这项研究... 详细信息

建造了基于多偶极腔体热阴极放电形式搭建的500kHz不对称快速扫描双探针系统,以电容对测量结果的影响进行实验研究。对不同扫描频率下不同尺寸的快速扫描不对称朗缪尔双探针受离子饱和电流及鞘电流影响的结果进行了对比分析。这项研究对于不同扫描频率下快速扫描不对称双探针的选择应用有着参考和指导意义。

关键词：朗缪尔探针等离子体诊断鞘层电容

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The interplay between the muscle and liver in the regulation of glucolipid metabolism

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Journal of Molecular Cell Biology 2023年第12期15卷 28-33页

作者： cheng Chen Liping Xie Mingliang Zhang Shama Kenneth King yip cheng Weiping Jia Shanghai Diabetes Institute Department of Endocrinology and MetabolismShanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200032China Department of Health Technology and Informatics The Hong Kong Polytechnic UniversityHung HomHong Kong SARChina

The liver,adipose tissue,and skeletal muscle work not only independently but also collaboratively to maintain glucose and lipid homeostasis under different nutritional and environmental conditions(da Silva Rosa et al.,2020).Dysfunctions of these active metabolic and endocrine tissues lead to a variety of metabolic,cardiovascular,and cerebrovascular disorders,including type 2 diabetes mellitus(T2DM),atherosclerosis,metabolic-associated fatty liver disease(MAFLD;also previously known as non-alcoholic fatty liver disease),and stroke(Wang et al.,2020).Here,we summarize the interaction between the liver and muscle in the regulation of glucolipid metabolism and discuss the key metabolic factors that mediate their crosstalk in the context of physiological(fasting and postprandial state)and pathological conditions(obesity,T2DM,and MAFLD).

关键词： metabolism T2DM

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Prognostic factors of survival and a new scoring system for liver resection of colorectal liver metastasis

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World Journal of Hepatology 2022年第1期14卷 209-223页

作者： Kai-Chi cheng Ada Sze-Man yip Department of Surgery Kwong Wah HospitalHong KongChina

BACKGROUND Hepatic resection has become the preferred treatment of choice for colorectal liver metastasis(CLM)*** To identify the prognostic factors and to formulate a new scoring system for management of *** Clinicopathologic and long-term survival data were analyzed to identify the significant predictors of survival by univariate and multivariate analyses with the Cox model.A clinical score was constructed based on the analysis *** Three factors of worse overall survival were identified in the multivariate *** were number of liver metastases≥5,size of the largest liver lesion≥4 cm,and the presence of nodal metastasis from the primary *** three factors were chosen as criteria for a clinical risk score for overall *** clinical score highly correlated with median overall survival and 5-year survival(P=0.002).CONCLUSION Priority over surgical resection should be given to the lowest score groups,and alternative oncological treatment should be considered in patients with the highest score.

关键词： Colorectal cancer Liver metastasis Liver resection Long-term outcome Overall survival Disease-free survival Prognosis Score

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Economic analysis in product design——A case study of a TCM dietary supplement

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Chinese Journal of Chemical Engineering 2016年第1期24卷 202-214页

作者： Yuen Shan cheng Ka yip Fung Ka Ming Ng Christianto Wibowo Department of Chemical and Biomolecular Engineering The Hong Kong University of Science and Technology ClearWaterBay Technology Inc.

An approach for the economic analysis of chemical product design is proposed. It takes into account of customers' preference on product quality and economic considerations such as pricing, profit, market share, capital investment, and operating cost. The activities needed to support business decision making – identifying product quality, estimating product cost, calculating financial metrics, and performing make–buy analysis – are *** design of a Ganoderma lucidum dietary supplement, a traditional Chinese medicinal(TCM) product, is used to illustrate all the activities in this approach.

关键词： Product design Product conceptualization TCM dietary supplement Economic analysis Make–buy analysis

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Understanding the role of interconnecting layer on determining monolithic perovskite/organic tandem device carrier recombination properties

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Journal of Energy Chemistry 2022年第8期31卷 12-19,I0001页

作者： Yue-Min Xie Tianqi Niu Qin Yao Qifan Xue Zixin Zeng Yuanhang cheng Hin-Lap yip Yong Cao Institute of Polymer Optoelectronic Materials and Devices State Key Laboratory of Luminescent Materials and DevicesSouth China University of TechnologyGuangzhou 510640GuangdongChina Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates(South China University of Technology) Guangzhou 510640GuangdongChina Department of Materials Science and Engineering City University of Hong KongKowloon 999077Hong KongChina School of Energy and Environmental Science City University of Hong KongKowloon 999077Hong KongChina

As one of the core parts of two-terminal(2 T) monolithic tandem photovoltaics, the interconnecting layers(ICLs) play a critical role in modulating the carrier transport and recombination between the sub-cells,and thus influencing the tandem device performance. Here, for the first time, the relationship between ICLs architecture and 2 T monolithic perovskite/organic tandem device performance has been studied by investigating the change of ICLs composition layer thickness on the ICLs optical and electrical properties, sub-cells EQE properties, and tandem device J-V properties. It is revealed that the ability of ICLs on modulating the sub-cells carrier balance properties is strongly associated with its composited layers thickness, and the tandem device carrier balance properties can be reflected by the relative EQE intensity between the sub-cells. Finally, with a deep understanding of the mechanisms, rational design of ICLs can be made to benefit the tandem device development. Based on the optimized ICL a high PCE of 20.03% is achieved.

关键词： Monolithic perovskite/organic tandem solar cells Interconnecting layers(ICLs) Carrier modulating Carrier balance properties

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LINEAR AND HYPERBRANCHED POLYMERS WITH HIGH THERMAL STABILITY AND LUMINESCENCE EFFICIENCY

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Chinese Journal of Polymer Science 2001年第6期19卷 585-590页

作者： Jacky Wing yip Lam Jing-dong Luo Han Peng Zhi-liang Xie Kai-tian Xue Yu-ping Dong Lin cheng cheng-feng Qiu Hoi Sing Kwok Ben-zhong Tang Departments of Chemistry and Electrical & Electronic Engineering Hong Kong University of Science & Technology Clear Water Bay, Kowloon, Hong Kong China 香港科技大学香港

New acetylene monomers, 6-{[(1-naphthylethynyl-4-phenyl)carbonyl]oxy}-1-phenyl-1-hexyne (1), 2,5-diethynyl-thiophene (3), and 4,4'-diethynylbiphenyl (6) were synthesized. Homopolymerization of 1 and copolycyclotrimerizations of 3 and 6 with 1-heptyne and 1-octyne have been achieved with WCl6- and TaCl5-Ph4Sn catalysts, respectively, giving soluble linear disubstituted polyacetylene (2) and hyperbranched polyarylenes (5 and 8) with high molecular weights (up to 1.2 x 10(5)) in high yields (up to 98%). The structures and properties of the polymers are characterized and evaluated by R NMR, TGA, UV, photoluminescence (PL), and electroluminescence (EL) analyses. All the polymers possess high thermal stability and emit strong blue light upon photoexcitation. The intensity of the emitted light is greater than that of poly(1-phenyl-1-octyne), a well-known highly luminescent disubstituted polyacetylene. Little aggregation-induced red shift in the PL was observed in the thin films of the polymers. By constructing a multi-layer EL device, high EL quantum yield (0.18%) has been achieved in 2, which are the best results for substituted polyacetylenes attainable so far.

关键词： disubstituted polyacetylene hyperbranched polyarylene light emission

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光伏多功能并网逆变器不同出力状态下无功和谐波优化方法

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电力自动化设备 2024年第1期44卷 80-87页

作者：王果武旭李龙张梦圆李旭哲成柯张建雄兰州交通大学自动化与电气工程学院甘肃兰州730070 青岛鼎信通讯股份有限公司山东青岛266000 武汉大学电气与自动化学院湖北武汉430072

利用光伏多功能并网逆变器所具有的电能质量治理、谐波谐振抑制的主动优势,结合逆变器在不同出力状态下光伏发电系统的输出特性,构建光伏多功能并网逆变器不同出力状态下的无功和谐波优化方法。在所提3层优化策略中,上层优化策略以光伏... 详细信息

利用光伏多功能并网逆变器所具有的电能质量治理、谐波谐振抑制的主动优势,结合逆变器在不同出力状态下光伏发电系统的输出特性,构建光伏多功能并网逆变器不同出力状态下的无功和谐波优化方法。在所提3层优化策略中,上层优化策略以光伏并网有功功率最大化为目标函数,中层优化策略以电压谐波总畸变率和电压偏差达到相应电能质量规定指标为目标函数,下层优化策略以电压谐波总畸变率和电压偏差最小为目标函数,并采用自适应蚁群算法进行求解。基于IEEE 33节点系统进行算例分析,结果表明:基于逆变器不同出力状态的优化方法可以有效改善电网的电能质量,较好地提升电网运行的经济性;在系统稳定运行的基础上,光伏多功能并网逆变器在不同出力状态下分阶段、分主次地治理谐波和调整电压偏差,治理效果更佳。

关键词：光伏发电系统多功能并网逆变器优化策略无功优化谐波治理

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