Prognostic factors of survival and a new scoring system for liver resection of colorectal liver metastasis
作者机构：Department of SurgeryKwong Wah HospitalHong KongChina
出 版 物：《World Journal of Hepatology》 (世界肝病学杂志（英文版）（电子版）)
年 卷 期：2022年第14卷第1期
页 面：209-223页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Colorectal cancer Liver metastasis Liver resection Long-term outcome Overall survival Disease-free survival Prognosis Score
摘 要：BACKGROUND Hepatic resection has become the preferred treatment of choice for colorectal liver metastasis(CLM)*** To identify the prognostic factors and to formulate a new scoring system for management of *** Clinicopathologic and long-term survival data were analyzed to identify the significant predictors of survival by univariate and multivariate analyses with the Cox model.A clinical score was constructed based on the analysis *** Three factors of worse overall survival were identified in the multivariate *** were number of liver metastases≥5,size of the largest liver lesion≥4 cm,and the presence of nodal metastasis from the primary *** three factors were chosen as criteria for a clinical risk score for overall *** clinical score highly correlated with median overall survival and 5-year survival(P=0.002).CONCLUSION Priority over surgical resection should be given to the lowest score groups,and alternative oncological treatment should be considered in patients with the highest score.
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