检索结果-南通市图书馆

Photonics Research 2024年第1期12卷 40-50页

作者： YUAN SHEN XIAOQIAN SHU LINGMEI MA shaoliang YU GENGXIN chen LIU LIU RENYOU GE BIGENG chen YUNJIANG RAO Research Center for Optical Fiber Sensing Zhejiang LaboratoryHangzhou 311100China Research Center for Intelligent Optoelectronic Computing Zhejiang LaboratoryHangzhou 311100China International Research Center for Advanced Photonics College of Optical Science and EngineeringZhejiang UniversityHangzhou 310058China Fiber Optics Research Center(FORC) Key Laboratory of Optical Fiber Sensing and CommunicationsUniversity of Electronic Science and Technology of ChinaChengdu 611731China

We experimentally demonstrate ultra-high extinction ratio(ER)optical pulse modulation with an electro-optical modulator(EOM)on thin film lithium niobate(TFLN)and its application for fiber optic distributed acoustic sensing(DAS).An interface carrier effect leading to a relaxation-tail response of TFLN EOM is discovered,which can be well addressed by a small compensation component following the main driving *** ultrahigh ER>50 dB is achieved by canceling out the tailed response during pulse modulation using the EOM based on a cascaded Mach–Zehnder interferometer(MZI)*** modulated optical_(√)pulses are then utilized as a probe light for a DAS system,showing a sensitivity up to-62.9 dB·rad∕Hz~2(7 pε/Hz)for 2-km single-mode sensing *** crosstalk suppression of 24.9 dB along the fiber is also obtained when the ER is improved from 20 dB to 50 dB,clearly revealing its importance to the sensing performance.

关键词： modulator pulse interferometer

A New Coronavirus Estimation Global Score for Predicting Mortality During Hospitalization in Patients with COVID-19

在线全文

学校读者我要写书评

暂无评论

Cardiology Discovery 2022年第2期2卷 69-76页

作者： Hesong Zeng Xingwei He Wanjun Liu Jing Kan Liqun He Jinhe Zhao Cynthia chen Junjie Zhang shaoliang chen Division of Cardiology Tongji HospitalTongji Medical CollegeHuazhong University of Science&TechnologyWuhanHubei 430030China Division of Cardiology Nanjing First HospitalNanjing Medical UniversityNanjingJiangsu 210006China Division of Cardiology Wuhan First HospitalWuhanHubei 430022China Division of Cardiology Tianyou Hospital affiliated to Wuhan University of Science&TechnologyWuhanHubei 430064China Mailman School of Public Health Columbia UniversityNew YorkNew York 10027USA College of Pharmacy Nanjing Medical UniversityNanjingJiangsu 210002China.

Objective:Coronavirus disease 2019(COVID-19)exists as a *** during hospitalization is multifactorial,and there is urgent need for a risk stratification model to predict in-hospital death among COVID-19 *** we aimed to construct a risk score system for early identification of COVID-19 patients at high probability of dying during in-hospital ***:In this retrospective analysis,a total of 821 confirmed COVID-19 patients from 3 centers were assigned to developmental(n=411,between January 14,2020 and February 11,2020)and validation(n=410,between February 14,2020 and March 13,2020)*** on demographic,symptomatic,and laboratory variables,a new Coronavirus estimation global(CORE-G)score for prediction of in-hospital death was established from the developmental group,and its performance was then evaluated in the validation ***:The CORE-G score consisted of 18 variables(5 demographics,2 symptoms,and 11 laboratory measurements)with a sum of 69.5 ***-of-fit tests indicated that the model performed well in the developmental group(H=3.210,P=0.880),and it was well validated in the validation group(H=6.948,P=0.542).The areas under the receiver operating characteristic curves were 0.955 in the developmental group(sensitivity,94.1%;specificity,83.4%)and 0.937 in the validation group(sensitivity,87.2%;specificity,84.2%).The mortality rate was not significantly different between the developmental(n=85,20.7%)and validation(n=94,22.9%,P=0.608)***:The CORE-G score provides an estimate of the risk of in-hospital *** is the first step toward the clinical use of the CORE-G score for predicting outcome in COVID-19 patients.

关键词： Hospital mortality Coronavirus estimation global score COVID-19 Goodness-of-fit Receiver operating characteristics Risk stratification

Impact of Coronary Chronic Total Occlusion on Long-term Clinical Outcome in Patients with Unprotected Left Main Disease Undergoing Percutaneous Coronary Intervention

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cardiology Discovery 2022年第3期2卷 145-151页

作者： Imad Sheiban Filippo Figini Valeria Gaspartto Claudio Moretti Filippo Leonardo shaoliang chen Fabrizio D’Ascenzo Interventional Cardiology P.Pederzoli HospitalPeschiera del GardaVerona 37019Italy Division of Cardiology Chivasso HospitalChivassoTorino 10034Italy Cardiology and Catheter Laboratory Nanjing First HospitalNanjing Medical UniversityNanjingJiangsu 210006China Division of Cardiology University of TurinTurin 8-10124Italy.

Objectives:Reported data regarding the prevalence,prognostic impact,and safety and efficacy of revascularization of coronary chronic total occlusion(CTO)in patients with left main coronary artery(LMCA)disease who undergo percutaneous coronary intervention(PCI)are *** aim of the present study was to compare clinical outcomes among patients with LMCA disease undergoing *** were compared between those with and without coronary CTO and between those with CTO who had successful and unsuccessful CTO recanalization ***:All consecutive patients with significant LMCA disease(>50%stenosis at coronary angiography)who underwent PCI between July 2014 and December 2018 were retrospectively included in our *** primary endpoint of the study was long-term *** endpoints included the incidence of myocardial infarction,repeat percutaneous or surgical revascularization,stroke,and stent ***:Between July 2014 and December 2018,578 patients underwent PCI for LMCA disease at Pederzoli Hospital and University of Turin were *** were divided into 3 groups:group A:374(65%)patients without CTO,group B:108(19%)patients with untreated or unsuccessfully treated CTO,and group C:96(17%)patients with successfully treated *** a median follow-up of(1090±279)days,there were no statistically significant differences between the groups in terms of the primary and secondary ***,there was a trend towards higher mortality in patients with untreated or unsuccessfully treated CTO(13%vs.19%vs.14%in groups A,B,and C,respectively;P=0.12).The primary and secondary endpoints were further analyzed based on the presence or absence of myocardial viability:subgroup C1:54(56%)patients with successful percutaneous transluminal coronary angioplasty(PTCA)having viability,and subgroup C2:42(44%)patients with successful PTCA not having *** was a trend toward a statistically significant higher rate of death among patients

关键词： Percutaneous coronary interventions Left main coronary artery disease Coronary chronic total occlusion Myocardial viability

经皮肺动脉去神经术治疗肺动脉高压的中国专家建议

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中华心血管病杂志 2024年第6期52卷 647-658页

作者：中华医学会心血管病学分会王琦光李江杨振文沈节艳张刚成张航张曹进陈绍良范粉灵郭小梅韩雅玲辜和平翟振国不详解放军北部战区总医院中南大学湘雅二医院天津医科大学总医院上海交通大学医学院附属仁济医院武汉大学中南医院南京医科大学附属南京医院南京市第一医院广东省人民医院南京医科大学附属南京医院(南京市第一医院)心内科南京210012 西安交通大学第一附属医院华中科技大学同济医学院附属同济医院郑州大学第一附属医院中日友好医院解放军北部战区总医院心血管内科沈阳110016

肺动脉高压在病理机制、诊断、风险评估及治疗等方面有很多新进展。交感神经学说在肺动脉高压发生及发展中起着重要作用。经皮肺动脉去神经术通过对肺动脉主干及左肺动脉口3个黄金消融靶点进行局部交感神经消融,以达到治疗肺动脉高压的... 详细信息

肺动脉高压在病理机制、诊断、风险评估及治疗等方面有很多新进展。交感神经学说在肺动脉高压发生及发展中起着重要作用。经皮肺动脉去神经术通过对肺动脉主干及左肺动脉口3个黄金消融靶点进行局部交感神经消融,以达到治疗肺动脉高压的目的。中华医学会心血管病学分会心血管临床研究学组和肺血管病学组围绕经皮肺动脉去神经术的实验依据、循证医学证据、适应证及操作步骤制定了该建议,旨在规范经皮肺动脉去神经术治疗肺动脉高压的诊治。

关键词：经皮肺动脉去神经术肺动脉高压专家建议

在线全文

学校读者我要写书评

暂无评论

卵圆孔未闭规范化诊疗中国专家共识

中华心血管病杂志 2024年第4期52卷 369-383页

作者：中华医学会心血管病学分会中华心血管病杂志编辑委员会陈绍良陈茂韩雅玲张曹进张刚成王琦光胡海波陈晓彬不详南京医科大学附属南京医院(南京市第一医院)心血管内科南京210012 四川大学华西医院心脏内科成都610044 解放军北部战区总医院心血管内科沈阳110016 广东省人民医院武汉大学中南医院解放军北部战区总医院中国医学科学院阜外医院中南大学湘雅医院

卵圆孔未闭(PFO)与缺血性卒中、先兆偏头痛等疾病相关,循证医学证据提示PFO封堵术可降低卒中复发风险。国内外神经科、心脏科及相关专业的专家学者们对PFO相关疾病的防治日益重视,但临床实践中仍存在一些不足。为规范临床诊疗行为,中华... 详细信息

卵圆孔未闭(PFO)与缺血性卒中、先兆偏头痛等疾病相关,循证医学证据提示PFO封堵术可降低卒中复发风险。国内外神经科、心脏科及相关专业的专家学者们对PFO相关疾病的防治日益重视,但临床实践中仍存在一些不足。为规范临床诊疗行为,中华医学会心血管病学分会、中华心血管病杂志编辑委员会组织国内心血管病学专家、神经病学专家、影像诊断学专家撰写了该共识,明确PFO相关综合征的诊断标准、筛查和诊断流程、治疗目标和疗效评价体系。

关键词：卵圆孔未闭诊断治疗

Dosimetry of chimeric TNT in lung tumor patients

在线全文

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2007年第4期18卷 227-231页

作者： chen Yangchun chen shaoliang JU Dianwen SHI Hongcheng YAO Zhifeng Nuclear Medicine Department Zhongshan Hospital Fudan University Shanghai200032 China PET/CT Center of the First Affiliated Hospital of Guangzhou Medical College Guangzhou 510230 China Shanghai MediPharm Biotech Co Ltd Shanghai 201203 China

The purpose of this study was to assess the absorbed dose of tumor and main critical organs in 131I labeled chimeric tumor necrotic treatment (chTNT). In 9 patients, a single intravenous dose of (29.6±3.7) MBq/kg was administered. Blood samples were drawn at different time intervals, and urine was collected for up to one week. Tissue distribution of 131I-chTNT was followed for up to one week by gamma camera imaging. Absorbed doses to the whole body and to normal organs were computed according to the MIRD scheme using Mirdose-3 software. S-factors for lung tumors were estimated by comparison with lungs of similar mass and position in the body. It was found that mean serum disappearance half time values for 131I-chTNT were (4.93±9.36) h and (61.7±21.2) h for α, β respectively, while that for whole body was(99±10) h. Mean urine biological clearance half time value was (90±10) h. The absorbed dose to tumor was (8.28±2.65) Gy, and the tumor-to-nontumor dose ratio was 3.95±1.55. And the mean effective dose to patients was (1.02±0.29) mSv/MBq.

关键词：肺癌放射疗法放射量碘放射性同位素

Chinese Guideline for Percutaneous Coronary Intervention in Patients with Left Main Bifurcation Disease

在线全文

学校读者我要写书评

暂无评论

Cardiology Discovery 2022年第3期2卷 134-144页

作者： Chinese Society of Cardiology,Chinese Medical Association Editorial Board of Chinese Journal of Cardiology shaoliang chen Yaling Han 不详 Nanjing First Hospital General Hospital of Northern Theater Command

The coronary left main(LM)artery is characterized by large caliber,length varying from15 mm,and 2 large daughter vessels branching from it;it supplies blood to a large area(>75%)of the *** bifurcation lesion is defined as the presence of atherosclerosis involving either or both of the 2 daughter ***,the optimal strategy of revascularization for diseased LM has been an interesting research topic for a long *** developments in percutaneous techniques,design,and materials of drug-eluting stents;intravascular imaging;new generation of antiplatelet medications;and particularly recent pooled evidence from randomized clinical trials comparing percutaneous coronary intervention with coronary artery bypass grafting,implantation of a drug-eluting stenting with or without other approved techniques is considered an important therapeutic approach for LM bifurcation *** the anatomical complexity of the LM,stenting LM bifurcations is technically demanding,and intraprocedural complications can be catastrophic given the large amount of jeopardized ***,the Chinese Society of Cardiology designed a writing committee with members from 3 working groups(ie,clinical research,intravascular imaging and physiology,and interventional cardiology)for the first time,to write a guideline on percutaneous treatment for LM bifurcation lesions,with view to improve the procedural quality and clinical *** guideline consists of introduction,anatomical description of the LM tree,risk stratification,strategies of revascularization,antiplatelet strategy,follow-up,and long-term management for patients with LM bifurcation lesions.

关键词： Coronary artery disease Left main bifurcation lesions Percutaneous coronary intervention Guideline

非ST段抬高型急性冠脉综合征诊断和治疗指南(2024)

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中华心血管病杂志 2024年第6期52卷 615-646页

作者：中华医学会心血管病学分会中华心血管病杂志编辑委员会李毅刘巍袁晋青张波韩雅玲杨跃进陈绍良袁祖贻不详解放军北部战区总医院北京积水潭医院中国医学科学院阜外医院大连医科大学附属第一医院解放军北部战区总医院心血管内科沈阳110016 中国医学科学院阜外医院冠心病中心北京100037 南京医科大学附属南京医院/南京市第一医院心血管内科南京210006 西安交通大学第一附属医院心血管内科西安710061

近年来,在非ST段抬高型急性冠脉综合征(NSTE-ACS)诊断和治疗领域积累了大量的新证据。为进一步优化我国NSTE-ACS的诊治实践,由中华医学会心血管病学分会和中华心血管病杂志编辑委员会组织专家组,以临床问题为导向,在2016版NSTE-ACS指南... 详细信息

近年来,在非ST段抬高型急性冠脉综合征(NSTE-ACS)诊断和治疗领域积累了大量的新证据。为进一步优化我国NSTE-ACS的诊治实践,由中华医学会心血管病学分会和中华心血管病杂志编辑委员会组织专家组,以临床问题为导向,在2016版NSTE-ACS指南基础上,参考最新循证医学证据和国际指南,结合我国国情及临床实践经验,制定了此版指南,以推进我国NSTE-ACS的规范化管理。

关键词：急性冠状动脉综合征诊断治疗二级预防

Comparison of two and three dimensional quantitative coronaryangiography to intravascular ultrasound in the assessment of leftmain coronary artery bifurcation lesions

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2014年第6期127卷 1012-1021页

作者： Kan Jing Gao Xiaofei Kumar Gami Sandeep Xu Haimei Zhao Yingying chen shaoliang chen Feng Department of Cardiology Nanjing First Hospital Nanjing Medical University Nanjing Jiangsu 210006 China School of Public Health Nanjing Medical University NanjingJiangsu 210006 China

Background Angiographic evaluation of left main coronary artery(LMCA) bifurcation lesions is often limited. two dimensional(2D) quantitative coronary angiography(QCA) with segmental analysis provides accuracy for quantification of the degree of stenosis in the main vessel and side branch ostium but can be affected by foreshortening and variable magnification. The accuracy of three dimensional(3D) QCA has recently developed to overcome 2D QCA limitations, however, accuracy and precision of 3D bifurcation QCA measurements in LMCA bifurcation lesions has not been *** We investigated whether such 3D and 2D bifurcation QCA measurements differ in their accuracy in assessing significant LMCA bifurcation lesions defined by intravascular ultrasound(IVUS) as a minimum luminal area(MLA) <6 mm2 of LMCA and MLA <4 mm2 of proximal left anterior descending(LAD) and/or proximal left circumflex(LCX)Results LMCA bifurcation lesions were assessed in 44 patients undergoing elective percutaneous coronary intervention. From 2D QCA measurements, MLA correlated moderately with threshold intravascular ultrasound MLA for LMCA(r=0.81, P <0.000 1), LAD(r=0.54, P=0.000 1) and LCX(r=0.58, P <0.000 1). Severity of lesion as MLA by derived 3D QCA, correlated moderately with threshold intravascular ultrasound MLA for LMCA(r=0.84, P <0.000 1), LAD(r=0.53, P=0.000 2); LCX(r=0.66, P <0.000 1). Overall, the C statistics tended to be slightly higher for 3D QCA and 2D QCA measurements in LMCA segment compared with proximal LAD and LCX segments, and there were no significant predictive power of percent diameter stenosis and percent area stenosis on 3D QCA for LCX IVUS MLA <4 mm2(percent diameter stenosis: area under curve 0.55, cutoff 23%, sensitivity 88%, specificity 37%, P=0.618 6; percent arer stenosis: area under curve 0.56, cutoff 41%, sensitivity 83%, specificity 38%, P=0.518 4, respectively).Conclusions The accuracy of 3D bifurcation QCA in detecting significant LMCA bifurcation les

关键词： three dimensional quantitative coronary angiography intravascular ultrasound left main coronary artery

Safety and efficacy of a novel abluminal groove-filled biodegradablepolymer sirolimus-eluting stent for the treatment of de novo coronarylesions： 12-month results from the TARGET II trial

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2014年第6期127卷 1027-1032页

作者： Xu Bo Zhao Yelin Yang Yuejin Zhang Ruiyan Li Hui Ma Changsheng chen shaoliang Department of Cardiology Fu Wai Hospital National Center for Cardiovascular Diseases Beijing 100037 China Department of Cardiology Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200025 China Department of Cardiology Daqing Oil Field General HospitalDaqing Heilongjiang 163114 China Department of Cardiology Affiliated Anzhen Hospital of Capital Medical University Beijing 100029 China Department of Cardiology Nanjing First Hospital Nanjing Medical University Nanjing Jiangsu 210006 China

Background In the TARGET I randomized controlled trial, the novel abluminal groove-filled biodegradable polymersirolimus-eluting stent FIREHAWK proved non-inferior to the everolimus-eluting stent in nine-month in-stent late loss insingle de novo coronary lesions. This study was aimed at evaluating clinical safety and effectiveness of FIREHAWK in amoderately complex population （including patients with small vessels, long lesions and multi-vessels）, and at validatingthe ability of the SYNTAX score （SS） to predict clinical outcomes in patients treated with this latest generation drug-elutingstent.

关键词： 5-YEAR FOLLOW-UP ARTERY-DISEASE CLINICAL-EVALUATION RANDOMIZED-TRIALS VESSEL SIZE INTERVENTION EVEROLIMUS OUTCOMES COHORT REVASCULARIZATION