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Unveiling hidden outcomes in malignant gastric outlet obstruction research–insights from a"Pancreas 2000"review

World Journal of Gastrointestinal Endoscopy 2024年第8期16卷 451-461页

作者： Filipe Vilas-Boas Giacomo Emanuele Maria Rizzo charles De Ponthaud stuart Robinson sebastien Gaujoux Gabriele Capurso Giuseppe Vanella Bahadır Bozkırlı Department of Gastroenterology São João University HospitalPorto 4200Portugal Endoscopy service Department of Diagnostic and Therapeutic ServicesScientific Institute for ResearchHospitalization and Healthcare-The Mediterranean Institute for Transplantation and Highly Specialized TherapiesPalermo 90127SiciliaItaly Department of Digestive Hepato-Biliary and Pancreatic Surgery and Liver TransplantationAP-HP Pitié-SalpêtriereSorbonne UniversitéParis 75013Île-de-FranceFrance Department of Hepatobiliary Pancreatic and Transplant SurgeryFreeman HospitalNewcastle NE77DNNewcastle upon TyneUnited Kingdom Division of Pancreato-Biliary Endoscopy and Endosonography Pancreas Translational and Clinical Research CenterIRCCS San Raffaele Scientific InstituteVita-Salute San Raffaele UniversityMilano 20132Italy Department of General surgery HPB-UnitAcıbadem Maslak HospitalIstanbul 34398Türkiye

Malignant gastric outlet obstruction(mGOO)is a major condition affecting patients with periampullary tumors,including pancreatic *** current treatment options include surgical gastroenterostomy,endoscopic stenting and more recently EUs-guided *** studies comparing the outcomes of the three procedures focus on technical success,clinical success and ***“occult”outcomes relevant to the patient’s viewpoints and perspective may ultimately impact on cancer-related and overall survival,such as body mass composition,nutritional biomarkers,chemotherapy tolerance and patient-reported quality of *** aim of this review is to provide an overview of potential key outcomes that should be explored in future comparative research around mGOO treatment options.

关键词： Malignant gastric outlet obstruction Endoscopic ultrasound-guided gastroenterostomy Patient-reported outcomes Body composition Nutrition Quality of life

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Operational guidance for aeration and flow augmentation for the Chicago Area Waterway system—A case study

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Water science and Engineering 2023年第4期16卷 345-358页

作者： charles s.Melching Jennifer Wasik Ed staudacher Thomas Minarik Melching Water solutions LLC GreenfieldWI 53221USA Metropolitan Water Reclamation District of Greater Chicago ChicagoIL 60611USA Metropolitan Water Reclamation District of Greater Chicago CiceroIL 60804USA

The Chicago Area Waterway system(CAWs)is a 133.9 km branching network of navigable waterways controlled by hydraulic structures,in which the majority of the flow is treated wastewater effluent and there are periods of substantial combined sewer *** CAWs comprises a network of effluent dominated *** stringent dissolved oxygen(DO)standards and a reduced flow augmentation allowance have been recently applied to the ***,a carefully calibrated and verified one-dimensional flow and water quality model was applied to the CAWs to determine emission-based real-time control guidelines for the operation of flow augmentation and aeration *** goal of these guidelines was to attain DO standards at least 95%of the ***“optimal”guidelines were tested for representative normal,dry,and wet *** finally proposed guidelines were found in the simulations to attain the 95%target for nearly all locations in the CAWs for the three test *** developed operational guidelines have been applied since 2018 and have shown improved attainment of the DO standards throughout the CAWs while at the same time achieving similar energy use at the aeration stations on the Calumet River system,greatly lowered energy use on the Chicago River system,and greatly lowered discretionary diversion from Lake Michigan,meeting the recently enacted lower amount of allowed annual discretionary *** case study indicates that emission-based real-time control developed from a well calibrated model holds potential to help many receiving water bodies achieve high attainment of water quality standards.

关键词： Water quality modeling Water quality management Real-time control stream aeration Flow augmentation Dissolved oxygen

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Further studies of the Cap Pushing Response in Honey Bees (Apis mellifera)

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Natural science 2024年第5期16卷 45-64页

作者： Riley J. Wincheski Kiri Li N. stauch Laura M. Grossner Maya B. Zepeda James W. Grice charles I. Abramson Department of Psychology Oklahoma State University Stillwater USA Laboratory of Comparative Psychology and Behavioral Biology Oklahoma State University Stillwater USA Department of Earth and Environmental sciences California State University Fresno USA

The Cap Pushing Response (CPR) is a free-flying technique used to study learning and memory in honey bees (Apis mellifera). The series of experiments outlined in this paper aimed to test whether honey bees exhibit the cognitive concept of “expectancy” utilizing the CPR in a weight differentiation paradigm. Five previous experiments in our laboratory have explored whether the concept of expectancy can account for honey bee performance and have all failed to support the cognitive interpretation. The first experiment examined if bees could differentiate between the two caps in the amount of force they used to push the cap and the distance the cap was pushed when the caps were presented one at a time. The second experiment explored cap weight preference by presenting bees with a choice between the two caps. The third and fourth experiments tested the bee’s ability to expect reward or punishment based on cap weight. Results revealed that bees were found to have a strong preference for the light cap and therefore were not able to expect reward or punishment based on cap weight. These experiments contribute to the debate on whether bees have “cognitive” representations and continue to support the behaviorist interpretation.

关键词： Apis mellifera Cap Pushing Response Cognition Learning

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sediment storage and morphology of the Yalu Tsangpo valley due to uneven uplift of the Himalaya

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science China Earth sciences 2015年第8期58卷 1440-1445页

作者： WANG ZhaoYin YU Guo An WANG XuZhao charles s. MELCHING LIU Le state Key Laboratory of Hydro-science and Engineering Tsinghua University Key Laboratory of Water Cycle and Related Land surface Processes Institute of Geographic Sciences and Natural Resources ResearchChinese Academy of Sciences Beijing Institute of Geology for Mineral Resources Environmental Consultant

The fluvial process of the Yalu Tsangpo River occurs concurrently with the uplift of the Qinghai-Tibet ***,the river exhibits unique features in morphology and sediment *** investigations were performed from 2009–2011and the depth of the interface between the sediment deposits and bed rock was detected with an electromagnetic imaging system(EH4)at 29 cross *** deposits were sampled along the Yalu Tsangpo valley from Xietongmen to the Yalu Tsangpo *** results show that a huge amount of sediment has been deposited in four wide valley sections because the uplift rate in these sections was lower than that in the downstream gorge sections over the past million *** 518 billion m3of gravel and sand have been stored in the high mountain river valleys,which has changed the V-shaped mountain river valley into a U-shaped wide river valley in the four *** the sections with high uplift rates the river bed is incised and has formed gorges and the Yalu Tsangpo Canyon.

关键词： Yalu Tsangpo River sediment deposits uneven uplift himalaya wide valley

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Algorithm-based care for early recognition and management of complications after pancreatic resection:toward standardization of postoperative care

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Hepatobiliary surgery and Nutrition 2022年第5期11卷 718-720页

作者： charles de Ponthaud sébastien Gaujoux Department of Hepato-Biliary and Pancreatic surgery and Liver Transplantation AP-HPPitié-Salpêtrière HospitalParisFrance sorbonne University ParisFrance

This stepped-wedge cluster randomized study(1)included all pancreatectomies performed from 17 Dutch pancreatic surgery centers(all realizing>20 pancreaticoduodenectomies per year)over 22 *** aim was to demonstrate the value of an algorithm for the early diagnosis and management of postoperative *** algorithm determined when to do abdominal computed tomography(CT)scan,radiological drainage,start antibiotic treatment,and remove abdominal *** was calculated every day from postoperative day 3 to *** primary endpoint was a composite of bleeding that required invasive intervention,organ failure and 90-day mortality.

关键词： postoperative diagnosis remove

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An Analysis of Liberia’s Vulnerability to Climate Change in the Context of Least Developed Countries (LDCs): A Review

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American Journal of Climate Change（美国气候变化期刊） 2024年第2期 230页

作者： charles Flomo Togbah

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sino-U.s. partnerships in research, education, and patient care：The experience of the University of Pittsburgh and UPMC

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science China(Life sciences) 2017年第10期60卷 1150-1156页

作者： s.Levine Margaret C.McDonald charles E.Bogosta University of Pittsburgh schools of the Health sciences Pittsburgh PA 15261 USA University of Pittsburgh Medical Center (UPMC) Pittsburgh PA 15219 USA

In 2011, the University of Pittsburgh school of Medicine(UPsOM) and Tsinghua University formed a partnership to further the education of Tsinghua medical students. These students come to UPsOM as visiting research scholars for two years of their eight-year MD curriculum. During this time, the students, who have completed four years at Tsinghua, work full-time in medical school laboratories and research programs of their choice, essentially functioning as graduate students. In their first two months in Pittsburgh, the scholars have a one-week orientation to biomedical research, followed by two-week rotations in four labs selected on the basis of the scholars' scientific interests, after which they choose one of these labs for the remainder of the two *** labs may be in basic science departments, basic science divisions of clinical departments, or specialized centers that focus on approaches like simulation and modeling. The Tsinghua students also have a brief exposure to clinical medicine. UPsOM has also formed a similar partnership with Central south University Xiangya school of Medicine in Changsha, Hunan Province. The Xiangya students come to UPsOM for two years of research training after their sixth year and, thus, unlike the Tsinghua students,have already completed their clinical rotations. UPsOM faculty members have also paved the way for UPMC(University of Pittsburgh Medical Center), UPsOM's clinical partner, to engage with clinical centers in China. Major relationships involving advisory, training, managerial, and/or equity roles exist with Xiangya International Medical Center, KingMED Diagnostics, First Chengmei Medical Industry Group, and Macare Women's Hospital. Both UPsOM and UPMC are actively exploring other clinical and academic opportunities in China.

关键词： medical education research training partnership

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In-vitro digestibility,protein digestibility corrected amino acid,and sensory properties of banana-cassava gluten-free pasta with soy protein isolate and egg white protein addition

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Food science and Human Wellness 2023年第2期12卷 520-527页

作者： Adetiya Rachman Margaret ABrennan James Morton Damir Torrico charles s.Brennan Department of Wine Food and Molecular BiosciencesLincoln UniversityChristchurch 7647New Zealand Riddet Research Institute Palmerston North 4442New Zealand Indonesia Institute for Agricultural Research and Development Jakarta 12540Indonesia

soy protein isolate and egg white protein were added to cassava-banana gluten-free pasta and the effects on the nutritional quality,digestibility properties,protein digestibility corrected amino acid(PDCAA),and sensory acceptance of the pasta was ***-cassava composite flour(75:25)was blended with soy protein isolate or egg white protein at the following rates:0,5,10,and 15 g/100 g *** pasta samples were analysed for total phenolic content(TPC),antioxidant activity,amino acid profiles,protein content,starch digestibility,protein digestibility and protein digestibility corrected amino acid score(PDCAAs).Addition of both proteins decreased starch digestibility,increased protein digestibility,improved the balance of the amino acid profile,and PDCAAs whereas only soy protein isolate enhanced the TPC and antioxidant capacity of the banana-cassava *** egg white protein-fortified banana-cassava pasta had better customer acceptance and purchase intent than soy protein isolate inclusion.

关键词： Banana flour Cassava flour Gluten-free pasta Digestibility properties Amino acid sensory evaluation

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Implied fractional hazard rates and default risk distributions

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Probability, Uncertainty and Quantitative Risk 2017年第1期2卷 21-34页

作者： charles s.Tapiero Pierre Vallois Topfer Chair Distinguished Professor of Financial Engineering and Technology Management Department of Finance and Risk EngineeringNew York University Tandon School of Engineering6 Metro Tech22201 BrooklynNew YorkUSA Universite de Lorraine Institut de Mathematiques Elie Cartan de LorraineINRIA.BIGSCNRS UMR 7502 BP 239F-54506Vandoeuvre-Les-NancyFrance

Default probability distributions are often defined in terms of their conditional default probability distribution,or their hazard *** their definition,they imply a unique probability density *** applications of default probability distributions are varied,including the risk premium model used to price default bonds,reliability measurement models,insurance,*** probability density functions(FPD),however,are not in general conventional probability density functions(Tapiero and Vallois,Physica A,.***.462:1161–1177,2016).As a result,a fractional FPD does not define a fractional hazard ***,a fractional hazard rate implies a unique and conventional *** example,an exponential distribution fractional hazard rate implies a Weibull probability density function while,a fractional exponential probability distribution is not a conventional distribution and therefore does not define a fractional hazard *** purpose of this paper consists of defining fractional hazard rates implied fractional distributions and to highlight their usefulness to granular default risk *** of such an approach are *** example,pricing default bonds,pricing complex insurance contracts,as well as complex network risks of various granularity,that have well defined and quantitative definitions of their hazard rates.

关键词： function. fractional bonds

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Gottfried Konecny:the ambassador of photogrammetry and remote sensing for 75 years

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Geo-spatial Information science 2021年第1期24卷 27-32,I0006页

作者： charles K.Toth Department of Civil Environmental and Geodetic EngineeringThe Ohio State UniversityColumbusOHUSA

A 90th birthday would be a milestone celebration for any person,but exceptionally rare if the person is still active after 75 years of working and serving the photogrammetric and remote sensing communities *** unprecedented career is the motivation to reflect on the technological developments of the past 75 years in the light of Gottfried Konecny’s lifetime achievements.I started to get to know Gottfried not long before he officially retired from the Institute for Photogrammetry and Engineering surveys in ***,I was not even born when he,as a young and talented scholar supported by the Fulbright scholarship from the Us Government,arrived at the Ohio state University(OsU),which has been my professional home for three *** the second half of Gottfried’s 75-year career,the technological changes have been phenomenal,and,furthermore,shown an accelerating trend in the past few *** is absolutely remarkable how Gottfried has been able to keep up with these rapid changes and advancing technologies and exploits them for mapping and,in general,for all the users of the geospatial field at ***,his open-minded and kind personality has been always a major plus to his technical skills and experiences,and ultimately helped him assist many colleagues to advance their careers,and along the way developed and increased the use of geospatial data and systems in support of many countries worldwide.

关键词： Photogrammetry remote sensing space observation

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