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Case series on multimodal endoscopic therapy for gastric antral vascular ectasia, a tertiary center experience

World Journal of Gastrointestinal Endoscopy 2018年第1期10卷 30-36页

作者： Tasnia Matin Mohammed Naseemuddin Mohamed Shoreibah Peng Li Kondal Kyanam Kabir Baig charles mel wilcox Shajan Peter Internal Medicine UAB Hospital Division of Gastroenterology University of Alabama School of Medicine Department of Gastroenterology Emory Division of Gastroenterology Uni-versity of Alabama at Birmingham School of Public Health University of Alabama at Birmingham

AIM To study and describe patients who underwent treatment for gastric antral vascular ectasia(GAVE) with different endoscopic treatment *** We reviewed patients with GAVE who underwent treatment at University of Alabama at Birmingham between March 1, 2012 and December 31, 2016. Included patients had an endoscopic diagnosis of GAVE with associated upper gastrointestinal bleeding or iron deficiency *** Seven out of 15 patients had classic watermelon description for GAVE, 1/15 with diffuse/honeycomb pattern and 6/15 with nodular GAVE per EGD description. Seven out of 15 patients required multimodal treatment. Four out of six of patients with endoscopically nodular GAVE required multimodal therapy. Overall, mean pre-and post-treatment hemoglobin(Hb) values were 8.2 ± 0.8 g/dL and 9.7 ± 1.6 g/dL, respectively(P ≤ 0.05). Mean number of packed red blood cells transfusions before and after treatment was 3.8 ± 4.3 and 1.2 ± 1.7(P ≤ 0.05), *** Patients with nodular variant GAVE required multimodal approach more frequently than non-nodular variants. Patients responded well to multimodal therapy and saw decrease in transfusion rates and increase in Hb concentrations. Our findings suggest a multimodal approach may be beneficial in nodular variant GAVE.

关键词： Gastric antral vascular ectasia Upper GI bleed Radiofrequency ablation Endoscopic band ligation Argon plasma coagulation

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Cluster size distribution of cancer cells in blood using stopped-flow centrifugation along scale-matched gaps of a radially inclined rail

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Microsystems & Nanoengineering 2015年第1期1卷 97-105页

作者： Macdara Glynn charles Nwankire Kate Lemass David J.Kinahan Jens Ducrée Biomedical Diagnostics Institute National Centre for Sensor ResearchSchool of Physical SciencesDublin City UniversityIreland

There is increasing evidence that,in addition to their presence,the propensity of circulating tumour cells to form multi-cellular clusters bears significant information about both cellular resistance to chemotherapy and overall *** present a novel two-stage,stopped-flow,continuous centrifugal sedimentation strategy to measure the size distributions of events(defined here as cells or clusters thereof)in a blood *** off-chip removal of red blood cells,healthy white blood cells are sequestered by *** purified events are then resolved along a radially inclined rail featuring a series of gaps with increasing width,each connected to a designated outer collection *** isolation of candidate events independent of targetspecific epitopes is successfully demonstrated for HL60(EpCAM positive)and sk-mel28(EpCAM negative)cells using identical protocols and *** propensity to form clusters was quantified for a number of cell lines,showing a negligible,moderate or elevated tendency towards cluster *** show that the occupancy distribution of the collection bins closely correlates with the range of cluster sizes intrinsic to the specific cell line.

关键词： centrifugal microfluidics lab-on-a-disc cancer diagnostics cellular clustering

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Sanitary Quality of the Meals Served in the Canteens and Vicinity of the Lagoon Mother and Child University Hospital Centre and National Hospital and University Centre Hubert Koutoukou Maga of Cotonou (Benin)

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Open Journal of Preventive Medicine 2023年第5期13卷 183-197页

作者： Moussiliou Paraïso Cyriaque Comlan Degbey Yasmine Bakary Ozavino Colette Azandjeme charles Sossa-Jerome Regional Institute of Public Health University of Abomey-Calavi Abomey-Calavi Benin

Background: Food safety is an integral part of food security. It refers to the protection of the food supply against risks of microbial, chemical and physical origin at every stage of the food chain. The study aimed to investigate the sanitary quality of meals served in the canteens and vicinity of the Lagoon Mother and Child University Hospital Centre (CHU-mel) and National Hospital and University Centre Hubert Koutoukou Maga (CNHU-HKM) of Cotonou. Methods: It was a cross-sectional with a data collection period from 16 March to 22 April 2021. There were 32 vendors surveyed and 40 meals sampled for microbiological examination. We collected data on the vendors’ socio-demographic characteristics, working environment, health status, knowledge and food hygiene practices. Results: About 83% of the meals contained pathogenic microorganisms. All meals had a temperature from 4°C to 60°C called the “danger zone”. The level of knowledge about food hygiene was low in 65.7% of the vendors. About 47% had poor personal and clothing hygiene, food storage and service practices. Conclusion: These results show that the meals sold in the CHU-mel and CNHU-HKM could present a health risk for the consumer. There is a need for improvement of the sanitary quality of the meals delivered in the canteens and vicinity of these hospitals.

关键词： Sanitary Quality Meals Canteens CHU-mel CNHU-HKM Benin

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