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Diffusion tensor imaging of optic nerve and optic radiation in primary chronic angle-closure glaucoma using 3T magnetic resonance imaging

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International Journal of Ophthalmology(English edition) 2015年第5期8卷 975-979页

作者： Qiu-Juan zhang Dong Wang Zhi-Lan Bai Bai-chao Ren Xiao-Hui Li Department of Radiology the Second Affiliated Hospital of Xi'an Jiaotong University Department of Ophthalmology the Second Affiliated Hospital of Xi'an Jiaotong University

AIM: To evaluate the value of quantitative diffusion tensor imaging (DTI) in assessing the axonal and myelin damage of the optic nerves and optic radiations in patients with chronic primary angle -closure glaucoma (PACG) by using high -field magnetic resonance (MR) imaging (3T). METHODS: Twenty patients with bilateral chronic PACG and twenty age - and sex matched disease -free control subjects were enrolled. Conventional MRI and DTI were performed on all subjects using 3T MR scanner. Mean diffusivity (MD), fractional anisotropy (FA), axial diffusivities (AD) and radial diffusivities (RD) of each optic nerve and each optic radiation were measured by using post -processing software of DTI studio 2.3, and then compared between left eyes and right eyes and between patients group and control group. The pairedsample t- test were used. RESULTS: There was no abnormality in the shape and signal intensity of the optic nerves and optic radiations in patients group and control group on the conventional MRI. No significant differences were observed in the FA, MD, AD and RD between the right and left optic nerves and optic radiations within patients group and control group (P>0.05). The optic nerves and optic radiations of patients with chronic PACG, as compared with control subjects, had significantly higher MD, AD, RD and significantly lower FA (P<0.05). CONCLUSION: The diffusivity of optic nerves and optic radiations in chronic PACG group showed abnormal and diffusivity parameters could be used markers of axonal and myelin injury in glaucoma.

关键词： primary angle-closure glaucoma chronic optic nerve and optic radiation diffusion tensor imaging magnetic resonance imaging

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Microstructure and properties of Al_(2)O_(3)-ZrO_(2)-TiO_(2)composite coatings prepared by plasma spraying

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Rare Metals 2021年第7期40卷 1825-1834页

作者： Peng-yue Gao Yu-Duo Ma Wen-Wei Sun Yong Yang Chen zhang Yu-Hang Cui Yan-Wei Wang Yan-Chun Dong School of Materials Science and Engineering Hebei University of TechnologyTianjin 300132China Key Laboratory for New Type of Functional Materials in Hebei Province Tianjin 300132China State Key Laboratory of Reliability and Intelligence of Electrical Equipment Tianjin 300132China

Al_(2)O_(3)-ZrO_(2)-TiO_(2)coatings were successfully prepared by plasma spraying Al_(2)O_(3)-ZrO_(2)composite powders with and without TiO_(2)*** effects of TiO_(2)on the phase composition,microstructure and properties of the Al_(2)O_(3)-ZrO_(2)coating were *** results show that the Al_(2)O_(3)-ZrO_(2)-TiO_(2)composite powder was composed of t-ZrO_(2),a-Al_(2)O_(3),m-ZrO_(2)and rutile,while the Al_(2)O_(3)-ZrO_(2)-TiO_(2)composite coating consisted of t-ZrO_(2),a-Al_(2)O_(3)and c-Al_(2)O_(3).The diffraction peaks of TiO_(2)could not be detected in the Al_(2)O_(3)-ZrO_(2)-TiO_(2)coating even up to10 wt%TiO_(2)*** reason may be that TiO_(2)was dissolved in the amorphous phase or formed solid solution with c-Al_(2)O_(3)phase in the coating during *** with the Al_(2)O_(3)-ZrO_(2)coating,the as-prepared Al_(2)O_(3)-ZrO_(2)-TiO_(2)coating had denser microstructure,less microcracks and more amorphous *** density of the Al_(2)O_(3)-ZrO_(2)-TiO_(2)coating increased with the increase of TiO_(2)*** Al_(2)O_(3)-ZrO_(2)-10 wt%TiO_(2)coating had the most uniform and dense microstructure,possessed higher toughness,adhesive strength and wear resistance compared with the Al_(2)O_(3)-ZrO_(2)coating,which was due to its lower porosity and more uniform microstructure.

关键词： Al_(2)O_(3)-ZrO_(2) Composite coatings Plasma spraying TiO_(2)

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The distribution characteristics of the flows in the near-Earth region: TC-1 observational results

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Chinese Science Bulletin 2007年第23期52卷 3267-3271页

作者： zhang LingQian LIU ZhenXing WANG JiYe MA ZhiWei PU ZhuYin SHEN chao GUO JiuLing Center for Space and Applied Research Chinese Academy of Sciences Beijing 100080 China College of Physics and Electronic Engineering Central University for Nationalities Beijing 100081 China Institute of Plasma Physics Chinese Academy of Sciences Hefei 230031 China School of Earth and Space Science Peking University Beijing 100871 China Modern Education Technology Center Peking University Beijiing 100871 China

TC-1 observational results clearly indicate that the velocity of the flows in the near-Earth region is de- pendent on the satellite location. The flow speed decreases while satellite moves close to the Earth. The plasma flow in the region close to the Earth tends to drift into the midnight region from the dawn and dusk region while the flow in the region away from the Earth shows an opposite drift. The obser- vational results also show that the tailward flows are mainly located in the plasma sheet boundary while the earthward flow becomes dominant in the plasma sheet. It is found that both the strong tailward and earthward flows are distributed in the region around X= -11Re, which coincides with the trigger region of the substorm onset. Hence, it may suggest that the flows are related with the trigger of the substorm onset. In addition, the BBFs coming from the mid-tail maily distributed in the region where X<-9RE and |Z|<3RE that differs from the convection.

关键词：地球磁尾地形分布数据收集

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Whole-brain CT Perfusion at Admission and During Delayed Time-window Detects the Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage

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Current Medical Science 2023年第2期43卷 409-416页

作者： Feng YOU Wen-juan TANG chao zhang Ming-quan YE Xing-gen FANG Yun-feng ZHOU Department of Radiology the First Affiliated Hospital of Wannan Medical CollegeWuhu241001China Department of Radiology Affiliated Hangzhou First People’s HospitalHangzhou310000China Department of Radiology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430022China School of Medical Information Wannan Medical CollegeWuhu241001China Department of Neurosurgery the First Affiliated Hospital of Wannan Medical CollegeWuhu241001China

Objective To evaluate the utility of computed tomography perfusion(CTP)both at admission and during delayed cerebral ischemia time-window(DCITW)in the detection of delayed cerebral ischemia(DCI)and the change in CTP parameters from admission to DCITW following aneurysmal subarachnoid *** Eighty patients underwent CTP at admission and during *** mean and extreme values of all CTP parameters at admission and during DCITW were compared between the DCI group and non-DCI group,and comparisons were also made between admission and DCITW within each *** qualitative color-coded perfusion maps were ***,the relationship between CTP parameters and DCI was assessed by receiver operating characteristic(ROC)*** With the exception of cerebral blood volume(P=0.295,admission;P=0.682,DCITW),there were significant differences in the mean quantitative CTP parameters between DCI and non-DCI patients both at admission and during *** the DCI group,the extreme parameters were significantly different between admission and *** DCI group also showed a deteriorative trend in the qualitative color-coded perfusion *** the detection of DCI,mean transit time to the center of the impulse response function(Tmax)at admission and mean time to start(TTS)during DCITW had the largest area under curve(AUC),0.698 and 0.789,*** Whole-brain CTP can predict the occurrence of DCI at admission and diagnose DCI during *** extreme quantitative parameters and qualitative color-coded perfusion maps can better reflect the perfusion changes of patients with DCI from admission to DCITW.

关键词： aneurysmal subarachnoid hemorrhage delayed cerebral ischemia admission time window computed tomography perfusion

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板料变形的投影栅三维快速测量技术研究

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塑性工程学报 2005年第1期12卷 5-9页

作者：张吴明钟约先袁朝龙清华大学机械工程系北京100084

目前, 国内外研究的物体形面光学三维测量系统, 多用于静态物体的三维测量, 测量时间较长。本文研究了一种投影栅三维形面快速测量系统, 可应用于处于动态状态的物体的三维测量。文中介绍了其原理、相展开以及双CCD相位周期匹配等关键技... 详细信息

目前, 国内外研究的物体形面光学三维测量系统, 多用于静态物体的三维测量, 测量时间较长。本文研究了一种投影栅三维形面快速测量系统, 可应用于处于动态状态的物体的三维测量。文中介绍了其原理、相展开以及双CCD相位周期匹配等关键技术, 并且应用该系统对汽车侧围板变形进行测量。精度验证表明, 系统在测量范围内误差为10μm量级, 可用于工业快速测量领域。

关键词：快速三维形面测量投影栅相位法视觉过程数字相关

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FGFR2-TSC22D1,a novel FGFR2 fusion gene identified in a patient with colorectal cancer:A case report

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World Journal of Clinical Cases 2021年第23期9卷 6867-6871页

作者： Xiao-Ming Kao Xi Zhu Jun-Ling zhang Shi-Qing Chen chao-Gang Fan Research Institure of General Surgery Jinling HospitalNanjing 210002Jiangsu ProvinceChina Department of Medical 3D Medicines Inc.Shanghai 201114China Department of General Surgery The Affiliated BenQ Hospital of Nanjing Medical UniversityNanjing 210002Jiangsu ProvinceChina

BACKGROUND The FGFR signaling pathway is activated in multiple tumor types through gene amplifications,single base substitutions,or gene *** FGFR gene fusions may represent candidate targets for the development of tyrosine kinase *** SUMMARY Herein,we report a patient with colorectal cancer(CRC)harboring a novel FGFR2 fusion gene.A 59-year-old man felt discomfort in his right upper abdomen with loss of appetite for 6 *** abdominal computed tomography scan revealed the existence of a space-occupying lesion in the ascending *** pathological diagnosis was a poorly differentiated *** biopsy specimen was subjected to next-generation sequencing analysis,and a novel FGFR2-TSC22D1 fusion with complete kinase structure of FGFR2 protein was *** We report the first case of CRC harboring FGFR2-TSC22D1,which enriches the FGFR2 fusion ***2 inhibitors might be effective in the later treatment for this patient.

关键词： FGFR2-TSC22D1 Colorectal cancer Next-generation sequencing Case report

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Physiological response of four wolfberry (Lycium Linn.) species under drought stress

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Journal of Integrative Agriculture 2018年第3期17卷 603-612页

作者： ZHAO Jian-hua LI Hao-xia zhang Cun-zhi AN wei YIN yue WANG Ya-jun CAO You-long National Wolfberry Engineering Research Center Ningxia Academy of Agriculture and Forestry Sciences Yinchuan 750002 P. R. China Desertification Control Research Institute Ningxia Academy of Agriculture and Forestry Sciences Yinchuan 750002 P.R.China Ningxia Professional Technology College Yinchuan 750021 P.R. China

We studied gas-exchange, chlorophyll pigments, lipid peroxidation, antioxidant enzymes, and biomass partitioning responses in seedlings of four wolfberry species （Lycium chinense Mill. var. potaninii （Pojark.） A. M. Lu, Lycium chinense Mill., Lycium barbarum L., and Lycium yunnanense Kuang ＆ A. M. Lu） under four water supply regimes. In all four species, drought affected seedlings in terms of chlorophyll content, net photosynthesis rate （Pn）＇ transpiration rate （E）, and lipid peroxidation. Drought also increased some antioxidant enzyme activities, such as peroxidase （POD）, catalase （CAT）, superoxide dismutase （SOD）, and ascorbate peroxidase （APX）. Significant changes in dry biomass partitioning also occurred in response to water stress. In particular, dry biomass of leaves and fruits decreased significantly. L. chinense Mill. and L. barbarum L. possessed greater drought tolerance and exhibited superior antioxidant processing ability and other related physiological traits compared to the other two species. L. chinense Mill. was the most tolerant to all levels of drought. In contrast,L, yunnanense Kuang ＆ A. M. Lu was more affected by water supply and had the lowest resistance to drought stress. These findings would provide some important information regarding genetic resources for future forest tree improvement in relation to drought tolerance.

关键词： drought Lycium Linn. chlorophyll fluoresc.ence osmotic adjustment antioxidant respond dry matter allocation

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SemiSynBio:A new era for neuromorphic computing

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Synthetic and Systems Biotechnology 2024年第3期9卷 594-599页

作者： Ruicun Liu Tuoyu Liu Wuge Liu Boyu Luo Yuchen Li Xinyue Fan Xianchao zhang Wei Cui yue Teng State Key Laboratory of Pathogen and Biosecurity Beijing Institute of Microbiology and EpidemiologyAcademy of Military Medical SciencesBeijing100071China Institute of Information Network and Artificial Intelligence Jiaxing UniversityJiaxing314001China South China University of Technology Guangzhou510641China

Neuromorphic computing has the potential to achieve the requirements of the next-generation artificial intelligence(AI)systems,due to its advantages of adaptive learning and parallel ***,biocomputing has seen ongoing development with the rise of synthetic biology,becoming the driving force for new generation semiconductor synthetic biology(SemiSynBio)***-based biomolecules could potentially perform the functions of Boolean operators as logic gates and be used to construct artificial neural networks(ANNs),providing the possibility of executing neuromorphic computing at the molecular ***,we briefly outline the principles of neuromorphic computing,describe the advances in DNA computing with a focus on synthetic neuromorphic computing,and summarize the major challenges and prospects for synthetic neuromorphic *** believe that constructing such synthetic neuromorphic circuits will be an important step toward realizing neuromorphic computing,which would be of widespread use in biocomputing,DNA storage,information security,and national defense.

关键词： Neuromorphic computing Synthetic biology Biocomputing Artificial intelligence Neuromorphic genetic circuits

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New evidence for the links between the local water cycle and the underground wet sand layer of a mega-dune in the Badain Jaran Desert, China

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Journal of Arid Land 2014年第4期6卷 371-377页

作者： Jun WEN ZhongBo SU TangTang zhang Hui TIAN YiJian ZENG Rong LIU yue KANG Rogier van der VELDE Key Laboratory of Land Surface Process and Climate Change in Cold and Arid Regions Cold and Arid Regions Environmental and Engineering Research Institute Chinese Academy of Sciences Faculty of Geo-Information Science and Earth Observation (ITC) University of Twente

Scientists and the local government have great concerns about the climate change and water resources in the Badain Jaran Desert of western China. A field study for the local water cycle of a lake-desert system was conducted near the Noertu Lake in the Badain Jaran Desert from 21 June to 26 August 2008. An underground wet sand layer was observed at a depth of 20–50 cm through analysis of datasets collected during the field experiment. Measurements unveiled that the near surface air humidity increased in the nighttime. The sensible and latent heat fluxes were equivalent at a site about 50 m away from the Noertu Lake during the daytime, with mean values of 134.4 and 105.9 W/m2 respectively. The sensible heat flux was dominant at a site about 500 m away from the Noertu Lake, with a mean of 187.7 W/m2, and a mean latent heat flux of only 26.7 W/m2. There were no apparent differences for the land surface energy budget at the two sites during the night time. The latent heat flux was always negative with a mean value of –12.7 W/m2, and the sensible heat flux was either positive or negative with a mean value of 5.10 W/m2. A portion of the local precipitation was evaporated into the air and the top-layer of sand dried quickly after every rainfall event, while another portion seeped deep and was trapped by the underground wet sand layer, and supplied water for surface psammophyte growth. With an increase of air humidity and the occurrence of negative latent heat flux or water vapor condensation around the Noertu Lake during the nighttime, we postulated that the vapor was transported and condensed at the lakeward sand surface, and provided supplemental underground sand pore water. There were links between the local water cycle, underground wet sand layer, psammophyte growth and landscape evolution of the mega-dunes surrounding the lakes in the Badain Jaran Desert of western China.

关键词： mega-dune water cycle observation wet sand layer Badain Jaran Desert

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Youxi: A Historic County of China

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China & The World Cultural Exchange 2011年第11期77卷 36-38页

作者： zhang yue

County has played an important role in the history of China since it was first established as a basic administrative unit in the Qin Dynasty more than 2000 years ago. Historic counties have not only performed administrative and economic functions but also carried and preserved basic information about culture and traditions of China. Not long ago, the Photographic Exhibition on the Cultural Heritage of Historic Counties of China, organized by China Cultural Relics Protection Foundation in partnership with the Palace Museum and China Institute of Toponymy, was held at the Forbidden City, displaying photographs on the cultures and traditions of the first 16 Historic Counties of China, with an objective to enhance the public’s awareness of the conservation of cultural heritage in these historic counties. Our magazine will cover each of these chosen historic counties in each issue.

关键词：中国历史尤溪环境水文学

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