Whole-brain CT Perfusion at Admission and During Delayed Time-window Detects the Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage
作者机构：Department of Radiologythe First Affiliated Hospital of Wannan Medical CollegeWuhu241001China Department of RadiologyAffiliated Hangzhou First People’s HospitalHangzhou310000China Department of RadiologyUnion HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430022China School of Medical InformationWannan Medical CollegeWuhu241001China Department of Neurosurgerythe First Affiliated Hospital of Wannan Medical CollegeWuhu241001China
出 版 物：《Current Medical Science》 (当代医学科学（英文）)
年 卷 期：2023年第43卷第2期
页 面：409-416页
核心收录：
基 金：supported by the National Natural Science Foundation of China Research on Brain Magnetic Resonance Image Segmentation Based on Particle Computation(No.61672386)
主 题：aneurysmal subarachnoid hemorrhage delayed cerebral ischemia admission time window computed tomography perfusion
摘 要：Objective To evaluate the utility of computed tomography perfusion(CTP)both at admission and during delayed cerebral ischemia time-window(DCITW)in the detection of delayed cerebral ischemia(DCI)and the change in CTP parameters from admission to DCITW following aneurysmal subarachnoid *** Eighty patients underwent CTP at admission and during *** mean and extreme values of all CTP parameters at admission and during DCITW were compared between the DCI group and non-DCI group,and comparisons were also made between admission and DCITW within each *** qualitative color-coded perfusion maps were ***,the relationship between CTP parameters and DCI was assessed by receiver operating characteristic(ROC)*** With the exception of cerebral blood volume(P=0.295,admission;P=0.682,DCITW),there were significant differences in the mean quantitative CTP parameters between DCI and non-DCI patients both at admission and during *** the DCI group,the extreme parameters were significantly different between admission and *** DCI group also showed a deteriorative trend in the qualitative color-coded perfusion *** the detection of DCI,mean transit time to the center of the impulse response function(Tmax)at admission and mean time to start(TTS)during DCITW had the largest area under curve(AUC),0.698 and 0.789,*** Whole-brain CTP can predict the occurrence of DCI at admission and diagnose DCI during *** extreme quantitative parameters and qualitative color-coded perfusion maps can better reflect the perfusion changes of patients with DCI from admission to DCITW.
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