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Chinese Journal of Integrative Medicine 2018年第10期24卷 789-793页

作者： CHEN Wei LI En-chang zheng Wei-rong Center for Health and Bioethics Wenzhou Medical University

From the event of TU You-you winning the Nobel Prize, this paper briefly reviewed the history of formation and development of policies on Chinese medicine （CM） in China. On the basis of analyzing the causes of policies on CM, it is believed that policies on CM in China may have 4 kinds of enlightenments to the development of complementary and alternative medicine （CAM） in the world. Forming the political advantages of policy-making by main leaders of the country attaching importance to CAM; implementing a diversified health care system policy for the goal of maximizing people＇s health interests; ensuring development of CAM by the coerciveness of law and the timeliness of policy adjustment; and promoting the protection and mining, sorting out and improving of CAM based on open and comprehensive policies.

关键词： complementary and alternative medicine Chinese medicine policies on Chinese medicine integrated Chinese and Western medicine

Symmetry Breaking for Black-Scholes Equations

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Communications in Theoretical Physics 2007年第6期47卷 995-1000页

作者： YANG Xuan-Liu ZHANG Shun-Li QU chang-zheng School of Economics and Management Tsinghua University Beijing 100084 China Center for Nonlinear Studies Northwest University Xi＇an 710069 China Department of Mathematics Northwest University Xi＇an 710069 China

Black-Scholes equation is used to model stock option pricing. In this paper, optimal systems with one to four parameters of Lie point symmetries for Black-Scholes equation and its extension are obtained. Their symmetry breaking interaction associated with the optimal systems is also studied. As a. result, symmetry reductions and corresponding solutions for the resulting equations are obtained.

关键词： Black-Scholes equation symmetry optimal system symmetry breaking solution

Sensitivity study of searching for τ^-→γμ^- at HIEPA

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Science Bulletin 2016年第4期61卷 307-312页

作者： Yu-Bo Li Cheng-Ping Shen chang-zheng Yuan School of Physics and Nuclear Energy Engineering Beihang University Institute of High Energy Physics Chinese Academy of Sciences

The charged lepton flavor violation process is a clean and sensitive probe of new physics beyond the Standard Model. A sensitivity study is performed to the process τ^-→γμ^- based on a 3 fb^(-1) inclusive Monte Carlo sample of e^+e^- collisions at a center-of-mass energy of4.26 or 4.6 Ge V, in the framework of the BESIII software system. The 90 % confidence level upper limits on B(τ^-→γμ^-) are estimated assuming no signal is produced. We also obtain the sensitivity on B(τ^-→γμ^-) as a function of the integrated luminosity, to serve as a reference for the HIEPA being proposed in China. It is found that 6.34 ab^(-1) are needed to reach the current best upper limit of 4:4 10^(-8) and about 2510 ab^(-1) are needed to reach a sensitivity of 10^(-9) if the detector design is similar to that of BESIII.

关键词： Charged lepton flavor violation Branching fraction New physics

Analysis of bending and buckling of pre-twisted beams:A bioinspired study

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Acta Mechanica Sinica 2014年第4期30卷 507-515页

作者： Zi-Long Zhao Hong-Ping Zhao zheng chang Xi-Qiao Feng Institute of Biomechanics and Medical Engineering AML Department of Engineering MechanicsTsinghua University Center for Nano and Micro Mechanics Tsinghua University

Twisting chirality is widely observed in artificial and natural materials and structures at different length scales. In this paper, we theoretically investigate the effect of twisting chiral morphology on the mechanical properties of elas- tic beams by using the Timoshenko beam model. Particular attention is paid to the transverse bending and axial buckling of a pre-twisted rectangular beam. The analytical solution is first derived for the deflection of a clamped-free beam under a uniformly or periodically distributed transverse force. The critical buckling condition of the beam subjected to its self- weight and an axial compressive force is further solved. The results show that the twisting morphology can significantly improve the resistance of beams to both transverse bending and axial buckling. This study helps understand some phenomena associated with twisting chirality in nature and provides inspirations for the design of novel devices and structures.

关键词： Twisting chirality. Timoshenko beam. Bending.Euler buckling · Bionics

Fabrication of wear-resistant layers with lamellar eutectic structure by laser surface alloying using the in situ reaction between Cr and B_4C

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International Journal of Minerals,Metallurgy and Materials 2016年第11期23卷 1294-1301页

作者： You-zheng Sun Jin-bao Li Daniel Wellburn chang-sheng Liu Key Laboratory for Anisotropy and Texture of Materials (Ministry of Education) Northeastern University

To improve the wear resistance of Cr5 steel, wear-resistant layers with lamellar eutectic microstructure were fabricated by laser surface alloying（LSA）, which is dependent on the in situ reaction between Cr and B_4C. Our results indicated that the hypoeutectic structures of the LSA layers were divided into interdendritic eutectic structures and dendrites. The area fraction of the eutectic structures increased with increasing laser scanning speed, which improved the hardness and wear resistance of the LSA layers. The average hardness of the LSA layer prepared at a scanning speed of 8 mm/s was HV_（0.2） 883.9, which was 1.8 times greater than that of the traditional quenched layer（approximately HV 480）. After sliding for 659.4 m, the specimen prepared at a scanning speed of 8 mm/s exhibited a volume loss of 0.0323 mm^3, which was only 29.5% of the volume loss of the traditional quenched specimen.

关键词： eutectic wear resistance laser alloying hardness

Scenario-based analysis and probability assessment of sub-synchronous oscillation caused by wind farms with direct-driven wind generators

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Journal of Modern Power Systems and Clean Energy 2019年第2期7卷 243-253页

作者： Zhi AN Chen SHEN Zetian zheng Feng LIU Xiaoqing chang Wei WEI Department of Electrical Engineering Tsinghua UniversityBeijingChina China State Key Laboratory of Power System and Generation Equipment BeijingChina Electric Power Research Institute of Sichuan Electric Power Company ChengduChina

Recently, explanations of the sub-synchronous oscillation(SSO) caused by wind farms based on directdriven wind generators(DDWGs) have been published in the literatures, in which the controller parameters of DDWGs and the system equivalent parameters play an important role. However, more than one set of parameters can cause weakly damped sub-synchronous modes. The most vulnerable and highly possible scenario is still unknown. To find scenarios that have potential oscillation risks, this paper proposes a small disturbance model of wind farms with DDWGs connected to the grid using a state-space modeling technique. Taguchi’s orthogonal array testing is introduced to generate different *** scenarios with different parameter settings that may lead to SSOs are found. A probabilistic analysis method based on the Gaussian mixture model is employed to evaluate the consistency of these scenarios with the actual accidents. Electromagnetic transient simulations are performed to verify the findings.

关键词： Direct-driven wind generator Subsynchronous oscillation Probabilistic assessment Randomness

Metabolites from marine invertebrates and their symbiotic microorganisms: molecular diversity discovery, mining, and application

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Marine Life Science & Technology 2019年第1期1卷 60-94页

作者： Lu Liu Yao-Yao zheng chang-Lun Shao chang-Yun Wang Key Laboratory of Marine Drugs the Ministry of Education of ChinaSchool of Medicine and PharmacyOcean University of ChinaQingdao 266003China Laboratory for Marine Drugs and Bioproducts Qingdao National Laboratory for Marine Science and TechnologyQingdao 266237China Single-Cell Center CAS Key Laboratory of Biofuels and Shandong Key Laboratory of Energy GeneticsQingdao Institute of Bioenergy and Bioprocess TechnologyChinese Academy of SciencesQingdao 266101China Institute of Evolution and Marine Biodiversity Ocean University of ChinaQingdao 266003China

Metabolites from marine organisms have proven to be a rich source for the discovery of multiple potent bioactive moleculeswith diverse structures. In recent years, we initiated a program to investigate the diversity of the secondary metabolites frommarine invertebrates and their symbiotic microorganisms collected from the South China Sea. In this review, representativecases are summarized focusing on molecular diversity, mining, and application of natural products from these marineorganisms. To provide a comprehensive introduction to the field of marine natural products, we highlight typical moleculesincluding their structures, chemical synthesis, bioactivities and mechanisms, structure-activity relationships as well as biogenesis. The mining of marine-derived microorganisms to produce novel secondary metabolites is also discussed through theOSMAC strategy and via partial chemical epigenetic modification. A broad prospectus has revealed a plethora of bioactivenatural products with novel structures from marine organisms, especially from soft corals, gorgonians, sponges, and theirsymbiotic fungi and bacteria.

关键词： Marine invertebrates Symbiotic microorganisms Marine natural products Molecular diversity Bioactivities Marine drugs

Charmonium and charmoniumlike states at the BESⅢ experiment

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National Science Review 2021年第11期8卷 26-38页

作者： chang-zheng Yuan Institute of High Energy Physics Chinese Academy of Sciences University of Chinese Academy of Sciences

Charmonium is a bound state of a charmed quark and a charmed antiquark,and a charmoniumlike state is a resonant structure that contains a charmed quark and antiquark pair but has properties that are incompatible with a conventional charmonium *** operating at center-of-mass energies from 2 to5 GeV,the BESⅢ experiment can access a wide mass range of charmonium and charmoniumlike states,and has contributed significantly in this *** review BESⅢ results involving conventional charmonium states,including the first observation of the M1 transition Ψ(2 S) γη(2 S) and the discovery of theΨ2(3823) state;and report on studies of charmoniumlike states,including the discoveries of the Z(3900)and Z(4020) tetraquark candidates,the resolution of the fine structure of the Y(4260) state,the discovery of the new production process e~+e~-γX(3872) and the uncovering of strong evidence for the commonality among the X(3872),Y(4260) and Z(3900) *** prospects for further research at BESⅢ and proposed future facilities are also presented.

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Long noncoding RNA AANCR modulates innate antiviral responses by blocking miR-210-dependent MITA downregulation in teleost fish,Miichthys miiuy

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Science China(Life Sciences) 2021年第7期64卷 1131-1148页

作者： Qing Chu Tianjun Xu Weiwei zheng Renjie chang Lei Zhang Laboratory of Fish Molecular Immunology College of Fisheries and Life ScienceShanghai Ocean UniversityShanghai 201306China Laboratory of Marine Biology and Biotechnology Qingdao National Laboratoiy for Marine Science and TechnologyQingdao 266237China Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources Ministiy of EducationShanghai Ocean UniversityShanghai 201306China National Pathogen Collection Center for Aquatic Animals Shanghai Ocean UniversityShanghai 201306China

Viral infection induces the initiation of antiviral effectors and cytokines which are critical mediators of innate antiviral *** critical molecular determinants are responsible for triggering an appropriate immune *** noncoding RNAs(lncRNAs)have emerged as new gene modulators involved in various biological processes,while how lncRNAs operate in lower vertebrates are still ***,we discover a long noncoding RNA,termed antiviral-associated long noncoding RNA(AANCR),as a novel regulator for innate antiviral responses in teleost *** results indicate that fish MITA plays an essential role in host antiviral responses and inhibition of Siniperca chuatsi rhabdovirus(SCRV)***-210 reduces MITA expression and suppress MITA-mediated antiviral responses,which may help viruses evade host antiviral ***,AANCR functions as a competing endogenous RNA(ceRNA)for miR-210 to control protein abundance of MITA,thereby inhibiting SCRV replication and promoting antiviral *** data not only shed new light on understanding the function role of lncRNA in biological processes in teleost fish,but confirmed the hypothesis that ceRNA networks exist widely in vertebrates.

关键词： long noncoding RNAs microRNA ceRNA MITA antiviral responses teleost fish

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炒烘结合工艺对烘青绿茶品质的影响

食品科学 2025年第1期46卷 90-99页

作者：张荣祥杜亚如张德董智杰倪德江郑时兵余志华中农业大学园艺林学学院湖北武汉430070 华中农业大学果蔬园艺作物种质创新与利用全国重点实验室湖北武汉430070 恩施职业技术学院生物工程学院湖北恩施445000 宣恩县伍台昌臣茶业有限公司湖北宣恩445500

以湖北宣恩县伍家台栽培茶一芽二、三叶鲜叶为实验原料,通过正交试验探究烘青绿茶加工过程中滚炒环节的温度、投叶量及茶叶水分含量对烘青产品品质的影响,采用主成分分析优化滚炒环节工艺参数,确定最优工艺。结果表明:综合32项指标提取... 详细信息

以湖北宣恩县伍家台栽培茶一芽二、三叶鲜叶为实验原料,通过正交试验探究烘青绿茶加工过程中滚炒环节的温度、投叶量及茶叶水分含量对烘青产品品质的影响,采用主成分分析优化滚炒环节工艺参数,确定最优工艺。结果表明:综合32项指标提取的5个主成分累计贡献率为90.06%,以构建评价函数作为评判指标,结合主效应分析得到最佳工艺参数为:滚炒环节温度(150±5)℃、投叶量2 kg、炒制后水分质量分数25%;烘青绿茶经滚炒后,感官评价结果发现其外形、香气、滋味、叶底得分较未经滚炒处理的样品均有所提高,涩味降低;茶叶条索匀整度、紧细度更好。研究显示,对于烘青绿茶产品,在加工过程中增加滚炒工艺环节对提升烘青绿茶品质具有较好效果。

关键词：烘青绿茶滚炒环节主成分分析

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