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Effect of Cooling Rate on the Formation and Morphology of (W,V)Cx in VC-doped WC–Co Cemented Carbide

Acta Metallurgica Sinica(English Letters) 2017年第2期30卷 146-155页

作者： Xiao-Ou Yi Xiang Huang chang-bin liu Dan-Qing Yi Yong Jiang bin Wang Hui-Qun liu Li-Yong Chen School of Materials Science and Engineering University of Science and Technology Beijing Beijing 100083 China School of Materials Science and Engineering Central South University Changsha 410083 China Key Laboratory of Nonferrous Materials Science and Engineering Ministry of Education Central South University Changsha 410083 China

The grain growth retardation mechanism and the effect of cooling rate on VC-doped WC–Co cemented carbides were investigated in this ***–30Co and WC–30Co–VC were prepared by powder metallurgy,liquid-phase sintering at 1400 ℃ and followed by water quenching（[150 ℃/s） or furnace cooling（＊0.083 ℃/s）.Based on the results of electron probe microanalysis（EPMA）,we found that WC concentration in the Co binder was independent of VC doping during liquid-phase sintering,hence barely contributing to the retardation of WC grain *** contrast,the（W,V）Cx phase formed at the WC/Co interfaces played a major role in retarding WC grain growth during liquid-phase *** effect of cooling rate on the morphology of（W,V）Cxwas revealed by high-resolution transmission electron microscopy（HRTEM） and energy-dispersive spectroscopy（EDS）.In the water-quenched WC–30Co–VC,（W,V）Cxprecipitates were found as thin layers at the WC/Co *** contrast,both thin layers of similar thickness and nanoparticles of（W,V）Cx were observed in the furnace-cooled *** observations listed above suggested that thin（W,V）Cxlayers were stable structures effectively suppressing the growth of WC grains and their thickness remained independent of the cooling ***（W,V）Cxnanoparticles,however,may be inhibited through rapid cooling,ensuring the VC-doped WC–Co cemented carbides desired toughness.

关键词： WC-Co VC doping (W,V)Cx Water-quenched Furnace-cooled

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Effectiveness of oral motor respiratory exercise and vocal intonation therapy on respiratory function and vocal quality in patients with spinal cord injury:a randomized controlled trial

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Neural Regeneration Research 2021年第2期16卷 375-381页

作者： Xiao-Ying Zhang Yi-Chuan Song chang-bin liu Chuan Qin Song-Huai liu Jian-Jun Li School of Rehabilitation Medicine Capital Medical UniversityBeijingChina China Rehabilitation Science Institute BeijingChina Beijing Key Laboratory of Neural Injury and Rehabilitation BeijingChina Center of Neural Injury and Repair Beijing Institute for Brain DisordersBeijingChina Music Therapy Center Department of PsychologyChina Rehabilitation Research CenterBeijingChina Department of Rehabilitation Medicine Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Department of Spinal and Neural Functional Reconstruction China Rehabilitation Research CenterBeijingChina

Singing,as a method of combining respiratory function exercise and vocal intonation therapy,provides a new direction for respiratory function exercise in patients with spinal cord *** randomized controlled trial investigated the effects of oral motor respiratory exercise and vocal intonation therapy on respiratory function and vocal quality in patients with spinal cord *** 31 included patients with spinal cord injury,18 completed the *** 18 patients were randomly assigned to undergo music therapy(intervention group,30 min/d,5 times a week,for a total of 12 weeks;n=9,7 males and 2 females;30.33±11.74 years old)or normal respiratory training(control group,n=9;8 males and 1 female;34.78±11.13 years old).Both patient groups received routine treatment *** and at 6 and 12 weeks after intervention,a standard respiratory function test,a voice test,the ***'s Respiratory Questionnaire,and a quality of life questionnaire were *** results showed that the inspiratory capacity,forced expiratory volume in 1 second,forced vital capacity,maximal mid-expiratory flow rate,sing-loud pressure level,and sustained note length were significantly increased in the intervention group compared with the control *** ***'s Respiratory Questionnaire and quality of life results of patients in the intervention group were significantly superior to those in the control *** findings suggest that oral motor respiratory exercise and vocal intonation therapy,as respiratory training methods in music therapy,are effective and valuable for improving respiratory dysfunction and vocal quality in patients with spinal cord *** study was approved by the Ethics Committee of China Rehabilitation Research Center(approval No.2019-78-1)on May 27,2019 and was registered with the Chinese Clinical Trial Registry(registration number:Chi CTR1900026922)on October 26,2019.

关键词： central nervous system clinical trial injury oral motor randomized repair respiratory exercise spinal cord

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Diffusion tensor imaging reveals brain structure changes in dogs after spinal cord injury

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中国神经再生研究：英文版 2023年第1期18卷 176-182页

作者： chang-bin liu De-Gang Yang Jun Li Chuan Qin Xin Zhang Jun liu Da-Peng Li Jian-Jun Li Department of Rehabilitation Medicine Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Department of Spinal and Neural Function Reconstruction China Rehabilitation Research CenterBeijingChina China Rehabilitation Science Institute BeijingChina Department of Neurosurgery Beijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijingChina

Based on the Wallerian degeneration in the spinal cord pathways,the changes in synaptic connections,and the spinal cord-related cellular responses that alter the cellular structure of the brain,we presumed that brain diffusion tensor imaging(DTI)parameters may change after spinal cord ***,the dynamic changes in DTI parameters remain *** established a Beagle dog model of T10 spinal cord contusion and performed DTI of the injured spinal *** found dynamic changes in DTI parameters in the cerebral peduncle,posterior limb of the internal capsule,pre-and postcentral gyri of the brain within 12 weeks after spinal cord *** then performed immunohistochemistry to detect the expression of neurofilament heavy polypeptide(axonal marker),glial fibrillary acidic protein(glial cell marker),and NeuN(neuronal marker).We found that these pathological changes were consistent with DTI parameter *** findings suggest that DTI can display brain structure changes after spinal cord injury.

关键词： spinal cord injury diffusion tensor imaging canines pathophysiology cerebrospinal structures corticospinal tract magnetic resonance imaging anisotropic fraction apparent dispersion coefficient

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Optimizing evasive maneuvering of planes using a flight quality driven model

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Science China(Information Sciences) 2024年第3期67卷 197-208页

作者： chang liu Shaoshan SUN Chenggang TAO Yingxin SHOU bin XU School of Automation Northwestern Polytechnical University Chengdu Aircraft Design & Research Institute of AVIC

This paper investigates the optimal evasive maneuver for a plane to avoid an incoming missile. To accurately model the system dynamics while improving computational efficiency, a simplified plane model based on flight quality is established. A missile model with proportional guidance is also *** problem of determining the optimal evasion plane maneuver is formulated. The Gauss pseudospectral method(GPM) is proposed as a solution to find the optimal maneuver. The optimized maneuver is validated by testing it on a high-fidelity 6-degree-of-freedom(6-DOF) model, which demonstrates the effectiveness of the proposed simplified plane model. The Monte Carlo method is employed to evaluate the capability of the plane to evade missiles in various scenarios and elucidate general principles for successful evasion.

关键词： optimal maneuver flying quality evasive strategy pursuit-evasion game air-to-air combat

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An Improved Urethral Catheterization in Female Pigs： A Pilot Study

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Chinese Medical Journal 2017年第15期130卷 1880-1881页

作者： Da-Peng Li Wen-Hao Zhang Ming-Liang Yang chang-bin liu Xin Zhang chang Cai Jian-Jun Li School of Rehabilitation Medicine Capital Medical University Beijing 100068 China Center of Neural Injury and Repair Beijing Institute for Brain Disorders Beijing 100068 China Department of Spinal and Neural Function Reconstruction Beijing Boai Hospital China Rehabilitation Research Center Beijing 100068 China Beijing Key Laboratory of Neural Injury and Rehabilitation Beijing 100068 China

With the popularity of urine flow dynamic monitoring and indwelling catheter technologies in animal experiments,the urethral catheterization has become a common technique in scientific *** miniature pig is considered as one of the major animal species used in scientific research and is increasingly being used as an alternative to a dog or monkey as the nonrodent species of choice in the preclinical toxicological testing of pharmaceuticals.[1] Since there are three acute angles bending in the urethra of the male miniature pig,and the end of the penis head is cork-screw shaped,it is difficult to implement routine urethral catheterization in male miniature ***,researchers usually implement bladder colostomies or dissections in male miniature pigs,while transurethral urethral catheterization can be implemented in female miniature *** to the existing reports,implementing transurethral urethral catheterization in female miniature pigs is seldom seen.[2] We chose 3-month-old female Bama miniature pigs in our experiments and employ the following methods：first,use a ＂V＂-shaped platform with an angle of about 30° to the horizontal plane;second,utilize a pediatric laryngoscope for deep lighting;third,bend the lower limbs and press down to the ventral *** results through transurethral urethral catheterization were achieved in the end.

关键词： Bladder Colostomy or Centesis Female Miniature Pig Urethral Catheterization

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Oxidative cyclization of allyl compounds and isocyanide: A facile entry to polysubstituted 2-cyanopyrroles

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Chinese Chemical Letters 2024年第4期35卷 330-335页

作者： Yaping Zhang Wei Zhou Mingchun Gao Tianqi liu bingxin liu chang-Hua Ding bin Xu Department of Chemistry Affiliated Nantong Hospital of Shanghai University(The Sixth People's Hospital of Nantong)Shanghai Engineering Research Center of Organ RepairInnovative Drug Research CenterSchool of MedicineShanghai UniversityShanghai 200444China State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 200032China

A facile Tf OH-catalyzed oxidative cyclization of allyl compounds and isocyanide has been developed with the assistance of DDQ, where isocyanide is used as the crucial "N" and "CN" sources. Highly functionalized 2-cyanopyrroles are constructed efficiently through a new formal [3 + 2] mode, demonstrating diverse reactivity and synthetic utility in organic chemistry. 2-Cyanopyrrole is converted into a nucleobase analogue of Remdesivir and 5H-pyrrolo[2,1-a]isoindole through a three-step or a two-step sequence, respectively. This protocol features broad substrate scope, operational simplicity and good functional group tolerance.

关键词： Isocyanide Cyanopyrrole Insertion Allyl compound Bronsted acid catalysis

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Effect of heat treatment on microstructure and mechanical properties of selective laser-melted PH13-8Mo stainless steel

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Journal of Iron and Steel Research International 2024年第4期31卷 945-955页

作者： Yuan Zhang Xiang liu chang-jun Wang chang liu School of Material Science and Engineering Kunming University of Science and TechnologyKunming 650093YunnanChina Central Iron&Steel Research Institute Co. Ltd.Beijing 100081China

PH13-8Mo stainless steel powder with high sphericity and well fluidity was prepared by the plasma rotating electrode *** formed parts with ultra-high purity were manufactured by selective laser *** tensile and impact mechanical properties of the printed parts under three heat treatment regimes were compared to those without heat *** microstructure,grain orientation and phase composition were characterized by electron-backscatter diffraction,X-ray diffraction and transmission electron *** characterization results reveal that the addition of heat treatment makes the grains enlarge,and after different heat treatments,the average grain size from 1.51μm in the printed state increases to 2.78,3.09 and 2.06μm,*** formed parts are mainly composed of martensite and retained ***,the NiAl and M23C precipitates form,which are the major strengthening phases of PH13-8Mo stainless *** optimal heat treatment process is 925℃×1 h water cooling(WC)+0℃×2 h air cooling(AC)+540℃×4 h *** this heat treatment process,PH13-8Mo formed parts have the optimal comprehensive mechanical properties:the tensile strength,yield strength and impact energy KU2 are 1492 MPa,1432 MPa and 63 J,*** strengthening and toughening via heat treatment are mainly attributed to dislocation strengthening,the formation of NiAl and M23Co precipitates and the change of volume fraction of the retained austenite.

关键词： High-strength stainless steel-Selective laser melting-Heat treatment Microstructure Mechanical property

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Global Solvability for a Predator-Prey Model with Prey-Taxis and Rotational Flux Terms

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Chinese Annals of Mathematics,Series B 2024年第2期45卷 297-318页

作者： Guoqiang REN bin liu School of Mathematics and Statistics Huazhong University of Science and Technology Hubei Key Laboratory of Engineering Modeling and Scientific Computing Huazhong Universityof Science and Technology

In this paper the author investigates the following predator-prey model with prey-taxis and rotational?ux terms■in a bounded domain with smooth *** presents the global existence of generalized solutions to the model... 详细信息

关键词： Predator-prey Prey-taxis Giopal existence Kotational flnux

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Pathological significance of tRNA-derived small RNAs in neurological disorders

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Neural Regeneration Research 2020年第2期15卷 212-221页

作者： Chuan Qin Pei-Pei Xu Xin Zhang Chao Zhang chang-bin liu De-Gang Yang Feng Gao Ming-Liang Yang Liang-Jie Du Jian-Jun Li School of Rehabilitation Medicine Capital Medical UniversityBeijingChina China Rehabilitation Science Institute BeijingChina Center of Neural Injury and Repair Beijing Institute for Brain DisordersBeijingChina Department of Spinal and Neural Functional Reconstruction China Rehabilitation Research CenterBeijingChina Beijing Key Laboratory of Neural Injury and Rehabilitation BeijingChina

Non-coding RNAs(ncRNAs) are a type of RNA that is not translated into proteins. Transfer RNAs(tRNAs), a type of ncRNA, are the second most abundant type of RNA in cells. Recent studies have shown that tRNAs can be cleaved into a heterogeneous population of ncRNAs with lengths of 18–40 nucleotides, known as tRNA-derived small RNAs(tsRNAs). There are two main types of tsRNA, based on their length and the number of cleavage sites that they contain: tRNA-derived fragments and tRNA-derived stress-induced RNAs. These RNA species were first considered to be byproducts of tRNA random cleavage. However, mounting evidence has demonstrated their critical functional roles as regulatory factors in the pathophysiological processes of various diseases, including neurological diseases. However, the underlying mechanisms by which tsRNAs affect specific cellular processes are largely unknown. Therefore, this study comprehensively summarizes the following points:(1) The biogenetics of tsRNA, including their discovery, classification, formation, and the roles of key enzymes.(2) The main biological functions of tsRNA, including its miRNA-like roles in gene expression regulation, protein translation regulation, regulation of various cellular activities, immune mediation, and response to stress.(3) The potential mechanisms of pathophysiological changes in neurological diseases that are regulated by tsRNA, including neurodegeneration and neurotrauma.(4) The identification of the functional diversity of tsRNA may provide valuable information regarding the physiological and pathophysiological mechanisms of neurological disorders, thus providing a new reference for the clinical treatment of neurological diseases. Research into tsRNAs in neurological diseases also has the following challenges: potential function and mechanism studies, how to accurately quantify expression, and the exact relationship between tsRNA and miRNA. These challenges require future research efforts.

关键词： epigenetics molecular biology neurological disorders review sequencing stress tRNA tRNA-derived fragments tRNA-derived small RNAs tRNA-derived stress-induced RNA

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Effect of solute Ce,Mn,and Si on mechanical properties of silicon steel:insights from DFT calculations

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Journal of Iron and Steel Research International 2024年第3期31卷 700-709页

作者： Xiang-jun liu Ji-chun Yang Hui-ping Ren Xiao-bin Jia Ming-yi Zhang chang-qiao Yang School of Materials and Metallurgy Inner Mongolia University of Science and TechnologyBaotou 014010Inner MongoliaChina Key Laboratory of Integrated Exploitation of Bayan Obo Multi-Metal Resource Inner Mongolia University of Science and TechnologyBaotou 014010Inner MongoliaChina Inner Mongolia North Heavy Industries Group Co. Ltd.Baotou 014010Inner MongoliaChina Inner Mongolia Metal Material Research Institute Baotou 014010Inner MongoliaChina

The influence of solute Ce,Mn,and Si on the mechanical properties of silicon steel was investigated by first-principles ***,Mn,and Si can all be solubilized in Fe *** significantly reduces the incompressibility and rigidity of the system but also significantly improves the toughness and *** effect of Mn on mechanical properties of the system is not *** has a significant effect on the improvement in incompressibility and rigidity but a limited effect on the improvement in toughness and *** metallic bond strength of Fe-Ce,Fe-Mn,and Fe-Si doped systems is weaker than that of the pure Fe system,which can be used to explain the reduction in the incompressibility and rigidity of these doped *** relatively high electron cloud density in the doped system may be responsible for the increase in toughness.

关键词： Silicon steel Rare earth First-principles calculation Elastic modulus Electronic structure

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