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Biomedical and Environmental Sciences 2024年第5期37卷 543-548页

作者： XU Dan Han ZHANG Ming CHEN jun Wei Feng chang Zeng liU Yu Han CHU Zhao Yang liU Wen Jing li li MA Shao Hui Institute of Medical Biology Chinese Academy of Medical Sciencesand Peking Union Medical CollegeKunming 650118YunnanChina Yunnan Key Laboratory of Vaccine Research Development on Severe Infectious Disease Kunming 650118YunnanChina School of life Sciences Yunnan UniversityKunming 650504YunnanChina School of Medicine Yunnan UniversityKunming 650504YunnanChina Department of Clinical Laboratory Kunming Maternal and Child Health hospital Kunming 650031YunnanChina

Coxsackievirus(CV)B belongs to the species Enterovirus B,genus Enterovirus of the family *** B(EV-B)includes 63 serotypes:CVB1-6;CVA9;echoviruses E1-7,9,11-21,24-27,and 29-33;EV-B69,EV-B 73-75,EV-B77-88,EV-B 93,EV-B 9... 详细信息

关键词： Coxsackievirus Patients belongs

Enhancement of low-temperature toughness of Fe-Mn-C-Al alloy by rare earth Ce-modified inclusions

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Journal of Iron and Steel Research International 2024年第1期31卷 157-173页

作者： Guang-kai Yang chang-ling Zhuang Yi-zhuang li Chen Hu Shao-bo li College of Materials and Metallurgy Guizhou UniversityGuiyang550025GuizhouChina Department of Mechanical Engineering University of Hong KongHong Kong999077China The State Key Laboratory of Rolling and Automation Northeastern UniversityShenyang110819LiaoningChina State Key Laboratory of Public Big Data Guizhou UniversityGuiyang550025GuizhouChina

Fe-Mn-C-Al alloys have been recognized as promising materials for certain low-temperature applications due to their exceptional mechanical properties and ***,their limited low-temperature toughness restricts their large-scale applications in specific *** influence of trace amounts of rare earth cerium(Ce)on the low-temperature toughness of Fe-18Mn-0.6C-1.8Al alloys was *** addition of Ce effectively alters the inclu-sions in the alloy,transforming large-sized irregular inclusions into fine ellipsoidal rare earth *** leads to a significant reduction in both the proportion and average size of the inclusions,resulting in their effective dispersion throughout the matrix and improved cryogenic *** presence of Ce-containing inclusions within the matrix reduces stress concentration,thereby inhibiting microcrack formation and improving impact absorption ***-cally,the addition of rare earth Ce alters the fracture behavior of the material at room temperature and low temperature,changing from brittle cleavage fracture to a more ductile failure *** impact toughness of the Fe-Mn-C-Al alloy is significantly improved by the addition of 0.0048 wt.%Ce,particularly at-196℃where the impact toughness reaches 103.6 J/cm^(2),representing an impressive improvement of 87.3%.

关键词： Fe-Mn-C-Al alloy Rare earth Low-temperature toughness Inclusion Fracture

Enhanced mechanical property by introducing bimodal grains structures in Cu-Ta alloys fabricated by mechanical alloying

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Journal of Materials Science & Technology 2024年第5期172卷 104-112页

作者： Ningyu li Yongqin chang Mingyang li Yuxiang Chen Xinrui Luo Shichao Pei Fan Yang School of Materials Science and Engineering University of Science and Technology BeijingBeijing 100083China Xi’an Rare Metal Materials Institute Co.Ltd Xi’an 710016China

Dispersion-strengthened copper alloys can achieve ultra-high strength,but usually at the expense of *** this study,a strategy for overcoming strength-ductility tradeoffof Cu alloys is realized through the introduction of bimodal grains ***-Ta alloys with only 0.5 at.%Ta content were successfully prepared by mechanical alloying combined with spark plasm *** samples prepared by one-step and two-step ball milling methods are named as Cu-Ta(Ⅰ)and Cu-Ta(Ⅱ),*** microstructural characterizations revealed that ultra-fine equiaxed grains with uniformly dispersed Ta precipitates were obtained in the Cu-Ta *** strength of 377 MPa for yield strength together with elongation of∼8%was obtained in Cu-Ta(Ⅰ).Bimodal grains structures composed of fine-grain zones and coarse-grain zones were successfully introduced into Cu-Ta(Ⅱ)by a two-step ball milling approach,and both yield strength(463 MPa)and elongation(∼15%)were significantly synergistic *** hardness values of both Cu-Ta(Ⅰ)and Cu-Ta(Ⅱ)were almost kept nearly constant with the increase of annealing time,and the softening temperatures of Cu-Ta(Ⅰ)and Cu-Ta(Ⅱ)are 1018 and 1013℃,reaching 93.9%and 93.5%T m of pure Cu(1083℃),*** reveals that the Cu-0.5 at.%Ta alloys exhibit excellent thermal stability and exceptional softening *** nanoclusters with semi-coherent structures play an essential role in enhancing the strength and microstructural stability of *** structures are beneficial to the activation of back stress strengthening and the initiation and propagation of microcracks,thus obtaining the extraordinary combination of strength and *** study provides a new way to fabricate dispersion-strengthened Cu alloys with high strength,high elongation,excellent thermal stability and softening resistance,which have potential application value in the field of the future fusion reactor.

关键词： Cu-Ta alloy Mechanical alloying Ta precipitates Bimodal structures Mechanical property

Generation and Suppression of Pendant Droplet Oscillation in Electron Beam Directed Energy Deposition

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Engineering 2024年第6期37卷 215-229页

作者： Zhiyue liang Zhenyu liao Haoyu Zhang Zixiang li li Wang Baohua chang Dong Du Department of Mechanical Engineering Tsinghua UniversityBeijing 100084China Key Laboratory for Advanced Materials Processing Technology Ministry of EducationTsinghua UniversityBeijing 100084China

Electron beam–directed energy deposition(EB–DED)has emerged as a promising wire-based metal additive manufacturing ***,the effects of EBs on pendant droplets at wire tips have not yet been *** aim of this study is to enhance the understanding of this action by analyzing the mechanism of droplet *** pendant droplet oscillation phenomenon hinders the stable transfer of droplets to the molten pool and limits the feasibility of manufacturing complex lattice structures by EB–***,another aim of this study is to create an oscillation suppression *** escalating asymmetric amplitude is the main characteristic of droplet *** primary oscillationinducing force is the recoil force generated from the EB-acted local surface of the *** physical mechanism of this force is the rapid increase and uneven distribution of the local surface temperature caused by the partial action of the *** prerequisites for droplet oscillation include vacuum conditions,high power densities,and bypass wire feeding *** proposed EB–dynamic surrounding melting(DSM)method can be applied to conveniently and effectively suppress oscillations,enable the accurate transfer of droplets to the molten pool,and achieve stable processes for preparing the strut elements of lattice *** the temperature and improving the uniformity of its distribution are the mechanisms of oscillation suppression in EB–*** this study,the physical basis for interpreting the mechanism by which EBs act on droplets and the technical basis for using EB–DED to prepare complex lattice structure parts are provided.

关键词： Additive manufacturing Electron beam freeform fabrication In situ monitoring Pendant droplet

Ground-layer Adaptive Optics for the 2.5 m Wide-field and High-resolution Solar Telescope

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Research in Astronomy and Astrophysics 2024年第3期24卷 224-236页

作者： Ying Yang Lan-Qiang Zhang Nan-Fei Yan Jin-Sheng Yang Zhen li Teng-Fei Song Xue-jun Rao chang-Hui Rao Key Laboratory on Adaptive Optics Chinese Academy of SciencesChengdu 610209China Institute of Optics and Electronics Chinese Academy of SciencesChengdu 610209China School of Electronic Electrical and Communication Engineering of the University of Chinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China School of Astronomy and Space Science Nanjing UniversityNanjing 210023China Key Laboratory of Modern A&A Ministry of EducationNanjing 210023China Yunnan Observatories Chinese Academy of SciencesKunming 650216.China

The 2.5 m wide-field and high-resolution solar telescope(WeHoST)is currently under developing for solar *** aims to achieve high-resolution observations over a super-wide field of view(FOV)of5′×5′,and a desired resolution of 0.3″.To meet the scientific requirements of WeHoST,the ground-layer adaptive optics(GLAO)with a specially designed wave front sensing system is as the primary *** introduce the GLAO configuration,particularly the wave front sensing *** analytic method,we simulate the performance of both classical AO and GLAO systems,optimize the wave front sensing system,and evaluate GLAO performance in terms of PSF uniformity and correction improvement across whole *** results indicate that,the classical AO will achieve diffraction-limited resolution;the suggested GLAO configuration will uniformly improve the seeing across the full 5′×5′FOV,reducing the FWHM across the axis FOV to less than0.3″(λ≥705 nm,r0≥11 cm),which is more than two times *** specially designed wave front sensor schedule offers new potential for WeHoST’s GLAO,particularly the multi-FOV GLAO and the flexibility to select the detected *** capabilities will significantly enhance the scientific output of the telescope.

关键词： instrumentation adaptive optics-instrumentation detectors-instrumentation high angular resolution-methods numerical-telescopes-Sun activity

An online value iteration method for linear-quadratic mean field social control with unknown dynamics

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Science China(Information Sciences) 2024年第4期67卷 38-39页

作者： Bing-chang WANG Shumei li Ying CAO School of Control Science and Engineering Shandong University

Mean field(MF) models have been widely applied to economics, control theory, and other fields. Its prominent feature is that the individual influence on the overall population is negligible and the impact of the entire system to the single agent is significant and cannot be ignored. As a classical problem in control theory, linear quadratic(LQ) control for MF models has been widely investigated(e.g., [1, 2]).

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Protein lipidation in health and disease:molecular basis,physiological function and pathological implication

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Signal Transduction and Targeted Therapy 2024年第4期9卷 1423-1465页

作者： Yuan Yuan Peiyuan li jianghui li Qiu Zhao Ying chang Xingxing He Department of Gastroenterology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina Department of Gastroenterology Zhongnan Hospital of Wuhan UniversityWuhanChina Hubei Clinical Center and Key Laboratory of Intestinal and Colorectal Diseases WuhanChina

Posttranslational modifications increase the complexity and functional diversity of proteins in response to complex external stimuli and internal *** these,protein lipidations which refer to lipid attachment to proteins are prominent,which primarily encompassing five types including S-palmitoylation,N-myristoylation,S-prenylation,glycosylphosphatidylinositol(GPl)anchor and *** attachment to proteins plays an essential role in the regulation of protein trafficking,localisation,stability,conformation,interactions and signal transduction by enhancing *** evidence from genetic,structural,and biomedical studies has consistently shown that protein lipidation is pivotal in the regulation of broad physiological functions and is inextricably linked to a variety of *** of dedicated research have driven the development of a wide range of drugs targeting protein lipidation,and several agents have been developed and tested in preclinical and clinical studies,some of which,such as asciminib and lonafarnib are FDA-approved for therapeutic use,indicating that targeting protein lipidations represents a promising therapeutic ***,we comprehensively review the known regulatory enzymes and catalytic mechanisms of various protein lipidation types,outline the impact of protein lipidations on physiology and disease,and highlight potential therapeutic targets and clinical research progress,aiming to provide a comprehensive reference for future protein lipidation research.

关键词： lipid ation primarily

Enhanced photothermal dehydration of methanol over W_(18)O_(49)/Au/SAPO-34 catalysts with broadened light absorption

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Rare Metals 2024年第3期43卷 1139-1152页

作者： Ya-Qin Tang Meng-Xia Yan chang-Qian Lu Shao-Yuan li Kui-Xian Wei Tao Qu Wen-HuiMa Yong-Nian Dai Kong-Zhai li Da-jun Luo Xue-liang Zhang Yi-Ke liu Faculty of Metallurgical and Energy Engineering Kunming University of Science and TechnologyKunming650093China School of Materials and Energy Engineering Guizhou Institute of TechnologyGuiyang550003China

Methanol-to-olefins(MTO)process is one of the most critical pathways to produce low carbon ***,the reaction is driven by thermal catalysis,which inevitably needs to consume large amounts of fossil *** a new technique to substitute for the fuel burning is urgent for MTO process to improve the industry prospects and ***,we report a novel W_(18)O_(49)/Au/SAPO-34(W/Au/S),a multifunctional photothermal catalyst for the MTO reaction.A high methanol conversion was achieved under xenonum(Xe)lamp irradiation,yielding methyl ether(ME)and ethylene as the main *** optimized W/Au/S catalysts showed ethylene yield as high as 250μmol in 60 min,which was 2.5 times higher than that of Au/*** physiochemical characterization revealed that the SAPO-34 molecular sieves were surrounded by Au and W_(18)O_(49)nanoparticles,which exhibited a strong localized surface plasmon resonance excitation around 540 nm and light absorption beyond 500 *** multifunctional catalysts showed a strong photothermal effect,arising from the broadened light absorption of Au and W_(18)O_(49)nanoparticles,leading to a temperature as high as 250℃on the surface of the *** study showed that the superior ethylene selectivity of W/Au/S catalysts was attributed to the moderating acidic sites of W_(18)O_(49)for methanol dehydration to *** research may provide new insight for designing heterostructures to improve photo-to-chemical conversion performance and is expected to accelerate progress toward the excellent multifunctional photothermal catalysts with broad light absorption for methanol activation and C-C bond formation.

关键词： Methanol conversion Ethylene Photothermal catalysis W_(18)O_(49) BrΦnsted-acid

Microstructure Evolution and Nanomechanical Behavior of Micro-Area in Molten Pool of Selective Laser Melting(CoCrNi)_(82)Al_(9)Ti_(9)High-Entropy Alloy

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Acta Metallurgica Sinica(English Letters) 2024年第6期37卷 1019-1033页

作者： Hong-Wei Zhang li-Wei Lan Zhe-Yu Yang chang-Chun li Wen-Xian Wang College of Materials Science and Engineering Taiyuan University of TechnologyTaiyuan030024China Ministry of Education Key Laboratory of Interface Science and Engineering in Advanced MaterialsTaiyuan University of TechnologyTaiyuan030024China Shanxi-Zhejiang University New Materials and Chemical Research Institute Taiyuan030032China

In this work,the phase evolution mechanism and nanomechanical properties of(CoCrNi))(82)Al_(9)Ti_(9)high-entropy alloy(HEA)prepared by selective laser melting(SLM)in the molten pool were *** HEA contains multiple primary elements and undergoes high-temperature gradient and rapid cooling during *** leads to significant inhomogeneity of nano-scale microstructure characteristics and instability of *** optimizing process parameters,the microstructure evolution at the optimal parameter volume energy density of 440 J/mm^(3)was studied.A phase transition from BCC to FCC occurred in the melt *** the micro-area of the melt pool results in a temperature rise and the combustion-induced loss of Al ***,the Ni element content increases significantly outside the melt *** process enhances the phase stability of FCC and facilitates phase ***,rapid cooling leads to the formation of distinctive ultrafine equiaxial crystals inside the melt pool,accompanied by the generation of intracrystalline needle-like nano-scale *** the melt pool,the accumulation of energy results in the formation of coarse ***,the nano-hardness inside the molten pool is remarkably high at 11.79 GPa,while the outside the molten pool is reduced to 9.58 *** the fracture toughness outside the melt pool also *** with inside the melt pool,the residual stress outside the melt pool changed from compressive to tensile stress and decreased from 603.28 to 322.84 MPa.

关键词： High-entropy alloys Selective laser melting Microstructure evolution Nanoindentation

Recent progress on the synthesis of defective UiO-66 for thermal catalysis

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Nano Research 2024年第10期17卷 8653-8670页

作者： Qing Feng Caoyu Yang lin chang Guodong li Zhiyong Tang CAS Key Laboratory of Nanosystem and Hierarchical Fabrication CAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190China School of Nanoscience and Engineering University of Chinese Academy of SciencesBeijing 100049China

Zirconium terephthalate UiO-66 has aroused great interest in catalysis since it exhibits significant flexibility and compatibility for accommodating a high number of defects as well as exceptional thermal and chemical *** now,many works have focused on the modulations of the Zr6-oxo clusters in UiO-66 in terms of diverse synthesis,advanced characterizations,and their catalytic *** achieve high catalytic efficiency,it is still highly desired for rationally constructing and modulating the Zr6-oxo clusters with exposed catalytic sites and diverse microenvironments for advanced *** this review,we provide a comprehensive summary of recent progress on the synthesis of defective UiO-66,qualitative and quantitative characterizations,as well as a logical overview of heterogeneous catalytic applications over the past few ***,the outlooks for the research paradigm of defective UiO-66 are discussed.

关键词： defective UiO-66 de novo synthesis post-synthetic treatment characterization thermal catalysis