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Organic X-Ray Image Sensors Using a Medium Bandgap Polymer Donor with Low Dark Current

Energy & Environmental Materials 2024年第6期7卷 230-237页

作者： Jong-Woon Ha Seung Hun Eom Bo Kyung cha Seyeong Song Hyeong Ju Eun Jong H.Kim Jong Mok Park BongSoo Kim Byoungwook Park Seo-Jin Ko Sung Cheol Yoon changjin Lee In Hwan Jung Do-Hoon Hwang Department of Chemistry Chemistry Institute for Functional MaterialsPusan National UniversityBusan 46241Korea Division of Advanced Energy Materials Research Center Korea Research Institute of Chemical Technology(KRICT)Daejeon 34114Korea Electro-Medical Device Research Center Korea Electrotechnology Research Institute(KERI)Ansan 15588Korea Graduate School of Carbon Neutrality School of Energy and Chemical EngineeringUlsan National Institute of Science and Technology(UNIST)Ulsan 44919Korea Department of Molecular Science and Technology Ajou UniversitySuwon 16449Korea Research Center for Advanced Specialty Chemicals Korea Research Institute of Chemical TechnologyUlsan 44412Korea Department of Chemistry Ulsan National Institute of Science and Technology(UNIST)Ulsan 44919Korea Department of Organic and Nano Engineering Human-Tech Convergence ProgramHanyang University222 Wangsimni-roSeongdong-guSeoul 04763Korea

The development of portable X-ray detectors is necessary for diagnosing fractures in unconscious patients in emergency ***,this is quite challenging because of the heavy weight of the scintillator and silicon *** weight and thickness of X-ray detectors can be reduced by replacing the silicon layer with an organic *** study presents a novel bithienopyrroledione-based polymer donor that exhibits excellent photodetection properties even in a thick photoactive layer(~700 nm),owing to the symmetric backbone and highly soluble molecular structure of *** ability of bithienopyrroledione-based polymer donor to strongly suppress the dark current density(Jd~10−10 A cm^(−2))at a negative bias(−2.0 V)while maintaining high responsivity(R=0.29 A W−1)even at a thickness of 700 nm results in a maximum shot-noise-limited specific detectivity of D_(sh)^(*)=2.18×10^(13)Jones in the organic *** organic photodetectors are developed by slot-die coating for use in X-ray detectors,which exhibit D_(sh)^(*)=2.73×10^(12)Jones with clear rising(0.26 s)and falling(0.29 s)response times upon X-ray *** reliability is also proven by linear response of the X-ray detector,and the X-ray detection limit is 3 mA.

关键词： low dark current low detection limit organic photodetector printable X-ray

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From liver to hormones:The endocrine consequences of cirrhosis

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World Journal of Gastroenterology 2024年第9期30卷 1073-1095页

作者： Juan Eduardo Quiroz-Aldave Elman Rolando Gamarra-Osorio María del Carmen Durand-Vásquez Luciana del Pilar Rafael-Robles Jhean Gabriel Gonzáles-Yovera María Alejandra Quispe-Flores Luis Alberto Concepción-Urteaga Alejandro Román-González José Paz-Ibarra Marcio José Concepción-Zavaleta Non-communicable Diseases Endocrinology Research LineHospital de Apoyo ChepénChepén 13871Peru Department of Endocrinology Hospital Víctor Lazarte EchegarayTrujillo 13006Peru Department of Endocrinology Clínica Javier PradoLima 15046Peru Department of Gastroenterology Hospital Nacional Guillermo Almenara IrigoyénLima 15018Peru Department of Endocrinology Hospital de Emergencias GrauLima 15001Peru Internal Medicine Hospital Regional Docente de TrujilloTrujillo 13011Peru Department of Endocrinology Hospital Universitario de San Vicente FundaciónMedellin 050010Colombia Internal Medicine Universidad de AntioquiaMedellín 050010Colombia School of Medicine Universidad Nacional Mayor de San MarcosLima 15081Peru Department of Endocrinology Hospital Nacional Edgardo Rebagliati MartinsLima 15072Peru Carrera de Medicina Humana Universidad Científica del SurLima 15067Peru

Hepatocrinology explores the intricate relationship between liver function and the endocrine *** liver diseases such as liver cirrhosis can cause endocrine disorders due to toxin accumulation and protein synthesis *** its importance,assessing endocrine issues in cirrhotic patients is frequently *** article provides a comprehensive review of the epidemiology,pathophysiology,diagnosis,and treatment of endocrine disturbances in liver *** review was conducted using the PubMed/Medline,EMBASE,and Scielo databases,encompassing 172 *** cirrhosis is associated with endocrine disturbances,including diabetes,hypoglycemia,sarcopenia,thyroid dysfunction,hypogonadotropic hypogonadism,bone disease,adrenal insufficiency,growth hormone dysfunction,and secondary *** optimal tools for diagnosing diabetes and detecting hypoglycemia are the oral glucose tolerance test and continuous glucose monitoring system,*** can be assessed through imaging and functional tests,while other endocrine disorders are evaluated using hormonal assays and imaging *** options include metformin,glucagon-like peptide-1 analogs,sodium-glucose co-transporter-2 inhibitors,and insulin,which are effective and safe for diabetes *** standards are followed for managing hypoglycemia,and hormone replacement therapy is often necessary for other endocrine *** transplantation can address some of these problems.

关键词： Diabetes mellitus Hypoglycemia Thyroid diseases Hypogonadism Metabolic bone diseases Liver cirrhosis

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Effect of Luhong formula on the cardiac rehabilitation of patients with chronic heart failure

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World Journal of Clinical Cases 2024年第17期12卷 3027-3034页

作者： Ji-Jie Xu Jian Dai Qi-Hai Xie Pei-chao Du cha Li Hua Zhou Department of Cardiology&Cardiovascular Research Institute Shanghai Baoshan District Hospital of Integrated Traditional Chinese and Western MedicineShanghai 201999China

BACKGROUND Current treatments for chronic heart failure(CHF)are therapeutically *** optimization of treatments for this disease needs to be explored and *** To analyze the effect of using Luhong Formula in the cardiac rehabilitation of patients with CHF and its influence on cardiopulmonary function(CPF)and *** In total,160 patients with CHF admitted between June 2022 and June 2023 were selected,including 75 receiving perindopril(control group)and 85 receiving Luhong Formula(research group).We conducted comparative analyses on the curative effects of traditional Chinese medicine(TCM)syndromes and cardiac function,CPF[oxygen consumption at the anaerobic threshold(VO2 AT)and at peak exercise(peak VO2)],echocardiographic indexes[left atrial volume index(LAVI),left ventricular muscle mass index(LVMI),left ventricular ejection fraction(LVEF)],and prognosis[major adverse cardiovascular events(MACEs)at 6 months follow-up].RESULTS The research group showed markedly higher curative effects of TCM syndromes and cardiac function than the control *** addition,post-treatment VO2 AT,peak VO2,LVMI and LVEF in the research group were significantly higher,whereas LAVI was significantly lower,than those of the control ***,fewer patients in the research group developed MACEs at the 6-month *** Luhong Formula is more therapeutically effective than perindopril for the cardiac rehabilitation of patients with CHF,specifically in enhancing CPF and prognosis.

关键词： Luhong formula Chronic heart failure Cardiopulmonary function Cardiac rehabilitation Prognosis

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血浆胎盘源性细胞外囊泡异常增高预警重度子痫前期患者不良妊娠结局

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中华检验医学杂志 2024年第5期47卷 561-569页

作者：陈媛媛门剑龙韩姹天津医科大学总医院妇产科天津市女性生殖健康与优生重点实验室天津300052 天津医科大学总医院精准医学中心天津300052

目的:评价血浆中胎盘源性细胞外囊泡(pcEV)及其清除蛋白乳凝集素(Lactadherin)预测重度子痫前期(sPE)患者妊娠不良结局的诊断性能。方法:回顾性病例对照研究。收集2018年1月31日至2019年1月31日产检并分娩妊娠27~37周诊断为sPE的患者60... 详细信息

目的:评价血浆中胎盘源性细胞外囊泡(pcEV)及其清除蛋白乳凝集素(Lactadherin)预测重度子痫前期(sPE)患者妊娠不良结局的诊断性能。方法:回顾性病例对照研究。收集2018年1月31日至2019年1月31日产检并分娩妊娠27~37周诊断为sPE的患者60例,年龄32(29,36)岁,根据发生终点事件(胎儿窘迫和/或胎儿生长受限)情况,将sPE患者进一步分为事件组34例,无事件组26例。同孕周健康孕妇33例为孕妇对照组,年龄31(29,36)岁。非孕期健康女性25例为健康对照组,年龄26(25,38)岁。采用流式细胞仪检测胎盘碱性磷酸酶抗体阳性者为pcEV,同时膜表面表达磷脂酰丝氨酸者,即膜联蛋白V(AV)阳性为AV+pcEV。ELISA法检测Lactadherin水平。用Logistic回归做多元相关性分析,用受试者工作特征(ROC)曲线评价pcEV和Lactadherin预测妊娠不良结局的性能。用Kaplan-Meier曲线进行生存分析。用Cox比例风险回归模型计算风险比(HR)。结果:sPE组血浆AV+pcEV水平为8260(4991,16751)个/μl,高于健康孕妇组的1088(784,1871)个/μl和健康对照组的206(116,256)个/μl(H=94.490,P<0.05)。事件组sPE患者血浆AV+pcEV水平为11225(7496,20599)个/μl,高于无事件组的5199(2914,8347)个/μl(U=178,P<0.05)。sPE组血浆Lactadherin为2635(1876,3137)pg/ml,高于健康孕妇组的1597(1287,1818)pg/ml和健康对照组的1123(749,1405)pg/ml(H=54.307,P<0.05)。ROC曲线显示,AV+pcEV预测sPE患者77 d内发生胎儿窘迫和/或胎儿生长受限事件的临界值为6524个/μl时,曲线下面积(AUC)为0.799(95%CI 0.680~0.917)。Lactadherin预测的临界值为2336.5 pg/ml时,AUC为0.702(95%CI 0.564~0.841)。Logistic回归分析显示,sPE患者AV+pcEV水平与患者24 h尿蛋白定量(OR=9.288,95%CI 1.993~43.293)以及患者是否需要联合用药降压治疗(OR=18.690,95%CI 1.919~182.077)有相关性(P<0.05)。生存分析显示AV+pcEV水平高于临界值的sPE患者在77 d内的发生胎儿窘迫和/或胎儿生长受限事件的累积概率增高(Log-rankχ^(2)=21.430,P<0.05)。Cox比例回归模型显示AV+pcEV水平可独立识别胎儿窘迫和/或胎儿生长受限事件(HR=7.983,P<0.05)。结论:妊娠晚期孕妇血浆中pcEV水平变化与PE病情发展相关,高浓度pcEV提示胎儿窘迫、胎儿生长受限风险增加,可作为预警不良妊娠结局的有效标志物。

关键词：先兆子痫胎盘源性细胞外囊泡乳凝集素流式细胞技术妊娠结局

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青少年非自杀性自伤的识别和干预

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中国儿童保健杂志 2024年第7期32卷 697-699页

作者：查彩慧欧婉杏广州医科大学附属妇女儿童医疗中心精神心理科

非自杀性自伤多见于青少年，其表现形式多样，但不以自杀为目的，目前缺乏有效的应对措施。本文针对自伤行为的方式、影响因素、患者的心理需求，以及干预的策略等问题进行分析和总结。

关键词：非自杀性自伤青少年自我伤害

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Improving the operational stability of perovskite solar cells with cesium-doped graphene oxide interlayer

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Journal of Energy Chemistry 2024年第9期96卷 483-490页

作者： Masaud Almalki Katerina Anagnostou Konstantinos Rogdakis Felix T.Eickemeyer Mostafa Othman Minas M.Stylianakis Dimitris Tsikritzis Anwar Q.Alanazi Nikolaos Tzoganakis Lukas Pfeifer Rita Therisod Xiaoliang Mo Christian M.Wolff Aïcha Hessler-Wyser Shaik M.Zakeeruddin Hong Zhang Emmanuel Kymakis Michael Grätzel Laboratory of Photonics and Interfaces École Polytechnique Fédérale de Lausanne(EPFL)Lausanne 1015Switzerland Department of Electrical and Computer Engineering Hellenic Mediterranean UniversityHeraklionCrete 71410Greece Institute of Electrical and Microengineering(IEM)Photovoltaics and Thin-Film Electronics Laboratory(PV-Lab) École Polytechnique Fédérale de Lausanne(EPFL)Neuchâtel 2000Switzerland Department of Nursing Faculty of Health SciencesHellenic Mediterranean UniversityCrete 71410Greece Centre Interdisciplinaire de Microscopie Electronique École Polytechnique Fédérale de Lausanne(EPFL)Lausanne 1015Switzerland Future Energy Technology Institute King Abdulaziz City for Science and Technology(KACST)P.O.Box 6086Riyadh 11442Saudi Arabia State Key Laboratory of Photovoltaic Science and Technology Shanghai Frontiers Science Research Base of Intelligent Optoelectronics and PerceptionInstitute of OptoelectronicsDepartment of Materials ScienceFudan UniversityShanghai 200433China

Perovskite solar cells(PSCs)have made great advances in terms of power conversion efficiency(PCE),yet their subpar stability continues to hinder their *** interface between the perovskite layer and the charge-carrier transporting layers plays a crucial role in undermining the stability of *** this work,we propose a strategy to stabilize high-performance PSCs with PCE over 23%by introducing a cesium-doped graphene oxide(GO-Cs)as an interlayer between the perovskite and hole-transporting *** GO-Cs treated PSCs exhibit excellent operational stability with a projected T80(the time where the device PCE reduces to 80%of its initial value)of 2143 h of operation at the maximum powering point under one sun illumination.

关键词： Perovskite solar cells Doped graphene oxide Graphene related material Long-term operational stability

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流体喷管对脉冲爆震发动机推进性能的影响

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航空动力学报 2024年第2期39卷 47-56页

作者：门凯邱华严宇熊姹陈山山西北工业大学动力与能源学院西安710129 西安航天动力研究所热过程重点实验室西安710100

为了进一步提高脉冲爆震发动机(PDE)的推进性能,对PDE使用流体喷管模型进行了多循环数值模拟研究,并提出了主次流错相位喷注方案。结果表明:主次流错相位喷注方案不仅可以调节主流和二次流的有效流通面积,改善喷管的非设计点状态,而且... 详细信息

为了进一步提高脉冲爆震发动机(PDE)的推进性能,对PDE使用流体喷管模型进行了多循环数值模拟研究,并提出了主次流错相位喷注方案。结果表明:主次流错相位喷注方案不仅可以调节主流和二次流的有效流通面积,改善喷管的非设计点状态,而且可以提高爆震室内可燃气最终充填压力,增强爆震燃烧强度;在主次流错相位喷注方案下,喷管主流进口瞬时气流总压相对喷管设计点的离散程度明显下降,有效改善了喷管的非设计点状态;最佳的主次流相位差为反传压缩波恰好传播至爆震室头部这一工况,最佳的二次流喷注位置为喷管喉部;相比基准喷管的最大比冲性能,PDE使用流体喷管可以产生5.64%的比冲增益。

关键词：脉冲爆震发动机喷管二次流内流分析推进性能

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1930年代梁漱溟与全国乡村工作讨论会

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历史教学问题 2024年第4期 51-58,75,195页

作者：察应坤山东大学儒学高等研究院 250100

20世纪初,全国农业农村蔓延的衰落情势引发了知识界团体对于救济农村的广泛社会行动。其后,全国各地域乡村工作者一致有意成立一个全国乡村服务人员的联合组织。1933年、1934年、1935年连续三年,在梁漱溟、晏阳初、黄炎培、章元善等人... 详细信息

20世纪初,全国农业农村蔓延的衰落情势引发了知识界团体对于救济农村的广泛社会行动。其后,全国各地域乡村工作者一致有意成立一个全国乡村服务人员的联合组织。1933年、1934年、1935年连续三年,在梁漱溟、晏阳初、黄炎培、章元善等人努力操持下,先后召开了三次全国乡村工作会,参会团体和参会代表覆盖全国南北各地,中央党部,中央政府农业、教育、金融等部,地方政府、媒体及外国人士多有参加,影响声势浩大。然而,在当时形势下,全国乡村工作讨论会却始终维系着一种松散的联合体的状态,没有在官方注册为一个合法社团。各个乡建团体基于不同的政治环境立场出发对中国问题的认识不同,在乡村改进的解决路径、追求目标、工作侧重点、运营机制等方面有着诸多分歧,很难对整体的乡建运动有一个整体的把握和方向性的推动。乡建工作的“孤岛”现象依然没有改变。

关键词：乡村建设乡村改进梁漱溟晏阳初

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Hemophagocytic lymphohistiocytosis triggered by relapsing polychondritis:A case report

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World Journal of Orthopedics 2024年第8期15卷 813-819页

作者： Mi-Ran Han Jeong-Hwan Hwang Seungah cha So-Yeon Jeon Kyu Yun Jang Namsu Kim chang-Hoon Lee Department of Internal Medicine Jeonbuk National University Medical SchoolJeonju 54907South Korea Department of Pathology Jeonbuk National University Medical SchoolJeonju 54907South Korea Department of Laboratory Medicine Jeonbuk National University Medical SchoolJeonju 54907South Korea

BACKGROUND Hemophagocytic lymphohistiocytosis(HLH)is a rare,life-threatening disorder caused by abnormal histiocytes and T cell *** adults,it is predominantly associated with infections,cancers,and autoimmune *** polychondritis(RP),another rare disease,is diagnosed based on symptoms without specific tests,featuring cartilage inflammation characterized by swelling,redness,and pain,rarely inducing *** SUMMARY A 74-year-old woman visited the emergency room with a fever of 38.6℃.Blood tests,cultures,and imaging were performed to evaluate *** showed increased fluorescent antinuclear antibody levels and mild cytopenia,with no other specific *** revealed lymph node enlargement was observed;however,biopsy results were *** re-evaluation of the physical exam,inflammatory signs suggestive of RP were observed in the ears and nose,prompting a tissue biopsy for ***,persistent fever accompanied by cytopenia prompted a bone marrow examination,revealing hemophagocytic *** finding no significant results in blood culture,viral markers,and tissue examination of enlarged lymph nodes,HLH was diagnosed by *** involved methylprednisolone followed by *** two months,bone marrow examination confirmed resolution of hemophagocytosis,with normalization of hyperferritinemia and *** Thorough physical examination enabled diagnosis and treatment of HLH trig gered by RP in patients presenting with fever of unknown origin.

关键词： Hemophagocytic lymphohistiocytosis Relapsing polychondritis Autoimmune disease Fever of unknown origin Steroid Case report

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化工防腐中高分子化工材料的运用分析

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化工设计通讯 2024年第8期50卷 29-31页

作者：查丽宁夏工业设计院有限责任公司宁夏银川750001

在化工行业的产品生产过程中,化工机械设备常因材料与使用环境的影响而出现化学腐蚀、电化学腐蚀、生物腐蚀等腐蚀情况,降低整体生产效率。为进一步提高化工防腐效果,保障行业生产,通过深入分析目前化工机械设备常见的腐蚀类型,并阐述... 详细信息

在化工行业的产品生产过程中,化工机械设备常因材料与使用环境的影响而出现化学腐蚀、电化学腐蚀、生物腐蚀等腐蚀情况,降低整体生产效率。为进一步提高化工防腐效果,保障行业生产,通过深入分析目前化工机械设备常见的腐蚀类型,并阐述化工防腐中常用的化工材料。最后,从涂层保护、结构加固、密封和衬里等方面,总结了化工防腐中高分子化工材料的具体应用路径,以再次验证其在化工防腐中的应用效果,提高化工产业机械防腐性能。

关键词：化工防腐高分子化工材料化学腐蚀

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