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Artificial intelligence in gastroenterology:where are we heading?

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Frontiers of Medicine 2020年第4期14卷 511-517页

作者： Joseph JY Sung Nicholas ch Poon Institute of Digestive Disease Faculty of MedicineThe Chinese University of Hong KongHong KongChina Big Data Decision Analytic Cancer The Chinese University of Hong KongHong KongChina

Artificial intelligence(AI)is coming to medicine in a big *** making diagnosis in various medical conditions,following the latest advancements in scientific literature,suggesting appropriate therapies,to predicting prognosis and outcome of diseases and conditions,AI is offering unprecedented possibilities to improve care for *** is a field that AI can make a significant *** is partly because the diagnosis of gastrointestinal conditions relies a lot on image-based investigations and procedures(endoscopy and radiology).AI-assisted image analysis can make accurate assessment and provide more information than conventional *** integration of genomic,epigenetic,and metagenomic data may offer new classifications of gastrointestinal cancers and suggest optimal personalized *** managing relapsing and remitting diseases such as inflammatory bowel disease,irritable bowel syndrome,and peptic ulcer bleeding,convoluted neural network may formulate models to predict disease outcome,enhancing treatment *** and surgical robots can also assist surgeons in conducting gastrointestinal *** the advancement and new opportunities are exciting,the responsibility and liability issues of AI-assisted diagnosis and management need much deliberations.

关键词： artificial intelligence endoscopy robotics gastrointestinal diseases

De Broglie–Bohm Interpretation of Canonical Quantum Cosmology Implies Early Stages of the Universe Dominated by Radiation

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Communications in Theoretical Physics 2013年第12期60卷 691-694页

作者： ch’ng Han Siong Shahidan Radiman Sch.ol of Applied Physics Faculty of Science and Technology Universiti Kebangsaan Malaysia

The Einstein＇s genera/relativity is formulated in the Hamiltonian form for a spatia/ly Bat, isotropic and homogeneous universe. Subsequently, we perform the canonical quantization procedure to the Hamiltonian to obtain the Wheeler-DeWitt equation. Solving the Wheeler-DeWitt equation and employing the de Broglie-Bohm interpretation to the wave function of the universe, we obtain a new version of spatia/ly fiat Friedmann equation for the early universe where the scale factor of the universe is taken to be sufilcientlv small.

关键词： de Broglie-Bohm interpretation canonical quantum cosmology Friedmann equation Wheeler-DeWitt equation

Cell Death Mechanisms Induced by Cytotoxic Lymphocytes

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Cellular & Molecular Immunology 2009年第1期6卷 15-25页

作者： chávez-Galán L Arenas-Del Angel MC Zenteno E chávez R Lascurain R Departamento de Bioquímica Instituto Nacional de Enfermedades Respiratorias "Ismael Cosío Villegas" Departamento de Bioquímica Facultad de MedicinaUniversidad Nacional Autónoma de México

one of the functions of the immune system is to recognize and destroy abnormal or infected cells to maintain homeostasis. This is accomplished by cytotoxic lymphocytes. Cytotoxicity is a highly organized multifactor process. Here, we reviewed the apoptosis pathways induced by the two main cytotoxic lymphocyte subsets, natural killer （NK） cells and CD8^＋T cells. In base to recent experimental evidence, we reviewed NK receptors involved in recognition of target-cell, as well as lytic molecules such as perforin, granzymes-A and -B, and granulysin. In addition, we reviewed the Fas-FasL intercellular linkage mediated pathway, and briefly the cross-linking of tumor necrosis factor （TNF） and TNF receptor pathway. We discussed three models of possible molecular interaction between lytic molecules from effector cytotoxic cells and target-cell membrane to induction of apoptosis. Cellular ＆ Molecular Immunology.

关键词： apoptosis cytotoxic cell granule-dependent exocytosis FasL TNF

Adaptive Signal Enhancement Unit for EEG Analysis in Remote Patient Care Monitoring Systems

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Computers, Materials & Continua 2021年第5期67卷 1801-1817页

作者： ch.Srinivas K.chandrabhushana Rao Department of Electronics and Communication Engineering J.N.T.UniversityKakinada533003India Department of Electronics and Communication Engineering JNTUK-UCEVVizianagaram535003India

In this paper we propose an efcient process of physiological artifact elimination methodology from brain waves(BW),which are also commonly known as electroencephalogram(EEG)*** a clinical environment during the acquisition of BW several artifacts contaminates the actual BW *** leads to inaccurate and ambiguous *** the statistical nature of the EEG signal is more non-stationery,adaptive ltering is the more promising method for the process of artifact *** clinical conditions,the conventional adaptive techniques require many numbers of computational operations and leads to data samples overlapping and instability of the algorithm *** causes delay in diagnosis and decision *** overcome this problem in our work we propose to set a threshold value to diminish the problem of round off *** resultant adaptive algorithm based on this strategy is Non-linear Least mean square(NL2MS)***,to improve this algorithm in terms of ltering capability we perform data normalization,using this algorithm several hybrid versions are developed to improve ltering and reduce computational *** the method,a new signal enhancement unit(SEU)is realized and performance of various hybrid versions of algorithms examined using real EEG signals recorded from the *** ability of the proposed schemes is measured in terms of convergence,enhancement and multiplications *** various SEUs,the MCN2L 2MS algorithm achieves 14.6734,12.8732,10.9257,15.7790 dB during the artifact removal of RA,EMG,CSA and EBA components with only two ***,this algorithm seems to be better candidate for artifact elimination.

关键词： Adaptive algorithms artifacts brain waves clipped algorithms signal enhancement unit wireless EEG monitoring

The Transient Time-Resolved Absorption Spectra of 1-Naphthylacetic Acid

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chinese chemical Letters 2000年第3期11卷 261-262页

作者： Li, W Tung, ch Ye, JP chinese Acad Sci Inst Photog Chem Beijing 100101 Peoples R China

The transient absorption spectra of 1-naphthylacetic acid in tetrahydrofuran have been obtained by laser flash photolysis technique. The transient species bands are at 509, 535 and 553 nm. These peak intensities incre... 详细信息

关键词： transient spectra laser chemistry 1-naphthylacetic acid

Synthesis and Spectrophotometric Studies of 2-(5-Carboxy-1,3,4-triazolylazo)-5-diethylamino Aniline

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chinese chemical Letters 2000年第10期11卷 861-862页

作者： Pan, FY Ge, ch Liang, HD Taizhou Teachers Coll Dept Chem Zhejiang 317000 Peoples R China

In this paper, 2-(5-carboxy-1,3,4-triazolylazo)-5-diethylamino aniline(CTZAN) was prepared the protonation behaviour of this reagent is reported. Its structure was identified.

关键词： synthesis triazolylazo spectrophotometry protonation behaviour

Photoisomerization of norbornadiene group in a rigid bich.omophoric compound initiated by remote keto ch.omophore: long-distance through-bond triplet energy transfer

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chinese Journal of chemistry 1996年第4期14卷 377-380页

作者： Tung, ch Zhang, LP Li, Y chINESE ACAD SCI INST PHOTOG CHEMBEIJING 100101PEOPLES R CHINA

A diad compound 3 beta(bicyclo[2,2,1]hepta-2,5-diene-2-methylcarboxylate-3-carboxy)-androst-5-en-17-one (NBD-S-oNE) was synthesized and its photochemistry was examined. Irradiation of NBD-S-oNE in acetonitrile at lambda > 300 nm selectively excited the keto ch.omophore. After intersystem crossing, the triplet energy of the keto group was transferred to the NBD group with 18.6% efficiency via a through-bond mechanism, resulting in the isomerization of the latter group to the quadricyclane group.

关键词： norbornadiene photoisomerization through-bond triplet energy transfer

Development of open-porosity magnesium foam produced by investment casting

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Journal of Magnesium and Alloys 2022年第7期10卷 1941-1956页

作者： Honorata Kapłon Carsten Blawert Jacek ch˛ecmanowski Krzysztof Naplocha Faculty of Mechanical Engineering Wrocław University of Science and TechnologyUl.Smoluchowskiego 25Wrocław 50-370Poland Institute of Surface Science Helmholtz-Zentrum GeesthachtMax-Planck-Straβe 1Geesthacht21502Germany Faculty of chemistry Wrocław University of Science and TechnologyWybrze˙ze Stanisława Wyspia´nskiego 27Wrocław50-370Poland

High-porosity,open-cell AZ91 magnesium alloy foams of two pore sizes were fabricated by means of investment casting tech.ology,using PUR foam *** casting variables such as pressure,mould temperature and metal pouring temperature were thoroughly investigated to define the most optimal casting *** mechanical properties of the fabricated foams were measured in compression tests.A potential application for the foams considered is temporary bioresorbable bone implants,therefore the mechanical properties of the foams were compared with those of cancellous bone *** with smaller pore size and lower porosity(20 PPI and 80%±87%)exhibited mechanical properties in the lower regions of the cancellous bone property range(Young’s modulus 36.5±77.5 MPa),while foams with higher pore size and porosity(10 PPI and~90%)were found to have insufficient compression strength(Young’s modulus 11.65±23.8),but thickening their walls and lowering their porosity below 90%yielded foams with Young’s modulus between 36.5 and 77.5 *** fractures were also investigated to determine their collapse mechanism.A series of corrosion tests in stimulated body fluid was carried out to determine their applicability as a *** Plasma Electrolytic oxidation(PEo)process was used in a feasibility study to examine the microstructure and chemical composition of foams with protective coating.

关键词： Magnesium foams AZ91 investment casting Bone implants Plasma electrolytic oxidation

基于多源遥感与后向轨迹的雅安市2023年典型臭氧污染成因分析

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成都信息工程大学学报 2024年第5期39卷 626-635页

作者：吕婷婷肖杰张洋刘志红成都信息工程大学资源环境学院四川成都610225 四川省雅安生态环境监测中心站四川雅安625099

2023年4月雅安市发生较为严重的春季o_(3)污染,研究雅安市臭氧污染的现状及成因对于降低污染对当地人民健康和生态环境造成的危害、推动社会可持续发展具有重要意义。以2023年4月雅安市的两次典型o_(3)污染过程为例,基于多源遥感的地表... 详细信息

2023年4月雅安市发生较为严重的春季o_(3)污染,研究雅安市臭氧污染的现状及成因对于降低污染对当地人民健康和生态环境造成的危害、推动社会可持续发展具有重要意义。以2023年4月雅安市的两次典型o_(3)污染过程为例,基于多源遥感的地表温度、地表太阳入射辐射、o_(3)及其前体物(No_(2)和ch_(2)o)产品,结合本地高程、植被覆盖度、土地利用类型、环境站点监测资料和气象再分析资料,采用地学数理统计(相关系数r)和后向轨迹分析的方法,探究太阳辐射、地表温度和o_(3)前体物等要素对o_(3)污染的影响机制。结果表明:(1)两次污染过程o_(3)浓度变化呈现明显“单峰型”的周期性变化,峰值在13:00-19:00。(2)平均太阳辐射大于900 W/m^(2)、平均地表温度大于18℃是雅安地区发生o_(3)污染的阈值条件。(3)雅安地区天然源前体物排放对o_(3)生成的贡献不可忽略,o_(3)前体物的光化学反应主要受太阳辐射影响(|r|>0.5),而最终的o_(3)浓度则主要受温度影响(|r|>0.6)。(4)成都市的蒲江县,眉山市的洪雅县、丹棱县和东坡区是雅安市o_(3)污染的主要贡献区域。

关键词：臭氧污染驱动力分析雅安市卫星遥感后向轨迹