检索结果-南通市图书馆

Association of insertion-deletions polymorphisms with colorectal cancer risk and clinical features

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2017年第37期23卷 6854-6867页

作者： Diego Marques Layse Raynara Ferreira-costa Lorenna Larissa Ferreira-costa Romualdo da Silva Correa Aline Maciel Pinheiro Borges Fernanda Ribeiro Ito Carlos cesar de Oliveira Ramos Raul Hernandes Bortolin André Ducati Luchessi Andrea Ribeiro-dos-Santos Sidney Santos Vivian Nogueira Silbiger Laboratório de Bioanálise e Biotecnologia Molecular Universidade Federal do Rio Grande do Norte Programa de Pós-graduacao em Ciências Farmacêutica Universidade Federal do Rio Grande do Norte Laboratório de Genética Humana e Médica Universidade Federal do Pará Departamento de Cirurgia Oncológica Liga Norte Riograndense Contra o Cancer Laboratório de Patologia eCitopatologia Liga Norte Riograndense Contra o Cancer Depart-amento de Análises Clínicas e Toxicológicas Universidade Federal do Rio Grande do Norte Núcleo de Pesquisas em Oncologia Universidade Federal do Pará

AIM To investigate the association between 16 insertiondeletions(INDEL) polymorphisms, colorectal cancer(CRC) risk and clinical features in an admixed *** O n e h u n d re d a n d fo r ty p a t i e n t s w i t h C R C a n d 140 cancer-free subjects were examined. Genomic DNA was extracted from peripheral blood samples. Polymorphisms and genomic ancestry distribution were assayed by Multiplex-PCR reaction, separated by capillary electrophoresis on the ABI 3130 Genetic Analyzer instrument and analyzed on Gene Mapper ID v3.2. Clinicopathological data were obtained by consulting the patients' clinical charts, intra-operative documentation, and pathology *** Logistic regression analysis showed that polymorphism variations in IL4 gene was associated with increased CRC risk, while TYMS and UCP2 genes were associated with decreased risk. Reference to anatomical localization of tumor Del allele of NFKB1 and CASP8 were associated with more colon related incidents than rectosigmoid. In relation to the INDEL association with tumor node metastasis(TNM) stage risk, the Ins alleles of ACE, HLAG and TP53(6 bp INDEL) were associated with higher TNM stage. Furthermore, regarding INDEL association with relapse risk, the Ins alleles of ACE, HLAG, and UGT1A1 were associated with early relapse risk, as well as the Del allele of TYMS. Regarding INDEL association with death risk before 10 years, the Ins allele of SGSM3 and UGT1A1 were associated with death *** The INDEL variations in ACE, UCP2, TYMS, IL4, NFKB1, CASP8, TP53, HLAG, UGT1A1, and SGSM3 were associated with CRC risk and clinical features in an admixed population. These data suggest that this cancer panel might be useful as a complementary tool for better clinical management, and more studies need to be conducted to confirm these findings.

关键词： Colorectal cancer Ins-del polymorphism Admixed population Potential biomarker Diagnostic Risk stratification Prognostic Clinical features

The growth and production modeling of individual trees of Eucalyptus urophylla plantations

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Forestry Research 2020年第5期31卷 1663-1672页

作者： Joao Victor Nobre Carrijo Ana Beatriz de Freitas Ferreira Marcela costa Ferreira Mario cesar de Aguiar Eder Pereira Miguel Eraldo Aparecido Trondoli Matricardi Alba Valeria Rezende Department of Forestry Faculty of TechnologyUniversity of Brası´liaBrası´lia 70910-900Brazil

Individual tree models(ITMs)are classified as growth and production models for projecting current and future forest *** are more complex than other growth and production models,show a higher level of detail and,consequently,produce a better modeling ***,the accuracy and efficiency of ITMs have not been properly assessed to *** this study,we estimated the growth in height,diameter,and individual tree volume of a Eucalyptus urophylla plantation by applying an *** used a continuing forest inventory dataset in which 1554 individual trees within 29 permanent plots were measured in the field over a 6-year period(24 to 72 months).Each individual tree volume was estimated for future tree *** achieve this,we adjusted the model to predict the height and diameter growth,and the probability of mortality as a function of the competition *** ITM accuracy was assessed based on the analysis of variance results and,subsequently,the multiple mean comparison test at the 5%significance *** tree volumes predicted by the ITM for the forest stand aged 72 months,beginning at ages 24,36,48,and 60 months,were compared to the field measured tree volume acquired from the 72-month forest inventory that was used as the reference *** and observed tree volumes were similar when the estimation was based on the 48-month forest *** results might help to reduce financial costs of forest inventory because the ITM produces accurate future predictions of forest stand *** estimated ITM for Eucalyptus plantations using measurement intervals up to 2 years is recommended because it significantly reduced the projected volume discrepancy compared to the field measurements.

关键词： Competition index Forest production Forest site Simulation models Tree mortality

Synthesis and Characterization of Ni79Fe15Mo6 Nanoparticles Produced by Co-precipitation in the Presence of Organic Additives

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

材料科学与工程（中英文B版） 2021年第3期11卷 89-97页

作者： Fabio Muchenski Leonardo JoséDalla costa Paulo cesar de Camargo Ney Mattoso Instituto Federal Catarinense São Bento do SulSC 89.283-064Brazil Departamento de Física da Universidade Federal do Paraná CuritibaPR 81.531-990Brazil Departamento de Física da Universidade Federal de São Carlos São CarlosSP 13.565-905Brazil

Stable nanoparticles of Ni79Fe15Mo6(at.%)were produced by co-precipitation by NaBH4 in the presence of sucrose,ascorbic acid,and oleic *** are initially 3-10 nm in size and encapsulated by organic *** particles clump together producing stable,spherical nanoparticles with an average diameter of 36 *** analysis shows that from 600℃ no other mass loss process takes *** magnetic measurements at room temperature show a typical behavior of a soft magnetic material,with a Mr of 1.41 emu/g(22%of Ms)and a Hc of 77 *** results indicate that these nanoparticles produced by a simple,cheap,and ecologically friendly route,have a potential for diverse applications,but particularly for applications in the area of human and animal health.

关键词： Magnetic nanoparticles supermalloy co-precipitation.

Colorimetric indicators of açaíanthocyanin extract in the biodegradable polymer matrix to indicate fresh shrimp

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food Bioscience 2022年第4期48卷 601-612页

作者： Samiris Cocco Teixeira Taíla Veloso de Oliveira Rafael Resende Assis Silva Alane Rafaela costa Ribeiro Paulo cesar Stringheta Thaís Caroline Buttow Rigolon Marcos Roberto Moacir Ribeiro Pinto Nilda de Fatima Ferreira Soares Laboratory of Food Packaging Department of Food TechnologyFederal University of ViçosaViçosaMG36570-900Brazil Department of Materials Science and Engineering Federal University of S˜ao CarlosS˜ao CarlosSP13565-905Brazil Laboratory of Pigments and Bioactive Compounds Federal University of ViçosaViçosaMG36570-900Brazil Federal Institute of Espírito Santo Venda Nova do ImigranteES29375000Brazil

Colorimetric indicator or freshness indicators hold great potential to reduce food *** off açaíanthocyanins extract(AE)with different concentrations molars of two plasticizers glycerol(GLY)or triethyl citrate(TEC),for application fresh shrimp,real time were *** AE undergoes a visible pink/violet to green/yellowish color change in response to different pH’s,which is an indicator of microbial spoilage in *** CI were exposed to ammonia,and analyzed through infrared spectroscopy(FT-IR),scanning electron microscopy(SEM),ultraviolet spectroscopy,and visual *** immobilization of the plasticizers into the CA polymer matrices were confirmed through FT-IR spectra and SEM *** vitro chromatic transition of the indicators exposed to ammonia vapors,were visually more perceptible when they were produced with 7.2 mols of GLY or 1.8,3.6,and 7.2 mols of *** the real-time analysis of the application of colorimetric indicators in gray shrimp samples,the indicators that had plasticizers showed perfect color change at the exact time of food *** colorimetric indicators developed in this study using different molar concentrations of plasticizers are simple,effective and a great eco-friendly alternative to chemical sensors already developed so far.

关键词： Cellulose acetate Plasticizer Ammonia sensitivity Glycerol Triethyl citrate Spoilage Fish

Construction Processes Paradigm and Reinforcement Alternatives for Tailings Dam Soil

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Protection 2023年第3期14卷 213-229页

作者： Magno André Oliveira Lucas Redoan Cecílio Campos Marcela Cristina costa Branco Junia Lúcio de Castro Borges Gustavo Filemon costa Lima Alan Rodrigues Teixeira Machado Augusto cesar da Silva Bezerra School of Mines Geotechnics Nucleus Federal University of Ouro Preto Ouro Preto Brazil Institute of Geosciences Federal University of Pará Belém Brazil Transport Engineering Department Federal Center for Technological Education of Minas Gerais Belo Horizonte Brazil Department of Geography Federal University of Minas Gerais Belo Horizonte Brazil Department of Exact Sciences University of the State of Minas Gerais João Monlevade Brazil

In the last decade, Brazil was the scene of two of the world’s biggest disasters related to mining tailings dams. The collapse of the Mariana and Brumadinho dams was catastrophic event that brought to light major environmental and humanitarian crises. Facts like this incite debate on the safety of dam construction methods and highlight the need for a broad discussion of dam safety legislation in the country. From the above, this paper promotes a review of various forms of construction of tailings dams and their associated problems, as well as discusses the techniques for soil reinforcement and their construction methods. The work also brings an overview of the Brazilian dams from April to July 2019, tracing the context of the Brazilian tailings dams months after the tragedy of Brumadinho. The methodology includes a robust literature review and discourse analysis. In Brazil, the number of ruptured dams is alarming, especially in the state of Minas Gerais, in which more than 7 have broken in the last two decades. Among the damages, the deaths impact society abruptly and were cataloged 455 deaths, of which 216 correspond to the rupture of the dam of the Córrego do Feijão mine in Brumadinho. To evaluate and diagnose a dam, one should consider ordinance N ° 70,389, 2017 revoked by Resolution ANM n ° 95, of February 7, 2022. In this context, in March 2019, we experienced several disturbing situations regarding dam instability in the state of Minas Gerais, being categorized as risky structures. To exemplify, one can cite dams classified as level 2 risk that became level 3. Due to the above facts, several studies are being conducted to improve soil aspects. For example, we highlight the increase in soil resistance that can be done using commercial and alternative materials available in the environment.

关键词： Dams Reinforcement Rupture Minas Gerais

Model of Verbal Communication with Blind Patient:Application in Nursing Appointment

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Health 2014年第15期6卷 1919-1928页

作者： Katia Neyla de Freitas Macedo-costa Lorita Marlena Freitag Pagliuca Antonia Ferreira Alves Sampaio Paulo cesar de Almeida Cristiana Brasil de Almeida Reboucas Department of Nursing Universidade Federal da ParaíbaCampina GrandeBrazil Department of Nursing Universidade Federal do CearaFortalezaBrazil

It was aimed at validating the applicability of the Model of Verbal Communication with blind people in nursing appointment in the stages of the nursing process. A methodology of quantitative study was used with 30 nurses and 30 blind people who participated in the study, divided in control and experimental groups. 30 nursing appointments took place;they were recorded and analyzed by three judges. The experimental group had excellent performance in following protocol (95.6%);taking notes informing the reason for silence (93.4%);and avoiding long silence (100%). In interventions, it presented excellence in all the items, in the evaluation stage, there were no bad/terrible actions. In none of the actions the control group presented better performance than the experimental one. The use of the Model is recommended in nursing appointment with blind patient.

关键词： Communication Nursing Visually Impaired Patients Disabled Patients Humanization of Assistance

Ultrastructure of compatible and incompatible interactions in phloem sieve elements during the stylet penetration by cotton aphids in melon

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Insect Science 2018年第4期25卷 631-642页

作者： Elisa Garzo Mercedes Fernandez-Pascual cesar Morcillo Alberto Fereres M. Luisa G6mez-Guillamon W. Fred Tjallingii Instituto de Ciencias Agrarias Consejo Superior de Investigaciones Cientificas (ICA-CSIC) Madrid Spain Laboratory of Entomology Wageningen University Wageningen the Netherlands Instituto de Hortofruficultura Subtropical y Mediterranea 'La Mayora' Universidad de Malaga-CSIC (IHSM-UMA-CSIC) Algarrobo-Costa Malaga Spain

Resistance of the melon line TGR-1551 to the aphid Aphis gossypii is based on preventing aphids from ingesting phloem sap. In electrical penetration graphs （EPGs）, this resistance has been characterized with A. gossypii showing unusually long phloem salivation periods （waveform El） mostly followed by pathway activities （waveform C） or if followed by phloem ingestion （waveform E2）, ingestion was not sustained for more than 10 min. Stylectomy with aphids on susceptible and resistant plants was performed during EPG recording while the stylet tips were phloem inserted. This was followed by dissection of the penetrated leaf section, plant tissue fixation, resin embedding, and ultrathin sectioning for transmission electron microscopic observation in order to study the resistance mechanism in the TGR. The most obvious aspect appeared to be the coagulation of phloem proteins inside the stylet canals and the punctured sieve elements. Stylets of 5 aphids per genotype were amputated during sieve element （SE） salivation （El） and SE ingestion （E2）. Cross-sections of stylet bundles in susceptible melon plants showed that the contents of the stylet canals were totally clear and also, no coagulated phloem proteins occurred in their punctured sieve elements. In contrast, electron-dense coagulations were found in both locations in the resistant plants. Due to calcium binding, aphid saliva has been hypothesized to play an essential role in preventing/suppressing such coagulations that cause occlusion of sieves plate and in the food canal of the aphid＇s stylets. Doubts about this role of E 1 salivation are discussed on the basis of our results.

关键词： Aphis gossypii Glover Cucumis melo L. feeding behavior insect-plant resistance phloem defense response watery saliva

Antibiofilm and immunomodulatory resorbable nanofibrous filing for dental pulp regenerative procedures

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bioactive Materials 2022年第10期7卷 173-186页

作者： Mauricio Gonçalves da costa Sousa Gabriela Conceiçao de Almeida Danilo cesar Martins Mota Rosiane Andrade da costa Simoni Campos Dias Samuel Nunes Limberger Frank Ko Li Ting Lin Evan FHaney Hashem Etayash Beverlie Baquir Michael J.Trimble Ya Shen Zheng Su Markus Haapasalo Daniel Pletzer Letícia Chaves de Souza Glaucia Schuindt Teixeira Renato M.Silva Robert E.W.Hancock Octavio Luiz Franco Taia Maria Berto Rezende Post-Graduation Program in Genomic Sciences and Biotechnology Catholic University of BrasíliaBrasíliaBrazil Dentistry Course Catholic University of BrasíliaBrasíliaBrazil Post-Graduation Program in Health Sciences University of BrasíliaBrazil LIMA Chemistry InstituteUniversity of Brasília-UNBBrasíliaBrazil Animal Biology Department Campus Darcy RibeiroUniversidade de BrasíliaBrazil Department of Materials Engineering Faculty of Applied ScienceUniversity of British ColumbiaVancouverCanada Department of Microbiology and Immunology University of British ColumbiaVancouverBCCanada Department of Oral Biological and Medical Sciences Faculty of DentistryUniversity of British ColumbiaVancouverCanada Department of Microbiology and Immunology University of OtagoDunedinNew Zealand Department of Endodontics School of DentistryUniversity of Texas Health Science Center at HoustonHoustonUSA Department of Prosthesis Faculty of DentistryRio de Janeiro State UniversityRio de JaneiroBrazil Post-Graduation Program in Biotechnology Catholic University Dom BoscoCampo GrandeMato Grosso do SulBrazil

Multifunctional scaffolds with host defense peptides designed for regenerative endodontics are desirable nanobiotechnological tools for ***,different scaffolds were tested for use during the pulp revascularization process,including poly(vinyl alcohol)-PVA hydrogels or resins,collagen hydrogels and poly(vinyl alcohol)PVA/Chitosan(PVA/CS)*** on time to degradation(21 days),nanofibers were chosen to be incorporated with ciprofloxacin and IDR-1002(each at 50 mg/g).Nanofibers containing ciprofloxacin and IDR-1002 had anti-biofilm activity against Enterococcus faecalis,Staphylococcus aureus and a multispecies oral biofilm,besides anti-inflammatory *** in vivo subcutaneous tissue response to tooth fragments filled with nanofibers demonstrated a pulp-like tissue formation,when compared to empty teeth ***,we designed a strong antimicrobial,immunomodulatory and regenerative candidate for pulp revascularization and regeneration procedures.

关键词： Regenerative endodontics Scaffolds Nanofibers Host defense peptides Ciprofloxacin IDR-1002

Support Vector Machine and Artificial Neural Networks for Hydrological Cycles Classifications of a Water Reservoir in the Amazon

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

通讯和计算机（中英文版） 2014年第2期11卷 111-117页

作者： Jean Carlos Arouche Freire Tarcisio da costa Lobato Jefferson Magalhaes de Morais Terezinha Ferreira de Oliveira Rachel Anne Hauser-Davis Augusto cesar Fonseca Saraiva Faculty of Computing Federal University of Pard City Belem 66. 075-110 Brazil Faculty of Mathematics and Statistics Federal University of Para Belem 66. 075-110 Brazil Departament of Chemmistry Pontifical Catholic University of Rio de Janeiro Rio de Janeiro 22451-900 Brazil Technology Center Eletrobras-Eletronorte Belem 66115-000 Brazil