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网络安全量化评估系统的研究与应用

计算机科学 2003年第2期30卷 100-104页

作者：夏阳陆余良蒋凡解放军电子工程学院网络工程教研室合肥230037 中国科学技术大学信息网络安全研究中心合肥230027

The rapid development of the Network makes the comprehensive analysis as well as the quantitative evaluation of its security become more and mere important. This paper illustrates the major realization process of a Network Security Quantitative Evaluation System,which,from an intruder's angle ,established a Hierarchy Intrusion Relationship Graph by analyzing the credit degree fusion and relevancy of the secure information of the target network and by combining with powerful database information. At last, by applying some relative mathematics model and arithmetic, the paper analyzes and evaluates the security of this Network Hierarchy Intrusion Relationship Graph comprehensively and quantitatively.

关键词：网络安全量化评估系统计算机网络逆向工程脆弱性

认知语义学与新一代双语/双解学习词典的多维释义

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外语教学与研究 2010年第5期42卷 374-379页

作者：章宜华广东外语外贸大学文科基地词典学研究中心广东省广州市510420

目前的主流英语学习词典都来自英国,其设计和编纂主要以西方人的认知思维为参照,按传统的语言学理论将语言系统分块解释,以语法为中心孤立地组织词汇信息,难以满足中国用户二语习得的需要。本文用认知语义学的理论方法,在分析五大学习... 详细信息

目前的主流英语学习词典都来自英国,其设计和编纂主要以西方人的认知思维为参照,按传统的语言学理论将语言系统分块解释,以语法为中心孤立地组织词汇信息,难以满足中国用户二语习得的需要。本文用认知语义学的理论方法,在分析五大学习词典缺陷的基础上,从词典释义的国别针对性以及语言认知的百科性、多维性和整体性等角度来阐释新一代双语学习词典的多维释义,并通过释义在词典中构建词汇-语义关系网络,以便为二语学习者提供足够的可理解输入,提高其语言习得的效率。

关键词：认知语义学双语词典多维释义释义原则

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论首都高校太极推手比赛改革与创新

中华武术（研究） 2015年第3期4卷 15-18页

作者：王超刘明亮首都师范大学初等教育学院体育教研室北京100089 国际关系学院体育美育教研部北京100091

文章运用专家访谈法、逻辑分析法等研究方法,对太极推手比赛在竞赛内容、组织规程和规则上做了系统调研,并结合首都高校的自身特点和现有状况在北京市太极推手竞赛的基础上做了系统的改革与创新,为打造出首都高校自己的太极推手比赛做... 详细信息

文章运用专家访谈法、逻辑分析法等研究方法,对太极推手比赛在竞赛内容、组织规程和规则上做了系统调研,并结合首都高校的自身特点和现有状况在北京市太极推手竞赛的基础上做了系统的改革与创新,为打造出首都高校自己的太极推手比赛做出了理论探索。

关键词：首都高校改革创新太极推手

SUPPRESSION OF TISSUE INHIBITOR OF METALLOPROTEINASE-1（TIMP-1） GENE EXPRESSIONBY RECOMBINANT ADENO-ASSOCIATED VIRUSCARRYING SMALL INTERFERENCE （SIRNA） OF TIMP-1IN RAT HEPATIC STELLATE CELL（HSC）

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SUPPRESSION OF TISSUE INHIBITOR OF METALLOPROTEINASE-1（TIMP...

Identification of over-expressed genes in human renal cell carcinoma by combining suppression subtractive hybridi-zation and cDNA library array

首届国际中西医结合肝病学术会议

作者： CONG Min WANG Ping LIU Tianhui TANG Shuzhen WANG Baoen JIA Jidong LIU Yong YOUHongLiver research center Beijing Friendship Hospital capital {3. of Medical Sciences Beijing’100050 P.R. China

＜正＞ AIMS: Elevated tissue inhibitor of metalloproteinase-1 （TIMP-1） expression contributes to excess extracellular matrix in liver fibrosis. The study was designed to construct recombinant adeno -associated virus （AAV） carrying siRNA of TIMP-1 and investigate the long-term effect of TIMP-1 gene RNA interference on rat hepatic stellate cell （HSC） -T6 cells in ***:Five siRNA oligomers targeting rat TIMP-1 at nt161-183. nt 190-208, nt 208-226, nt 226 -244 and nt 445- 463.were transfected into rat HSC-T6 cells respectively. U6 promotor followed by the annealing siRNA which had the strongest suppression effect were cloned into the AAV vector and packed in 293.cells to construct the recombinant AAV/siRNA- TIMP- 1/neo. After infecting this recombinant AAV into rat HSC- T6 cells and selection by G418, real- time PCR after reverse transcription and Western blot were performed to detect the transcription and expression level of TIMP -1 gene in HSC-T6 cells at 1 and 3.***:It was demonstrated that 2 of the 5 siRNA oligomers had the significant effect on suppressing TIMP-1 expression by Western-blot whithin 72 hours after transfecting into rat HSC -T6 cells. The amplified rat U6 promotor by PCR using the DNA of infected cells by the recombinant AAV /siRNA -TIMP -1/neo as template proved that the HSC -T6 cells could continually express siRNA-TIMP-1 for 3.months after infection. The transcription and expression level of TIMP -1 in HSC-T6 cells which were infected by the recombinant AAV were suppressed dramatically compared with mock control and normal HSC-T6 cells （P＜0. 05）, and the expression level of TIMP-1 gene in HSC-T6 cells infected after 3.months decreased significantly （90%） compared with those infected after 1 months （ 60%）. CONCLUSIONS:RNA interference can exert an suppression of TIMP-1 gene in rat HSC, and when this faction combined *** infection , it can suppress the specific gene expression for a long time by chromosomal integration.

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Science China(Life Sciences) 2004年第2期47卷 148-157页

作者： AI Junkui1, ZHANG Zhiwen2, XIN Dianqi1, ZHU Hongjian1, YAN Quanjian3. XIN Zhongcheng1, NA Yanqun1 & GUO Yinglu1 1. Institute of Urology, Peking university & Department of Urology, First Hospital, Peking university, Beijing 10003., China 2. Department of Physiology, Peking university Health Science {3., Beijing 100083. China 3. Department of Urology, Xijing Hospital, the 4th Military Medical university, Xi抋n 71003., China Institute of Urology Peking University & Department of Urology First Hospital Peking University Beijing 100034 China Department of Physiology Peking University Health Science Center Beijing 100083 China Department of Urology Xijing Hospital the 4th Military Medical University Xi'an 710033 China

To isolate the over-expressed genes in human renal cell carcinoma (RCC) and analyze its molecular basis of carcinogenesis, we used the mRNA from human RCC tissues as tester and that from the matched normal kidney tissues as driver to construct the suppression subtractive hybridization library. 3.9 of the subtracted clones were arrayed onto a nylon mem-brane and the over-expressed genes were then screened by hybridizing the filter with radioac-tively labeled cDNA from RCC and matched normal kidney tissues. 67 clones over-expressed in RCC by a factor of 6 or more were sequenced and its identities were analyzed in GenBank da-tabase. 4 clones were previously unknown fragments and 2 clones represent KIAA genes. The rest clones were the known genes and some of them were RCC-related, including vascular en-dothelial growth factor, vimentin and tissue factor. Most of the known genes were the RCC-related genes previously unknown, including zinc ribbon domain-containing 1 protein (ZNRD1), pituitary tumor transforming gene1 (PTTG1). Northern blot and semi-quantitative RT-PCR confirmed that the mRNA levels of the 3.novel fragments and 1 KIAA and 3.known genes were significantly higher in RCC than in the matched normal kidney tissues. Immunohis-tochemical and Western blot analysis for PTTG1 and ZNRD1 revealed increased protein level in RCC. The over-expressed genes in RCC are the potential molecular targets for diagnosis and therapy and it is very important to understand the molecular mechanism of RCC through the profile of over-expressed genes.

关键词： suppression subtractive hybridization (SSH), cDNA microarray, renal cell carcinoma (RCC), gene, differential expression.

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解读徽州文化的三种文化空间

学术界 2011年第12期163卷 81-88,284页

作者：张祖群首都经济贸易大学工商管理学院旅游管理系北京100070 中国科学院地理科学与资源研究所博士后流动站北京100101

徽州文化绝非是静止不动的,等待学者阅读的"死去"文本。那么如何以动态的观点借鉴新文化地理学的框架重新解读徽州文化?文章构筑了实体文化空间、经济文化空间与符号文化空间三个层面的研究框架。实体文化空间表现在:徽商在新安江流域... 详细信息

徽州文化绝非是静止不动的,等待学者阅读的"死去"文本。那么如何以动态的观点借鉴新文化地理学的框架重新解读徽州文化?文章构筑了实体文化空间、经济文化空间与符号文化空间三个层面的研究框架。实体文化空间表现在:徽商在新安江流域充分利用自然环境本体营造聚落民居,在新安江流域营造水口园林形成独特景致,在离居地中心营建私家建筑园林形成园林空间的异地移植。经济文化空间表现在:徽商重视原始资本积累与资本的空间回流,在内外交困中历经兴衰的时空转折,并且比较了徽商没能复活的不同经济文化空间。符号文化空间表现在:徽州山水画创作和积累,在纸上再现徽州文化符号。徽商影视剧在荧屏上再现徽州文化符号。最后讨论认为这三种文化空间共同构建了复合的乡村文化共同体。

关键词：实体文化空间经济文化空间符号文化空间乡村文化共同体

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密云水库水体营养状态分析

水生生物学报 2004年第2期28卷 191-196页

作者：杜桂森刘晓端刘霞葛晓立潘小川首都师范大学生物系北京100037 国家地质实验测试中心北京100037 北京大学公共卫生学院北京100083

调研结果显示 ,密云水库的营养特征为浮游藻类响应型。浮游藻类的群落结构是绿藻 (Chlorophyta)—硅藻(Bacillariophyta)型。库区水体TN 0 86mg/L ,TP 0 .0 2 2mg/L ,浮游藻类的细胞密度 4 0 5 2 3. 10 4/L。 4项指标 (Tr、TP、CODmn... 详细信息

调研结果显示 ,密云水库的营养特征为浮游藻类响应型。浮游藻类的群落结构是绿藻 (Chlorophyta)—硅藻(Bacillariophyta)型。库区水体TN 0 86mg/L ,TP 0 .0 2 2mg/L ,浮游藻类的细胞密度 4 0 5 2 3. 10 4/L。 4项指标 (Tr、TP、CODmn、chla)的TSIM 值 4 0 1— 4 9 6 ,水体为中营养。但TN、TP和浮游藻类细胞密度增长较快 ,水体向富营养发展的趋势明显。主要制约因素是面源、点源和内源对水体的污染。北京市水资源紧缺 ,密云水库是主要饮用水源地。保护流域生态环境 ,治理污染 ,涵养水源。

关键词：密云水库浮游藻类中营养水源保护

research ON APPLICATIONS OF STOCHASTIC PROCESS IN MODELING PLANT GROWTH

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RESEARCH ON APPLICATIONS OF STOCHASTIC PROCESS IN MODELING P...

Association between single nucleotide polymorphisms(SNPs) on the promoter of adiponcctin gene,hypoadiponectinemia, and diabetes

第四届智能化农业信息技术国际学术会议

作者： Ying Xiong~(1 2) Changfeng Li~1 Shenglian Lu~1 Xinyu Guo~1 1 National Engineering research center for Information Technology in Agriculture Beijing 100097 China 2 capital Normal {3. Beijing 10003. China

＜正＞This paper gives an overview to stochastic process,especially the mathematic definition, evolving history and applications of Markov stochastic ***,models and applications using Markov stochastic process to simulate and visualize plant growth are introduced in detail. Appraisal to these models are given following by a perspective to the simulating of plant growth.

关键词： Markov Process Plant Growth Modeling Stochastic L-System Reference Axis Dual-scale

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Association between single nucleotide polymorphisms(SNPs) on...