检索结果-南通市图书馆

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

氩氪激光治疗小脉络膜恶性黑色素瘤效果分析

中华眼科杂志 1993年第1期29卷 36-39,T002页

作者： Jame.,dc 赵强 121001，锦州医学院附属医院眼科澳大利亚墨尔本大学眼科系皇家维多利亚眼耳医院

回顾性分析8例小脉络膜恶性黑色素瘤经氩氪激光治疗的结果。其中男性7例,女性1例。平均随访时间56个月。平均光凝治疗11次。8例中5例(62.5%)肿瘤临床消退,肿瘤体积在1.0mm×1.2mm×1.5mm至4.5mm×6.0mm×2.5mm之间。3例(37.5%)肿瘤临床... 详细信息

回顾性分析8例小脉络膜恶性黑色素瘤经氩氪激光治疗的结果。其中男性7例,女性1例。平均随访时间56个月。平均光凝治疗11次。8例中5例(62.5%)肿瘤临床消退,肿瘤体积在1.0mm×1.2mm×1.5mm至4.5mm×6.0mm×2.5mm之间。3例(37.5%)肿瘤临床复发,肿瘤体积在4.0mm×2.0mm×3.5mm至11.5mm×12.5mm×3.5mm之间。治疗的并发症包括视网膜分支静脉阻塞、视网膜新生血管生成、玻璃体出血、黄斑水肿和视神经萎缩。治疗结果提示激光治疗小脉络膜恶性黑色素瘤有效。

关键词：脉络膜肿瘤黑色素瘤激光疗法

Antidiarrhoeal activity of leaf methanolic extract of Rauwolfia serpentina

在线全文

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Biomedicine 2012年第6期2卷 430-432页

作者： Ezeigbo II Ezeja MI Madubuike KG Ifenkwe dc Ukweni IA Udeh NE Akomas SC Department of Veterinary Physiology Biochemistry and Pharmacology College of Veterinary Medicine Michael Okpara University of Agriculture

Objective:To evaluate the antidiarrhoeal property of methanol extract of the leaves of Rauwolfia serpentina(R. serpentina) in experimental diarrhoea induced by castor oil in ***:Doses of 100, 200 and 400 mg/kgR. serpentinaleaf methanol extracts were administered to castor oil induced diarrhoea mice to determine its antidiarrhoeal ***:All doses of the extract and the reference drug atropine sulphate(3 mg/kg, i.p.) produced a dose-dependent reduction in intestinal weight and fluid volume. The extracts also significantly reduced the intestinal transit in charcoal meal test when compared to diphenoxylate Hcl(5 mg/kg, p.o.).Conclusions:The results show that the extract of R. serpentin a leaves has a significant antidiarrhoeal activity and supports its traditional uses in herbal medicine.

关键词： Rauwolfia serpentina Castor oil Antidiarrhoeal activity Intestinal transit

Reduced gastric acid production in burn shock period and its significance in the prevention and treatment of acute gastric mucosal lesions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2000年第1期6卷 84-88页

作者： Zhu L Yang ZC Li A Cheng dc Institute of Burn Research Southwest HospitalThird Military Medical UniversityChongqing 400038China Critical Care Department Peking Union Medical College Hospital(PUMCH)Chinese Academy of Medical Sciences(CAMS)Beiling 100730China

AIM To investigate the changes of gastric acidproduction and its mechanism in shock period ofsevere burn in *** A rat model with 30% TBSA full-thickness burn injury was employed and thegastric acid production,together with gastricmucosal blood flow(GMBF)and energy charge(EC)were measured serially within *** The gastric acid production in theacute shock period was markedly inhibited aftersevere burn *** the 3rd h postburn,thegastric juice volume,total acidity and acidoutput were already significantly decreased(P<0.01),and reached the lowest point,0.63mL/L±0.20mL/L,10.81mmol/L±2.58mmol/L and 2.23mmol/h±0.73mmol/hrespectively,at the 12th h *** to some degree 24 h after thermalinjury,the variables above were stillstatistically lower,compared with those ofcontrol animals at the 48th h *** and EC were also significantly reducedafter severe burns,consistent with the trend ofgastric acid production *** Gastric acid production,as wellas GMBF and EC was predominantly decreased in the early postburn stage,suggesting that gastricmucosal ischemia and hypoxia with resultantdisturbance in energy metabolism,but notgastric acid proper,might be the decisive factorin the pathogenesis of AGML after thermalinjury,and that the preventive use of anti-aciddrugs during burn shock period wasunreasonable in some ***,taking effective measures to improve gastricmucosal blood perfusion as early as possiblepostburn might be more preferable for the AGMLprevention and treatment.

关键词： Subject headings gastric mucosal lesions gastric acid burn shock

Protective effect of early enteral feeding on postburn impairment of liver function and its mechanism in rats

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2000年第1期6卷 79-83页

AIM To study the protective effect of earlyenteral feeding(EEF)on the postburnimpairment of liver function and its *** Wistar rats with 30% of total bodysurface area(TBSA)full-thickness burn *** effects of EEF on the postburnchanges of gastric intramucosal pH,endotoxinlevels in portal vein,water contents of hepatictissue,blood concentrations of tumor necrosisfactor(TNF-α),plasma activities of alanineaminotransferase(ALT)and asparateaminotransferase(AST),as well as the bloodcontents of total(TB)and direct bilirubin(DB),total protein(TP)and albumin(ALB)wereserially determined within 48h *** EEF could significantly improvegastric mucosal acidosis,reduce portal veinendotoxin level and water content of hepatictissue,as well as plasma concentrations of TNF-α at all timepoints after severe burns(P<0.01);postburn elevation of the plasma activities ofALT,AST and the contents of TB,DB wereeffectively prevented,whereas the plasmaconcentrations of TP and ALB were markedlyincreased 24 h and 48 h posturn in EEF groupcompared with that of the burn without EEFgroup(P<0.01).CONCLUSION EEF has significant beneficialeffects on the improvement of hepatic function in rats after severe burn,and is probably relatedwith an increase in splanchnic blood flow,reduction of the absorption of gut-originendotoxin and the consequent release ofinflammatory mediators.

关键词： Subject headings early enteral feeding liver postburn impairments

Properties of matter matter in assessment of scald injuries.

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Properties of matter matter in assessment of scald injuries.

第八届全国烧伤外科学年会

作者： Chiu TW Ng dc Burd A Division of Plastic and Reconstructive Surgery Department of SurgeryThe Chinese University of Hong KongPrince of Wales HospitalHong Kong

＜正＞Gathering information on the thermal characteristics of the causative agent in scald injuries provides clues as to the likely depth of *** theorize that viscosity and thermal capacity may have important roles to play when we view scalds as contact burns due to a *** a 4-year review of our scald patients,we found that scalds due to thick food/drinks such as congee （a porridge made from rice） were associated with a higher rate of *** determined the rate of cooling of seven common food/drinks and found little difference between water,tea,coffee and noodles,other than the starting ***,the rate of cooling of congee was significantly slower indicating a greater thermal capacity.A "drip" model found that a skin substitute exposed to congee cooled significantly more slowly compared to other food/drinks, suggesting that its greater viscosity plays a *** supports the theory that the viscosity of food/drink is important.

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

美国卫生保健资源分配的讨论

国外医学（卫生经济分册） 1992年第4期9卷 173-177页

作者： Hadom dc 齐鲁

美国在卫生保健方面当前存在的问题,促使人们要尽早采取相应措施。虽曾就如何降低日益高涨的医疗费用,以及增加低收入和未参加医疗保险者的就医机会等,提出过多种解决办法,但迄今为止对一些关键性专用词仍存在着理解和解释上的分歧,倘... 详细信息

美国在卫生保健方面当前存在的问题,促使人们要尽早采取相应措施。虽曾就如何降低日益高涨的医疗费用,以及增加低收入和未参加医疗保险者的就医机会等,提出过多种解决办法,但迄今为止对一些关键性专用词仍存在着理解和解释上的分歧,倘能尽快统一定义,则将会有助于推进这场意见纷纭、旷日持久的讨论。为此,笔者倡议使用以下三项解释:(1)配给:是指参照必要的卫生保健服务指标,对享受不均进行的必要调剂;(2)保健需求:是指已被充分证明能以纯津贴方式的病人有效地提供针对性必需的临床服务;(3)基本津贴计划:是指为所有参照相应临床指标认可的必要保健需求提供详尽的保险金计划。

关键词：美国医疗费用卫生保健

Tissue engineering in burn scar reconstruction

在线全文

学校读者我要写书评

暂无评论

Burns & Trauma 2015年第3期3卷 122-132页

作者： PPM van Zuijlen KLM Gardien MEH Jaspers EJ Bos dc Baas AJM van Trier E Middelkoop Burn Center Red Cross HospitalBeverwijkThe Netherlands Department of Plastic Reconstructive and Hand SurgeryRed Cross HospitalBeverwijkThe Netherlands Association of Dutch Burn Centers BeverwijkThe Netherlands Department of Plastic Reconstructive and Hand SurgeryMOVE Research InstituteVU University Medical CenterAmsterdamThe Netherlands

Nowadays,most patients with severe burns will survive their *** evolution is accompanied by the challenge to cover a large percentage of total body surface area ***,more and more patients have to deal with the sequelae of burn scars and require(multiple)*** review provides a gross overview of developments in the field of tissue engineering for permanent burn wound coverage and reconstructive burn surgery,focusing on usage and clinical *** only skin substitutes will be discussed but also the replacement of subcutaneous fat tissue and cartilage.

关键词： Burns Tissue engineering Scar Contracture Substitute Subcutaneous fat tissue Cartilage Reconstruction

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

溶血性阿卡诺杆菌的生物学与人类的疾病

国外医学（儿科学分册） 1992年第5期19卷 255-257页

作者： Waagner dc 孔梅

溶血性阿卡诺杆菌是青年和青少年非链球菌咽炎的主要病原菌。该菌在上呼吸道感染中的作用正逐渐受到重视。溶血性阿卡诺杆菌咽炎的好发年龄为10～30岁,临床上具有独特的皮疹。此外,还可出现其它部位的感染。长期以来由于临床医师的主观... 详细信息

溶血性阿卡诺杆菌是青年和青少年非链球菌咽炎的主要病原菌。该菌在上呼吸道感染中的作用正逐渐受到重视。溶血性阿卡诺杆菌咽炎的好发年龄为10～30岁,临床上具有独特的皮疹。此外,还可出现其它部位的感染。长期以来由于临床医师的主观原因和检查手段的不适应,这种可治愈的疾病常被遗漏。

关键词：溶血性阿卡诺杆菌生物学咽炎

Association of farnesyl diphosphate synthase polymorphisms and response to alendronate treatment in Chinese postmenopausal women with osteoporosis

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2014年第4期127卷 662-668页

作者： Liu Y Li M Zhou PR Xing XP Xia WB Xu L Liu H J Zhang ZL LiaoEY Chen dc Liu J Tao TZ Wu W Department of Endocrinology Key Laboratory of EndocrinologyMinistry of HealthPeking Union Medical College Hospital Peking Union Medical College Chinese Academy of Medical Sciences Beijing 100730 China Department of Endocrinology People&#39 s Hospital of Liaocheng Liaocheng Shandong 252002 China Metabolic Bone Disease and Genetics Research Unit Department of Osteoporosis and Bone Diseases Shanghai Sixth People&#39 s Hospital Affiliated with Shanghai Jiao Tong University Shanghai 200233 China Osteoporosis and Bone Diseases Shanghai Sixth People's HospitalAffiliated with Shanghai Jiao Tong University Shanghai 200233China Institute of Endocrinology and Metabolism Second Xiangya Hospitalof Central South University Changsha Hunan 410011 China Department of Endocrinology Osteoporosis Education Center WestChina Hospital Sichuan University Chengdu Sichuan 610041China Department of Orthopedics Xijing Hospital Fourth Liberation ArmyUniversity Xi'an Shannxi 710032 China Department of Orthopedics Harbin Medical University AffiliatedSecond Hospital Harbin Heilongjiang 150081 China Department of Endocrinology Guangdong General HospitalGuangzhou Guangdong 510080 China

Background Genetic factors are important in the pathogenesis of osteoporosis,but less is known about the genetic determinants of osteoporosis *** aimed to explore the association between the gene polymorphisms of key enzyme farnesyl diphosphate synthase （FDPS） in mevalonate signaling pathway of osteoclast and response to alendronate therapy in osteoporotic postmenopausal women in *** The study group comprised 639 postmenopausal women aged （62.2＆#177;7.0） years with osteoporosis or osteopenia who had been randomly assigned to low dose group （70 mg/2w） or standard dose group （70 mg/w） of alendronate in this 1-year *** identified allelic variant of the FDPS gene using the polymerase chain reaction and restriction enzyme *** and after treatment,serum levels of calcium,phosphate,alkaline phosphatase （ALP）,cross linked C-telopeptide of type Ⅰ collagen （β-CTX） were *** mineral density （BMD） at lumbar spine and proximal femur was *** association was analyzed between the polymorphisms of FDPS gene and the changes of BMD,bone turnover biomarkers after the *** The FDPS rs2297480 polymorphisms were associated with baseline BMD at femoral neck,and patients with CC genotype had significantly higher baseline femoral neck BMD （（733.6＆#177;84.1） mg/cm2） than those with AC genotypes （（703.0＆#177;86.9） mg/cm2） and AA genotypes （（649.8＆#177;62.4） mg/cm2）（P 〈0.01）.No significant difference in BMD at lumbar spine was observed among different genotypes of *** percentage change of serum ALP level was significantly lower in patients with CC genotype （-22.9%） than that in those with AC genotype （-24.1%） and AA genotype （-29.8%） of FDPS after 12 months of alendronate treatment （P 〈0.05）.Neither percentage change of BMD nor β-CTX level after alendronate treatment had association with FDPS *** FDPS gene was probably a candidate gene to predict femoral neck BMD at *** gene alleles could predict chan

关键词： farnesyl diphosphate synthase polymorphism alendronate osteoporosis pharmacogenomics