检索结果-南通市图书馆

Investigation of different pre-treatments of chromium leather shavings to improve biogas production

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Leather Science and Engineering 2020年第1期2卷 146-159页

作者： carolina Scaraffuni Gomes Jens-Uwe Repke Michael Meyer Forschungsinstitut für Leder und Kunststoffbahnen(FILK)gGmbH MeiBner Ring 1-509599 FreibergGermany Dynamik und Betrieb technischer Anlagen TU BerlinStraße des 17.Juni 13510623 BerlinGermany

Chromium shavings are wet by-products of the leather industry,of which thousands of tons accrue worldwide during leather *** to their chromium content,chromium shavings are responsible for the most important ecological challenges caused by the leather *** are stable towards temperatures of up to 110°C and enzymatic *** high stability is caused by the three-dimensional native structure,typical for collagen,and additional chemical cross-links between the collagen fibres achieved by Cr3+salts in the tanning ***,hitherto chromium shavings are not utilized industrially to produce *** order to generate biogas,this stable structure has to be *** shavings were pre-treated by extrusion and hydrothermal *** prove the enzymatic degradability,the different pre-treatments were evaluated by differential scanning calorimetry(DSC),enzymatic assays,and by measuring the solubility in *** biogas production potential was investigated using batch trials to examine *** demonstrated that both pretreatments allowed enzymatic attack and increased degradability of the chromium shavings reducing the lag-phase of biogas production and the remaining waste.

关键词： Biogas production Anaerobic digestion Chromium shavings Extrusion Hydrothermal treatment

Experimental approaches to select tree species for forest restoration:effects of light,water availability and interspecific competition in degraded areas

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Forestry Research 2022年第4期33卷 1197-1207页

作者： Johanna Croce Ernesto I.Badano carolina B.Trigo Fernanda Martinez-Galvez Andrés Tálamo Laboratorio de Ecología Aplicada a la Conservación Instituto de Bio y Geociencias del Noroeste ArgentinoConsejo de Investigaciones Científi cas y Técnicas-Universidad Nacional de SaltaAvenida Bolivia 51504400 SaltaArgentina IPICYT/División de Ciencias Ambientales Instituto Potosino de Investigación Científi ca y TecnológicaCamino a la Presa San José2055Colonia Lomas 4^(a)Sección78216 San Luis PotosíMéxico

Knowing what native trees can recr uit on degraded areas allows selecting the best species to restore these ***,as this information is not often available,experimentation is required before large-scale *** study used ex situ experiments to make these decisions on *** with r-strategist plants,excessive solar radiation and water shortage commonly impair tree recruitment in open *** experiments focused on the interactions among these factors and were conducted with three pioneer species from seasonally dry forests of northwest Argentina,Anadenanthera colubrina,Ceiba chodatii and Jacaranda *** of each species were sown at two light levels(sunlight/shade),two rainfall levels(full/reduced)and two levels of interspecific competition(with/without competitor)in a tree *** emergence and survival were monitored over a year and the results indicate that species differentially respond to varying levels of light and *** of *** tolerated water shortages under elevated solar radiation,which are desirable features for forest *** of *** tolerated shade and drought,suggesting that they require shading for establishing in open ***,*** seedlings neither tolerated full sunlight nor water shortages,suggesting that this species requires shading and regular watering if used in *** of the effects of light and water,the survival of all species was reduced by interspecific *** results highlight the importance of experimentation for selecting the best species for forest restoration and can enhance the cost/benefit ratios of these actions.

关键词： Common-garden experiments Drought Ecological restoration Interspecific competition Seedling survival Shade

Crop residues: applications of lignocellulosic biomass in the context of a biorefinery

在线全文

学校读者我要写书评

暂无评论

Frontiers in Energy 2022年第2期16卷 224-245页

作者： Maria carolina ANDRADE Caio de Oliveira GORGULHO SILVA Leonora Rios de SOUZA MOREIRA Edivaldo Ximenes FERREIRA FILHO Laboratory of Enzymology Department of Cellular BiologyUniversity of BrasiliaBrasiliaDFBrazil

Interest in lignocellulosic biomass conversion technologies has increased recently because of their potential to reduce the dependency on non-renewable feedstocks. Residues from a variety of crops are the major source of lignocellulose, which is being produced in increasingly large quantities worldwide. The commercial exploitation of crop residues as feedstocks for biorefineries which could be used to produce a variety of goods such as biofuels, biochemicals, bioplastics, and enzymes is an attractive approach not only for adding value to residues but also for providing renewable products required by the expanding bioeconomy market. Moreover, the implementation of biorefineries in different regions has the potential to add value to the specific crop residues produced in the region. In this review, several aspects of crop residue application in biorefineries are discussed, including the role of crop residues in the bioeconomy and circular economy concepts, the main technical aspects of crop residue conversion in biorefineries, the main crop residues generated in different regions of the world and their availability, the potential value-added bioproducts that can be extracted or produced from each crop residue, and the major advantages and challenges associated with crop residue utilization in biorefineries. Despite their potential, most biomass refining technologies are not sufficiently advanced or financially viable. Several technical obstacles, especially with regard to crop residue collection, handling, and pre-treatment, prevent the implementation of biorefineries on a commercial scale. Further research is needed to resolve these scale-up-related challenges. Increased governmental incentives and bioeconomic strategies are expected to boost the biorefinery market and the cost competitiveness of biorefinery products.

关键词： crop residue biorefinery bioproduct biomass circular bioeconomy enzyme

Human bocavirus in children hospitalized for acute respiratory tract infection in Rome

在线全文

学校读者我要写书评

暂无评论

World Journal of Pediatrics 2020年第3期16卷 293-298页

作者： Laura Petrarca Raffaella Nenna Antonella Frassanito Alessandra Pierangeli Greta Di Mattia carolina Scagnolari Fabio Midulla Maternal-Infantile and Urological Science Department "Sapienza"University of RomeRomeItaly Virology Laboratory Department of Molecular Medicine"Sapienza"University of RomeRomeItaly

Background The role of human bocavirus (HBoV) as a respiratory pathogen has not been fulfilled *** aimed to describe clinical and serological characteristics of children with HBoV hospitalized for acute respiratory tract infection and to evaluate whether differences occur between HBoV alone and in *** We retrospectively reviewed data from 60 children (median age of 6.2 months,range 0.6-70.9) hospitalized for acute respiratory symptoms,with HBoV detected from a respiratory sample,using a reverse transcriptase-PCR for 14 respiratory viruses (including respiratory syncytial virus (RSV),influenza virus A and B,human coronavirus OC43,229E,NL-63 and HUK1,adenovirus,rhinovirus,parainfluenza virus 1-3,and human metapneumovirus).Results HBoV was detected alone in 29 (48.3%) patients,while in co-infection with other viruses in 31 patients (51.7%),with a peak between December and *** the 60 patients,34 were bronchiolitis,19 wheezing,3 pneumonia,2 upper respiratory tract infection,and 2 whooping *** children (11.6%) required admission to the paediatric intensive care unit (PICU) for respiratory *** differences was observed in age,family history for atopy and/or asthma,clinical presentations,chest X-ray,or laboratory findings in children with HBoV alone *** viral *** was the most frequently co-detected virus (61.3%).When compared with HBoV detection alone,the co-detection of RSV and HBoV was associated with male sex (P=0.013),younger age (P=0.01),and lower blood neutrophil count (P=0.032).Conclusions HBoV can be detected alone and in co-infection respiratory samples of children with an acute respiratory tract infection.A cause-effect relationship between HBoV and respiratory infection is not clear,so further studies are needed to clarify this point.

关键词： Human bocavirus Pediatrics Respiratory tract infection Viral infection

Common genetic variations in CLOCK transcription factor are associated with nonalcoholic fatty liver disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2007年第31期13卷 4242-4248页

作者： Silvia Sookoian Gustavo Castao carolina Gemma Tomas Fernández Gianotti Carlos Jose Pirola Instituto de Investigaciones Medicas A. Lanari. Universidad de Buenos Aires CONICET Combatiente de Malvinas 3150 1427-Ciudad Autonoma de Buenos Aires Argentina Consejo de Investigación GCBA Buenos Aires Argentina Consejo de Investigación GCBA Buenos Aires Argentina Instituto de Investigaciones Medicas A. Lanari. Universidad de Buenos Aires CONICET Combatiente de Malvinas 3150 1427-Ciudad Autonoma de Buenos Aires Argentina

To investigate the role of gene variants and derived haplotypes of the CLOCK transcription factor in nonalcoholic fatty liver disease （NAFID） and their relation with the disease ***： A total of 136 patients with NAFLD and 64 healthy individuals were studied. Liver biopsy was performed in 91 patients. Six tag SNPs showing a minor allele frequency 〉 10% （rs1554483 C/G; rs11932595 A/G; rs4580704 C/G; rs6843722 A/C; rs6850524 C/G and rs4864548 A/G） encompassing 117 kb of chromosome 4 and representing 115 polymorphic sites （P 〉 0.8） were genotyped. RESULTS： rs11932595 and rs6843722 showed significant associations with NAFLD （empiric P = 0.0449 and 0.023, respectively）. A significant association was also observed between clinical or histologic spectrum of NAFLD and rs1554483 （empiric P = 0.0399）, rs6843722 （empiric P = 0.0229） and rs6850524 （empiric P = 0.00899） and between fibrosis score and rs1554483 （empiric P = 0.02697）, rs6843722 （empiric P = 0.01898） and rs4864548 （empiric P = 0.02697）. Test of haplotypic association showed that CLOCK gene variant haplotypes frequencies in NAFLD individuals significantly differed from those in controls （empiric P = 0.0097）.CONCLUSION： Our study suggests a potential role of the CLOCK polymorphisms and their haplotypes insusceptibility to NAFLD and disease severity.

关键词： Circadian rhythm Circadian Iocomoter outputcycles protein kaput Gene variants Haplotypes Fattyliver Liver disease Obesity Nonalcoholic steatohepatitis

Expression of miR‑138 in cryopreserved bovine sperm is related to their fertility potential

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Animal Science and Biotechnology 2023年第6期14卷 2383-2394页

作者： Albert Salas‑Huetos Jordi Ribas‑Maynou Yentel Mateo‑Otero carolina Tamargo Marc Llavanera Marc Yeste Unit of Cell Biology Department of BiologyFaculty of SciencesUniversity of GironaGirona 17003Spain. Biotechnology of Animal and Human Reproduction(TechnoSperm) Institute of Food and Agricultural TechnologyUniversity of GironaGirona 17003Spain. Department of Nutrition Harvard T.H.Chan School of Public HealthHarvard UniversityBostonMA 02115USA. Consorcio CIBER M.P.Fisiopatologia de la Obesidad y Nutricion(CIBERobn)Instituto de Salud Carlos III(ISCIII)Madrid 28029Spain. Present Address:Unit of Preventive Medicine and Public Health Faculty of Medicine and Health SciencesUniversitat Rovira i VirgiliReus 43201Spain. Department of Animal Selection and Reproduction The Regional Agri-Food Research and Development Service of Asturias(SERIDA)Gijon 33394Spain. Catalan Institution for Research and Advanced Studies(ICREA) Barcelona 08010Spain.

Background MicroRNAs(miRNAs)are small,single-stranded,non-coding RNA molecules of 22–24 nucleotides that regulate gene *** the last decade,miRNAs have been described in sperm of several mammals,including *** is known that miRNAs can act as key gene regulators of early embryogenesis in mice and humans;however,little is known about the content,expression,and function of sperm-borne miRNAs in early bovine *** this study,total sperm RNA was isolated from 29 cryopreserved sperm samples(each coming from a separate bull)using a RNeasy kit and treatment with DNase *** concentration and purity were determined through an Epoch spectrophotometer and an Agilent *** expression of 10 candidate miRNAs in bovine sperm(bta-miR-10a,bta-miR-10b,bta-miR-138,bta-miR-146b,bta-miR-19b,bta-miR-26a,bta-miR-34a,bta-miR-449a,bta-miR-495 and btamiR-7),previously identified in testis and/or epididymis,was evaluated with *** cel-miR-39-3p was used as a spike-in exogenous *** Mann–Whitney tests were run to evaluate which miRNAs were differentially expressed between bulls with high fertility[HF;non-return rates(NRR)ranging from 39.5 to 43.5]and those with subfertility(SF;NRR ranging from 33.3 to 39.3).Several sperm functionality parameters(e.g.,viability,membrane stability or oxygen consumption,among others)were measured by multiplexing flow cytometry and oxygen sensing *** RNA concentration and purity(260/280 nm ratio)(mean±SD)from the 29 samples were 99.3±84.6 ng/μL and 1.97±0.72,*** results confirmed the lack of RNA from somatic *** terms of the presence or absence of miRNAs,and after applying the Livak method,8 out of 10 miRNAs(bta-miR-10b,-138,-146b,-19b,-26a,-449a,-495,-7)were consistently detected in bovine sperm,whereas the other two(bta-miR-10a,and-34a)were ***,the relative expression of one miRNA(bta-miR-138)in sperm was significantly lower in the SF than in the HF gr

关键词： Bovine Fertility miRNAs Sperm

Essential amino acid ratios and mTOR affect lipogenic gene networks and miRNA expression in bovine mammary epithelial cells

在线全文

学校读者我要写书评

暂无评论

Journal of Animal Science and Biotechnology 2016年第4期7卷 612-622页

作者： Shanshan Li Afshin Hosseini Marina Danes carolina Jacometo Jianxin Liu Juan J.Loor Institute of Dairy Science College of Animal SciencesZhejiang University Department of Animal Sciences Mammalian Nutri Physio GenomicsUniversity of Illinois Department of Animal Science University of Lavras NUPEEC Departamento de Clínicas VeterináriaPrograma de Pós-Gradua??o em BiotecnologiaUniversidade Federal de Pelotas

Background： The objective of this study was to study how changing the ratio of Lys to Thr, Lys to His, and Lys to Val affects the expression of lipogenic genes and microRNA （miRNA） in bovine mammary epithelial cells. Results： Triplicate cultures with the respective ＂optimal＂ amino acid （AA） ratio （OPAA = Lys：Met 2.9：1; Thr：Phe 1.05：1; Lys：Thr 1.8：1; Lys：His 2.38：1; Lys：Val 1.23：1） plus rapamycin （OPAARMC; positive control）, OPAA, Lys：Thr 2.1：1 （LT2.1）, Lys：Thr 1.3：1 （LT1.3）, Lys：His 3.05：1 （LH3.0）, or Lys：Val 1.62：1 （LV1.6） were incubated in lactogenic medium for 12 h. The expression of 15 lipogenic genes and 7 miRNA were evaluated. Responses to LT2.1, LT1.3, LH3.0, and LV1.6 relative to the control （OPAARMC） included up-regulated expression ofACSS2, FABP3, ACACA, FASN, SCD, LPIN1, INSIG1, SREBF1, PPARD, and NR1H3 （commonly known as LXR-a）. Furthermore, LV1.6 up-regulated expression of ACSL1, DGAT1, and RXRA and down-regulated PPARG expression. Although no effect of OPAA on expression of PPARG was observed, compared with the control, OPAA up-regulated expression of the PPAR targets ACSS2, FABP3, ACACA, FASN, SCD, LPIN1, INSIG1, and SREBF1. Compared with the control, the expression of the anti-lipogenic MIR27AB was down-regulated by OPAA, LT2.1, LT1.3 and LH3.0. In contrast, compared with the control, the expression of the pro-lipogenic MIR21 was up-regulated by LT2.1, LT1.3, LH3.0, and LV1.6. Conclusions： The observed up-regulation of lipogenic gene networks and the changes in expression of key miRNA involved in the control of lipogenic balance are indicative of a potentially important role of EAA ratios and mTOR signaling in the regulation of milk fat synthesis.

关键词： Amino acids Milk fat synthesis mTOR Nutrigenomics

Exosomes:Small vesicles with big roles in cancer,vaccine development,and therapeutics

在线全文

学校读者我要写书评

暂无评论

Bioactive Materials 2022年第4期7卷 281-294页

作者： Abhimanyu Thakur Diana carolina Parra Pedram Motallebnejad Marcelo Brocchi Huanhuan Joyce Chen Pritzker School of Molecular Engineering The University of ChicagoUnited States Ben May Department for Cancer Research The University of ChicagoUnited States Tropical Disease Laboratory Department of GeneticsEvolutionMicrobiology and ImmunologyInstitute of BiologyUniversity of Campinas(UNICAMP)S˜ao PauloBrazil

Cancer is a deadly disease that is globally and consistently one of the leading causes of mortality every *** the availability of chemotherapy,radiotherapy,immunotherapy,and surgery,a cure for cancer has not been ***,exosomes have gained significant attention due to the therapeutic potential of their various components including proteins,lipids,nucleic acids,miRNAs,and *** constitute a set of tiny extracellular vesicles with an approximate diameter of 30-100 *** are released from different cells and are present in biofluids including blood,cerebrospinal fluid(CSF),and *** perform crucial multifaceted functions in the malignant progression of cancer via autocrine,paracrine,and endocrine *** ability of exosomes to carry different cargoes including drug and molecular information to recipient cells make them a novel tool for cancer *** this review,we discuss the major components of exosomes and their role in cancer *** also review important literature about the potential role of exosomes as vaccines and delivery carriers in the context of cancer therapeutics.

关键词： Cancer Exosome Therapeutics Extracellular vesicles Exosomal vaccine Exosomal delivery system

Determination of gluten immunogenic peptides for the management of the treatment adherence of celiac disease: A systematic review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2021年第37期27卷 6306-6321页

作者： Laura Coto Irati Mendia carolina Sousa Julio César Bai Angel Cebolla Research and Development BiomedalCamas 41900SevilleSpain Human Nutrition and Food Science Doctoral Program University of GranadaGranada 18011Spain Molecular Biology Biomedicine and Clinical Research Doctoral ProgramUniversity of SevilleSeville 41012Spain Department of Microbiology and Parasitology University of SevilleSeville 41013Spain Department of Gastroenterology Dr.Carlos Bonorino Udaondo Gastroenterology HospitalBuenos Aires 1264Argentina Research Institutes Universidad del SalvadorBuenos Aires 1050Argentina

BACKGROUND Gluten is a complex mixture of proteins with immunogenic peptide sequences triggering the autoimmune activity in patients with celiac disease(CeD).Gluten immunogenic peptides(GIP)are resistant to gastrointestinal digestion and are then excreted via the stool and *** common detection methods applied in the follow-up visits for CeD patients such as serology tests,dietetic interviews,questionnaires,and duodenal biopsy have been proved to be inefficient,invasive,or inaccurate for evaluating gluten-free diet(GFD)*** of excreted GIP in stool and urine has been developed as a non-invasive,direct,and specific test for GFD *** To summarize published literature about the clinical utility of GIP determination in comparison to the tools employed for GFD *** PubMed and Web of Science searches were performed using the keywords“gluten immunogenic peptides”or“gluten immunogenic peptide”and a combination of the previous terms with“feces”,“stools”,“urine”,“celiac disease”,“gluten-free diet”,and“adherence”to identify relevant clinical studies published in English and Spanish between 2012 to January *** lists from the articles were reviewed to identify additional pertinent *** articles and abstracts reporting the clinical use of GIP determination in stool and/or urine for the follow-up of patients with CeD in comparison with other tools in use were *** reports,commentaries,reviews,conference papers,letters,and publications that did not focus on the aims of this review were *** Total of 15 publications were found that involved the use of GIP determination in stool and/or urine to monitor the adherence to the GFD in comparison to other *** included both children and adults diagnosed with CeD and healthy ***,these preliminary studies indicated that this novel technique was highly sensitive for the detection of GFD transgressions and therefore could fac

关键词： Celiac disease Gluten-free diet Gluten immunogenic peptides Immunoassays Stool Urine