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Associated Factors of Dental Caries among Intellectually Disabled Persons in Specialized Centers of Ouagadougou

Open Journal of Epidemiology 2024年第2期14卷 297-311页

作者： Jocelyne Valerie Gare Filwende Dan Kientega Ouedraogo carole Nathaie Tenin Ouattara Seydou Kabore Wendpoulomde Aime Désire Nicolas Meda Training and Research Unit in Health Sciences Department of Public Health Joseph Ki Zerbo University Ouagadougou Burkina Faso Training and Research Unit in Health Sciences Department of Dental Surgery Joseph Ki Zerbo University Ouagadougou Burkina Faso

Introduction: Several studies have reported a high prevalence of dental caries among the people with intellectual disabilities. In order to identify the sociodemographic, clinical and behavioral factors associated with it, we conducted a study in specialized centers welcoming subjects with intellectual disabilities in Ouagadougou (Burkina Faso). Objectives: The objective of this study was to identify the factors associated with it among intellectually disabled in the specialized centers of Ouagadougou. Methods: The study was cross-sectional analytical. The survey took place between November 2020 and January 2021 among people with intellectual disabilities in reception centers receiving a grant from the Ministry of Women, National Solidarity, Family and Humanitarian Action. Data collection was done with a questionnaire adapted from the World Health Organization (WHO) and dental caries was recorded according to WHO criteria in decayed, missing or filled teeth generating a DMF index. Logistic regression was used to identify factors associated with the presence of dental caries. Results: A total of 193 participants were included in the study with an average age of 12.4 years ± 7.9. The overall prevalence of caries measured with the DMF index was 58.6% 95% CI [51.2 - 65.8]. It was significantly associated with female gender (OR = 4.2;95% CI [1.4 - 12.5], p = 0,01), the clinical form of mental illness (epilepsy OR = 3.8 95%;CI [1.2 - 12.7], p = 0,02, trisomy OR = 5.0;95% CI [1.1 - 22.9], p = 0,03, motor autonomy OR = 0.2 95%;CI [0.1 - 0.7], p = 0,01) and at use of toothpaste OR = 9.33;95% CI [1.05 - 82.7], p = 0,04. Conclusion: Dental caries remains a very present pathology in most people living with an intellectual disability. Also, it is necessary to put in place prevention strategies to reduce its prevalence and improve access to oral care for these people.

关键词： Dental Caries Mental Disability Intellectual Disability Associated Factors Ouagadougou

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现代护理知识测验

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国际护理学杂志 1985年第3期6卷 160-161+130页

作者： R carole King 何风增

1.血清中含量最多的免疫球蛋白(Ig)是: ***。***。***。***。 2.机体表面能防御微生物侵入的(Ig)是: ***。***。***。***。 3.产生严重反应的免疫机制是: a.血清病。b.过敏性。c.特异性变态反应。d.预防注射。 4.过敏症体征包括: a.平... 详细信息

1.血清中含量最多的免疫球蛋白(Ig)是: ***。***。***。***。 2.机体表面能防御微生物侵入的(Ig)是: ***。***。***。***。 3.产生严重反应的免疫机制是: a.血清病。b.过敏性。c.特异性变态反应。d.预防注射。 4.过敏症体征包括: a.平滑肌广泛收缩。b.支气管痉挛。c.低血压。d.这些都有。

关键词：呼吸道分泌物患者手术低血压护理措施人工免疫人工获得性免疫抗原血清病变态反应病医嘱下肢四肢现病史

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掀起一场教与学的革命

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国外职业教育 2006年第2期 35-37页

作者： carole Eaton（美）沈雅婕（译）

俄亥俄州一个差等小学是如何使其三年级的阅读测试通过率飙升了惊人的124％。

关键词：美国教学改革阅读测试俄亥俄州三年级小学教育技术

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Increased circulating rather than spinal cytokines accompany chronic pain behaviors in experimental bone cancer and arthritis

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Neuroimmunology and Neuroinflammation 2014年第1期1卷 153-160页

作者： Line Pourtau Amarins Nieske Heeringa carole Rovère Agnès Aubert Jean-Louis Nahon Sylvain Miraux Jan Pieter Konsman CNRS PsychoNeuroImmunologieNutrition et GénétiqueUMR 522633076 BordeauxFrance Univ.Bordeaux PsyNuGenUMR 522633076 BordeauxFrance CNRS Institut de Pharmacologie Moléculaire et CellulaireUMR 727506560 ValbonneFrance Univ.Nice Sophia Antipolis 06130 NiceFrance CNRS Résonance Magnétique des Systèmes BiologiquesUMR 553633076 BordeauxFrance Univ.Bordeaux RMSBUMR 553633076 BordeauxFrance

Aim:Peripheral cytokines contribute to arthritis and bone cancer pain through sensory nerve ***,increased spinal cytokine and glial filament expression,coined neuroinflammation,has also been proposed to play a part in chronic ***,spinal cord,dorsal root ganglia and circulating cytokines were compared in murine arthritis and bone cancer models in relationship to behavioral signs of ***:Exploratory behaviors were studied after intra-articular complete Freund’s adjuvant or bone intramedullary sarcoma cell *** tissue and blood cytokine expression were determined by real-time polymerase chain reaction(PCR)and multiplex immunoassays,***:PCR analysis did not reveal any hallmark of spinal neuroinflammation in spontaneously-behaving mice with cartilage or bone ***,imposed paw stimulation during joint inflammation increased spinal interleukin-1β(IL-1β)*** paw guarding during rearing was displayed by animals with joint inflammation and bone destruction and was accompanied by increased circulating IL-6 and monocyte chemoattractant protein-1,*** addition,dorsal root ganglia were found to constitutively express receptors for this chemotactic ***:Our findings indicate that spinal neuroinflammation is not a necessary condition for chronic pain and suggest that circulating cytokine action in dorsal root ganglia may contribute to experimental joint inflammation and bone cancer pain.

关键词： itis bone cancer CCL2 cytokines dorsal root ganglia pain spinal cord

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Physical Characteristics and the Effect of Boiling and Fermentation on the Nutritional Value of <i>Telfairia occidentalis</i>Seeds

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Journal of Agricultural Chemistry and Environment 2021年第4期10卷 389-401页

作者： Mercy Bih Loh Achu Ruth Viviane Djuikwo Stéphane Ghomsi Tamo Christiane Laure Maptouom Fotso Michelle carole Djouhou Fowe Elie Fokou Laboratory for Food Science and Metabolism Department of Biochemistry Faculty of Science University of Yaoundé I Yaoundé Cameroon

This work evaluates some physical parameters (the weight, length, diameter of fruits and seeds, number of seeds per fruit) and the effect of boiling and fermentation on the nutritional value of Telfairia occidentalis (fluted pumpkin) seeds. Firstly, a survey was done in the city of Yaounde on the different treatments applied to the seeds before cooking. From the results of the survey, the seeds were divided into three groups: raw, boiled and fermented. The moisture, lipid, protein, fibre, carbohydrate and ash contents were analysed using AOAC methods and minerals by atomic absorption spectrophotometry. The results showed that T. occidentalis fruit averagely weighed 6.35 kg and contained about 90 seeds. The decorticated seeds had an ovoid shape, 3.70 cm long and weighed 8.91 g. Boiling led to an increase in lipid (16.29% - 31.44%) and carbohydrate (19.20% - 21.8%) but a decrease in protein (54.06% - 34.17%) contents. Fermentation increased the crude fibre (0.70% - 1.1%) but decreased the ash content (4.07% - 3.14% DM). Boiled seeds had higher calcium, magnesium, potassium and sodium, while fermented seeds had higher zinc levels. Boiling proved better in preserving most of the seed nutrients. These seeds could be used to prevent some mineral deficiencies and their high proteins suggest their potential for the formulation of infant foods.

关键词： Physical Parameters Nutritional Composition Boiling Fermentation Telfairia occidentalis Seeds

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Diversity, Chemical Compositions and Beneficial Effects of Some Spices and Aromatic Leaves Consumed in Benin and in the World: Critical Review

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American Journal of Plant Sciences 2023年第5期14卷 569-598页

作者： carole Vikou Josiane Semassa Zoriţa Diaconeasa Gautier Roko Majoie Tohoyessou Durand Dah-Nouvlessounon Haziz Sina Andreea Stanilă Lamine Baba-Moussa Laboratory of Biology and Molecular Typing in Microbiology Faculty of Science and Technology University of Abomey-Calavi Abomey-Calavi Benin Republic Faculty of Food Science and Technology University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca Cluj-Napoca Romania

Spices and aromatic plants are products of plant origin used in food. They are used for the preparation of remedies, for seasoning dishes or for preserving food. This review takes stock of the diversity of spices and aromatic herbs, the chemical composition, the different properties and forms of use of six spices and aromatic herbs commonly used in Benin and around the world. These are Zingiber officinalis (ginger), Curcuma longa (curcuma), Syzygium aromaticum (clove) and three aromatic herbs Petroselinum crispum (parsley), Rosmarinus officinalis (rosemary), and Laurus nobilis (laurel). The methodology used is that of documentary research oriented towards the consultation of previous scientific documents that have highlighted the different pharmacological activities of the different species of spices and aromatic plants targeted. It is important to note that more than twenty plant species are used as spices and aromatic plants in Benin and around the world. Chemically, these different spices and aromatic herbs contain certain secondary metabolites such as flavonoids, tannins, coumarins, alkaloids, steroids, terpenes, saponins, and polyphenols. This diversity of secondary metabolites alone or in a possible synergy may be responsible for many beneficial properties attributed to spices and aromatic herbs.

关键词： Spices Aromatic Leaves Pharmacological Effects Humans

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跨越边界：卡洛尔·波伊斯·戴维斯访谈录（英文）

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外国文学研究 2019年第6期41卷 1-15页

作者：郑丽卡洛尔·波伊斯·戴维斯北京航空航天大学外国语学院美国康纳尔大学英语和非洲文学研究中心

卡洛尔·波伊斯·戴维斯是美国康纳尔大学英语和非洲文学研究教授,因其作为学者、教育家及社会活动家所具有的世界影响力,于2017年荣获纽约州非洲研究协会颁发的杰出非洲研究者奖与弗朗茨·法农终身成就奖。用加勒比哲学协会主席尼尔·... 详细信息

卡洛尔·波伊斯·戴维斯是美国康纳尔大学英语和非洲文学研究教授,因其作为学者、教育家及社会活动家所具有的世界影响力,于2017年荣获纽约州非洲研究协会颁发的杰出非洲研究者奖与弗朗茨·法农终身成就奖。用加勒比哲学协会主席尼尔·罗伯茨的话来说:"卡洛尔·波伊斯·戴维斯是加勒比思想和非洲流散研究领域的巨人。"事实上,谈及离散、去殖民化、黑人女性的历史和哲学、黑人激进传统等领域的研究,戴维斯不可或缺。目前她已发表多部著作,包括获得奖项的《黑人女性、书写与身份:主题的迁移》(1994),自编或与人合编了几部有关非洲离散文学的论文集。受《外国文学研究》委托,郑丽对戴维斯进行了专访,就一系列问题,如黑人女性写作和身份、主体迁移、非洲流散的时空架构、非洲书写及与其他少数族裔书写的异同、全球化背景下女性的世界主义视野和身份认同等等进行了热烈探讨。戴维斯分享了她有关当今世界女性如何充分实现自我和发挥潜力的观点。如何平衡民族主义与世界主义,不仅是非洲人民,而且是我们所有人,无论什么民族、性别或国籍,必须面对的问题。

关键词：卡洛尔·波伊斯·戴维斯流散非洲女性主义迁移主体跨越边界世界主义

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Bioreactivity of Stent Material: <i>In Vitro</i>Impact of New Twinning-Induced Plasticity Steel on Platelet Activation

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Journal of Biomaterials and Nanobiotechnology 2019年第4期10卷 175-189页

作者： carole Verhaegen Sophie Lepropre Marie Octave Davide Brusa Luc Bertrand Christophe Beauloye Pascal J. Jacques Joelle Kefer Sandrine Horman Pôle de Recherche Cardiovasculaire Université catholique de Louvain (UCLouvain) Brussels Belgium Plateforme de Cytométrie de Flux Université catholique de Louvain (UCLouvain) Brussels Belgium Division of Cardiology Cliniques Universitaires Saint-Luc Université catholique de Louvain (UCLouvain) Brussels Belgium Department of Materials and Process Engineering Institute of Mechanics Materials and Civil Engineering Université catholique de Louvain (UCLouvain) Brussels Belgium

A current challenge concerns developing new bioresorbable stents that combine optimal mechanical properties and biodegradation rates with limited thrombogenicity. In this context, twinning-induced plasticity (TWIP) steels are good material candidates. In this work, the hemocompatibility of a new TWIP steel was studied in vitro via hemolysis and platelet activation assessments. Cobalt chromium (CoCr) L605 alloy, pure iron (Fe), and magnesium (Mg) WE43 alloy were similarly studied for comparison. No hemolysis was induced by TWIP steel, pure Fe, or L605 alloy. Moreover, L605 alloy did not affect CD62P exposure, αIIbβ3 activation at the platelet surface, or phosphorylation of protein kinase C (PKC) substrates upon thrombin stimulation. In contrast, TWIP steel and pure Fe significantly decreased platelet response to the agonist. Given that similar inhibitory effects were obtained when using a conditioned medium previously incubated with TWIP steel, we postulated TWIP steel corrosion to be likely to release components counteracting platelet activation. We showed that the main ion form present in the conditioned medium is Fe3+. In conclusion, TWIP steel resorbable scaffold displays anti-thrombogenic properties in vitro, which suggests that it could be a promising platform for next-generation stent technologies.

关键词： Stent TWIP Steel Platelet Biomaterial Hemocompatibility

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Delayed treatment of secondary degeneration following acute optic nerve transection using a combination of ion channel inhibitors

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Neural Regeneration Research 2017年第2期12卷 307-316页

作者： Nathanael J.Yates Marcus K.Giacci Ryan L. O'Hare Doig Wissam Chiha Bethany E. Ashworth Jade Kenna carole A. Bartlett Melinda Fitzgerald Department of Experimental and Regenerative Neurosciences School of Animal Biology The University of Western Australia Crawley Western Australia Australia Department of Experimental and Regenerative Neurosciences School of Anatomy Physiology and Human Biology The University of Western Australia Crawley Western Australia Australia

Studies have shown that a combined application of several ion channel inhibitors immediately after central nervous system injury can inhibit secondary degeneration. However, for clinical use, it is necessary to determine how long after injury the combined treatment of several ion channel inhibitors can be delayed and efficacy maintained. In this study, we delivered Ca^2＋ entry-inhibiting P2X7 receptor antagonist oxidized-ATP and AMPA receptor antagonist YM872 to the optic nerve injury site via an iPRECIO-@ pump immediately, 6 hours, 24 hours and 7 days after partial optic nerve transection surgery. In addition, all of the ion channel inhibitor treated rats were administered with calcium channel antagonist lomerizine hydrochloride. It is important to note that as a result of implantation of the particular pumps required for programmable delivery of therapeutics directly to the injury site, seromas occurred in a significant proportion of animals, indicating infection around the pumps in these animals. Improvements in visual function were observed only when treatment was delayed by 6 hours; phosphorylated Tau was reduced when treatment was delayed by 24 hours or 7 days. Improvements in structure of node/paranode of Ranvier and reductions in oxidative stress indicators were also only observed when treatment was delayed for 6 hours, 24 hours, or 7 days. Benefits of ion channel inhibitors were only observed with time-delayed treatment, suggesting that delayed therapy of Ca^2＋ ion channel inhibitors produces better neuroprotective effects on secondary degeneration, at least in the presence of seromas.

关键词： nerve regeneration optic nerve injury neurotrauma secondary degeneration seromas calcium channel inhibitor node of Ranvier Tau phosphorylation lipid peroxidation oxidative stress neural regeneration

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Associated Factors to Immunization Timeliness and Completion in Preterm and Low Birth Weight Infants at Essos Hospital Center Yaounde

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Open Journal of Pediatrics 2021年第1期11卷 9-18页

作者： Marie Kouya Annie carole Nga Motaze Jeannette Epée Ngoue Arsène Brunelle Sandie Paul Olivier Koki Ndombo Anne Esther Njom Nlend Higher Institute of Medical Technology Nkolondom University of Douala Douala Cameroon Essos Hospital Centre Unit of Neonatology Yaoundé Cameroon Faculty of Medicine and Biomedical Sciences University of Yaounde 1 Yaoundé Cameroon Pan African University of Nairobi Nairobi Kenya

Introduction: Vaccination is very often delayed in premature and low birth weight infants. However, timely vaccination is even more important in this population because of their increased susceptibility to infection. Objective: To assess immunization practice and factors associated with vaccine promptness and completeness in former preterm and low-birth-weight infants. Methods: We conducted a retrospective analytical cross-sectional study (January 2017 to February 2019). Main Measurement: Promptness and completeness at each contact, Statistical analysis was performed using R software version 3.6.2, logistic regression was used to estimate the Odds Ratio (OR) and their 95% Confidence Interval (CI). Results: We recruited 310 children aged 12 to 36 months born before 37 weeks with low birth weight, 163 (52.6%) of whom were female. Two hundred and fifty-three had received the vaccines at the indicated age, with promptness rate of 81.6%, and 97.7% had completed routine immunization at 9 months. The mean age at vaccination initiation was 6 days ± Prematurity Low Birth Weight Immunization Timeliness Completion

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