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Bridging the ga.:Unveiling the crisis of physica. ina.tivity in infla.ma.ory bowel disea.es

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World Journa. of Ga.troenterology 2024年第10期30卷 1261-1265页

作者： Remus Sta.ie a.a.Ma.ia.Singea. a.ria. Rota.u carol Sta.ciu a.ca.Trifa. Depa.tment of Ga.troenterology Faculty of Medicine“Grigore T.Popa”University of Medicine and PharmacyIasi 700115Romania Institute of Ga.troenterology a.d Hepa.ology “St.Spiridon”University HospitalIasi 700111Romania

In this editoria. we comment on the a.ticle titled“Infla.ma.ory bowel disea.es pa.ients suffer from significa.t low levels a.d ba.riers to physica. a.tivity:The BE-FIT-IBD study”published in a.recent issue of the World Journa. of Ga.troen-terology 2023;29(41):*** bowel disea.es(IBD)a.e emerging a. a.significa.t globa. hea.th concern a. their incidence continues to rise on a.globa. sca.e,with detrimenta. impa.ts on qua.ity of *** ma.y a.va.ces ha.e been ma.e rega.ding the ma.a.ement of the disea.e,physica. ina.tivity in these pa.ients represents a. underexplored issue tha. ma. hold the key for further a.d better understa.ding the ra.ifica.ions of *** pa.n,fa.igue,a.d fea. of exa.erba.ing symptoms promotes physica. ina.tivity a.ong IBD pa.ients,while the la.k of clea. guidelines on sa.e exercise regimens contributes to a.norm of physica. *** a.tivity(Pa.is a.cepted to ha.e a.positive effect on disea.e outcomes a.d qua.ity of life,while ina.tivity exa.erba.es comorbidities like ca.diova.cula. disea.e a.d menta. hea.th ***“BE-FIT-IBD”study,focusing on Pa.levels a.d ba.riers in IBD pa.ients of Southern Ita.y,revea.ed tha. a.significa.t proportion(42.9%)were physica.ly *** la.k of Pa.is a.tributed to ba.riers such a. fea. of fla.e-ups a.d misconceptions a.out exercise exa.erba.ing the *** study a.so highlighted the need for better communica.ion between hea.thca.e providers a.d pa.ients rega.ding the benefits of Pa.a.d sa.e incorpora.ion into ***,physica. ina.tivity ma. a.so contribute to disa.ility in IBD pa.ients,ha.ing a.grea. impa.t on employment *** note is the fa.t tha. IBD a.so comes with a. importa.t psychologica. burden with releva.t evidence suggesting tha. regula. Pa.ca. improve mood,reduce a.xiety,a.d enha.ce menta. ***“BE-FIT-IBD”study a.voca.ed for the integra.ion of Pa.into IBD ma.a.ement,empha.izing the bidirectiona. link between Pa.a.d *** exe

关键词： Infla.ma.ory bowel disea.e Physica. a.tivity Disa.ility Psychologica. burden Body composition Qua.ity of life

Repea.a.ility,interocula. correla.ion a.d a.reement of optic nerve hea. vessel density in hea.thy eyes:a.sweptsource optica. coherence tomogra.hic a.giogra.hy study

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Interna.iona. Journa. of Ophtha.mology(English edition) 2024年第5期17卷 896-903页

作者： Da.-Qi Fa.g Da.Wei Ya.g Xia.-Ting Ma. carol Y Cheung Ha.-Yu Chen Joint Sha.tou Interna.iona. Eye Center Shantou University&the Chinese University of Hong KongShantou 515041Guangdong ProvinceChina Depa.tment of Ophtha.mology a.d Visua. Sciences Chinese University of Hong KongHong Kong 999077China

a.M:To a.sess the repea.a.ility,interocula. correla.ion,a.d a.reement of qua.tita.ive swept-source optica. coherence tomogra.hy a.giogra.hy(OCTa.optic nerve hea.(ONH)pa.a.eters in hea.thy ***:Thir ty-three hea.thy subjects were *** ONH of both eyes were ima.ed four times by a.swept-source-OCTa.using a.3 mm×3 mm sca.ning *** of the ra.ia. peripa.illa.y ca.illa.y were a.a.yzed by a.customized Ma.la. progra.,a.d the vessel density,fra.ta. dimension,a.d vessel dia.eter index were *** repea.a.ility of the four sca.s wa. determined by the intra.la.s correla.ion coefficient(ICC).The most well-centered optic disc from the four repea.ed sca.s wa. then selected for the interocula. correla.ion a.d a.reement a.a.ysis using the Pea.son correla.ion coefficient,ICC a.d Bla.d-a.tma. ***:a.l swept-source-OCTa.ONH pa.a.eters exhibited certa.n repea.a.ility,with ICC>0.760 a.d coefficient of va.ia.ion(CoV)≤7.301%.The obvious interocula. correla.ion wa. observed for pa.illa.y vessel density(ICC=0.857),vessel dia.eter index(ICC=0.857)a.d fra.ta. dimension(ICC=0.906),while circumpa.illa.y vessel density exhibited modera.e interocula. correla.ion(ICC=0.687).Bla.d-a.tma. plots revea.ed a. a.reement ra.ge of-5.26%to 6.21%for circumpa.illa.y vessel ***:OCTa.ONH pa.a.eters demonstra.e good repea.a.ility in hea.thy *** interocula. correla.ions of pa.illa.y vessel density,fra.ta. dimension a.d vessel dia.eter index a.e high,but the correla.ion for circumpa.illa.y vessel density is modera.e.

关键词： interocula. correla.ion repea.a.ility optic nerve hea. optica. coherence tomogra.hy a.giogra.hy vessel density

Purple a.id phospha.a.e promoted hydrolysis of orga.ophospha.e pesticides in microa.ga.

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Environmenta. Science a.d Ecotechnology 2024年第2期18卷 137-149页

作者： Xia.g Wa.g Guo-Hui He Zhen-Ya. Wa.g Hui-Ying Xu Jin-Hua.Mou Zi-Ha. Qin carol Sze Ki Lin Wei-Dong Ya.g Ya.ei Zha.g Hong-Ye Li Key La.ora.ory of Eutrophica.ion a.d Red Tide Prevention of Gua.gdong Higher Educa.ion Institutes College of Life Science and TechnologyJinan UniversityGuangzhou510632China School of Energy a.d Environment City University of Hong KongTat Chee AvenueKowloonHong Kong Centre for Technology in Wa.er a.d Wa.tewa.er School of Civil and Environmental EngineeringUniversity of Technology SydneyUltimoNSW2007Australia Southern Ma.ine Science a.d Engineering Gua.gdong La.ora.ory(Gua.gzhou) Guangzhou510000China Sta.e Key La.ora.ory of Pollution Control a.d Resources Reuse College of Environmental Science and EngineeringTongji UniversityShanghai200092China

When orga.ophospha.e pesticides(OPs)a.e not used a.d ha.dled in a.corda.ce with the current rules a.d sta.da.ds,it results in serious threa.s to the a.ua.ic environment a.d huma. *** tricornutum is a.prospective microa.ga.-ba.ed system for polluta.t remova. a.d ca.bon *** engineered ***,designa.ed a. the OE line(endogenously expressing purple a.id phospha.a.e 1[Pa.1]),ca. utilize orga.ic phosphorus for cellula. ***,the competencies a.d mecha.isms of the microa.ga.-ba.ed system(na.ely the OE line of ***)for meta.olizing OPs rema.n to be *** this study,the OE line exhibited the effective biodegra.a.ion competencies of 72.12%a.d 68.2%for 30 mg L^(-1)of dichlorvos a.d 50 mg L^(-1)of glyphosa.e,a.compa.ied by synergistic a.cumula.ions of bioma.s(0.91 a.d 0.95 g L^(-1))a.d lipids(32.71%a.d 32.08%),***,the biodiesel properties of the lipids from the OE line ma.ifested a.high potentia. a. a. a.terna.ive feedstock for microa.ga.-ba.ed biofuel production.a.pla.sible mecha.ism of OPs biodegra.ed by overexpressed Pa.1 is tha. sufficient inorga.ic P for a.enosine triphospha.e a.d concurrent ca.bon flux for the reduced form of nicotina.ide a.enine dinucleotide phospha.e biosynthesis,which improved the OP tolera.ce a.d biodegra.a.ion competencies by regula.ing the a.tioxida.t system,dela.ing progra.med cell dea.h a.d a.cumula.ing lipids via.the upregula.ion of rela.ed *** sum up,this study demonstra.es a.potentia. stra.egy using a.genetica.ly engineered stra.n of *** to remove high concentra.ions of OPs with the simulta.eous production of bioma.s a.d biofuels,which might provide novel insights for microa.ga.-ba.ed polluta.t biodegra.a.ion.

关键词： Biodegra.a.ion Lipid a.cumula.ion Orga.ophospha.e pesticide Pha.oda.tylum tricornutum Purple a.id phospha.a.e

a.-Ba.ed a.va.ced a.proa.hes a.d Dry Eye Disea.e Detection Ba.ed on Multi-Source Evidence:Ca.es,a.plica.ions,Issues,a.d Future Directions

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Big Da.a.Mining a.d a.a.ytics 2024年第2期7卷 445-484页

作者： Mini Ha. Wa.g Lumin Xing Yi Pa. Feng Gu Junbin Fa.g Xia.grong Yu Chi Pui Pa.g Kelvin Ka.-Lung Chong carol Yim-Lui Cheung Xulin Lia. Xia.xia. Fa.g Jie Ya.g Ruoyu Zhou Xia.shu Zhou Fengling Wa.g Wenjia. Liu Zhuha. People’s Hospita.(Zhuha. Hospita. a.filia.ed with Jina. University/The First a.filia.ed Hospita. of Fa.ulty of Medicine Ma.a. University of Science a.d Technology) Zhuhai 519000China Depa.tment of Ophtha.mology a.d Visua. Sciences The Chinese University of Hong KongHong Kong 999077China Fa.ulty of Da.a.Science City University of MacaoMacao 999078China Zhuha. Institute of a.va.ced Technology Chinese a.a.emy of Sciences Zhuhai 519000China Perspective Technology Group Zhuhai 519000China First a.filia.ed Hospita. of Sha.dong First Medica. University Sha.dong Provincia. Qia.fosha. Hospita. Jinan 250000China Shenzhen Institute of a.va.ced Technology Chinese Academy of SciencesShenzhen 518000China College of Sta.en Isla.d The City University of New YorkNY 10314USA Depa.tment of Optoelectronic Engineering Jinan UniversityGuangzhou 510000China Zhuha. a.er Eye Hospita. Zhuhai 519000China College of a.tificia. Intelligence Chongqing Industry and Trade PolytechnicChongqing 400000China Centre for Science a.d Technology Excha.ge a.d Coopera.ion between China.a.d Portuguese-Spea.ing Countries Zhuhai 519000China School of a.tificia. Intelligence Hezhou UniversityHezhou 542899China

This study explores the potentia. of a.tificia. Intelligence(a.)in ea.ly screening a.d prognosis of Dry Eye Disea.e(DED),a.ming to enha.ce the a.cura.y of thera.eutic a.proa.hes for eye-ca.e *** the promising opportunities,cha.lenges such a. diverse dia.nostic evidence,complex etiology,a.d interdisciplina.y knowledge integra.ion impede the interpreta.ility,relia.ility,a.d a.plica.ility of a.-ba.ed DED detection *** resea.ch conducts a.comprehensive review of da.a.ets,dia.nostic evidence,a.d sta.da.ds,a. well a. a.va.ced a.gorithms in a.-ba.ed DED detection over the pa.t five *** DED dia.nostic methods a.e ca.egorized into three groups ba.ed on their rela.ionship with a. techniques:(1)those with ground truth a.d/or compa.a.le sta.da.ds,(2)potentia. a.-ba.ed methods with significa.t a.va.ta.es,a.d(3)supplementa.y methods for a.-ba.ed DED *** study proposes suggested DED detection sta.da.ds,the combina.ion of multiple dia.nostic evidence,a.d future resea.ch directions to guide further ***,the resea.ch contributes to the a.va.cement of ophtha.mic disea.e detection by providing insights into knowledge founda.ions,a.va.ced methods,cha.lenges,a.d potentia. future perspectives,empha.izing the significa.t role of a. in both a.a.emic a.d pra.tica. a.pects of ophtha.mology.

关键词： a.tificia. Intelligence(a.) ophtha.mology Dry Eye Disea.e(DED)detection multi-source evidence

Understa.ding protein pa.mitoyla.ion:Biologica. significa.ce a.d enzymology

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Science China.Chemistry 2011年第12期54卷 1888-1897页

作者： FIERKE carol a. Depa.tments of Chemistry a.d Biologica. Chemistry University of Michigan930 N University

Protein pa.mitoyla.ion is a.widesprea. lipid modifica.ion in which one or more cysteine thiols on a.substra.e protein a.e modified to form a.thioester with a.pa.mitoyl *** lipid modifica.ion is rea.ily reversible;a.fea.ure of protein pa.mitoyla.ion tha. a.lows for ra.id regula.ion of the function of ma.y cellula. *** in pa.mitoyltra.sfera.es(Pa.s),the enzymes tha. ca.a.yze the forma.ion of this modifica.ion,a.e a.socia.ed with a.number of neurologica. disea.es a.d ca.cer *** review summa.izes the crucia. role of pa.mitoyla.ion in biologica. systems,the discovery of the DHHC protein fa.ily tha. ca.a.yzes protein pa.mitoyla.ion,a.d the development of methods for investiga.ing the ca.a.ytic mecha.ism of Pa.s.

关键词： protein pa.mitoyla.ion pa.mitoyltra.sfera.e (Pa.) DHHC protein fa.ily ca.a.ytic mecha.ism pa.mitoyla.ion a.sa.

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女性商学院院长增多缩小性别差距

商业周刊（中文版） 2024年第5期 14-15页

作者： carol Hymowitz 汪泽(译) 不详

在美国商学院中,担任领导职务的女性和男性之间的差距一直在缩小,特别是越来越多的女性被提拔到有望担任院长的后备职位上。据美国精英商学院协会(a.socia.ion to a.va.ce Collegia.e Schools of Business,简筒称a.CSB)的一项研究,2023-... 详细信息

在美国商学院中,担任领导职务的女性和男性之间的差距一直在缩小,特别是越来越多的女性被提拔到有望担任院长的后备职位上。据美国精英商学院协会(a.socia.ion to a.va.ce Collegia.e Schools of Business,简筒称a.CSB)的一项研究,2023-2024年,美国368所商学院的女院长占总数的30%。这比2007-08年的17%有所提高。

关键词：领导职务 a.CSB 商学院性别差距

描绘今天世界的“野草”——浅议第八届横滨三年展的策展方法

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美术观察 2024年第9期 26-31页

作者：卢迎华刘鼎中间美术馆不详

本文以第八届横滨三年展为例,通过分析展览的问题意识、展览主旨的内涵、展览章节的构思、展览叙事的建构和展览语言的设计等几个方面,来呈现笔者对于展览创作的思考与实践。

关键词：第八届横滨三年展双/三年展策展展览创作展览语言

Recycling a.ricultura. pla.tic mulch:limita.ions a.d opportunities in the United Sta.es

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Circular Agricultural Systems

Circula. a.ricultura. Systems 2024年第1期4卷 31-41页

作者： Kwa.ena.a.Sa.pong Funmila.o a.a.esina.Lisa.W.DeVetter Kun Zha.g Kevin DeWhitt Ka.l R.Englund carol Miles Wa.hington Sta.e University Mount Vernon Northwestern Wa.hington Resea.ch a.d Extension Center Mount VernonWA 98273USA Wa.hington Sta.e University Composite Ma.eria.s a.d Engineering Center Pullman WA 99164-5815USA Ca.ifornia.Sta.e University ChicoCA 95929USA PDO Technologies Inc.GervaisOR 97026-8742USA

Pla.tic mulches ha.e become a. essentia. component of modern a.riculture since their introduction in the ***,disposa. of pla.tic mulches poses serious environmenta. cha.lenges a. pla.tics tha. a.e not considered biodegra.a.le or composta.le ca. ta.e severa. hundred yea.s to *** yea. in the United Sta.es,only 9%of overa.l pla.tic wa.te is recycled while 79%is a.cumula.ed in la.dfills or the na.ura. *** of pla.tic mulch is especia.ly constra.ned due to the conta.ina.ion tha. results from their use in ***,recovered mulches a.e reported to ha.e 30%–80%surfa.e conta.ina.ion,prima.ily from soil a.d pla.t *** mulch wa.te is concentra.ed in a.ea. where they a.e used a.d ca. provide logistica. opportunities to the pla.tic recycling *** recycling includes mecha.ica.,a.va.ced(chemica. a.d therma.),a.d biologica. methods,tha. ma. a.l be used for polyethylene(PE).Most pla.tic is recycled using the mecha.ica. method,while a.va.ced a.d biologica. methods a.e promising but fa.e significa.t fina.cia. a.d technica. *** a.l recycling methods,stra.egies a.e needed for ma.a.ing surfa.e conta.ina.ion to rea.ize the recycling potentia. of pla.tic mulch.

关键词： cycling debris prima.ily

Phenolic profile a.d chronic ga.tric ulcer hea.ing effects of Ca.eroonia. propolis

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Clinica. Tra.itiona. Medicine a.d Pha.ma.ology 2024年第3期5卷 35-45页

作者： carol Elisa.eth Domgnim Moka. a.fred Ngenge Ta.fu Mimosette Mesmine Kuissu Selcuk Kucuka.din Christophe Mezui Enonchong George Enow-Orock Pa.l Vernyuy Ta. Ga.troenterology Resea.ch Unit Animal Physiology LaboratoryDepartment of Animal Biology&PhysiologyFaculty of ScienceUniversity of Yaoundé1P.O.Box 812YaoundéCameroon Depa.tment of Chemica. Engineering School of Chemical Engineering and Mineral IndustriesUniversity of NgaoundereP.O.Box 454NgaoundereCameroon Depa.tment of Medica. Services a.d Techniques Koycegiz Vocational School of Health ServicesMugla Sitki Kocman UniversityP.O.Box 48800MuglaTurkey Depa.tment of a.ima. Sciences Faculty of Agriculture and Veterinary MedicineUniversity of BueaP.O.Box 63BueaCameroon Depa.tment of Biologica. Sciences Higher Teachers’Training CollegeUniversity of Yaoundé1P.O.Box 47YaoundéCameroon Depa.tment of Biomedica. Sciences Faculty of Health ScienceUniversity of BueaP.O.Box 63BueaCameroon

Ba.kground:Ga.tric ulcers continue to a.fect millions of people worldwide,with reported ca.es of fa.a.ities a.d the dia.nosis,prevention a.d trea.ment constitute a.burden on the pa.ients especia.ly in ca.e of chronic ulcers which a.e difficult to *** medicines such a. propolis provide suita.le thera.eutic a.terna.ives in the trea.ment a.d cura.ion of ***:This work focused on the eva.ua.ion of the phenolic profile a.d hea.ing effect of Ca.eroonia. propolis on ga.tric ulcers in ***:Identifica.ion a.d qua.tifica.ion of phenolic compounds in the propolis extra.t wa. done using *** ga.tric ulcers were induced using etha.ol(70%;1 mL/200 g p.o.)/indometha.in(1 mg/kg p.o.),a.d“unhea.ed”ga.tric ulcera.ions were induced using a.etic a.id(30%)/indometha.in(1 mg/kg p.o.).The a.ima.s were a.ministered with the vehicle(Tween 20,1 mL/100 g p.o.),propolis extra.t(200 mg/kg,400 mg/kg a.d 600 mg/kg p.o.)or sucra.fa.e(50 mg/kg p.o.),once da.ly for ten to fourteen *** the end of ea.h trea.ment period,the a.ima.s were sa.rificed a.d ulcer indices,ga.tric mucus weight,histologica. a.d oxida.ive stress pa.a.eters were ***:Eight phenolic compounds were identified a.d qua.tified a.d most a.unda.t were Ca.feic a.id(45.31±0.25μg/g),Chrysin(37.65±0.17μg/g)a.d p-Hydroxy benzoic a.id(34.14±0.21μg/g).The trea.ment of ulcera.ed ra.s(chronic a.d unhea.ed ga.tric ulcer models)with propolis extra.t a. 200 mg/kg,400 mg/kg a.d 600 mg/kg resulted in reduction of ulcer index compa.ed to nega.ive controls in both *** ob-serva.ion of stoma.h tissues showed tha. trea.ment with propolis extra.t led to a.dose-dependent norma.iza.ion of the *** wa. a.significa.t increa.e(Pa.d Pa. a.com-pa.ied the hea.ing of the ***,doses of 200 mg/kg,400 mg/kg a.d 600 mg/kg of the propolis extra.t induced a. increa.e in the a.ounts of SOD,ca.a.a.e,nitrite a.d GSH while MDa.concentra.ions d

关键词： Propolis HPLC-Da. Phenolics a.ti-ulcer a.tivity Ga.tric cura.ive property In vivo a.tioxida.t effects