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From“prototype”to“model”:Architectural and spatial development of Block A(1924—1945)of Istanbul’s Heybeliada Sanatorium

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Frontiers of Architectural Research 2024年第1期13卷 1-20页

作者： Deniz Avci-Hosanli cansu Degirmencioglu Department of Interior Architecture and Environmental Design Izmir University of EconomicsIzmir 35330Turkey TUM School of Engineering and Design Department of ArchitectureTechnical University of MunichMunich 80333Germany

This article examines Block A,the first block-style building in Heybeliada Sanatorium in *** purpose of this research is to understand its architectural and spatial development and discuss how in fact it was a“prototype”of Turkish *** with a three-step methodology(documentation/evaluation/results)this research conducts architectural and spatial analysis on Block *** sources like architectural documentation and restitution drawings,the writings of the institution’s head doctor Tevfik Ismail Gökçe,periodicals on tuberculosis(TB),as well as pertinent literature are *** findings demonstrate that Block A’s development(1924—1945)was the result of knowledge transfer that introduced the universal sanatorium design principles,spatial experiments,adaptation to sociocultural norms,and trial-and-error *** only it had a major impact on shaping of the second block-type building in the complex,the“model”Block B,but it also became exemplary of the subsequent Turkish *** originality of this article is its exploration of the changing and evolving Block A in its resonation with the cultural tensions of Turkey’s modernization *** was established via the assessment of budgetary issues,medical developments and climatic experiments,the social issue of scarcity of TB beds in the country,spatial practices to separate the sexes as reflections of local traditions and culture in the shaping of spaces.

关键词： Sanatorium architecture Tuberculosis History of healthcare Early republican Turkey Istanbul

Enzymatic Synthesis and Characterization of Biodegradable Poly(w-pentadecalactone-co-ε-caprolactone)Copolymers

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Journal of Renewable Materials 2018年第6期6卷 591-598页

作者： cansu ulker Yuksel Guvenilir Istanbul Technical University Department of Chemical Engineering34469IstanbulTurkey

As an alternative biodegradable aliphatic polyester,poly(w-pentadecalactone-co-ε-caprolactone)copolymer was synthesized via enzymatic ring-opening polymerization.A new biocatalyst,Candida antarctica lipase B,immobilized onto rice husk ash was used for *** were carried out at various temperatures and periods for varied copolymer compositions in order to obtain the highest molecular weight *** best reaction parameters were found to be 80℃ and 6 hours and molecular weights increased proportionally with the amount of w-pentadecalactone(w-PDL).The molecular structure of copolymer with 75%weight ratio of w-PDL(Mn=19720 g/mol)was characterized by proton and carbon nuclear magnetic resonance spectroscopies(^1H-NMR and ^13C-NMR).Thermal properties of the same copolymer and homopolymers were investigated by differential scanning calorimetry(DSC)and thermogravimetric analysis(TGA).Improved thermal features were shown by addition of w-PDL to the structure and compared with poly(ε-caprolactone)(PCL).Consequently,poly(w-pentadecalactone-co-ε-caprolactone)copolymers were found to be good alternatives to widely used polyester,PCL,with their rapid polymerization tendency,higher molecular weights,and improved thermal features.

关键词： Candida antarctica lipase B immobilized lipase rice husk ash copolymerization enzymatic ring-opening polymerization lactones ε-caprolactone ω-pentadecalactone

A case of post traumatic mitral chordae rupture mimicking acute respiratory distress syndrome

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World Journal of Emergency Medicine 2024年第4期15卷 322-324页

作者： Hülya Deniz Misir Nalan Demir Ferit Kasimzade cansu Yahşi Intensive Care Department Ankara Bilkent City HospitalAnkara 06800Turkiye Intensive Care Department University of Health Sciences Ankara Bilkent City HospitalAnkara 06800Turkiye Cardiovascular Surgery Department Ankara Bilkent City HospitalAnkara 06800Turkiye Pulmonary Medicine Department University of Health Sciences Ankara Bilkent City HospitalAnkara 06800Turkiye

Traumatic mitral chordae rupture is a rare and known cause of acute mitral valve regurgitation and de novo heart *** pathologies in a trauma patient may mask the findings of de novo heart failure due to mitral chordae *** patients may also have other potential pre-diagnoses that could explain symptoms related to heart failure,such as tachycardia,circulatory shock,and acute *** possibility of traumatic chordae tendinea rupture being a preventable cause of mortality should be carefully evaluated.

关键词： rupture mitral acute

Continuous Lithium-Ion Extraction From Seawater and Mine Water With a Fuel Cell System and Ceramic Membranes

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Energy & Environmental Materials 2024年第6期7卷 254-261页

作者： cansu Kök Lei Wang Jean Gustavo A.Ruthes Antje Quade Matthew E.Suss Volker Presser INM–Leibniz Institute for New Materials Campus D2266123Saarbr¨uckenGermany Department of Materials Science&Engineering Saarland UniversityCampus D2266123Saarbr¨uckenGermany Leibniz Institute for Plasma Science and Technology Felix-Hausdorff-Straße 217489GreifswaldGermany Faculty of Mechanical Engineering Technion–Israel Institute of TechnologyHaifa3200003Israel Wolfson Department of Chemical Engineering Technion–Israel Institute of TechnologyHaifa3200003Israel Grand Technion Energy Program Technion–Israel Institute of TechnologyHaifa3200003Israel Saarene–Saarland Center for Energy Materials and Sustainability Campus C4266123Saarbr¨uckenGermany

The demand for electronic devices that utilize lithium is steadily increasing in this rapidly advancing technological *** high-purity lithium in an environmentally friendly way is challenging by using commercialized ***,we propose the first fuel cell system for continuous lithium-ion extraction using a lithium superionic conductor membrane and advanced *** fuel cell system for extracting lithium-ion has demonstrated a twofold increase in the selectivity of Li^(+)/Na^(+)while producing *** data show that the fuel cell with a titania-coated electrode achieves 95%lithium-ion purity while generating 10.23 Wh of energy per gram of *** investigation revealed that using atomic layer deposition improved the electrode's uniformity,stability,and electrocatalytic *** 2000 cycles determined by cyclic voltammetry,the electrode preserved its stability.

关键词： atomic layer deposition cation selectivity electrochemical lithium-ion extraction fuel cell

Covering the More Visible Region by Electrochemical Copolymerization of Carbazole and Benzothiadiazole Based Donor-Acceptor Type Monomers

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Chinese Journal of Polymer Science 2019年第1期37卷 28-35页

作者： Emine Gul cansu-Ergun Department of Electrical and Electronics Engineering Baskent University

An electrochromic copolymer film of 2-(3,3-dihexyl-3,4-dihydro-2 H-thieno[3,4-b][1,4]dioxepin-6-yl)-7-(3,3-dihexyl-3,4-dihydro-2 H-thieno[3,4-b][1,4]dioxepin-8-yl)-9 H-carbazole(M1) and 4,7-bis(thiophen-2-yl)benzo[c][1,2,5]thiadiazole(M2) was prepared via electrochemical technique. The copolymerization was performed with one to one monomer feed ratio. Electrochemical and optical properties of the resulting copolymer film(P3) and the homopolymer films of M1 and M2(P1 and P2) were investigated by using cyclic voltammetry and UV-Vis spectrometry techniques, and the corresponding results were compared. Incorporation of M1 and M2 into copolymer matrix was clearly observed on the resulting cyclic voltammograms and UV-Vis spectra. P3 covered the visible regions coming from both P1 and P2, and exhibited a neutral state darker color than those of homopolymers. P3 film was found to have a multichromic behavior, appearing as brown in its neutral state while changing its color upon oxidation to dark-gray(at about 0.3 V), to blue(at about 0.6 V) and finally to grayish cyan(beyond 0.9 V), with a corresponding optical band gap of 1.65 eV.

关键词： Electrochemical polymerization Copolymer Electrochromic polymers

Dithiothreitol and PEG Induced Combined Stress May Affect the Expressions of ABA Aldehyde Oxidase, Sucrose Synthase and Proline Metabolic Genes in Maize Seedlings

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Phyton-International Journal of Experimental Botany 2020年第3期89卷 487-495页

作者： cansu Altuntas Rabiye Terzi Faculty of Science Department of BiologyKaradeniz Technical UniversityTrabzon61080Turkey

The endoplasmic reticulum(ER)is an organelle in the cell where proteins are created and *** is a very elaborate process that is often interrupted by various biotic and abiotic stresses,leading to the formation of unfolded and misfolded proteins called ER ***(DTT)-induced unfolded protein response(UPR)in endoplasmic reticulum(ER)has been recently reported in ***,previous studies demonstrated that treatment with polyethylene glycol(PEG 6000)could stimulate water deficit in ***,further researches should be conducted to elucidate the molecular mechanism of ER stress response and the relationship between water deficiency and *** this study,we examined the expressions of sucrose synthase(SuS)gene,proline metabolic genes and abscisic aldehyde oxidase(AAO3)gene in maize seedlings that were subjected to DTT and PEG induced combined stresses by using quantitative real-time *** weeks old detached maize seedlings were treated with or without DTT and PEG 6000 for 12 *** treatment with DTT increased about 2-fold the expression of gene encoding proline synthesis enzyme,pyrroline-5-carboxylate synthetase(P5CS)but no statistically affected the proline catabolism enzyme,proline dehydrogenase(ProDH)in comparison with un-treated *** treatment was also up-regulated P5CS while it was down-regulated *** relative expression levels of SuS and AAO3 genes statistically enhanced about 2.5 fold under the DTT-induced ER ***,the expression levels of SuS and AAO3 genes were up-regulated in the detached seedlings exposed to PEG-induced water ***,the induced gene expressions were down-regulated under the combined stress,the DTT-induced ER stress and PEG-induced water deficit in comparison with the singular stress responses(DTT or PEG).The results indicated that the expressions of genes,related to the synthesis of some signal osmolyte compounds such as proline and sucrose can be suppressed when ER s

关键词： ER stress water deficit sucrose proline metabolism ABA synthesis gene expression

Modeling of dynamic response of poroelastic soil layers under wave loading

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Frontiers of Structural and Civil Engineering 2014年第1期8卷 1-18页

作者： Mehmet Baris Can ulker Earthquake Engineering and Disaster Management Institute Istanbul Technical University Istanbul 34469 Turkey

In this paper, the dynamic response of saturated and layered soils under harmonic waves is modeled using the finite element method. The numerical results are then verified by corresponding analytical solutions which are also developed by the author. The equations governing the dynamics of porous media are written in their fully dynamic form and possible simplifications are introduced based on the presence of inertial terms associated with solid and fluid phases. The response variations are presented in terms of pore water pressure and shear stress distributions within the layers. It is determined that a set of non-dimensional parameters and their respective ratios as a result of layering play a major role in the dynamic response.

关键词： dynamic response of soils coupled flow-deformation finite elements analytical solution harmonic waves

Intraocular pressure elevation after intravitreal triamcinolone acetonide injection: a Meta-analysis

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International Journal of Ophthalmology(English edition) 2016年第1期9卷 139-144页

作者： cansu Yuksel-Elgin Ceyhun Elgin Department of Ophthalmology Sariyer Ismail Akgun Public Hospital Department of Economics Bogazici University

AIM：To report on intraocular pressure（IOP）after intravitreal injections of triamcinolone acetonide.·M ETHODS：Systematic literature review of studies that investigated the effects of an injection of triamcinolone Intravitreal triamcinolone acetonide on IOP was conducted according to the Cochrane Collaboration methodology and the reported effects have been analyzed with Meta-analysis.·RESULTS：We found that the IOP follows an inverted-U shape pattern over time starting with an average value of14.81±1.22 mm Hg before the injection,rising to a maximum of 19.48±2.15 mm Hg after one month of injection and falling down to 16.16±1.92 mm Hg ***,country of study,age,previous history of glaucoma and gender compositions matter for crossstudy were different in reported IOP changes.·CONCLUSION：Our findings may be helpful in determining pressure elevation risk of intravitreal triamcinolone acetonide therapy as well as comparing it with those of more recent therapies such as the antivascular endothelial growth factor agents.

关键词： intravitreal injections intraocular pressure Meta-analysis

元话语标记在不同英语媒介教学(EMI)学科口语表达中的运用

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Chinese Journal of Applied Linguistics 2024年第2期47卷 281-308,365页

作者：坎苏·艾库特-科莱巴努·伊南-卡拉古尔哈杰泰佩大学土耳其

经过多年的研究,元话语(MD)已成为教育领域的重要概念,尤其在书面语境中得到了广泛关注。元话语允许教师在授课过程中有效地组织课堂话语,并展示个人的教学风格。尽管近年来对口语语境下元话语的研究有所增加,但在不同教育环境下仍需进... 详细信息

经过多年的研究,元话语(MD)已成为教育领域的重要概念,尤其在书面语境中得到了广泛关注。元话语允许教师在授课过程中有效地组织课堂话语,并展示个人的教学风格。尽管近年来对口语语境下元话语的研究有所增加,但在不同教育环境下仍需进一步探索其在实践中的应用。鉴于英语为媒介的教学(EMI)在全球范围内日益普及,MD在EMI课堂话语中所扮演的角色已然成为一个具有研究价值的领域。在土耳其的语境下,MD近期已成为一个备受瞩目的研究领域。然而,关于土耳其语境中口语互动中的MD的研究却相对较少。本研究旨在深入探究教师在不同EMI课程的口语教学中,对于元话语标记的分布情况以及词法实现的具体表现。研究以?del(2010)提出的元话语框架为参照,运用语料库方法进行了话语分析。通过对36小时课堂观察所收集的语料进行严谨的定性与定量分析,我们发现,在不同的EMI课程中,元话语范畴的分布与实现均呈现出一定的差异性。

关键词：元话语课堂话语英语语言教学口语话语