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A decellularized nerve matrix scaffold inhibits neuroma formation in the stumps of transected peripheral nerve after peripheral nerve injury

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Neural Regeneration Research 2023年第3期18卷 664-670页

作者： Shuai Qiu Pei-Jun Deng Fu-Lin He Li-Wei Yan Zhe-Hui Tu Xiao-Lin Liu Da-Ping Quan Ying Bai can-bin zheng Qing-Tang Zhu Department of Microsurgery and Orthopedic Trauma The First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Department of Orthopedic Surgery The Seventh Affiliated HospitalSun Yat-sen UniversityShenzhenGuangdong ProvinceChina Department of Pediatric Orthopedics Guangzhou Women and Children’s Medical CenterGuangzhou Medical UniversityGuangzhouGuangdong ProvinceChina Guangdong Provincial Peripheral Nerve Tissue Engineering and Technology Research Center GuangzhouGuangdong ProvinceChina Guangdong Province Engineering Laboratory for Soft Tissue Biofabrication GuangzhouGuangdong ProvinceChina School of Chemistry Sun Yat-sen UniversityGuangzhouGuangdong ProvinceChina School of Material Science and Engineering Sun Yat-sen UniversityGuangzhouGuangdong ProvinceChina

Traumatic painful neuroma is an intractable clinical disease characterized by improper extracellular matrix(ECM)deposition around the injury *** have shown that the microstructure of natural nerves provides a suitable microenvironment for the nerve end to avoid abnormal hyperplasia and neuroma *** this study,we used a decellularized nerve matrix scaffold(DNM-S)to prevent against the formation of painful neuroma after sciatic nerve transection in *** results showed that the DNM-S effectively reduced abnormal deposition of ECM,guided the regeneration and orderly arrangement of axon,and decreased the density of regenerated *** epineurium-perilemma barrier prevented the invasion of vascular muscular scar tissue,greatly reduced the invasion ofα-smooth muscle actin-positive myofibroblasts into nerve stumps,effectively inhibited scar formation,which guided nerve stumps to gradually transform into a benign tissue and reduced pain and autotomy behaviors in *** findings suggest that DNM-S-optimized neuroma microenvironment by ECM remodeling may be a promising strategy to prevent painful traumatic neuromas.

关键词： decellularized nerve matrix scaffold extracellular matrix fibrosis functional recovery microarchitecture microenvironment pain peripheral nerve tissue remodeling traumatic neuroma

Optimization-based mode selection scheme for OAM millimeter wave system in the off-axis misalignment case

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Digital Communications and Networks 2024年第1期10卷 101-108页

作者： Haie Dou Lei Wang bin Kang Baoyu zheng Key Lab of Broadband Wireless Communication and Sensor Network Technology(Nanjing University of Posts and Telecommunications) Ministry of EducationNanjing210003China School of Internet of Things Nanjing University of Posts and TelecommunicationsNanjing210003China

Millimeter-wave transmission combined with Orbital Angular Momentum(OAM)has the advantage of reducing the loss of beam power and increasing the system ***,to fulfill this advantage,the antennas at the transmitter and receiver must be parallel and coaxial;otherwise,the accuracy of mode detection at the receiver can be seriously *** this paper,we design an OAM millimeter-wave communication system for overcoming the above ***,the first contribution is that the power distribution between different OAM modes and the capacity of the system with different mode sets are analytically derived for performance *** second contribution lies in that a novel mode selection scheme is proposed to reduce the total interference between different *** results show that system performance is less affected by the offset when the mode set with smaller modes or larger intervals is selected.

关键词： Orbital angular momentum Millimeter wave Off-axis misalignment Mode selection Capacity

Exploring Trade-offs in Thermal Interface Materials:The Impact of Polymer-Filler Interfaces on Thermal Conductivity and Thixotropy

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Chinese Journal of Polymer Science 2024年第7期42卷 916-925,I0006页

作者： bin Zhang zheng-Li Dou Yong-zheng Zhang Qiang Fu Kai Wu College of Polymer Science and Engineering State Key Laboratory of Polymer Materials EngineeringSichuan UniversityChengdu610065China

Effective thermal transport across solid-solid interfaces which is essential in thermal interface materials(TIMs),necessitates both optimal thixotropy and high thermal *** role of filler surface modification,a fundamental aspect of TIM fabrication,in the influence of these properties is not fully *** study employs the use of a silane coupling agent(SCA)to modify alumina,integrating experimental approaches with molecular dynamics simulations,to elucidate the interface effects on thixotropy and thermal conductivity in polydimethylsiloxane(PDMS)-based *** findings reveal that the variations of SCAs modify both interface binding energy and transition layer *** interface binding energy restricts macromolecular segmental relaxation near the interface,hindering desirable thixotropy and bond line *** the contrary,the thickness of the transition layer at the interface positively influences thermal conductivity,facilitating the transport of phonons between the polymer and ***,selecting an optimal SCA allows a balance between traditionally conflicting goals of high thermal conductivity and minimal bond line thickness,achieving an impressively low interface thermal resistance of just 2.45-4.29 K·mm^(2)·W^(-1)at275.8 kPa.

关键词： Thermal interface material Surface modification Thermal conductivity Thixotropy Interface thermal resistance

Electrolyte effect on electrochemical behaviors of manganese fluoride material for aqueous asymmetric and symmetric supercapacitors

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Rare Metals 2024年第3期43卷 1048-1061页

作者： zheng-Hua He Jian-Fei Gao Ling-bin Kong State Key Laboratory of Advanced Processing and Recycling of Non-Ferrous Metals Lanzhou University of TechnologyLanzhou730050China School of Materials Science and Engineering Lanzhou University of TechnologyLanzhou730050China

Exploring wide voltage window materials is not only an available measure to enhance the energy density of hybrid supercapacitor(HSCs),but also avoids the dynamic mismatch caused by different energy storage mechanisms of two electrodes in assembled symmetrical ***,there are few reports about the wide potential window materials except Bi_(2)O_(3)and VO_(2).Therefore,the MnF_(2)synthesized by solvothermal reaction was served as the electrode for *** MnF_(2)exhibited electrochemical activity in alkaline solution in three-electrode system,especially with a wide potential window from-0.8 to+0.5 V in 2 mol·L^(-1)***,the assembled MnF_(2)//MnF_(2)symmetrical HSC had a potential window of 1.5 V,and it exhibited outstanding long-cycle ***,when MnF_(2)was taken as the negative and positive respectively,the potential windows of asymmetric devices CoMoO_(4)//MnF_(2)and MnF_(2)//Activated Carbon(AC)could reach 1.3 and 1.45 V,respectively,showing excellent cycle *** work shows that MnF_(2)material has great research value in HSC,and provides a new research direction for developing high-performance devices.

关键词： Manganese fluoride Potential window Hybrid supercapacitors Electrochemical performance

One-step construction of strongly coupled Co_(3)V_(2)O_(8)/Co_(3)O_(4)/MXene heterostructure via in-situ Co-F bonds for high performance all-solid-state asymmetric supercapacitors

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Rare Metals 2024年第2期43卷 682-691页

作者： Ji Zhou bin-bin Liu Hu zheng Wen-Qing Ma Qian Li Cai-Xia Xu Institute for Advanced Interdisciplinary Research(iAIR) Collaborative Innovation Center of Technology and Equipment for Biological Diagnosis and Therapy in Universities of ShandongSchool of Chemistry and Chemical EngineeringUniversity of JinanJinan250022China

Co_(3)V_(2)O_(8)/Co_(3)O_(4)/Ti_(3)C_(2)T_(x) composite was easily synthesized via one-step succinct-operated hydrothermal *** interconnected Co_(3)V_(2)O_(8)/Co_(3)O_(4) nanowires network can in-situ grow and anchor on the surface of Ti_(3)C_(2)T_(x) via the strong Co-F bonds and contribute tremendously to depress Ti_(3)C_(2)T_(x) *** from the synergistically interplayed effect among the multiple interfaces and high conductivity of Ti_(3)C_(2)T_(x) as well as outstanding stability of the as-designed nanostructure,the optimum Co_(3)V_(2)O_(8)/Co_(3)O_(4)/Ti_(3)C_(2)T_(x)electrode reaches a commendable specific capacitance(up to 3800 mF·cm^(−2)),great rate capability(80%capacitance retention after 20-times current increasing),and preeminent cycling stability(95.4%/85.5%retention at 7000th/20,000th cycle).Moreover,the all-solid-state asymmetric supercapacitor based on Co_(3)V_(2)O_(8)/Co_(3)O_(4)/Ti_(3)C_(2)T_(x) and active carbon can deliver a high energy density of 84.0μWh·cm^(−2) at the power energy of 3.2 mW·cm^(−2),and excellent cycling durability with 87.0%of initial capacitance retention upon 20,000 *** work provides a practicable pathway to tailor MXene-based composites for high-performance supercapacitor.

关键词： Ti_(3)C_(2)T_(x) Co_(3)V_(2)O_(8)/Co_(3)O_(4) Heterostructure Cathode Supercapacitor

Experimental,Numerical,and Analytical Studies on the Bending of Mechanically Lined Pipe

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China Ocean Engineering 2024年第2期38卷 221-232页

作者： WEI Wen-bin YUAN Lin ZHOU Jia-sheng LIU zheng State Key Laboratory of Hydraulic Engineering Simulation and Safety Tianjin UniversityTianjin 300072China School of Civil Engineering Tianjin UniversityTianjin 300072China School of Mechanical Engineering Tianjin UniversityTianjin 300072China

Mechanically lined pipe(MLP)is often used for offshore oil and gas transport because of its low cost and corrosion *** installation and operation,the pipe may undergo severe bending deformation,which causes the liner to separate from the outer pipe and buckles,affecting the stability of the whole *** this paper,the buckling response of MLP subjected to bending is investigated to clarify its bending characteristics by employing both experiments,numerical simulation,as theoretical *** types of MLPs were manufactured with GB 45 carbon steel(SLP)and Al 6061(ALP)used as the outer pipe material,*** hydraulic expansion and bending experiments of small-scale MLPs are *** addition to the ovalized shape of the cross-section for the SLP specimens,the copper liner was found to wrinkle on the compressive *** contrast,the liner of ALP remains intact without developing any wrinkling and collapse *** addition,a dedicated numerical framework and theoretical models were also *** was found both the manufacturing and bending responses of the MLP can be well reproduced,and the predicted maximum moment and critical curvatures are in good agreement with the experimental results.

关键词： lined pipe bending nonlinear ring theory buckling plasticity

Hyperpolarized ^(13)C MRI in hepatocellular carcinoma:Unmet questions during clinical translation

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Chinese Medical Journal 2024年第13期137卷 1516-1518页

作者： zheng Ye bin Song Christoffer Laustsen Department of Radiology West China HospitalSichuan UniversityChengduSichuan 610041China The MR Research Center Department of Clinical MedicineAarhus UniversityAarhus N 8200Denmark

Hyperpolarized(HP)^(13)C magnetic resonance imaging(MRI)is a powerful molecular imaging *** dissolution dynamic nuclear polarization(d-DNP),it can achieve dramatic signal increase and allows for dynamic and quantitative investigation of real-time metabolism in vivo.[1]The typical HP^(13)C MRI workflow begins with formulating the^(13)C probe,and then placing it in the hyperpolarization equipment to achieve the desired signal amplification level,which typically amounts to an increase in the MRI signal by more than 10,000 *** subsequent data acquisition is supported by a specialized^(13)C coil and^(13)C acquisition sequence,and finally quantitative and visualized metabolic information is obtained through a post-processing *** date,research of HP^(13)C MRI has focused on diabetes,cardiovascular diseases,and cancers,[2]showing great promises in tumor detection and the evaluation of therapeutic efficacy.

关键词： metabolism polarized specialized

Optimal production strategy for auto manufacturers with government subsidies in competitive environments

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Frontiers of Engineering Management 2024年第2期11卷 345-355页

作者： Jingjing XUE bin zheng Sijie LI School of Economics and Management Nanjing Tech UniversityNanjing 211816China School of Economics and Management Southeast UniversityNanjing 211189China

Using the Hotelling model and evolutionary game theory,this paper studies the optimal production strategy of duopoly auto manufacturers and explores the impacts of two government policies(manufacturer and consumer subsidies)on strategies related to the production of electric vehicles(EVs)or fuel vehicles(FVs).The study finds that consumers’environmental preferences have direct effects on manufacturers’market shares and profits,which in turn,affect the manufacturers’production strategy ***,when consumer environmental preference is sufficiently high,both auto manufacturers will eventually choose to produce EVs;when it is moderate,only one with a cost advantage will choose to produce ***,when it is low,neither auto manufacturer will produce *** findings further reveal that the more significant the difference in EV production costs is,the more inclined auto manufacturers are to choose a different final stable *** of whether the government subsidizes manufacturers or consumers,the policy only works if subsidies reach a certain *** study also identifies the conditions under which government subsidies are considered more cost-effective.

关键词： supply chain management low-carbon emission electric vehicle subsidy evolutionary game theory

Fabrication of AZ31/Mg3Y Composites with Excellent Strength and Plasticity via Accumulated Rolling Bonding and Diffusion Annealing

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Acta Metallurgica Sinica(English Letters) 2024年第2期37卷 339-352页

作者： Yang Feng Wenhuan Chen zheng Xu Weijun He bin Jiang Fusheng Pan College of Materials Science and Engineering Chongqing UniversityChongqing400044China International Joint Laboratory for Light Alloys(Ministry of Education) Chongqing UniversityChongqing400044China

AZ31/Mg3Y composites with a layer thickness of 100-200μm were fabricated by accumulated rolling bonding(ARB),which was followed by diffusion annealing at 300℃ for 0-32 *** interface layer,containing numerous Al-Y precipitates,is formed in the Mg3Y layer that is adjacent to the interface as a result of Al diffusing from the AZ31 layers into the Mg3Y *** thickness of the interface layer gets increased and more precipitates are formed in the interface layer with the extension of the annealing *** microhardness of the AZ31 and Mg3Y layer decreases firstly and then reaches a stable value,while the microhardness of the interface layer increases gradually with the extension of the annealing *** AZ31/Mg3Y composites exhibit equivalent strength but increased ductility after diffusion annealing,in comparison to the as-rolled AZ31/Mg3Y *** addition,the AZ31/Mg3Y composites after annealing always present higher strength and ductility than AZ31/AZ31 composite,which was fabricated by the same process as that for the AZ31/Mg3Y ***-deformation induced strengthening also plays an important role in the excellent strength and ductility of the annealed AZ31/Mg3Y *** study can provide a direction for improving the plasticity and strength of magnesium alloys synergistically.

关键词： AZ31/Mg3Y composite Accumulated rolling bonding Diffusion annealing Precipitates Strengthening