Therapeutic plasma exchange for hyperlipidemic pancreatitis:Current evidence and unmet needs

作     者：Can-Bin Zheng Zi-Hui Zheng Yong-Ping Zheng 

作者机构：Department of Endocrine and Metabolic DiseaseShantou Central HospitalShantou 515031Guangdong ProvinceChina Nursing CollegeGuangdong Pharmaceutical UniversityGuangzhou 510000Guangdong ProvinceChina Department of GastroenterologyShantou Central HospitalShantou 515031Guangdong ProvinceChina 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2021年第9卷第21期

页      面：5794-5803页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Therapeutic plasma exchange Hyperlipidemic acute pancreatitis Evidence Outcome Future direction 

摘      要：With changes in lifestyle and diet worldwide,the prevalence of hyperlipidemic acute pancreatitis(HLAP)has greatly increased,and it has become the most common cause of acute pancreatitis not due to gallstones or *** are many available therapies for HLAP,including oral lipid-lowering agents,intravenous insulin,heparin,and therapeutic plasmapheresis(TPE).It is believed that the risk and severity of HLAP increase with rising levels of serum triglycerides(TG),thus a rapid decrease in serum TG level is the key to the successful management of *** has emerged as an effective modality in rapidly reducing serum TG ***,due to its cost and accessibility,TPE remains poorly evaluated until *** studies revealed its efficacy in helping to treat and prevent the recurrence,while some studies suggested that TG levels were not correlated with disease severity,mortality,or length of hospital *** TPE might have no beneficial effect for the *** article gives an overview of the published evidence of TPE in the treatment of HLAP and outlines current evidence regarding individual outcome predictors,adverse effects of the procedure,and TPE in special occasions such as for pregnant patients and patients with diabetic *** direction of TPE research for HLAP is also discussed in this review.