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不同施肥方式对青贮玉米生长及品质的影响

中国土壤与肥料 2024年第8期 188-197页

作者：李智贤陈佳钰鲁泽让黎晓璐李永梅范茂攀赵吉霞云南农业大学资源与环境学院云南昆明650201

探究不同施肥方式对云南省红壤耕地土壤理化性质、青贮玉米生长以及肥料利用效率的影响,以探明最佳施肥方式,为青贮玉米科学施肥提供依据。在云南昭通开展青贮玉米田间试验,分别设置不施肥(CK)、施用复合肥(T1,传统施肥方式)、施用配方... 详细信息

探究不同施肥方式对云南省红壤耕地土壤理化性质、青贮玉米生长以及肥料利用效率的影响,以探明最佳施肥方式,为青贮玉米科学施肥提供依据。在云南昭通开展青贮玉米田间试验,分别设置不施肥(CK)、施用复合肥(T1,传统施肥方式)、施用配方肥(T2)、施用控释肥(T3)4个施肥处理,研究不同施肥处理下土壤养分变化及植株养分利用对青贮玉米的农艺性状、作物产量和营养品质的影响,为探讨优质高产的青贮玉米种植施肥方式提供依据。结果显示:(1)等纯养分量条件下,配方肥和控释肥施用对土壤性质的改良有一定作用,T2处理的土壤碱解氮、速效钾和有机质含量较T1处理分别显著提升15.83%、10.47%和1.95%,T3较T1处理显著提高了9.51%和1.38%的土壤有效磷含量和pH;(2)T3处理干物质量和鲜物质量最高,分别为38.06和126.53 t/hm2,较T1处理分别显著提高了7.30%和16.49%,较T2处理分别提高了1.09%和3.71%;(3)T3处理较T1处理的青贮玉米成熟期地上部植株氮、磷和钾吸收量的积累分别显著提高了27.67%、8.29%和13.82%;T3处理较其余处理均显著提高了肥料偏生产力和肥料农学效率,较常规施肥处理T1处理分别提高了27.65%和138.43%,且T3处理的肥料贡献率最高,较T1处理显著提高了23.23%;地力贡献率表现为T1>T2>T3;(4)T2处理的粗蛋白和粗脂肪含量最高,较T1处理分别显著提高了16.56%和4.28%,粗灰分和中、酸性洗涤纤维的含量最低,与T1处理相比分别显著降低了14.68%、12.08%和1.34%,所以T2处理的相对饲喂价值和粗饲料分级指数达到最大,分别为388.21和290.47 MJ/d,施用控释肥次之。冗余分析得出土壤碱解氮是影响青贮玉米饲用品质的主导因子。综上所述,与常规施肥相比,配方肥的施用通过显著提高土壤固肥能力,促进肥料利用效率,从而提高青贮玉米的营养品质;控释肥的施用使得青贮玉米全生育期的氮素供给得到满足,避免氮素的大量流失,达到青贮玉米高产及肥料高效利用。

关键词：青贮玉米土壤速效养分产量营养品质肥料利用效率

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毛细胞型星形细胞瘤116例临床病理及分子遗传学特征分析

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诊断病理学杂志 2024年第7期31卷 603-608页

作者：徐玉霞魏思航王芳吴小延中山大学肿瘤防治中心分子诊断科广州510060 广州医科大学附属肿瘤医院放疗中心广州510060

目的探讨毛细胞型星形细胞瘤(PA)临床病理及分子遗传学特征,分析预后相关因素。方法回顾性分析116例PA患者临床病理随访资料及治疗信息,分析各指标预后意义。结果116例PA主要临床表现为头晕头痛和共济失调。免疫组化结果显示GFAP、Olig-... 详细信息

目的探讨毛细胞型星形细胞瘤(PA)临床病理及分子遗传学特征,分析预后相关因素。方法回顾性分析116例PA患者临床病理随访资料及治疗信息,分析各指标预后意义。结果116例PA主要临床表现为头晕头痛和共济失调。免疫组化结果显示GFAP、Olig-2、ATRX、S-100阳性表达,IDH1阴性表达,NeuN大部分阴性表达,Ki-67增殖指数低,p53蛋白呈弱阳性或阴性表达,1p/19q绝大部分无缺失。KIAA1549-BRAF融合基因阳性率在年龄和肿瘤部位的差异有统计学意义(P<0.05)。Log-rank单因素分析结果显示,肿瘤切除率是影响本组患者PFS的主要因素(P<0.05),年龄,性别,肿瘤部位、KIAA1549-BRAF融合基因对生存率的影响无统计学意义。Cox回归分析结果显示,肿瘤切除率仍是影响PFS的独立危险因素(P<0.05)。结论手术完整切除是PA首选治疗方式。分子遗传学特征及正确的组织形态学判断对于PA的精确诊断具有重要作用。

关键词：毛细胞星形细胞瘤 KIAA1549-BRAF融合鉴别诊断肿瘤切除预后

含哒嗪功能结构酰胺醚类化合物的合成及其缓蚀性能的实验评价与理论模拟

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高等学校化学学报 2024年第10期45卷 97-109页

作者：任峻晴马玉乐马宇欣高少琪仇宇豪陈国博夏树伟于良民中国海洋大学化学化工学院青岛266100 中国海洋大学海洋化学理论与工程技术教育部重点实验室青岛266100

为了解决碳钢在工业应用中的腐蚀状况,设计合成了3种含哒嗪功能结构的酰胺醚类化合物(PCAE).采用电化学分析和表面测试等实验方法探究了其在1 mol/L盐酸中对碳钢的缓蚀性能,结果表明,PCAE是以抑制阳极为主的混合型缓蚀剂,PCAE1和PCAE2... 详细信息

为了解决碳钢在工业应用中的腐蚀状况,设计合成了3种含哒嗪功能结构的酰胺醚类化合物(PCAE).采用电化学分析和表面测试等实验方法探究了其在1 mol/L盐酸中对碳钢的缓蚀性能,结果表明,PCAE是以抑制阳极为主的混合型缓蚀剂,PCAE1和PCAE2浓度为500 mg/L时缓蚀率分别为96.8%和93.1%,而PCAE3在100 mg/L时缓蚀率即可达到96.5%.PCAE在碳钢表面以化学吸附为主,符合Langmuir等温式,在缓蚀剂作用下的碳钢表面腐蚀坑明显减少,粗糙度曲线趋于平缓.量子化学计算结果表明,PCAE的结构中含有大量活性吸附位点,PCAE3分子最低未占据轨道(LUMO)接受金属电子形成反馈键的能力更占优势,其支链取代基中的C_(2pz)和羰基O_(2pz)对LUMO轨道的贡献较大.

关键词：缓蚀剂电化学技术吸附量子化学计算

variation in expression of small ubiquitin-like modifiers in injured sciatic nerve of mice

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Neural Regeneration Research 2019年第8期14卷 1455-1461页

作者： Dian-Ying Zhang Kai yu Zhong Yang xiao-Zhi Liu xiao-Fang Ma Yan-xia Li Department of Orthopedics and Trauma People's Hospital Peking University Beijing China Department of Orthopedics Tianjin Fifth Central Hospital Tianjin China Central Laboratory Tianjin Fifth Central Hosp让al Tianjin China

Small ubiquitin-like modifiers (SUMOs) have been shown to regulate axonal regeneration, signal transduction, neuronal migration, and myelination, by covalently and reversibly attaching to the protein substrates during neuronal cell growth, development, and differentiation. It has not been reported whether SUMOs play a role in peripheral nerve injury and regeneration. To investigate any association between SUMOylation and potential neuroprotective effects during peripheral nerve injury and regeneration, C57/BL mice were randomly divided into sham and experimental groups. The sciatic nerve was exposed only in the sham group. The experimental group underwent neurotomy and epineurial neurorrhaphy. Real-time quantitative polymerase chain reaction and western blot assay results revealed different mRNA and protein expression levels of SUMO1, SUMO2, SUM03 and UBC9 in sciatic nerve tissue (containing both 5 mm of proximal and distal stumps at the injury site) at various time points after injury. Compared with the sham group, protein levels of SUM01 and SUMO2/3 increased in both their covalent and free states after sciatic nerve injury in the experimental group, especially in the covalent state. UBC9 protein levels showed similar changes to those of SUMO1 and SUMO2/3 in the covalent states. Immunohistochemical staining demonstrated that SUMO1 and SUMO2/3 immunopositivities were higher in the experimental group than in the sham group. Our results verified that during the repair of sciatic nerve injury, the mRNA and protein expression of SUMO1, SUMO2, SUMO3 and UBC9 in injured nerve tissues changed in varying patterns and there were clear changes in the expression of SUMO-related proteins. These findings reveal that SUMOs possibly play an important role in the repair of peripheral nerve injury. All animal protocols were approved by the Institutional Animal Care and Use Committee of Tianjin Fifth Central Hospital, China (approval No. TJWZXLL2018041) on November & 2018.

关键词： nerve regeneration peripheral nerve injury sciatic nerve SUMO1 SUMO2/3 UBC9 SUMOylation epineurial neurorrhaphy neural regeneration

Printability during projection-based 3D bioprinting

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Bioactive Materials 2022年第5期7卷 254-267页

作者： Kang yu Xinjie Zhang yuan Sun Qing Gao Jianzhong Fu Xiujun cai Yong He State Key Laboratory of Fluid Power and Mechatronic Systems College of Mechanical EngineeringZhejiang UniversityHangzhou 310027China Department of General Surgery Sir Run-Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016China Key Laboratory of Materials Processing and Mold Zhengzhou UniversityZhengzhou450002China Key Laboratory of 3D Printing Process and Equipment of Zhejiang Province College of Mechanical EngineeringZhejiang UniversityHangzhou 310027China Zhejiang Research and Development Engineering Laboratory of Minimally Invasive Technology and Equipment Hangzhou310016China Cancer Center Zhejiang UniversityHangzhouZhejiang 310058 China

Since projection-based 3D bioprinting(PBP)could provide high resolution,it is well suited for printing delicate structures for tissue ***,the low crosslinking density and low photo-crosslinking rate of photocurable bioink make it difficult to print fine ***,an in-depth understanding of the is ***,a research framework is established for the analysis of printability during *** gelatin methacryloyl(GelMA)-based bioink is used as an example,and the printability is systematically *** analyze the photo-crosslinking reactions during the PBP process and summarize the specific requirements of bioinks for *** standard quantized models are established to evaluate 2D and 3D printing ***,the better strategies for bioprinting five typical structures,including solid organs,vascular structures,nerve conduits,thin-wall scaffolds,and micro needles,are presented.

关键词： Projection-based printing(PBP) 3D bioprinting GelMA bioink Rheological analysis

工程认证背景下大学化学基础课程达成度评价体系构建及教学改革探索

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安徽化工 2024年第2期50卷 189-192页

作者：曾宪彩李梦硕张莉刘玉洁南阳理工学院生物与化学工程学院河南南阳473004

工程教育认证是保障工程教育质量的国际通行制度,是我国高等教育的大趋势。以南阳理工学院机械制造与自动化专业工程认证为基础,阐述了大学化学基础课程的课程目标与毕业要求指标点的关系、课程目标达成度的评价方法,并以2021-2022学年... 详细信息

工程教育认证是保障工程教育质量的国际通行制度,是我国高等教育的大趋势。以南阳理工学院机械制造与自动化专业工程认证为基础,阐述了大学化学基础课程的课程目标与毕业要求指标点的关系、课程目标达成度的评价方法,并以2021-2022学年为例进行了达成度评价分析,对课程的持续改进方法进行了探索。

关键词：工程认证大学化学基础达成度评价持续改进

Research progress of heat stroke during 1989–2019: A bibliometric analysis

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Military Medical Research 2021年第3期8卷 384-394页

作者： De-Meng xia Xu-Ren Wang Pan-yu Zhou Tian-Le Ou Lei Su Shuo-Gui Xu Department of Emergency Changhai Hospitalthe Naval Medical UniversityShanghai 200433China Nursing College The Naval Medical UniversityShanghai 200433China Department of Clinical Medicine The Naval Medical UniversityShanghai 200433China Department of Intensive Care Unit General Hospital of Southern Theater CommandGuangzhou 510010China

Background: Heat stroke(HS) is an acute physical disorder that is associated with a high risk of organ dysfunction and even death. HS patients are usually treated symptomatically and conservatively;however, there remains a lack of specific and effective drugs in clinical practice. An analysis of publication contributions from institutions, journals and authors in different countries/regions was used to study research progress and trends regarding ***: We extracted all relevant publications on HS between 1989 and 2019 from Web of Science. Using the Statistical Package for Social Science(SPSS, version 24) and the software GraphPad Prism 8, graphs were generated and statistical analyses were performed, while VOSviewer software was employed to visualize the research trends in HS from the perspectives of co-occurring ***: As of April 14, 2020, we identified 1443 publications with a citation frequency of 5216. The United States accounted for the largest number of publications(36.2%) and the highest number of citations(14,410), as well as the highest H-index at 74. Although the sum of publications from China ranked second, there was a contradiction between the quantity and quality of publications. Furthermore, Medicine & Science in Sports & Exercise published the most papers related to HS, with Lin MT publishing the most papers in this field(112), while the review by Knochel JP received the highest citation frequency at 969. The keyword heat-stress appeared most recently, with an average appearing year of 2015.5. In the clinical research cluster, exertional heat-stroke was determined to be the hotspot, while ambient-temperature and heat waves were the new trends in the epidemiological research ***: Corresponding to this important field, while the contributions of the publications from the United States were significant, the mismatch between the quantity and quality of publications from China must be examined. Moreover, it is hypothesized

关键词： Heat stroke Publications Citation frequency

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江苏省老年人健康服务体系的研究与建议

医学信息 2024年第15期37卷 38-42+47页

作者：潘玉霞王超璠卜云翎张霞薛小燕胡东东杨茜岚南京医科大学第四附属医院护理部江苏省药品价格与招标采购管理中心南京医科大学第四附属医院全科医学科南京医科大学第四附属医院急诊医学科

目的通过分析养老机构的现状，提出有关养老机构创新设想、统筹照护资源、提升养老服务社会化的建议。方法 2022年1月1日-6月30日在江苏省3个地区选取104家养老机构，从设备、提供服务、员工、运营、满意度调查5个方面进行研究。结果 ... 详细信息

目的通过分析养老机构的现状，提出有关养老机构创新设想、统筹照护资源、提升养老服务社会化的建议。方法 2022年1月1日-6月30日在江苏省3个地区选取104家养老机构，从设备、提供服务、员工、运营、满意度调查5个方面进行研究。结果超过50%的养老机构具有普通护理床(94.23%)、消毒(53.85%)、监控(86.54%)、网络与计算机系统(75.00%)、呼叫器(67.31%)等设备；养老机构所提供服务以生活(100.00%)、心理照料(79.81%)、休闲娱乐(93.27%)、临终关怀(79.81%)为主，并能提供Ⅱ级(71.15%)和Ⅲ级(85.58%)护理。养老机构人员学历构成以中专(29.53%)及以下(33.13%)为主，职称以初级职称(32.51%)与无职称(55.46%)为主。养老机构满意度调查得分最低的两项是护工能力和康复设备的配套。结论江苏省失能老人照护扶持制度仍有待进一步完善，需增设配置，培养优质护理人员等措施，积极打造专业的养老服务机构和养老服务队伍，促进医养结合产业的发展。

关键词：养老机构健康服务江苏省老年人

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2型糖尿病血压管理与慢性并发症

中华内分泌代谢杂志 2024年第8期40卷 710-715页

作者：张骏恒王斯宇蔡乐谢婉婷顾昊清杨芊芊张晓云徐晓丽赵璇徐瑜成杰上海交通大学医学院医学技术学院上海200025 上海交通大学医学院附属瑞金医院内分泌代谢病科上海市内分泌代谢病研究所国家代谢性疾病临床医学研究中心上海200025 上海交通大学公共卫生学院上海200025 上海交通大学医学院附属瑞金医院医学教育处上海200025

2型糖尿病合并高血压显著增加心血管、肾脏等慢性并发症发生风险,适宜血压管理对于防治2型糖尿病并发症具有重要意义。本文重点回顾了2型糖尿病血压管理相关临床研究证据与临床实践指南规范,总结探讨2型糖尿病患者高血压起始治疗时机、... 详细信息

2型糖尿病合并高血压显著增加心血管、肾脏等慢性并发症发生风险,适宜血压管理对于防治2型糖尿病并发症具有重要意义。本文重点回顾了2型糖尿病血压管理相关临床研究证据与临床实践指南规范,总结探讨2型糖尿病患者高血压起始治疗时机、降压治疗目标、一线降压药物及随访监测计划。

关键词：糖尿病,2型高血压慢性并发症