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Printability during projection-based 3D bioprinting

作     者:Kang Yu Xinjie Zhang Yuan Sun Qing Gao Jianzhong Fu Xiujun Cai Yong He 

作者机构:State Key Laboratory of Fluid Power and Mechatronic SystemsCollege of Mechanical EngineeringZhejiang UniversityHangzhou 310027China Department of General SurgerySir Run-Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016China Key Laboratory of Materials Processing and MoldZhengzhou UniversityZhengzhou450002China Key Laboratory of 3D Printing Process and Equipment of Zhejiang ProvinceCollege of Mechanical EngineeringZhejiang UniversityHangzhou 310027China Zhejiang Research and Development Engineering Laboratory of Minimally Invasive Technology and EquipmentHangzhou310016China Cancer CenterZhejiang UniversityHangzhouZhejiang 310058 China 

出 版 物:《Bioactive Materials》 (生物活性材料(英文))

年 卷 期:2022年第7卷第5期

页      面:254-267页

核心收录:

学科分类:0831[工学-生物医学工程(可授工学、理学、医学学位)] 08[工学] 0802[工学-机械工程] 0836[工学-生物工程] 080201[工学-机械制造及其自动化] 

基  金:sponsored by the National Key Research and Development Program of China(2018YFA0703000) the National Natural Science Foundation of China of China(No.U1909218) the Science Fund for Creative Research Groups of the National Natural Science Foundation of China(No.T2121004) 

主  题:Projection-based printing(PBP) 3D bioprinting GelMA bioink Rheological analysis 

摘      要:Since projection-based 3D bioprinting(PBP)could provide high resolution,it is well suited for printing delicate structures for tissue ***,the low crosslinking density and low photo-crosslinking rate of photocurable bioink make it difficult to print fine ***,an in-depth understanding of the is ***,a research framework is established for the analysis of printability during *** gelatin methacryloyl(GelMA)-based bioink is used as an example,and the printability is systematically *** analyze the photo-crosslinking reactions during the PBP process and summarize the specific requirements of bioinks for *** standard quantized models are established to evaluate 2D and 3D printing ***,the better strategies for bioprinting five typical structures,including solid organs,vascular structures,nerve conduits,thin-wall scaffolds,and micro needles,are presented.

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