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World Journal of Gastroenterology 2005年第47期11卷 7480-7485页

作者： Raquel Hernández Esther Martínez-Lara Ana cauelo Ma Luisa del Moral Santos Blanco Eva Siles Ana Jiménez Juan ngel pedrosa Ma ngeles peinado Department of Experimental Biology University of JaénParaje Las Lagunillas s/nE-23071 JaénSpain

AIM： To analyze the relationship between perisinusoidal stellate cell （pSC） activation and the dietary fat quantity and composition in the treatment of hepatic steatosis. METHODS： Using an experimental rat model of steatosis based on the intake of a hyperlipidic diet （14% fat as olive oil or sunflower oil, HL-O and HL-S, respectively）, we analyzed the liver＇s capability of recovery after the treatment with a normal-lipidic diet （5% fat as olive oil or sunflower oil, NL-O and NL-S, respectively） by immunoo/tochemical and Western blot analysis of glial fibrillary acidic protein （GFAp） expression in pSCs, collagen quantification and serum aminotransferase determination. RESULTS： The fatty infiltration in the steatotic livers decreased after the treatment with both NL diets, indicating liver recovery. This decrease was accompanied with a lower collagen deposition and aminotransferase level as well as changes in the pSC population that increased the GFAp expression. The above-mentioned effects were more pronounced in animals fed on NL-O based diet. CONCLUSION： Treatment with a balanced diet enriched in olive oil contributes to the liver recovery from a steatotic process. The pSC phenotype is a marker of this hepatic-recovery model.

关键词： pSCs GFAp Steatosis Collagen, Hyperlipidic diet Liver recovery Olive oil

健脾益气方配合早期肠内营养对结直肠癌术后患者胃肠功能及血清miR-19a、TNF-α、IL-6水平的影响

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世界中西医结合杂志 2018年第10期13卷 1414-1418页

作者：田军军陶然曹才望夏绍友李晨湖北省中医院普通外科湖北武汉430061 湖北省中医药研究院普通外科湖北武汉430074 中国人民解放军总医院普通外科北京100853

目的观察健脾益气方配合早期肠内营养对结直肠癌术后患者胃肠功能及血清miR-19a、肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)水平的影响。方法选取拟行结直肠癌手术患者102例作为研究对象,按照随机数字表法分为观察组和对照组各51例... 详细信息

目的观察健脾益气方配合早期肠内营养对结直肠癌术后患者胃肠功能及血清miR-19a、肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)水平的影响。方法选取拟行结直肠癌手术患者102例作为研究对象,按照随机数字表法分为观察组和对照组各51例。两组均给予健康教育、饮食、运动等基础干预,在此基础上对照组给予早期肠内营养,观察组在对照组基础上配合健脾益气方治疗。观察两组中医证候积分、临床疗效、血清白蛋白(ALB)、前白蛋白(pA)、转铁蛋白(TF)、CD3+、CD4+、CD8+、CD4+/CD8+水平、胃肠功能以及血清miR-19a、TNF-α、IL-6水平。结果治疗后两组中医证候积分显著低于治疗前(p p pA、TF显著高于治疗前(p p p pp p pp p p <0. 05)。结论健脾益气方配合早期肠内营养能够有效改善结直肠癌术后患者胃肠功能,降低血清miR-19a、TNF-α、IL-6水平。

关键词：健脾益气方肠内营养结直肠癌胃肠功能

Geochemistry and petrogenesis of the paleoproterozoic orthogneisses and granitoids of the Banded Gneissic Complex,central Rajasthan,NW India:Implications for crustal reworking processes

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Acta Geochimica 2023年第2期42卷 373-386页

作者： Iftikhar Ahmad T.p.Abdul Latheef M.E.A.Mondal Ismail S.Hamidullah Kamaal parvez Department of Geology Aligarh Muslim UniversityAligarhU.P 202002India Department of Earth Sciences Indian Institute of Technology RoorkeeRoorkee 247667India

Granitoids and orthogneisses(1.7 Ga)from the northern part of the Banded Gneissic Complex(BGC-II domain),Aravalli Craton(NW India)are geochemically analyzed to understand the geodynamic condition and crustal evolution *** samples are metaluminous to peraluminous(molar A/CNK:0.74±2.12),and characterized by Eu-anomaly ranging from 0.17 to 1.06,Fe_(2)O_(3)^(T)/(Fe_(2)O_(3)^(T)+MgO)from 0.8 to 0.9 and high magmatic zircon saturation temperature(>830°C)which are the features suggestive of A-type granite *** discrimination diagrams classify the samples as post-collisional extensional A2-type *** characteristics along with trace element ratios[(Y/Nb)_(N)=0.15 to 4.33(avg.0.76),(Th/Nb)_(N)=4.63 to 255.47(avg.63.13),(Th/ta)_(N)=1.37 to 9.84(avg.8.86),(Ce/pb)_(N)=0.05 to 3.05(avg.1.43)]indicate that the rocks were derived from a plagioclase-rich and garnet-free crustal source under lowpressure ***,it is also proposed that tonalite-trondhjemite-granodiorite(TTG)rocks which occur dominantly in southern Rajasthan(BGC-I)are precursors and their partial melting led to the generation of the studied A-type granite *** studied samples also bear close geochemical similarity with A-type granites of similar age(1.7 Ga)near the Sakhun-Ladera region of northern *** studied A-type granites are believed to be coeval to similar aged A-type granites of the Khetri and Alwar sub-basins of the North Delhi Fold Belt(NDFB).They are comparable in age and magmatic history to recorded A-type magmatism in North America and parts of the Chinese *** large geographical extents of synchronous A-type granites are proposed to be related to the Columbia Supercontinent assembly(ca.1.7 Ga;postcollisional granites).Thus,based on the studied extensional granites,we surmise that BGC-II was part of the Columbia Supercontinent.

关键词： Banded Gneissic Complex(BGC II) Aravalli Craton A-type granites Orthogneisses Rifting of Columbia

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四川省盐源县盐泉的特征与形成

现代地质 2020年第1期34卷 177-188页

作者：李娜周训郭娟拓明明徐艳秋中国地质大学(北京)水资源与环境学院北京100083 中国地质大学(北京)地下水循环与环境演化教育部重点实验室北京100083

研究天然盐泉的形成有助于揭示陆地水文循环过程中的物质迁移。采用水文地球化学的方法,分析四川省盐源县的9个泉水和卤水水样的水化学特征和同位素特征,探讨盐泉的溶质来源,总结盐泉的成因模式。水样可以分为TDS为311.69 g/L的Cl-Na型... 详细信息

研究天然盐泉的形成有助于揭示陆地水文循环过程中的物质迁移。采用水文地球化学的方法,分析四川省盐源县的9个泉水和卤水水样的水化学特征和同位素特征,探讨盐泉的溶质来源,总结盐泉的成因模式。水样可以分为TDS为311.69 g/L的Cl-Na型卤水、TDS为55.77~89.43 g/L的Cl-Na型盐泉、TDS为1.17 g/L的Cl-Na型微咸泉和TDS为0.26~0.56 g/L的以HCO3-ca、HCO3·SO4-ca·Mg型为主的淡水泉。泉水和卤水的氢氧同位素显示其来源于大气降水;水样的特征系数显示盐泉和卤水都属于溶滤型,且指示研究区基本不具有找钾前景。泉水的盐分主要来源于石盐、方解石、石膏和白云石等矿物的溶滤。盐泉的形成模式可以概括为:在山区获得大气降水入渗补给后,地下水经历较浅和较深的地下径流并且溶滤含盐地层或者盐矿,使其矿化度升高,在地形较低处汇集出露地表成泉。

关键词：盐泉卤水水化学成因四川

parylene C单体的合成及其结构解析

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材料导报 2010年第12期24卷 40-42,49页

作者：牛磊肖国民塔娜童洋东南大学化学化工学院南京211189

采用霍夫曼消除反应合成了parylene C单体(C16H14Cl2),改进了合成工艺,收率达到50%左右,并分析了其合成反应机理。采用溶液法合成了单晶,经IR及X射线单晶衍射表征,其结构属于单斜晶系,空间群为p21/C,晶胞参数a=0.79915nm,b=0.77202(15)n... 详细信息

采用霍夫曼消除反应合成了parylene C单体(C16H14Cl2),改进了合成工艺,收率达到50%左右,并分析了其合成反应机理。采用溶液法合成了单晶,经IR及X射线单晶衍射表征,其结构属于单斜晶系,空间群为p21/C,晶胞参数a=0.79915nm,b=0.77202(15)nm,c=1.0857(2)nm,β=103.65(3)°,V=0.6509(2)nm3,Z=2,Dx=1.414mg/m3,μ=0.48mm-1,R1=0.052,wR2=0.129,S=1.09。化合物的分子结构呈中心对称,桥头键长分别为0.1554(3)nm、0.1555(3)nm。由于C4位取代基的存在,产生了一个123.4(3)°的C2-C4-C7扭曲角。

关键词： paryleneC单体霍夫曼消除反应单斜晶系桥头键

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安徽贵池铜山铜矿成矿地质条件及矿床成因

中国有色金属学报 2012年第3期22卷 827-836页

作者：赵晓霞戴塔根张宇李品杰刘忠法中南大学有色金属成矿预测教育部重点实验室长沙410083 中南大学地球科学与信息物理学院长沙410083 铜陵有色金属集团控股有限公司铜山铜矿铜陵247127

从地层、构造、岩浆岩与成矿的关系入手,对本区成矿地质条件进行分析,指出石炭系中上统黄龙组和船山组为矿区最主要的赋矿层位,其灰岩岩性是形成接触交代矿床的最有利的岩性,且与泥盆系上统五通组和二叠系上统砂页岩构成了构造薄弱面—... 详细信息

从地层、构造、岩浆岩与成矿的关系入手,对本区成矿地质条件进行分析,指出石炭系中上统黄龙组和船山组为矿区最主要的赋矿层位,其灰岩岩性是形成接触交代矿床的最有利的岩性,且与泥盆系上统五通组和二叠系上统砂页岩构成了构造薄弱面——钙硅界面,有利于矿液的运移和矿质的沉淀;五通组石英砂岩为矿体定位起隔挡屏蔽作用;断裂构造F1为矿液运移、矿体定位的关键因素;燕山期的岩浆活动为成矿提供了物质来源、成矿流体和热能,是成矿的第一要素。在此基础上,结合本区成矿物质来源、形成条件、控矿因素、矿化形式以及成矿作用等方面的特征,对铜山铜矿的矿床成因进行了探讨,认为铜山铜矿包括多种矿化成因类型,整体上属以矽卡岩型成矿作用为主的燕山期岩浆热液铜铁金硫成矿系列。

关键词：成矿地质条件成矿过程矿床成因铜山铜矿

Nutritive value of introduced bamboo species in the northwestern Himalayas, India

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Journal of Forestry Research 2019年第6期30卷 2051-2060页

作者： D.R.Bhardwaj p.Sharma R.Bishist M.R.Navale R.Kaushal Dr.Y.S.parmar University of Horticulture and Forestry Solan 173 230India IcaR-Indian Institute of Soil and Water Conservation DehradunUttarakhandIndia

Bamboos are used extensively for a variety of purposes,and many new species have been introduced to the northwestern ***,their potential as a fodder species has not been *** bamboo species,namely Dendrocalamus hamiltonii Gamble,Dendrocalamus asper(*** Schult.f.)Backer ex ***,Melocanna baccifera(Roxb.)Kurz,phyllostachys aurea Rivie′re and ***′re,phyllostachys bambusoides Sieb and *** phyllostachys pubescens(pradelle)Mazel ex *** evaluated for their nutritional value,relative palatability and best lopping *** matter(DM),ether extract(EE),and crude fibre varied from(37.0-67.7)%,(4.7-7.6),and(22.1-37.9)%,*** of crude protein ranged from(12.2-17.1)%,total ash(ta)from(11.8-21.5)%,acid insoluble ash(AIA)from(0.3-0.5)%,nitrogen free extract from(31.1-40.8)%,carbohydrates from(57.0-69.0)%,organic matter(OM)from(78.5-88.2)%,calcium from(1.7-2.3)%,phosphorus from(0.4-0.8)%,potassium from,(0.9-1.6)%,magnesium from(0.5-0.9)%,sodium from(603.7-1072.7)×10^-6 and vitamin A from(21.1-30.5)×10^-2 mg/g,*** had maximum values for DM,EE,ta and *** and vitamin A were highest in *** and carbohydrates were maximized in *** and Cp in *** the values obtained for different bamboo species were less than maximum tolerable concentration of common feed resources of the region thereby indicating their suitability for nutrition and *** contents of anti-nutritional factors,namely hydrocyanic acid and tannin ranged from(33.8-61.7)×10^-2 mg/g and(0.7-1.9)%,*** was the best species from a palatability point of view and has maximum crude protein content(17.2%),ca(2.3%)and lowest tannin content(0.7%).The relative palatability of introduced bamboo species followed trend:***(97.6%)[***(92.5%)[***(81.2%)[***(76.9%)[***(75.9%)[***(73.4%).The optimum months for lopping these species for green leaves are Novem

关键词： Anti-nutritional values Nutritional values Bamboo Chemical composition Mineral nutrients palatability Lopping time

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添加糖与儿童心血管病风险的关系

中华高血压杂志 2016年第10期24卷 937-937页

作者：刘莉叶鹏 Vos MB Kaar JL Welsh ja Van Horn LV Feig DI Anderson ca patel MJ Cruz Munos J Krebs NF Xanthakos SA Johnson RK American Heart Association Nutrition Committee of the Council on Lifestyle and cardiometabolic Health Council on Clinical cardiology Council on Cardiovascular Disease in the Young Council on cardiovascular and Stroke Nurs-ing Council on Epidemiology and Prevention Council on Func-tional Genomics and Translational Biology Council on Hypertension

不良的生活方式行为是导致全球可预防疾病的原因。膳食中添加糖可使其富含能量但营养差,且可增加发展为肥胖、心血管病、高血压、肥胖相关的癌症和龋齿的风险。方法和结果：美国心脏协会对目前的科学证据进行审查和分级,探讨添加糖对儿... 详细信息

不良的生活方式行为是导致全球可预防疾病的原因。膳食中添加糖可使其富含能量但营养差,且可增加发展为肥胖、心血管病、高血压、肥胖相关的癌症和龋齿的风险。方法和结果：美国心脏协会对目前的科学证据进行审查和分级,探讨添加糖对儿童心血管健康的影响。

关键词：心血管病风险儿童糖美国心脏协会心血管健康预防疾病生活方式

冀南符山铁矿床成因研究:来自流体包裹体和H、O、S同位素证据

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矿物岩石地球化学通报 2022年第4期41卷 837-848页

作者：息朝庄杜高峰戴塔根邓会娟湖南城市学院土木工程学院湖南益阳413000 城市地下基础设施结构安全与防灾湖南省工程研究中心湖南益阳413000 东华理工大学数字国土江西省重点实验南昌330013 中南大学地球科学与信息物理学院长沙410083 自然资源实物地质资料中心河北燕郊065201

符山铁矿位于冀南邯邢地区、符山岩体中南部,矿体呈“入”字型、似层状、透镜体赋存于中奥陶统碳酸盐岩中。为厘清其成因,对矿床中主要矿物进行了流体包裹体和H、O、S同位素分析研究。结果显示,从干矽卡岩期至湿矽卡岩期,流体包裹体的... 详细信息

符山铁矿位于冀南邯邢地区、符山岩体中南部,矿体呈“入”字型、似层状、透镜体赋存于中奥陶统碳酸盐岩中。为厘清其成因,对矿床中主要矿物进行了流体包裹体和H、O、S同位素分析研究。结果显示,从干矽卡岩期至湿矽卡岩期,流体包裹体的均一温度大多为510~310℃;流体包裹体液相成分以K^(+)、Na^(+)、ca^(2+)与Mg^(2+),SO_(4)^(2-)、Cl^(-)与F^(-)为主;气相成分以H_(2)O、CO_(2)与CH_(4)为主。符山铁矿黄铁矿的δ^(34)S值为6.3‰~8.6‰,磁铁矿的δ^(18)O值为5.7‰~7.8‰,流体包裹体的δD值为-78‰~-83‰。研究认为,符山铁矿成矿物质来源于壳幔混合源,成矿流体为K-Na-ca-Mg-SO_(4)-Cl-F的中高温度、中高盐度的流体,来源于建造水和大气降水;成矿流体上升过程中与中奥陶统的膏盐层发生反应后沉淀形成矽卡岩型矿床。

关键词：符山铁矿床流体包裹体 H、O、S同位素矿床成因冀南

An inter-laboratory study of DNA-based identity,parentage and species testing in animal forensic genetics

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Forensic Sciences Research 2022年第4期7卷 708-713页

作者： Sreetharan Kanthaswamy Torsten Brendel Luis cancela Denise A.Andrade de Oliveira Bertram Brenig carmen Cons Julian A.Crespi Markéta Dajbychová Andreas Feldl Tomohito Itoh Vincenzo Landi Amparo Martinez Malgorzata Natonek-Wisniewska Robert F.Oldt Anna Radko Oscar Ramírez Clementina Rodellar Manuel Ruiz-Girón David Schikorski María Elena Turba Guillermo Giovambatista School of Mathematics and Natural Sciences Arizona State University(ASU)at the West CampusGlendaleAZUSA california National primate Research Center University of CaliforniaDavisCAUSA Evolutionary Biology Graduate program School of Life SciencesArizona State UniversityTempeAZUSA Eurofins Genomics Europe Applied Genomics GmbH EbersbergGermany IDENTItaS MontevideoUruguay Laboratório de Genética Escola de Veterinária da UFMGBelo HorizonteBrazil Institute of Veterinary Medicine University of GoettingenGoettingenGermany Facultad de Veterinaria Laboratorio de Genética Bioquímica(LAGENBIO)Instituto Agroalimentario de Aragón-IA2(Universidad de Zaragoza-CITA)ZaragozaSpain Facultad de Ciencias Veterinarias UNLp IGEVET-Instituto de Genética Veterinaria(UNLP-CONICET LAPLATA)La PlataArgentina Genomia s.r.o. PlzeňCzech Republic Maebashi Institute of Animal Science Livestock Improvement Association of Japan(LIAJ)MaebashiJapan Department of Veterinary Medicine Animal Breeding and GeneticsUniversity of Bari“Aldo Moro”ValenzanoItaly Department of Genetics Faculty of Veterinary SciencesUniversity of CórdobaCórdobaSpain Department of Animal Molecular Biology National Research Institute of Animal ProductionBalicePoland Vetgenomics SL BarcelonaSpain Laboratorio de Biología Molecular y Genómica Hispalis Biolab S.L.U.SevilleSpain Laboratoire LABOFARM-GENINDEXE LOUDEACCedexFrance Genefast SRL ForlìItaly

The probative value of animal forensic genetic evidence relies on laboratory accuracy and ***-laboratory comparisons allow laboratories to evaluate their performance on specific tests and analyses and to continue to monitor their *** International Society for Animal Genetics(ISAG)administered animal forensic comparison tests(AFCTs)in 2016 and 2018 to assess the limitations and capabilities of laboratories offering forensic identification,parentage and species determination *** AFCTs revealed that analyses of low DNA template concentrations(≤300 pg/μL)constitute a significant challenge that has prevented many laboratories from reporting correct identification and parentage ***,a lack of familiarity with species testing protocols,interpretation guidelines and representative databases prevented over a quarter of the participating laboratories from submitting correct species determination *** laboratories showed improvement in their genotyping accuracy over ***,the use of forensically validated standards,such as a standard forensic short tandem repeat(STR)kit,preferably with an allelic ladder,and stricter guidelines for STR typing,may have prevented some common issues from occurring,such as genotyping inaccuracies,missing data,elevated stutter products and loading *** AFCTs underscore the importance of conducting routine forensic comparison tests to allow laboratories to compare results from each *** should keep improving their scientific and technical capabilities and continuously evaluate their personnel’s proficiency in critical techniques such as low copy number(LCN)analysis and species *** this is the first time that the ISAG has conducted comparison tests for forensic testing,findings from these AFCTs may serve as the foundation for continuous improvements of the overall quality of animal forensic genetic testing.

关键词： Forensic sciences forensic genetics comparison test forensic DNA analysis individual identification parentage test species test