检索结果-南通市图书馆

Evaluation of a traditional method for peak flow discharge estimation for floods in the Wenchuan Earthquake area,Sichuan Province,China

在线全文

学校读者我要写书评

暂无评论

Journal of Mountain Science 2019年第3期16卷 641-656页

作者： GUO Xiao-jun cui Peng li Yong liu jin-feng GE Yong-gang WANG Ci-de Key Laboratory of Mountain Surface Process and Hazards/Institute of Mountain Hazards and Environment Chinese Academy of Sciences Center for Excellence in Tibetan Plateau Earth Sciences Chinese Academy of Sciences Aba Hydrological and Water Resources Survey Bureau of Sichuan Province

Peak discharge of flood in small mountainous watershed is usually calculated using the "Rainstorm–runoff calculation method in small watersheds in Sichuan Province"(RRM). This study evaluated the RRM calculation using real-time monitored rainfall and hydrologic data from a small watershed in the Wenchuan Earthquake area of Sichuan Province, China. The results indicated that the discharge values given by the RRM are commonly overestimating the measured discharge. The overestimation rate was discussed and empirical equations were proposed for improving RRM estimations, based on the relationship between calculated and measured discharge values at different watershed scales(2, 30, and 40 km2), under different rainfall probabilities(0.97–0.5, 0.5–0.2, and 0.2–0.002), and for different rainfall durations(0–6, 6–24, and >24 h). The results of this study help contribute to the understanding of water floods formation and help provide more accurate estimations of peak flow discharge in small watersheds in the Wenchuan Earthquake area.

关键词： Rainfall Runoff yield Influx Peak discharge Wenchuan Earthquake area

Factors underlying the association of body mass index with serum ALT in Chinese hypertensive adults without known hepatic diseases

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2013年第8期14卷 743-748页

作者： Yan ZHANG Xian-hui QIN jian-ping li Yi-min cui Ze-yuan liu Zhi-gang ZHAO jun-bo GE De-ming GUAN jian HU Yan-ni WANG Fu-min ZHANG Xin XU Xi-ping XU Yong HUO Department of Cardiology Peking University First Hospital Division of Nephrology Nanfang Hospital Southern Medical University Department of Clinical Pharmacology Peking University First Hospital Department of Pharmacy the First Affiliated Hospital of Academy of Military Medical Sciences of China Department of Pharmacy Beijing Tiantan Hospital Capital Medical University Department of Cardiology Zhongshan Hospital Fudan University Department of Cardiology the First Clinical Medical College of Harbin Medical University Department of Cardiology the First Affiliated Hospital of China Medical University Department of Cardiology the First Affiliated Hospital of School of Medicine Xi'an Jiaotong University Department of Cardiology the First Affiliated Hospital of Nanjing Medical University Guangdong Institute of Nephrology Southern Medical University

Objective： High body mass index （BMI） is considered as the most important risk factor for elevated serum alanine aminotransferase （ALT） concentration. This study examined an array of factors, including waist circumference （WC） and folate deficiency, which may mediate the association of BMI with serum ALT concentration in Chinese hypertensive adults without known hepatic diseases. Methods： A multicenter, cross-sectional study was carried out. A total of 378 patients with mild or moderate hypertension and without known hepatic diseases were recruited from five hospitals in Harbin, Shanghai, Beijing, Xi＇an, and Nanjing. Results： Of the 360 hypertensive patients with complete data in our final analysis, 13.6% had high ALT concentrations （〉40 IU/L）. Factors including BMI, WC, triglycedde level, and folate concentration were associated with ALT concentration in univariate analysis. Consistently higher preva- lence rates of elevated ALT were observed in subjects with lower folate concentrations （≥12 vs. 〈12 nmol/L, 9.9% vs. 17.8%, P=-0.03）, with higher BMI （≥28 vs. 〈28 kg/m2, 21.5% vs. 11.4%, P=-0.02） or higher WC （≥90 vs. 〈90 cm, 18.5% vs. 10.0%, P=-0.02）. However, in multivariate analysis, the association between BMI and ALT concentration disap- peared （P=-0.802 in males and 0.369 in females）, while WC in females （P〈0.001） and folate concentration （P=-0.036 in males and 0.044 in females） remained as significant predictors for ALT concentration. Conclusions： This multicenter study demonstrated that WC and low folate concentration were important factors underlying the association between BMI and ALT concentrations in Chinese hypertensive adults without known hepatic diseases.

关键词： Alanine aminotransferase (ALT) Body mass index (BMI) Waist circumference (WC) Folate

Analysis of Health Service Utilization and its Influencing Factors among Patients with Pneumoconiosis in China

在线全文

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2021年第1期34卷 83-88页

作者： WANG Huan Qiang JIA jun lin jianG Zhao Qiang jin Qi li Dong Xia liNG Rui Jie li Ying cui ping CHEN gang ZHAO Hong Yu li Yan WEN Ke LYU Xiang Pei LOU jian lin li Tao National Institute of Occupational Health and Poison Control Chinese Center for Disease Control and PreventionBeijing 100050China Hangzhou Medical College(Zhejia ng Academy of Medical Sciences) Hangzhou 310013ZhejiangChina Center for Clinical Big Data and Analytics The Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009ZhejiangChina Guizhou Hospital for Occupational Disease Prevention and Control Guiyang 550006GuizhouChina Hubei Hospital for Occupational Diseases Wuhan 430000HubeiChina Hunan Prevention and Treatment Center for Occupational Disease Changsha 410007HunanChina Shandong Academy of Occupational Health and Occupational Medicine Jinan 250062ShandongChina Beidaihe Hospital for Occupational Disease Prevent on and ControlState Administration of Production SafetyQinhuangdao 066100HebeiChina Yunnan Hospital for Occupational Diseases Kunming 650011YunnanChina Jilin Hospital for Occupational Disease Prevention and Control Changchun 132000JilinChina

Pneumoconiosis,an interstitial lung disease that occurs from breathing in certain kinds of damaging dust particles,is a major occupational disease in *** diagnosed with occupational pneumoconiosis can avail of free medical treatment,whereas patients without a diagnosis of occupational diseases cannot not claim free medical treatment in most provinces from the government before *** study aimed to analyze the priority of medical facility selection and its influencing factors among patients with pneumoconiosis.

关键词： diagnosis treatment among

Inetetamab combined with S-1 and oxaliplatin as first-line treatment for human epidermal growth factor receptor 2-positive gastric cancer

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第40期30卷 4367-4375页

作者： Ying Kong Qi Dong Peng jin Ming-Yan li li Ma Qi-jun Yi Yu-E Miao Hai-Yan liu jian-gang liu Department of Oncology The Second Affiliated Hospital of Shandong First Medical UniversityTai’an 271000Shandong ProvinceChina Department of Gastrointestinal Surgery The Second Affiliated Hospital of Shandong First Medical UniversityTai’an 271000Shandong ProvinceChina

BACKGROUND Patients with human epidermal growth factor receptor 2(HER2)-positive advanced gastric cancer have poor *** combined with chemotherapy is the first-line standard treatment for HER2-positive advanced gastric *** is a novel anti-HER2 drug,and its efficacy and safety in gastric cancer have not yet been *** To evaluate the efficacy and safety of the S-1 plus oxaliplatin(SOX)regimen combined with inetetamab as a first-line treatment for HER2-positive advanced gastric *** Thirty-eight patients with HER2-positive advanced gastric cancer or gastroeso-phageal junction adenocarcinoma were randomly divided into two groups:One group received inetetamab combined with the SOX regimen,and the other group received trastuzumab combined with the SOX *** 4-6 cycles,patients with stable disease received maintenance *** primary endpoints were progression-free survival(PFS)and overall survival(OS),and the secondary endpoints were the objective response rate,disease control rate,and adverse events(AEs).RESULTS Thirty-seven patients completed the trial,with 18 patients in the inetetamab group and 19 patients in the trastuzumab *** the inetetamab group,the median PFS was 8.5 months,whereas it was 7.3 months in the trastuzumab group(P=0.046);this difference was *** median OS in the inetetamab group vs the trastuzumab group was 15.4 months vs 14.3 months(P=0.33),and the objective response rate was 50%vs 42%(P=0.63),respectively;these differences were not *** AEs included leukopenia,thrombocytopenia,nausea,and *** incidence rates of grade≥3 AEs were 56%in the inetetamab group and 47%in the trastuzumab group(P=0.63),with no significant *** In the first-line treatment of HER2-positive advanced gastric cancer,inetetamab and trastuzumab showed comparable *** inetetamab group showed superior PFS,and both groups had good safety.

关键词： Human epidermal growth factor receptor 2-positive Advanced gastric cancer Inetetamab Trastuzumab Efficacy Safety

Influence of Precursor Powder Fabrication Methods on the Superconducting Properties of Bi-2223 Tapes

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics Letters 2019年第2期36卷 59-63页

作者： li-jun cui ping-Xiang Zhang Guo Yan Yong Feng Xiang-Hong liu jian-Feng li Xi-Feng Pan Sheng-Nan Zhang Xiao-Bo Ma jin-Shan li State Key Laboratory of Solidification Processing Northwestern Polytechnical University National Engineering Laboratory for Superconducting Materials Western Superconducting Technologies Co.Ltd. Superconducting Materials Center Northwest Institute for Nonferrous Metal Research

Bi-2223 precursor powders are prepared by both oxalate co-precipitation(CP) and spray pyrolysis(SP) *** influence of fabrication methods on the superconducting properties of Bi-2223 tapes are systematically studied. Compared to the CP method, SP powder exhibits spherical particle before calcination and smaller particle size after calcinations with more uniform chemical composition, which leads to a lower reaction temperature during calcination process for Bi-2223 tapes. Meanwhile, the non-superconducting phases in SP powder are more uniformly distributed with smaller particle sizes. These features result in finer homogeneity of critical current in large-length of Bi-2223 tape, higher density of filaments and better texture after heat treatment. Therefore,the SP method could be considered as a better route to prepare precursor powder for large-length Bi-2223 tape fabrication.

关键词： Precursor Powder Fabrication Methods Superconducting Properties Bi-2223 Tapes

Spherical nanoindentation stress–strain responses of SIMP steel to synergistic effects of irradiation by H and He ions

在线全文

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2022年第6期33卷 139-147页

作者： Peng jin Tie-Long Shen jing li Yu-Shan Yang jian-Long Chai Ya-Bin Zhu Ming-Huan cui Chao liu Tong-Min Zhang Long Kang jun li jin-Yu li Shuo-Xue jin Xing-Zhong Cao Zhi-Guang Wang Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China

A novel Fe-10Cr ferritic/martensitic steel called SIMP was chosen to investigate synergistic effects of H and He on the mechanical properties of structural materials for innovative nuclear energy systems. Sequential and separate irradiation experiments on SIMP steel specimens at room temperature using H and He ions with various energy levels were conducted to produce an ion deposition plateau at 300-650 nm. The indentation stress-strain responses were examined using spherical nanoindentation tests after the irradiation experiments. It was found that the sequential irradiation by He and H produced a higher indentation yield stress than separate irradiation, indicating that the hardening was enhanced by the synergy of the H and He irradiation. The micro-mechanism responsible for enhancing the hardening of the SIMP steel through the H and He synergy was investigated using Doppler broadening spectroscopy detection and transmission electron spectroscopy observations.

关键词： H/He irradiation Spherical nanoindentation Bubbles Dislocation loops

Recent progress in nuclear astrophysics research and its astrophysical implications at the China Institute of Atomic Energy

在线全文

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2024年第12期35卷 376-408页

作者： Wei-ping liu Bing Guo Zhu An Bao-Qun cui Xiao Fang Chang-Bo Fu Bin-Shui Gao jian-jun He Yu-Chen jiang Chong Lv Er-Tao li Ge-Xing li Yun-Ju li Zhi-Hong li gang lian Wei-ping lin Yi-hui liu Wei Nan Wei-Ke Nan Yang-ping Shen Na Song jun Su liang-Ting Sun Xiao-Dong Tang Luo-Huan Wang Shuo Wang You-Bao Wang Di Wu Xiao-Feng Xi Sheng-Quan Yan li-Yong Zhang China Institute of Atomic Energy Beijing 102413China Department of Physics Southern University of Science and TechnologyShenzhen 518055China jinping Deep Underground Frontier Science and Dark Matter Key Laboratory of Sichuan Province Liangshan 615000China School of Physics Xi’an Jiaotong UniversityXi’an 710049China Key Laboratory of Radiation Physics and Technology of the Ministry of Education Institute of Nuclear Science and TechnologySichuan UniversityChengdu 610064China Sino-French Institute of Nuclear Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China Key Laboratory of Nuclear Physics and Ion-beam Application(MoE) Institute of Modern PhysicsFudan UniversityShanghai 200433China Joint Department for Nuclear Physics Institute of Modern PhysicsChinese Academy of Sciences and Lanzhou UniversityLanzhou 730000China CAS Key Laboratory of High Precision Nuclear Spectroscopy Institute of Modern PhysicsChinese Academy of SciencesLanzhou 73000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China Key Laboratory of Beam Technology of Ministry of Education College of Nuclear Science and TechnologyBeijing Normal UniversityBeijing 100875China College of Physics and Optoelectronic Engineering Shenzhen UniversityShenzhenChina Key Laboratory of Beam Technology and Material Modification of Ministry of Education College of Nuclear Science and TechnologyBeijing Normal UniversityBeijing 100875China Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China School of Mathematics and Physics Handan UniversityHandan 056005China Shandong Provincial Key Laboratory of Optical Astronomy and Solar-Terrestrial Environment Institute of Space SciencesShandong UniversityWeihai 264209China State Key Laboratory of Nuclear Physics and Technology School of PhysicsCAPTPeking UniversityBeijing 100871China

Nuclear astrophysics is a rapidly developing interdisciplinary feld of research that has received extensive attention from the scientifc community since the midtwentieth ***,it uses the laws of extremely small atomic nuclei to explain the evolution of the *** to the complexity of nucleosynthesis processes and our limited understanding of nuclear physics in astrophysical environments,several critical astrophysical problems remain *** achieve a better understanding of astrophysics,it is necessary to measure the cross sections of key nuclear reactions with the precision required by astrophysical *** measurement of nuclear reaction cross sections is an important method of investigating how nuclear reactions infuence stellar *** the challenges involved in measuring the extremely low crosssections of nuclear reactions in the Gamow peak and preparing radioactive targets,indirect methods,such as the transfer reaction,coulomb dissociation,and surrogate ratio methods,have been developed over the past several *** are powerful tools in the investigation of,for example,neutron-capture(n,r)reactions with short-lived radioactive ***,direct measurement is still preferable,such as in the case of reactions involving light and stable *** an essential part of stellar evolution,these low-energy stable nuclear reactions have been of particular interest in recent *** overcome the diffculties in measurements near or deeply within the Gamow window,the combination of an underground laboratory and high-exposure accelerator/detector complex is currently the optimal ***,underground experiments have emerged as a new and promising direction of *** addition,to better simulate the stellar environment in the laboratory,research on nuclear physics under laser-driven plasma conditions has gradually become a frontier *** recent years,the CIAE team conducted a series of distinctive nuclea

关键词： Nuclear astrophysics Indirect method Underground laboratory Direct measurement Lowenergy nuclear reaction

Genetic Diversity, Antimicrobial Resistance, and Virulence Genes of Aeromonas Isolates from Clinical Patients, Tap Water Systems, and Food

在线全文

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2020年第6期33卷 385-395页

作者： MENG Shuang WANG Yong Lu liu Chen Geng YANG jing YUAN Min BAI Xiang Ning jin Dong liANG jun Rong cui Zhi gang li Juan State Key Laboratory of Infectious Disease Prevention and Control National Institute for Communicable Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing 10026China Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases Zhejiang 310058HangzhouChina Ma'anshan Center for Disease Control and Prevention Ma'anshan 243031AnhuiChina Clinical Laboratoty of Xuanwu Hospital Captital Medcial University'Beijing 100053China

Objective This study aimed to evaluate the genetic diversity,virulence,and antimicrobial resistance of Aeromonas isolates from clinical patients,tap water systems,and *** Ninety Aeromonas isolates were obtained from Ma’anshan,Anhui province,China,and subjected to multi-locus sequence typing(MLST)with six housekeeping *** taxonomy was investigated using concatenated gyr B-cpn60 sequences,while their resistance to 12 antibiotics was *** putative virulence factors and several resistance genes were identified by PCR and *** The 90 Aeromonas isolates were divided into 84 sequence types,80 of which were novel,indicating high genetic *** Aeromonas isolates were classified into eight different *** assays identified virulence genes in the isolates,with the enterotoxin and hemolysin genes act,aer A,alt,and ast found in 47(52.2%),13(14.4%),22(24.4%),and 12(13.3%)of the isolates,*** majority of the isolates(≥90%)were susceptible to aztreonam,imipenem,cefepime,chloramphenicol,gentamicin,tetracycline,and ***,several resistance genes were detected in the isolates,as well as a new mcr-3 *** Sequence type,virulence properties,and antibiotic resistance vary in Aeromonas isolates from clinical patients,tap water systems,and food.

关键词： Aeromonas Multi-locus sequence typing Multidrug resistance Virulence gene Antimicrobial resistance gene

A Prospective Randomized Multicenter Controlled Trial on Salvianolate for Treatment of Unstable Angina Pectoris in A Chinese Elderly Population

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Integrative Medicine 2019年第10期25卷 728-735页

作者： cui Hua li Xiao-ying GAO Xue-wen LU Xiang WU Xiu-ping WANG Xiao-fei ZHENG Xiang-qing HUANG Kui liu Feng LUO Zhi YUAN hui-shu SUN gang KONG jian DU Xiao-hong ZHENG jin liu Hong-ying ZHANG Wen-ju Department of Geriatric Cardiology the General Hospital of the People's Liberation Army Beijing (100853) China the Second Department of Cardiology the Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine Harbin (150009) China Department of Cardiology Guizhou Province Hospital of Traditional Chinese Medicine Guiyang (550001) China Department of Cadre's Ward the First Bethune Hospital of Jilin University Changchun (130021) China Department of Cadre Health Care the First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang Province (325000) China Medical Department Shanghai Green Valley Pharmaceutical Co. Ltd. Shanghai (201203) China China Health Promotion Foundation Beijing (100161) China Department of Geriatric Clinic Inner Mongolia People's Hospital Hohhot (010017) China Department of Cardiology the Second Affiliated Hospital of Nanjing Medical University Nanjing (210011) China Second Department of Cadre's Ward the First Affiliated Hospital of Harbin Medical University Harbin (150001) China Department of Cadre Health Care Tianjin First Central Hospital Tianjin (300192) China Department of Cardiovascular Medicine Chongqing General Hospital Chongqing (400013) China Department of Geriatrics Shenyang Red Cross Hospital Shenyang (110063) China Department of Geriatric Cardiology Guangzhou First People's Hospital Guangzhou (510180) China Department of Cardiology Beijing Geriatric Hospital Beijing (100095) China

Objective: To evaluate the efficacy and safety of salvianolate in elderly patients with unstable angina pectoris(UAP). Methods: A prospective double-blind randomized placebo-controlled multicenter trial in elderly patients with UAP from 13 third-grade class-A hospitals in China was performed. A total of 318 patients were randomly allocated in a 1:1 ratio to an experimental group(160 patients) and a control group(158 patients). The experimental group was treated with salvianolate for 14 days on the basis of conventional medicine, and the control group was given a placebo for 14 days with the same criteria. Follow-up was lasted 28 days in both groups. The primary endpoint was biweekly frequency of angina pectoris attacks. The secondary endpoints included biweekly dosage of nitroglycerin, the Seattle Angina Questionnaire, angina pectoris severity and duration, myocardial injury markers, high-sensitivity C-reactive protein(hs-CRP) and N-terminal pro-B-type natriuretic peptide(NT-proBNP), as well as major adverse cardiovascular events(MACEs). Safety was assessed according to adverse events and serious adverse events. Results: Baseline characteristics were similar between treatment groups. Compared with those in the control group, the frequency of biweekly angi na attacks(2.92 vs. 4.08, P =0.025), th e biweekly dosage of nitroglycerin, as well as the severity and duration of angina attacks(P <0.01) were reduced by salvianolate. The Seattle Angina Questionnaire score was also significantly improved in the experimental group than in the control group(P <0.05). No significant differences were observed between the two groups with respect to the incidence of MACEs. Salvianolate was well tolerated. Conclusions: Salvianolate appear to have efficacy and well tolerated for elderly patients with UAP.

关键词： Salvianolate unstable angina pectoris elderly efficacy