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Unraveling the distribution patterns of near-surface temperature lapse rates in the Northwestern Kunlun Mountains

Journal of Mountain Science 2022年第4期19卷 1168-1181页

作者： SUN cong-jian CHEN Wei SHEN Yan-jun School of Geographical Science Shanxi Normal UniversityTaiyuan 030031China Key Laboratory of Agricultural Water Resources Center for Agricultural Resources ResearchInstitute of Genetics and Developmental BiologyChinese Academy of SciencesShijiazhuang 050021China

The near-surface temperature lapse rates for the core area of the Kunlun Mountains remain critically unresolved due to data ***,we revealed the spatial and temporal patterns of nearsurface temperature lapse rate in the Kunlun Mountain regions based on both long-term meteorological records(1961-2017)and field surveys measured data(2012-2017).The results showed that(1)The near-surface temperature lapse rates(β;)has spatiotemporal distribution patterns on the Northwestern Kunlun Mountains(NWKM),and in complex terrain areas the complexity of the temperature-elevation relationship cannot be explained by the constant environmental temperature lapse rate(0.65℃/100 m)throughout alone.(2)Theβ;for the daily mean,minimum,and maximum temperature on the north slopes in the Kunlun mountain area are 0.41,0.47,and 0.37℃/100 m and on the Tiznafu River(TR)basin are 0.51,0.47 and 0.53℃/100 m,respectively.(3)The variations ofβ;for daily maximum and minimum temperature of the two regions exhibit similar monthly characteristics,which are lower in the winter and spring months than in other months.A greatest variability ofβ;for the daily mean,minimum,and maximum temperature appears in winter and a light variability ofβ;occurs in *** seasonal variability ofβ;for daily maximum temperature is greater than that for daily minimum temperature,and the seasonal variability ofβ;for daily average temperature has the smallest variability.(4)There is no significant trend of change occurred in theβ;of NWKM.(5)The spatial and temporal variations ofβ;for the NWKM are linked to the geographic differences and climate *** results of Grey Relational Analysis showed that theβ;distribution is mainly influenced by the wind speed and relative humidity of the NWKM.

关键词： Near-surface Temperature Lapse Rate Spatiotemporal Variations Controlling Factors Northwestern Kunlun Mountains

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Computation model of proppant embedment depth based on dimensional analysis

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Journal of Coal Science & Engineering(China) 2013年第4期19卷 483-487页

作者： cong LU jian-Chun GUO State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum University Chengdu 610500China

Hydraulic fracturing is designed to form a high-conductivity fracture. The proppant will embed into the formation rock, especially in soft rock, owing to the interaction between proppant and fracture surface after fracture closure. Proppant embedment would reduce the fracture width and then lower the fracture conductivity. According to dimensional analysis, the rock is assumed to be an elastic material. Using the theory of elasticity to describe the stage of elastic deformation and analysis of the corresponding simplified embedding process, the study establish the static computation model of the two-dimensional infinite half plane and three-dimensional infinite half space model of the proppant embedment. According to laboratory results, the calculation model was modified, got an effective correction factor and analyzed the causes of errors, then discussed the factors which have impact on proppant embedment. The result calculated by the model in this paper can be reference of prop- pant optimization in on-site fracturing for a certainty degree.

关键词： proppant embedment dimension theory of elasticity experiment model

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Reshaping force for deformed casing repairing with hydraulic rolling reshaper and its influencing factors

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Petroleum Science 2024年第4期21卷 2745-2757页

作者： Hong-Fei Li Min Luo Ting-Ting Xu Qiao-Zhen Li cong-jian Huang School of Mechanical Science and Engineering Northeast Petroleum UniversityDaqing163318HeilongjiangChina

Hydraulic rolling reshaper is an advanced reshaping tool to solve the problem of casing deformation,which has been widely used in recent *** it is used for well repair operation,the reshaping force provided by ground devices is generally determined by ***,too large reshaping force may destroy the deformed casing,and too small reshaping force may also prolong the construction period and affect the repairing *** this paper,based on Hertz contact theory and elastic-plastic theory,combined with the process parameters of shaping,and considering the structural characteristics of the deformed casing and reshaper,we propose a mathematical model for calculating the reshaping force required for repairing deformed casing by hydraulic rolling ***,the finite element model and numerical method of hydraulic rolling reshaper repairing deformed casing are established by using the finite element method,and the reliability of the mathematical model is verified by several *** this basis,the control variable method is used to investigate the influence of each parameter on the reshaping force,and the influence degree of each parameter is explored by orthogonal simulation test and Pearson correlation *** research results not only provide an important theoretical basis for the prediction of reshaping force in on-site construction,but also provide a reference for the subsequent improvement of the shaping process.

关键词： Hydraulic rolling reshaper Reshaping force Deformed casing Casing reshaping Hertz contact theory

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Genetic relationships among sympatric varieties of Acer mono in the Chichibu Mountains and Central Hokkaido, Japan

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Journal of Forestry Research 2017年第4期28卷 699-704页

作者： Chunping Liu jian cong Hailong Shen Cunxue Lin Yoko Saito Yuji Ide State Key Laboratory of Forest Genetics and Breeding Northeast Forestry UniversityHarbin 150040China Foreign Capital Project Office Forestry Department of Liaoning ProvinceShenyang 110036China Mudanjiang Branch of Heilongjiang Academy of Agricultural Sciences Mudianjiang 157041China Laboratory of Forest Ecosystem Studies Department of Ecosystem StudiesGraduate School of Agriculture and Life ScienceThe University of TokyoYayoi 1-1-1Bunkyo-kuTokyo 113-8657Japan

Acer mono Maxim. is one of the major components of cool temperate forests in Japan. Some of its many varieties are distributed sympatrically. Because of its great variability, the intraspecific taxonomy and nomenclature of the species are controversial. To understand the genetic relationships among these varieties and whether hybridization or introgression occurred among the sympatric varieties, we studied the genetic relationships among sympatric varieties of A. mono in the Chichibu Mountains (A. mono var. ambiguum, A. mono var. connivens, A. mono var. marmoratum) and Central Hokkaido (A. mono var. mayrii and A. mono var. glabrum) in Japan. Our results showed that varieties in Chichibu are genetically close, suggesting that hybridization or introgression might occur between these varieties, which could explain the higher genetic diversity of varieties in Chichibu than in Hokkaido. In contrast to the close relationships between the varieties in Chichibu, varieties in Hokkaido seemed relatively separated from each other; indeed, there may be reproductive isolation between the two varieties. The results provide new insight for the taxonomy of the varieties of A. mono, especially the sympatric varieties, in Japan.

关键词： Genetic differentiation Hybridization Introgression Maple nSSR

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Changes in intrinsic excitability of ganglion cells in degenerated retinas of RCS rats

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International Journal of Ophthalmology(English edition) 2018年第5期11卷 756-765页

作者： Yi-Ming Ren Chuan-Huang Weng cong-jian Zhao Zheng-Qin Yin Southwest Hospital/Southwest Eye Hospital Third Military Medical University (Army Medical University) Key Lab of Visual Damage and Regeneration & Restoration of ChongqingChongqing 400038 China

AIM：To evaluate the intrinsic excitability of retinal ganglion cells（RGCs） in degenerated ***：The intrinsic excitability of various morphologically defined RGC types using a combination of patch-clamp recording and the Lucifer yellow tracer in retinal wholemount preparations harvested from Royal College of Surgeons（RCS） rats,a common retinitis pigmentosa（RP） model,in a relatively late stage of retinal degeneration（P90） were *** parameters of RGC morphologies and action potentials（APs） were measured and compared to those of non-dystrophic control rats,including dendritic stratification,dendritic field diameter,peak amplitude,half width,resting membrane potential,AP threshold,depolarization to threshold,and firing ***：Compared with non-dystrophic control RGCs,more depolarizations were required to reach the AP threshold in RCS RGCs with low spontaneous spike rates and in RCS OFF cells（especially A2o cells）,and RCS RGCs maintained their dendritic morphologies,resting membrane potentials and capabilities to generate ***：RGCs are relatively well preserved morphologically and functionally,and some cells are more susceptible to decreased excitability during retinal *** findings provide valuable considerations for optimizing RP therapeutic strategies.

关键词： retinal degeneration ganglion cell intrinsicexc itability patch clamp

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Prognostic value of soluble MICA levels in the serum of patients with advanced hepatocellular carcinoma

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Chinese Journal of Cancer 2013年第3期32卷 141-148页

作者： jian-Jun Li Ke Pan Mo-Fa Gu Min-Shan Chen Jing-Jing Zhao Hui Wang Xiao-Ting Liang jian-cong Sun jian-Chuan Xia State Key Laboratory of Oncology in South China Department of Experimental Research Department of Radiation Oncology Department of Hepatobilary Oncology Sun Yat-sen University Cancer Center

Serum levels of soluble MHC class I-related chain A (sMICA) are related with the prognosis of various types of cancer; however, few studies on the prognostic value of sMICA in hepatocellular carcinoma (HCC) have been reported. In this study, we retrospectively investigated the relationship between sMICA levels and clinical features of advanced HCC, and we assessed the prognostic value of sMICA in advanced HCC. Furthermore, the relationship of serum sMICA levels and natural killer group 2, member D (NKG2D) expression on natural killer (NK) cells was also evaluated. We detected sMICA levels in the serum of 60 advanced HCC patients using enzyme-linked immunosorbent assay (ELISA) and measured expression levels of NKG2D on NK cells using flow cytometry. We found that serum sMICA levels in HCC patients were in the range of 0.10 -6.21 ng/mL. Chi-square analyses showed that sMICA level was significantly related with only tumor size. Survival analysis showed that a high sMICA level was significantly related with poor prognosis among HCC patients. Multivariate analyses indicated that sMICA was an independent prognostic factor. In addition, the levels of CD56+NKG2D+NK cells were within the range of 11.2%-55.4%, and correlation analyses indicated that sMICA level was negatively correlated with the level of NKG2D+NK cells. Our results suggest that serum sMICA levels may be an independent prognostic factor for advanced HCC.

关键词：细胞水平可溶性预后血清肝癌晚期患者价值

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A novel dimeric procyanidin glucoside from Polygonum aviculare

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Chinese Chemical Letters 2012年第7期23卷 820-822页

作者： Hai jian cong Shu Wei Zhang Chong Zhang Yu Jie Huang Li jiang Xuan State Key Laboratory of Drug Research Shanghai Institute of Materia MedicaShanghai Institute for Biological SciencesChinese Academy of SciencesShanghai 201203China

A novel dimeric procyanidin glucoside,catechin 3-O-acetate-（4 α→8）-catechin 3-O-acetate-3＇-O- β-D-glucopyranoside（1）, along with five flavonoids and one lignan were isolated from the aerial parts of Polygonum ... 详细信息

关键词： Polygonum aviculare Polygonaceae Procyanidin glucoside Catechin

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Extended damage range of(Al0.3Cr0.2Fe0.2Ni0.3)3O4 high entropy oxide films induced by surface irradiation

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Chinese Physics B 2020年第6期29卷 374-378页

作者： jian-cong Zhang Sen Sun Zhao-Ming Yang Nan Qiu Yuan Wang Key Laboratory of Radiation Physics and Technology Ministry of EducationInstitute of Nuclear Science and TechnologyCollege of PhysicsSichuan UniversityChengdu 610064China

Irradiation makes structural materials of nuclear reactors degraded and ***,the damage process of materials induced by irradiation is not fully elucidated,mostly because the charged particles only bombarded the surface of the materials(within a few microns).In this work,we investigated the effects of surface irradiation on the indirect irradiation region of the(Al0.3Cr0.2Fe0.2Ni0.3)3O4 high entropy oxide(HEO)films in detail by plasma surface *** results show that the damage induced by surface irradiation significantly extends to the indirect irradiation region of HEO film where the helium bubbles,dislocations,phase transformation,and the nickel oxide segregation were observed.

关键词： high entropy oxide films surface irradiation radiation-induced segregation vacancies extended irradiation damage region

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Proteomic profiling of early degenerative retina of RCS rats

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International Journal of Ophthalmology(English edition) 2017年第6期10卷 878-889页

作者： Zhi-Hong Zhu Yan Fu Chuan-Huang Weng cong-jian Zhao Zheng-Qin Yin Southwest Hospital/Southwest Eye Hospital Third Military Medical University Chongqing 400038 China Key Lab of Visual Damage and Regeneration ＆ Restoration of Chongqing Chongqing 400038 China

AIM： To identify the underlying cellular and molecular changes in retinitis pigmentosa （RP）. METHODS： Label-free quantification-based proteomics analysis, with its advantages of being more economic and consisting of simpler procedures, has been used with increasing frequency in modern biological research. Dystrophic RCS rats, the first laboratory animal model for the study of RP, possess a similar pathological course as human beings with the diseases. Thus, we employed a comparative proteomics analysis approach for in-depth proteome profiling of retinas from dystrophic RCS rats and non-dystrophic congenic controls through Linear Trap Quadrupole - orbitrap MS/MS, to identify the significant differentially expressed proteins （DEPs）. Bioinformatics analyses, including Gene ontology （GO） and Kyoto Encyclopedia of Genes and Genomes （KEGG） pathway annotation and upstream regulatory analysis, were then performed on these retina proteins. Finally, a Western blotting experiment was carried out to verify the difference in the abundance of transcript factor E2F1. RESULTS： In this study, we identified a total of 2375 protein groups from the retinal protein samples of RCS rats and non-dystrophic congenic controls. Four hundred thirty-four significantly DEPs were selected by Student＇s t-test. Based on the results of the bioinformatics analysis, we identified mitochondrial dysfunction and transcription factor E2F1 as the key initiation factors in early retinal degenerative process. CONCLUSION： We showed that the mitochondrial dysfunction and the transcription factor E2F1 substantially contribute to the disease etiology of RP. The results provide a new potential therapeutic approach for this retinal degenerative disease.

关键词： retinal degeneration proteomics mitochondrion E2F1 MaxQuant RCS rat

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Decreased expression of Neurensin-2 correlates with poor prognosis in hepatocellular carcinoma

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World Journal of Gastroenterology 2009年第38期15卷 4844-4848页

作者： Hai-Qing Ma Xiao-Ting Liang Jing-Jing Zhao Hui Wang jian-cong Sun Yi-Bing Chen Ke Pan jian-Chuan Xia Key Laboratory of Oncology in Southern China and Departmentof Experimental Research Sun Yat-sen University Cancer CenterGuangzhou 510060 Guangdong Province China

AIM： To investigate the expression of Neurensin-2 （NRSN2） in hepatocellular carcinoma （HCC） and its prognostic values in predicting survival. METHODS： The expression and prognostic significance of NRSN2 in HCC was examined by performing immunohistochemical analysis using a total of 110 HCC clinical tissue samples, and Western blotting analysis to further confirm the result. RESULTS： Decreased NRSN2 expression was shown in 70.9% cases. Loss of NRSN2 expression in HCC was significantly related to tumor size （P = 0.006）. Larger tumor size was related to negative expression of NRSN2. Patients showing negative NRSN2 expression had a significantly shorter overall survival than those with positive expression （P = 0.008）. Multivariate Cox regression analysis indicated that NRSN2 expression level was an independent factor of survival （P = 0.013）. Western blotting analysis further confirmed decreased expression of NRSN2 in tumor tissues compared with non-tumorous tissues. CONCLUSION： Our study indicated that NRSIV2 could be a tumor suppressor gene for HCC and a candidate biomarker for long-term survival in HCC.

关键词： Neurensin-2 Hepatocellular carcinoma Expression Immunohistochemical analysis Prognosis

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