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Coupled hydro-mechanical analysis of expansive soils:Parametric identification and calibration

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Journal of Rock Mechanics and Geotechnical Engineering 2020年第3期12卷 620-629页

作者： Abhishek Rawat Linzhi Lang Wiebke Baille Anne-Catherine Dieudonne frederic collin Department of Foundation Engineering Soil and Rock MechanicsRuhr-Universität BochumUniversitätsstraße 15044780BochumGermany Faculty of Civil Engineering and Geosciences Delft University of TechnologyBuilding 232628 CN Delftthe Netherlands ArGEnCo University of Liege4000 LiegeBelgium

A methodology for identifying and calibrating the material parameters for a coupled hydro-mechanical problem is presented in this pape *** validation purpose,a laboratory-based water infiltration test was numerically simulated using finite element method(FEM).The test was conducted using a self-designed column-type experimental device,which mimicked the wetting process of a candidate backfill material in a nuclear waste *** real-time measurements of key state variables(*** content,relative humidity,temperature,and total stresses)were performed with the monitoring sensors along the height of cylindrical soil *** numerical simulation,the modified Barcelona Basic Model(BBM)along with soil-water retention model for compacted bentonite was *** shows that the identified model parameters successfully captured the moisture migration process under an applied hydraulic gradient in a bentonite-based compacted soil sample.A comparison between the measured and predicted values of total stresses both in axial and lateral directions along with other state variables revealed that heterogeneous moisture content was distributed along the hydration-path,resulting in non-uniform stress-deformation characteristics of soil.

关键词： Compacted bentonite Backfill material Deep geological repository Constitutive modeling Hydro-mechanical coupling Water infiltration test

A Non-parametric Gradient-Based Shape Optimization Approach for Solving Inverse Problems in Directed Self-Assemblyof Block Copolymers

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Communications on Applied Mathematics and Computation 2024年第2期6卷 1472-1489页

作者： Daniil Bochkov frederic Gibou Department of Mechanical Engineering University of CaliforniaSanta BarbaraSanta BarbaraCA93106USA Department of Computer Science University of CaliforniaSanta BarbaraSanta BarbaraCA 93106 USA

We consider the inverse problem of finding guiding pattern shapes that result in desired self-assembly morphologies of block copolymer ***,we model polymer selfassembly using the self-consistent field theory and derive,in a non-parametric setting,the sensitivity of the dissimilarity between the desired and the actual morphologies to arbitrary perturbations in the guiding pattern *** sensitivity is then used for the optimization of the confining pattern shapes such that the dissimilarity between the desired and the actual morphologies is *** efficiency and robustness of the proposed gradient-based algorithm are demonstrated in a number of examples related to templating vertical interconnect accesses(VIA).

关键词： Block copolymers Directed self-assembly Inverse design Shape optimization Vertical interconnect accesses(VIA)

Growth of RB Population in the Conversion Phase of Chlamydia Life Cycle

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Communications on Applied Mathematics and Computation 2024年第1期6卷 90-112页

作者： frederic Y.M.Wan Department of Mathematics University of CaliforniaIrvineCA92697-3875USA

Upon infecting a host cell,the reticulate body(RB)form of the Chlamydia bacteria simply proliferates by binary fission for an extended *** data show only RB units in the infected cells 20 hours post infection(hpi),spanning nearly half way through the development *** data collected every 4 hpi,conversion to the elementary body(EB)form begins abruptly at a rapid rate sometime around 24 *** modeling proliferation and conversion as simple birth and death processes,it has been shown that the optimal strategy for maximizing the total(mean)EB population at host cell lysis time is a bang-bang control qualitatively replicating the observed conversion ***,the simple birth and death model for the RB proliferation and conversion to EB deviates in a significant way from the available data on the evolution of the RB population after the onset of RB-to-EB *** working with a more refined model that takes into account a small size threshold eligibility requirement for conversion noted in the available data,we succeed in removing the deficiency of the previous models on the evolution of the RB population without affecting the optimal bang-bang conversion strategy.

关键词： Chlamydia Life cycle Optimal control Maximal infectious spread Specie competitive survival

Education of Hospitalized Diabetic Patients: Analysis of Training Needs among Nurses in a Lebanese Hospital - A Secondary Publication

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Journal of Clinical and Nursing Research 2024年第4期8卷 353-369页

作者： Nisrine Moubarak frederic Douville Laval University Quebec CityQuebecCanada

The design of diabetes inpatient educational preparation should be based on the needs of the nurses involved in terms of skills in this area. The objective of this qualitative study is to identify the preparatory needs of nurses working in the medical and surgical units of a Lebanese hospital in terms of Survival Skills Education for Hospitalized Diabetic Patients (SSEHDP). Method: The focus group method is used for data collection using a semi-structured interview guide. The needs expressed by the thirty-two participating nurses were classified into categories of the competency framework for providing self-management education to diabetic patients proposed by the American Diabetes Association. Results: By focusing on the themes of an SSEHDP, a list of preparatory needs was drawn up. The needs identified and analyzed are then translated into general and specific learning objectives for educational preparation. Conclusion: The needs analysis is only the first step in a work that will ideally continue into the implementation and eventual evaluation of an educational program developed to help nurses acquire skills in the education of diabetic patients.

关键词： Diabetes inpatient education Nurse training needs Survival Skills Education for Hospitalized Diabetic Patients(SSEHDP) Qualitative study Competency framework

Simultaneous genetic transformation and genome editing of mixed lines in soybean(Glycine max)and maize(Zea mays)

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aBIOTECH 2024年第2期5卷 169-183页

作者： Michelle Valentine David Butruille frederic Achard Steven Beach Brent Brower-Toland Edward Cargill Megan Hassebrock Jennifer Rinehart Thomas Ream Yurong Chen Bayer Crop Science 700 Chesterfield Parkway WChesterfieldMO 63017USA

Robust genome editing technologies are becoming part of the crop breeding ***,genome editing is usually conducted either at a single locus,or multiple loci,in a variety at one *** parallel genomics platforms,multifaceted genome editing capabilities,and flexible transformation systems enable targeted variation at nearly any locus,across the spectrum of genotypes within a *** demonstrate here the simultaneous transformation and editing of many genotypes,by targeting mixed seed embryo explants with genome editing machinery,followed by re-identification through genotyping after plant *** and Editing of Mixed Lines(TREDMIL)produced transformed individuals representing 101 of 104(97%)mixed elite genotypes in soybean;and 22 of 40(55%)and 9 of 36(25%)mixed maize female and male elite inbred genotypes,*** of edited genotypes for the regenerated individuals identified over 800 distinct edits at the Determinate1(Dt1)locus in samples from 101 soybean genotypes and 95 distinct Brown midrib3(Bm3)edits in samples from 17 maize *** results illustrate how TREDMIL can help accelerate the development and deployment of customized crop varieties for future precision breeding.

关键词： Maize Soybean Seed embryo explants TREDMIL Genetic transformation Genome editing

Cost-Effective Monitoring of the Fuel Air Equivalence-Ratio with a Lambda Sensor and a Microcontroller in a Downdraft Biomass Gasifier

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Open Journal of Applied Sciences 2024年第2期14卷 545-560页

作者： Jean Fidele Nzihou Salou Hamidou Ousmane Zoundi frederic Ouattara Bila Gerard Segda Formation and Research Unit in Sciences and Technologies University Norbert ZONGO Koudougou Burkina-Faso

The operation of biomass treatment devices such as gasifiers is based on the control of key parameters that play an important role in product formation. These include: temperature, excess oxygen, relative humidity and biomass composition. This work focuses on excess oxygen and temperature. Unfortunately, flue gas oxygen analyzers are expensive and not accessible to small industries. However, the equivalence ratio is linked to excess oxygen and has the advantage of not depending on biomass composition. This study therefore focuses on the design and development of a device for controlling this equivalence ratio by measuring oxygen concentration using a self-propelled Lambda probe, and a system for monitoring this equivalence ratio using an Arduino Uno 3 microcontroller. The temperature is recorded with an accuracy of ±1.5°C. For a heating time of 10 minutes, the response time to temperature change is around 3 seconds, which is sufficient for the device to function properly. This simple device is an efficient and cost-effective means of checking the equivalence ratio.

关键词： Equivalence Ratio Biomass Gasification Lambda Sensor Microcontroller C++

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绿色金融为中国经济的可持续发展注入动力

新金融 2024年第1期 10-14页

作者：范力民汇丰银行

目前,中国经济的发展面临着一系列挑战,需要妥善处理经济结构转型的问题,其中向绿色转型发展的需求日益迫切,因此建立合适的转型机制,为中国经济的绿色转型与可持续发展注入动力是当前中国经济的重要任务。本文梳理了中国近年来绿色转... 详细信息

目前,中国经济的发展面临着一系列挑战,需要妥善处理经济结构转型的问题,其中向绿色转型发展的需求日益迫切,因此建立合适的转型机制,为中国经济的绿色转型与可持续发展注入动力是当前中国经济的重要任务。本文梳理了中国近年来绿色转型方面的进展,从绿色贷款、绿色债券和绿色股权投资等方面分析了中国为建立多层次绿色金融体系而做出的努力,指出绿色转型需要更多社会资本参与,并根据《G20转型金融框架》中的“五个支柱”进一步明确提出了中国经济绿色转型分类、实施碳税以激励转型、提高气候信息披露要求、通过VC/PE/PPP等融资方式拓宽民间投资渠道、增加针对性货币和财政工具等建议,以期为中国的绿色转型发展提供参考。

关键词：绿色金融绿色转型可持续发展社会资本

A novel homozygous missense variant in ARSK causes MPS X,a new subtype of mucopolysaccharidosis

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Genes & Diseases 2024年第3期11卷 87-90页

作者： Miao Sun Cornelia K.Kaminsky Philip Deppe Mai-Brittllse frederic M.Vaz Barbara Plecko Torben Lubke Linda M.Randolph Division of Genomic Medicine Department of Pathology and Laboratory MedicineChildren's Hospital Los Angeles/Keck School of Medicine of USCLos AngelesCA 90027USA Department of Radiology Children's Hospital Los Angeles/Keck School of Medicine of USCLos AngelesCA 90027USA Department of Chemistry BiochemistryBielefeld UniversityBielefeld 33615Germany Amsterdam UMC Location University of Amsterdam Department of Clinical Chemistry and PediatricsLaboratory Genetic Metabolic DiseasesEmma Children's HospitalMeibergdreef 9Amsterdam 1100 DEthe Netherlands Amsterdam Gastroenterology Endocrinology Metabolism Inborn Errors of MetabolismAmsterdam 1105 BKthe Netherlands Core Facility Metabolomics Amsterdam UMC Location University of AmsterdamAmsterdam 1100DDthe Netherlands Department of Pediatrics Division of General PediatricsMedical Universityof GrazGraz8036Austria Division of Medical Genetics Department of PediatricsChildren's Hospital Los Angeles/Keck School of Medicine of USCLos AngelesCA 90027USA

Mucopolysaccharidoses(MPS)are a group of rare inborn errors of metabolism caused by defective lysosomal enzymes which prevent cells from degrading and recycling certain carbohydrates and fats,resulting in the storage of glycosaminoglycans in cells throughout the *** leads to multisystem abnormalities involving bone,connective tissues,brain,blood,spinal cord,skin,and other tissues.

关键词： metabolism doses polys

Automatic Detection and Characterization of Human Veins Using Infra-Red Image Processing

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Journal of Computer and Communications 2024年第9期12卷 141-159页

作者： Jean Ndoumbe Brice Ekobo Akoa Gaelle Patricia Talotsing frederic Franck Kounga Samuel Kaissassou Bertin Chouanmo Njo Laboratory of Computer Engineering Data Science and Artificial Intelligence Department of Computer & Telecommunications Engineering National Higher Polytechnic School Douala Cameroon Laboratory of Electrical Engineering Mechatronics and Signal Processing Department of Electrical & Telecommunications Engineering National Advanced School of Engineering Yaound Cameroon Mobile Computing and Networking Research Laboratory Department of Computer and Software Engineering Polytechnique Montreal Montreal Canada DigiPlus SARL Bonamoussadi Douala Cameroon

The detection and characterization of human veins using infrared (IR) image processing have gained significant attention due to its potential applications in biometric identification, medical diagnostics, and vein-based authentication systems. This paper presents a low-cost approach for automatic detection and characterization of human veins from IR images. The proposed method uses image processing techniques including segmentation, feature extraction, and, pattern recognition algorithms. Initially, the IR images are preprocessed to enhance vein structures and reduce noise. Subsequently, a CLAHE algorithm is employed to extract vein regions based on their unique IR absorption properties. Features such as vein thickness, orientation, and branching patterns are extracted using mathematical morphology and directional filters. Finally, a classification framework is implemented to categorize veins and distinguish them from surrounding tissues or artifacts. A setup based on Raspberry Pi was used. Experimental results of IR images demonstrate the effectiveness and robustness of the proposed approach in accurately detecting and characterizing human. The developed system shows promising for integration into applications requiring reliable and secure identification based on vein patterns. Our work provides an effective and low-cost solution for nursing staff in low and middle-income countries to perform a safe and accurate venipuncture.

关键词： Vein Detection Blood Radiation Infrared Image CLAHE Algorithm Raspberry Pi