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Potential Benefits of Green Tea in Prostate Cancer Prevention and Treatment:A Comprehensive Review

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Chinese Journal of Integrative Medicine 2024年第11期30卷 1045-1055页

作者： LIU Gui-hong YAO Ze-qin chen guo-qiang LI Ya-lang LIANG Bing Department of Urology Sanya Central Hospital(The Third People's Hospital of Hainan Province)Sanya CityHainan Province 572000China Department of Urology Yuzhou People's HospitalXuchang CityHenan Province 461670China

Prostate cancer is a prevalent and debilitating disease that necessitates effective prevention and treatment *** tea,a well-known beverage derived from the Camellia sinensis plant,contains bioactive compounds with potential health benefits,including catechins and *** comprehensive review aims to explore the potential benefits of green tea in prostate cancer prevention and treatment by examining existing *** tea possesses antioxidant,anti-inflammatory,and anti-carcinogenic properties attributed to its catechins,particularly epigallocatechin *** studies have reported an inverse association between green tea consumption and prostate cancer risk,with potential protection against aggressive forms of the *** studies demonstrate that green tea components inhibit tumor growth,induce apoptosis,and modulate signaling pathways critical to prostate cancer development and *** trials and human studies further support the potential benefits of green *** tea consumption has been found to be associated with a reduction in prostate-specific antigen levels,tumor markers,and played a potential role in slowing disease ***,challenges remain,including optimal dosage determination,formulation standardization,and conducting large-scale,long-term clinical *** review suggests future research should focus on combinatorial approaches with conventional therapies and personalized medicine strategies to identify patient subgroups most likely to benefit from green tea interventions.

关键词： green tea prostate cancer prevention treatment epigallocatechin gallate review

Hypoxia-regulated apoptosis-inducing factor protects mitochondrial PTEN from oxidation to modulate epithelial-mesenchymal transition and metastasis of cancers

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中国病理生理杂志 2015年第10期 1834-1835页

作者： SHEN Shao-ming guo Meng YU Yun XIONG Zhong chen guo-qiang Department of Pathophysiology Key Laboratory of Cell Differentiation and ApoptosisChinese Ministry of EducationShanghai Jiaotong University School of Medicine

Apoptosis-inducing factor(AIF),a FAD-containing,NADH-dependent oxidoreductase residing in the mitochondria,has dualroles in cell death and survival,but its specific enzymatic activity and potential roles in the pathogenesis of cancers remain *** we report that the tumor suppressor PTEN is localized into mitochondria,and AIF physically interacts with and protects PTEN

关键词： PTEN Hypoxia-regulated apoptosis-inducing factor protects mitochondrial PTEN from oxidation to modulate epithelial-mesenchymal transition and metastasis of cancers AIF

ESTIMATE OF DISCRETE NONLINEARITIES IN A MAINLY LINEAR DYNAMIC SYSTEM

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Chinese Journal of Mechanical Engineering 2001年第3期14卷 286-288页

作者： chen Manru,guo qiang (Faculty of Design ,Northwest University of Light Industry) chen Yingru (Hebei Highway Engineering Construction Group Co. Ltd.) 西北轻工业学院设计学院陕西河北公路工程建设集团有限公司河北

The class of system considered is a single degree of freedom undamped vibrating system with a clearance in which the dynamical behavior is described by a state-space representation in real time. The direct identification technique for the estimate of a clearance and other parameters in the system is presented in terms of least squares method and step-by-step iteration approach. For numerical simulation purpose, the simulated data are achieved by corrupting the modeled responses. The mathematical algorithm, which is put forward, has proven to be effective through a practical numerical example.

关键词： Vibrating system Clearance Linear regression Numerical simulation

Carbon-free D_(3d) [E_3ME_3]^(2-) (E=P,As;M=Ni,Pd,Pt):The smallest inorganic sandwich complexes with aromatic η~3-P_3^- and η~3-As_3^- ligands

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Science China Chemistry 2010年第4期53卷 940-944页

作者： MIAO ChangQing, chen qiang, guo JinChang & LI SiDian Institute of Materials Science and Department of Chemistry, Xinzhou Teachers’ University, Xinzhou 034000, China 1. Institute of Materials Science and Department of Chemistry Xinzhou Teachers’ University Xinzhou 034000 China

A density functional theory and wave function theory investigation on the possibility of carbon-free phosphametallocenes [P3MP3]2-and arsenametallocenes [As3MAs3]2- (M=Ni, Pd, Pt) is presented in this work. Staggered singlet D3d [E3ME3]2- (E=P, As)-the smallest inorganic metallocenes possible to construct-proved to be the global minima of the heptaatomic sys- tems and may be targeted in future experiments. Cyclo-P3- and cyclo-As3- turned out to possess similar aromaticity to cyclo-P5- and cyclo-As5- and may serve as effective ligands to sandwich a wide range of transition metals. The first vertical electron detachment energies of Cs [E3ME3]Li+ monoanions with a staggered [E3ME3]2- sandwich core were predicted to be between 2.7 and 2.9 eV; the extent of stabilization by Li+ suggests that such materials be viable targets for experimental characterization.

关键词： phosphorus arsenic sandwich complexes density functional theory geometries electronic structures.

Microwave Generation from an Oscillating Virtual Cathode Produced by Non-homogeneous Electron Beams

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Chinese Physics Letters 1997年第2期14卷 117-120页

作者： LIU Jin-liang ZHANG Ya-zhou LI Chuan-lu TAN Qi-mei chen guo-qiang WANG Yong Department of Applied Physics National University of Defense TechnologyChangsha 410073

Microwave generation from a resonant cavity surrounding oscillating virtual cathode,which is produced by non-homogeneous electron beams,is studied *** microwave power is measured by using the crystal detector and frequencies are measured by using the heterodyne technique.A single microwave pulse contains two microwave signals with different frequencies,one peak power is 1.12MW at 5.03GHz and the other is 0.56MW at 5.24GHz,and their 3dB bandwidths are 18 and 25 MHz,respectively.

关键词： technique. Microwave microwave

Influence of Low-Energy Ion Irradiation on Plasma Membrane Permeability of Cells

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Chinese Physics Letters 2000年第1期17卷 61-63页

作者： ZHANG Dong-Mei CUI Fu-Zhai SUN Su-Qin LIN You-Bo TIAN Min-Bo chen guo-qiang Department of Materials Science and Engineering Tsinghua UniversityBeijing 100084 Analysis Center Tsinghua UniversityBeijing 100084 Department of Biological Science and Biotechnology Tsinghua UniversityBeijing 100084

Effect of low-energy ion irradiation on plasma membrane permeability has been investigated by using electron spin resonance(ESR)spectroscopy of spin probe *** investigated system is plumule cells of wheat(Triticum aestivum L.)seeds implanted by 30 keV N^(+) *** spectra indicated that plasmalemma permeability is sensitive to low-energy ion *** irradiations with increasing Huences up to semi-lethal dose lead to gradual increase in plasmalemma permeability of the plumule *** possible factors relevant to the changes in membrane permeability are discussed in relation to the changes in the physical state and chemical nature of membranes.

关键词： technique. permeability irradiation

Moleucle action mechunisms of NM-3 on human gastric cancer SGC-7901 Cells in vivo or in vitro

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World Journal of Gastroenterology 2003年第10期9卷 2366-2369页

作者： Jin-Shui Zhu Bo Shen Jin-Lian chen guo-qiang chen Xiao-Hu Yu Hua-Fang Yu Zu-Ming Zhu, Affiliated Sixth People’s Hospital, Shanghai Jiaotong University, Shanghai 200233, China guo-qiang chen, Shanghai Experimental Animal Center, Chinese Academy of Sciences, Shanghai 200233, China Shanghai Jiao Tong Univ Affiliated Peoples Hosp 6 Dept Gastroenterol Shanghai 200233 Peoples R China Chinese Acad Sci Shanghai Expt Anim Ctr Shanghai 200233 Peoples R China

AIM: To study the moleucle action mechunisms of NM-3 on the growth of human gastric cancer SGC-7901 cells in vivo or in ***: SGC-7901 from human non-differentiated gastric cancer cell line was cultured with NM-3 at 100 mg/ml for 24 h. We observed its inhibitory rate and the density of micro-vascular growth in grafted mice with human gastric cancer SGC-7901. The apoptosis of human gastric cancer SGC-7901 was revealed in NM-3 treatment group by using terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate-fluorescene nick end labeling (TUNEL)method and flow cytometry ***: The growth of SGC-7901 cells was markedly inhibited compared with control growp, which was smaller than that in normal saline control group (4.17 g±0.22 g VS 9.45 g±1.38 g, P＜0.01). The level of apoptosis of human gastric cell line SGC-7901 was obviously increased in NM-3treatment group at 1 mg.L-1 for 24 h. NM-3 inducing apoptotic index in NM-3 plus carboplatin group was 3.5 times that of carboplatin control group (TUNEL: 27.98±6.12 % VS 12.94±2.12 %, FACScan: 26.86±5.69 % VS11.86±1.09 %,P＜0.01). Western blot analysis showed that the apoptotic index of human gastric cancer was elevated for 12, 24 and 36 h with an evident time-effect relationship in groups at 100 mg.L-L. NM-3 enhanced the inhibitive effects and sensitivity of chemotherapy for human gastric cancer in nude mice. These results suggested that NM-3 played a key inhibitive role in the growth of grafted human gastric cancer in nude ***: NM-3 can inhibit the growth of human gastric cancer cell line SGC-7901, and enhance the sensitivity of carboplatin on SGC-7901 and induced its apoptosis.

关键词：胃癌分子机制 SGC-7901细胞微血管形成 TUNEL法细胞凋亡 NM-3

Peroxiredoxin Ⅰ is a target of adenanthin for leukemic cell differentiation

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Peroxiredoxin Ⅰ is a target of adenanthin for leukemic cell...

华东六省一市生物化学与分子生物学学会-2011年学术交流会

作者： chen guo-qiang Shanghai Universities E-Institute for Chemical Biology Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of EducationShanghai Jiao Tong University School of Medicine(SJTU-SM)

Several diterpenoids,which form a large class of secondary metabolites isolated from plants 1,are believed as a promising source of new prototypes for the discovery and development of novel therapeutic agents against cancers,cardiovascular diseases,inflammatory and ***,their activities and target molecule(s)remain to be *** we show that adenanthin,a diterpenoid isolated from the leaves of Rabdosia

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位场数据解释的Theta-Depth法

地球物理学报 2016年第6期59卷 2225-2231页

作者：陈国强马国庆吉林大学地球科学学院长春130061 吉林大学地球探测科学与技术学院长春130021

Theta图是利用位场(重磁)数据识别边界的常用方法,其表达式为重磁异常水平变化与垂直变化的比值函数.该方法计算浅源地质体边界的效果较好,而由于深源位场数据在换算过程中会产生趋同效应,在深源地质体识别应用中计算结果不准确,为此,... 详细信息

Theta图是利用位场(重磁)数据识别边界的常用方法,其表达式为重磁异常水平变化与垂直变化的比值函数.该方法计算浅源地质体边界的效果较好,而由于深源位场数据在换算过程中会产生趋同效应,在深源地质体识别应用中计算结果不准确,为此,本文提出Theta-Depth法并进行地质体埋深的计算.首先给出直接利用Theta图像进行场源体深度估算的方法,然后推导出基于Theta导数的线性方程来自动估算场源位置参数,本文方法可有效地利用Theta图像的特征为约束条件来提高反演结果的精度.理论模型试验证明本文提出的Theta-Depth法能有效地计算出场源体位置和深度.将该方法应用于满都拉地区实测磁数据的解释,帮助圈定了矿脉的分布.

关键词： Theta 位场深度线性方程