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Renal function of donors and recipients after living donor kidney transplantation in a Chinese cohort

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Chinese Medical Journal 2011年第9期124卷 1290-1295页

作者： GONG Nian-qiao MING Chang-sheng ZENG Fan-jun ZHANG Wei-jie LIN Zhen-bin ZHOU ping chen xiao-ping chen Zhi-shui Institute of Organ Transplantation Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei 430030 China Department of Surgery Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei 430030 China

Background Living donor kidney transplantation （LKT） has been booming in China. This study aimed to elucidate the renal function of both Chinese donors and recipients after the donation and transplantation. Methods One hundred and forty-one pairs of donors and recipients for LKT were randomly selected and followed up for up to seven years. The donors＇ and recipients＇ renal function was recorded before and after operation. Results The donors presented a mean age of （43.9±7.5） years at donation. The female contributed 101/141 （71.6%） in all donors, and no effect was shown between genders on healthy donors＇ renal function. The donors＇ glomerular filtration rates （GFR） were （119.5±20.4） ml/min, （85.2±17.6） ml/min, （87.2±15.9） ml/min, （82.1±14.6） ml/min and （83.0±13.7） ml/min preoperatively, and for five days, three months, one year and beyond one year after the operation. The donors for the period of 1-3 years, 3-5 years and more than 5 years after donation showed GFR as （83.9±12.7） ml/min, （83.0±17.6） ml/min, and （80.9±20.8） ml/min, respectively, no statistically significant difference was found. Moreover, no significant clinical changes in blood pressure and proteinuria were found among the donors. In the recipients, delayed graft function （DGF） rate was 6.4%, acute rejection rate was 11.3%, and GFR were （66.5±16.4） ml/min, （73.2±19.6） ml/min and （63.9±18.6） ml/min respectively at three months, one year and beyond one year post-transplantation respectively. Conclusion The donors/recipients of LKT in Chinese population experience well-functioning remaining/donor kidneys.

关键词： kidney transplantation living donors recipient renal function

Isotopic characteristics and source analysis of atmospheric ammonia during agricultural periods in the Xichuan area of the Danjiangkou Reservoir

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Journal of Environmental Sciences 2024年第2期136卷 460-469页

作者： xiaoshu chen Tongqian Zhao Chunyan xiao xiaoming Guo Feihong chen Institute of Resources and Environment Henan Polytechnic UniversityJiaozuo 454000China

Nitrogen deposition is an important means of exogenous nitrogen input in reservoir *** activities around the reservoir lead to a sharp increase in the concentration of ammonia in the atmosphere,which poses a threat to the reservoir water *** the contribution of agricultural ammonia release to atmospheric NH_(x)(gaseous NH_(3)and particulate NH_(4)^(+)),in the reservoir area can provide a theoretical foundation for local reactive nitrogen *** collected atmospheric NH_(3)and NH_(4)^(+)samples during the agricultural periods and analyzed the isotopic characteristics of atmospheric NH_(x)and the contribution rates of different ammonia sources in the Xichuan area of the Danjiangkou *** results showed that the initialδ~(15)N values of NH_(3)(-30.0‰to–7.2‰)and particulate NH_(4)^(+)(–33‰to+4.9‰for finer and coarser particles,respectively)are different,and their contribution ratios from dissimilar ammonia sources are also different,among which NH_(4)^(+)is more susceptible to meteorological ***,since the atmospheric NH_(x)in the Xichuan area is mainly gaseous NH_(3),the final sources of atmospheric ammonia nitrogen source depend on gaseous NH_(3).Agricultural sources(59%-74%)were the main NH_(3)sources in this *** them,the fertilizer use emission was dominant;it had the highest contribution rate in summer during the agricultural period and a more prominent impact in areas with less human *** regulation of the application of high-ammonia releasing fertilizer,especially during the agricultural period in summer,is an effective way to reduce the threat of atmospheric ammonia to water health.

关键词： Danjiangkou reservoir Atmospheric ammonia nitrogen Isotope Ammonia source analysis Agricultural sources

Preoperative serum lipid profile and outcome in nonmetastatic colorectal cancer

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Chronic Diseases and Translational Medicine 2016年第4期2卷 -页

作者： Ting-Ting Hong Di Shen xiao-ping chen xiao-Hong Wu Dong Hua Department of Medical 0ncology Affiliated Hospital of Jiangnan University and Wuxi 4th People's Hospital Wuxi Jiangsu 214062 China

Objective: A large portion of non-metastatic colorectal cancers (non-mCRCs) recur after curative surgery. In addition to the traditional tumor-related factors, host-related factors are also required to accurately predict prognosis. A few studies have shown an association between the serum lipid profile and the survival and treatment response of patients with colorectal cancer. Methods: We retrospectively evaluated the prognostic significance of the preoperative serum lipid profile [total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C)] in patients with non-mCRC treated with curative surgery. The Spearman rank correlation test was used to analyze associations between lipid levels and categorical variables. Lipid levels were modeled as four equal-sized quartiles based on the distribution among the whole cohort. Kaplan-Meier curves were used to estimate survival probabilities, and the log-rank test was used to detect differences between them. Multivariate fractional polynomial (MFP) analysis was used to model any non-linear effects and avoid categorization. To evaluate the added prognostic value of lipids, the predictive power of two models (with and without lipids as covariates) was compared by using Harrell's C-statistic and the Akaike information criterion (AIC). Results: A total of 266 patients with non-mCRC were enrolled in the present study. Spearman rank correlation test showed that TG levels inversely correlated with N stage (r ? ?0.20, P ? 0.00) and Tumor-Node-Metastasis (TNM) stage (r ? ?0.19, P ? 0.00). HDL-C levels positively correlated with perineural invasion (PNI) (r ? 0.15, P ? 0.02), and LDL-C levels inversely correlated with lymphovascular invasion (LVI) (r ? ?0.12, P ? 0.04). None of the four lipids predicted overall survival (OS) in univariate or multivariate analyses adjusted for age, gender, T stage, N stage, TNM stage, histological grade, tumor deposits,

关键词： Serum lipids Colorectal cancer Overall survival Prognostic model

Acute changes of blood pressure and heart rate induced by a strong earthquake

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Chinese Medical Journal 2010年第8期123卷 1084-1085页

作者： HE Sen chen xiao-ping LI Jiang-bo LIN Jian-lan LUO Xue-ju LUO xiao-jia Department of Cardiology West China Hospital Sichuan University Chengdu Sichuan 610041 China

Ahigh death toll during an earthquake comes not only from injuries related to the destruction of buildings or road accidents but also from sudden death resulting from cardiovascular problems, as clearly shown in reports. The increased rate of cardiovascular mortality during an earthquake has been ascribed to the impact of a major emotional stress on the heart, mediated through an increase in cardiac sympathetic activity, and probably including some other neuroendocrine mechanisms. A rise in blood pressure （BP） and heart rate （HR） may be directly responsible for the increased rate of cardiovascular mortality during an earthquake. Previously published studies about the acute changes of BP and HR used indirect information,

关键词： ambulatory blood pressure acute changes earthquake stress

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面向智能服务机器人任务规划的行动语言扩展

软件学报 2013年第7期24卷 1614-1625页

作者：靳国强陈小平中国科学技术大学计算机科学与技术学院安徽合肥230027

针对智能服务机器人的任务规划,引入复合行动对行动语言C+进行了扩展,并实现了其求解系统.在扩展的行动语言C+中,复合行动被定义成一定条件下一系列基本行动的连续执行.通过刻画扩展的行动描述和其对应的转移系统的关系,证明了扩展行动... 详细信息

针对智能服务机器人的任务规划,引入复合行动对行动语言C+进行了扩展,并实现了其求解系统.在扩展的行动语言C+中,复合行动被定义成一定条件下一系列基本行动的连续执行.通过刻画扩展的行动描述和其对应的转移系统的关系,证明了扩展行动语言相对于原始行动语言的可靠性和完备性.在智能服务机器人的任务规划中,复合行动可以看成是一种对于机器人能力的"高层"抽象.这样的扩展使得对于机器人规划系统的建模更加直观,具有更大的灵活性,并且扩展有增量式的优点.实验结果表明,通过引入复合行动,对于比较复杂的机器人任务规划问题,可以很好地改进求解效率.

关键词：非单调推理自动规划服务机器人

Molecular Characteristics of Cephalosporin-Resistant Neisseria gonorrhoeae Strains in China:A Retrospective Study

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International Journal of Dermatology and Venereology 2024年第2期7卷 78-83页

作者： Jin Zhang xiao-Yu Zhu Jing-Wei Liu Yue-ping Yin Shao-Chun chen Reference Laboratory for STD Control Hospital for Skin Diseases(Institute of Dermatology)Chinese Academy of Medical Sciences&Peking Union Medical CollegeNanjingJiangsu 210042China National Center for STD Control Chinese Center for Disease Control and PreventionNanjingJiangsu 210042China

Objective:An increasing level of antimicrobial resistance to extended-spectrum cephalosporins has been reported,so we conducted this study to investigate the molecular characteristics of cephalosporin resistant Neisseria gonorrhoeae(NG)strains isolated from China Gonococcal Antimicrobial Resistance Surveillance Programme(China-GRSP).Methods:In total,2,038 NG isolates were collected from the China-GRSP between 2015 and *** multiantigen sequence typing(NG-MAST),multilocus sequence typing(MLST),and NG sequence typing for antimicrobial resistance(NG-STAR)were used to determine characteristics and resistant determinants of cephalosporin-resistant *** results are described as ***:Seventy-four(3.6%)cephalosporin-resistant isolates were ***_(ST7363)was the most prevalent MLST among cefixime-resistant(CFX-R)isolates,whereas MLST_(ST7365)(n=8)in was the most prevalent sequence type among ceftriaxone-resistant(CRO-R)***-R strains were mainly associated with penA-X(n=27,44.3%),penA-XIII(n=6,9.8%),penA-XVIII(n=5,8.2%),and CRO-R strains were mainly related to penA-XVIII(n=10,25.6%),penA-43(n=9,23.1%),penA-XIII(n=7,17.9%).Conclusion:The main conclusion of this study is that the predominant cephalosporin-resistant clones in China include locally emerged and imported *** CFX-R and CRO-R strains are primarily related to penA mutations,and their predominant genotypes are *** the increase in international travel,tracking high-risk-resistant clones and identifying outbreaks and their associations with epidemiological characteristics are critical to improve public health.

关键词： gonorrhea resistance cephalosporin cefixime ceftriaxone

一种描述逻辑与逻辑程序相结合的杂合系统DLclog

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软件学报 2008年第12期19卷 3100-3110页

作者：杨方凯陈小平中国科学技术大学计算机科学与技术系多主体系统实验室安徽合肥230027

面向语义Web的需求,提出了一种新的描述逻辑与逻辑程序结合的杂合系统DLclog,它从语法和语义两方面扩展了Rosati提出的DL+log系统.在DLclog中,负DL原子可以出现在逻辑程序规则体中,并且使用McCarthy的并行限制(parallel circumscription... 详细信息

面向语义Web的需求,提出了一种新的描述逻辑与逻辑程序结合的杂合系统DLclog,它从语法和语义两方面扩展了Rosati提出的DL+log系统.在DLclog中,负DL原子可以出现在逻辑程序规则体中,并且使用McCarthy的并行限制(parallel circumscription)对其进行非经典解释,即出现在规则体中的DL谓词在其他DL谓词的解释任意发生变化的情况下,其外延在DL本体的模型中被解释为最小.使用这种方法,DL+log的非单调语义(NM-semantics,简称NM语义)被扩展成了DLclog的非单调限制语义(nonmonotonic circumscriptive semantics,简称NMC语义),从而成为目前表达能力和推理能力最强的杂合系统.此外,在DL本体使用ALCIO和ALCQO书写,且不允许属性(role)出现在规则中的失败否定(NAF)之后时,还给出了可靠完全的推理算法和NMC语义下可满足性的判定复杂度.

关键词：限制描述逻辑杂合系统逻辑程序规则语义Web

Single-Ni-atoms on nitrogenated humic acid based porous carbon for CO_(2) electroreduction

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Frontiers of Chemical Science and Engineering 2024年第5期18卷 37-47页

作者： Delei Yu Ying chen Yao chen Xiangchun Liu Xianwen Wei ping Cui Anhui Key Laboratory of Coal Clean Conversion&Utilization School of Chemistry and Chemical EngineeringAnhui University of TechnologyMa’anshan 243002Chin

tWe proposed a facile synthesis of single-Ni-atom catalysts on low-cost porous carbon using a calcina-tion method at the temperatures of 850-1000°C,which were used for CO_(2) electrochemical reduction to *** porous carbon was prepared by carbonizing cheap and abundant humic *** structural characterizations of the as-synthesized catalysts and their electrocatalytic performances were *** results showed that the single-Ni-atom catalyst activated at 950°C showed an optimum catalytic performance,and it reached a CO Faradaic efficiency of 91.9% with a CO partial current density of 6.9 mAcm^(-2)at-0.9 V *** hydrogen electrode(RHE).Additionally,the CO Faradaic efficiency and current density of the optimum catalyst changed slightly after 8 h of continuous operation,suggesting that it possessed an excellent *** structure-activity relations indicate that the variation in the CO_(2) electroche-mical reduction performance for the as-synthesized catalysts is ascribed to the combined effects of the increase in the content of pyrrolic N,the evaporation of Ni and N,the decrease in pore volume,and the change in graphitization degree.

关键词： CO_(2) electroreduction single-Ni-atom cataly-sts humic acid based porous carbon

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群桩效应有限元分析

岩土力学 2005年第2期26卷 299-302页

作者：汤斌陈晓平武汉大学土木建筑工程学院

利用有限元方法,对竖向荷载作用下复合桩基的群桩效应进行了计算分析,讨论了桩长 L、桩距与桩径之比 Sa/d、桩数 n、土类等对群桩效应及群桩效应系数η的影响。结果表明:复合桩基中各个基桩的极限承载力 Qu及η随 L 增大而增大;当 Sa/d... 详细信息

利用有限元方法,对竖向荷载作用下复合桩基的群桩效应进行了计算分析,讨论了桩长 L、桩距与桩径之比 Sa/d、桩数 n、土类等对群桩效应及群桩效应系数η的影响。结果表明:复合桩基中各个基桩的极限承载力 Qu及η随 L 增大而增大;当 Sa/d 小于某个数值时,Qu,η随 Sa/d 增大而增大;当 Sa/d 大于某个数值时,Qu,η随 Sa/d 增大而减小。群桩效应及η与土类有关;η存在极大值,随 n 增多而减小,但减幅不大。

关键词：复合桩基群桩效应群桩效应系数有限元分析