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Structure and electrochemical properties of La, F dual-doped liLa_(0.01)Mn_(1.99)O_(3.99)F_(0.01) cathode materials

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Journal of University of Science and Technology Beijing 2008年第4期15卷 468-473页

作者： meng chen Shengjun li Chuang Yang College of Material Science and Chemical Engineering Harbin Engineering University Harbin 150001 China

The cathode materials liMn2O4 and rare earth elements La-doped or La and F dual-doped spinel lithium manganese *** synthesized by the citric acid-assisted sol-gel method. The synthesized samples were investigated by differential thermal analysis （DTA） and thermogravimetry （TG） measurements, X-ray diffraction （XRD）, scanning electronic microscope （SEM）, cyclic voltammetry （CV）, and charge-discharge test. XRD data shows that all the samples exhibit the same pure spinel phase, and the liLa0.01Mn1.99O3.99F0.01 and ***.9904 samples have smaller lattice parameters and unit cell volume than liMn2O4. SEM indicates that liLa0.01Mn1.99O3.99F0.01 has a slightly smaller particle size and a more regular morphology structure with narrow size distribution. The charge-discharge test reveals that the initial capacities of liMn2O4, liLa0.01Mn1.99O4, and liLa0.01Mn1.99O3.99F0.01 are 129.9, 122.8, and 126.4 mAh·g^-1, and the capacity losses of the initial values after 50 cycles are 14.5%, 7.6%, and 8.0%, respectively The CVs show that the La and F dual-doped spinel displays a better reversibility than liMn2O4.

关键词： lithium ion battery cathode material liMn2O4 structure electrochemical properties

高通量测序数据再分析在识别结直肠癌患者ERBB2扩增中的价值

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复旦学报（医学版） 2024年第2期51卷 166-171页

作者：沈敏娜张丽陈馨宁黄斐白超刚陈丽萌彭海翔周琰王蓓丽潘柏申郭玮复旦大学附属中山医院检验科上海200032 复旦大学附属中山医院厦门医院检验科厦门361015 上海市宝山区吴淞中心医院检验科上海200940 上海市老年医学中心检验科上海201104 上海顿慧医疗科技发展有限公司上海201615

目的评估未涵盖即ERBB2拷贝数变异(copynumbervariation,CNV)分析的高通量测序(highthroughput sequencing,HTS)数据再分析在识别结直肠癌患者ERBB2扩增中的价值。方法回顾性分析经病理活检确诊为结直肠癌并接受外周血cfDNA高通量测序... 详细信息

目的评估未涵盖即ERBB2拷贝数变异(copynumbervariation,CNV)分析的高通量测序(highthroughput sequencing,HTS)数据再分析在识别结直肠癌患者ERBB2扩增中的价值。方法回顾性分析经病理活检确诊为结直肠癌并接受外周血cfDNA高通量测序样本的检测数据252例。根据经免疫组织化学(immunohistochemistry,IHC)和/或荧光原位杂交(fluorescence in situ hybridization,FISH)判断为ERBB2未扩增样本的HTS数据,计算17号染色体(Chr17)reads数占总reads数的比例范围,初步确定其为识别ERBB2扩增的阈值。根据初步阈值筛选可疑阳性样本,通过数字PCR、IHC和FISH进行验证。结果89例经IHC和/或FISH判定为ERBB2未扩增样本的Chr17 reads数与总reads数的比值为0.239±0.192(0.188~0.299)。以均数的1.25倍0.298作为识别ERBB2扩增的阈值分析其余163例样本数据,发现7例疑似阳性,比值为0.302~0.853。其中5例经IHC和/或FISH判定为阳性,6例经数字PCR验证为阳性,Chr17 reads与总reads数的比值与ERBB2/EIF2C1比值成正相关,相关性好(r2=0.909)。结论再分析未涵盖ERBB2 CNV分析的HTS数据可以初步识别结直肠癌患者的ERBB2扩增。

关键词：高通量测序(HTS) 数字PCR 免疫组织化学(IHC) 荧光原位杂交(FISH) 直肠癌

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成人IgA血管炎肾炎的诊治现状

中华临床免疫和变态反应杂志 2024年第1期18卷 45-50页

作者：胡蓉蓉陈丽萌中国医学科学院、北京协和医院肾内科北京100730

IgA血管炎(IgAV)是一种发病机制尚不明确的血管炎。肾脏是IgA血管炎最常受累的器官之一,且在成人中预后差。目前对于IgA血管炎肾炎(IgAVN)的预后分析策略、优选的治疗方案尚没有统一的指导意见。本文将综述近年来IgAVN临床及病理活动性... 详细信息

IgA血管炎(IgAV)是一种发病机制尚不明确的血管炎。肾脏是IgA血管炎最常受累的器官之一,且在成人中预后差。目前对于IgA血管炎肾炎(IgAVN)的预后分析策略、优选的治疗方案尚没有统一的指导意见。本文将综述近年来IgAVN临床及病理活动性评价及治疗策略等相关研究进展。

关键词： IgA血管炎肾炎成人分型治疗

UNCONDITIONAL ERROR ANALYSIS OF VEMS FOR A GENERAliZED NONliNEAR SCHRODINGER EQUATION

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Journal of Computational Mathematics 2024年第2期42卷 500-543页

作者： meng li Jikun Zhao Shaochun chen School of Mathematics and Statistics Zhengzhou UniversityZhengzhouHenan 450001China

In this work,we focus on the conforming and nonconforming leap-frog virtual element methods for the generalized nonlinear Schrodinger equation,and establish their unconditional stability and optimal error *** constructing a time-discrete system,the error between the solutions of the continuous model and the numerical scheme is separated into the temporal error and the spatial error,which makes the spatial error τ-*** inverse inequalities in the existing conforming and new constructed nonconforming virtual element spaces are utilized to derive the L^(∞)-norm uniform boundedness of numerical solutions without any restrictions on time-space step ratio,and then unconditionally optimal error estimates of the numerical schemes are obtained *** needs to be emphasized is that if we use the pre-existing nonconforming virtual elements,there is no way to derive the L^(∞)-norm uniform boundedness of the functions in the nonconforming virtual element spaces so as to be hard to get the corresponding inverse ***,several numerical examples are reported to confirm our theoretical results.

关键词： Conforming and nonconforming Virtual element methods Leap-frog scheme Generalized nonlinear Schrodinger system Unconditionally optimal error estimates

Aerodynamic Performance of Three Flapping Wings with Unequal Spacing in Tandem Formation

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Journal of Bionic Engineering 2024年第4期21卷 1662-1676页

作者： Min Chang Ziyi Xu Zengshuang chen li li Xueguang meng Unmanned System Research Institute National Key Laboratory of Unmanned Aerial Vehicle TechnologyNorthwestern Polytechnical UniversityXi’an710072People’s Republic of China State Key Laboratory for Strength and Vibration of Mechanical Structures School of Aerospace EngineeringXi’an Jiaotong UniversityXi’an710049People’s Republic of China Xi’an Aeronautics Computing Technique Research Institute Aviation Industry Corporation of ChinaXi’an710076People’s Republic of China

To better understand the aerodynamic reasons for highly organized movements of flying organisms,the three-flapping wing system in tandem formation was studied numerically in this *** from previous relevant studies on the multiple flapping wings that are equally spaced,this study emphasizes the impact of unequal spacing between individuals on the aerodynamics of each individual wing as well as the whole *** is found that swapping the distance between the first and second wing with the distance between the second wing and the rearmost wing does not affect the overall aerodynamic performance,but significantly changes the distribution of aerodynamic benefits across each *** the whole flapping cycle,three effects are at *** narrow channel effect and the downwash effect can promote and weaken the wing lift,respectively,while the wake capture effect can boost the *** also shows that these effects could be manipulated by changing the spacing between adjacent *** findings provide a novel way for flow control in tandem formation flight and are also inspiring for designing the formation flight of bionic aircraft.

关键词： Three flapping wings Unequal spacing Aerodynamic performance Tandem formation

Inhibition of DNA restrictive endonucleases and Taq DNA polymerase by trimalonic acid C_(60)

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Chinese Science Bulletin 2007年第13期52卷 1802-1806页

作者： YANG Xinlin chen Zhe meng XianMei li Bo TAN Xin School of life Science and Technology Eeijing Institute of Technology Eeijing 100081 China

Activities of trimalonic acid fullerene (TMA C_60) on DNA restrictive enzymatic reaction were investigated by using two restrictive endonucleases Hind III and EcoR I and plasmid pEGFP-N1 with single restric-tive site for both enzymes. Meanwhile, TMA C60 was also tested to clarify its effects on polymerase chain reaction (PCR) with the catalyst of Taq DNA polymerase and the template of plasmid pEGFP-N1. The products from restrictive reactions or PCR were detected by agarose gel electrophoresis. It was found that the product amounts from restrictive reactions or PCR decreased significantly with addition of TMA C60. The inhibition by TMA C60 was dose-dependent and IC50 values for reactions of Hind III, EcoR I and PCR were 16.3, 6.0 and 6.0 μmol/L, respectively. Addition of two scavengers of reactive oxygen species (ROS), L-ascorbic acid-2-phosphate ester magnesium and sodium azide at the con-centrations of 2―10 mmol/L did not antagonize the activities of TMA C60 against PCR and two restrictive reactions. However, increase of Taq DNA polymerase amounts in PCR system antagonized the activities of TMA C60. These data implied that TMA C60 was able to inhibit the activities of the three above-mentioned enzymes involved in DNA metabolism, and that this inhibition probably did not correlate to ROS.

关键词：内切核苷酸抑制作用 DNA 聚合酶氧化

A survey of decision making in adversarial games

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Science China(Information Sciences) 2024年第4期67卷 85-112页

作者： Xiuxian li Min meng Yiguang HONG Jie chen College of Electronics and Information Engineering Tongji University Shanghai Research Institute for Intelligent Autonomous Systems

In many practical applications, such as poker, chess, drug interdiction, cybersecurity, and national defense, players often have adversarial stances, i.e., the selfish actions of each player inevitably or intentionally inflict loss or wreak havoc on other players. Therefore, adversarial games are important in realworld applications. However, only special adversarial games, such as Bayesian games, are reviewed in the literature. In this respect, this study aims to provide a systematic survey of three main game models widely employed in adversarial games, i.e., zero-sum normal-form and extensive-form games, Stackelberg(security) games, and zero-sum differential games, from an array of perspectives, including basic knowledge of game models,(approximate) equilibrium concepts, problem classifications, research frontiers,(approximate) optimal strategy-seeking techniques, prevailing algorithms, and practical applications. Finally, promising future research directions are also discussed for relevant adversarial games.

关键词： adversarial games zero-sum games Stackelberg games differential games Nash equilibrium correlated equilibrium regret

CONSERVATIVE CONFORMING AND NONCONFORMING VEMS FOR FOURTH ORDER NONliNEAR SCHRODINGER EQUATIONS WITH TRAPPED TERM

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Journal of Computational Mathematics 2024年第2期42卷 454-499页

作者： meng li Jikun Zhao Zhongchi Wang Shaochun chen School of Mathematics and Statistics Zhengzhou UniversityZhengzhou 450001China School of Computer Science and Engineering Beihang universityBeijing 100083China

This paper aims to construct and analyze the conforming and nonconforming virtual element methods for a class of fourth order nonlinear Schrodinger equations with trapped *** mainly consider three types of virtual elements,including H^(2) conforming virtual element,C^(0) nonconforming virtual element and Morley-type nonconforming virtual *** fully discrete schemes are constructed by virtue of virtual element methods in space and modified Crank-Nicolson method in *** prove the mass and energy conservation,the boundedness and the unique solvability of the fully discrete *** introducing a new type of the Ritz projection,the optimal and unconditional error estimates for the fully discrete schemes are presented and ***,two numerical examples are investigated to confirm our theoretical analysis.

关键词： H^(2)conforming virtual element C^(0)nonconforming virtual element Morleytype nonconforming virtual element Nonlinear Schrodinger equation Conservation Convergence

Effect of particle composition and consolidation degree on the wave-induced liquefaction of soil beds

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Acta Oceanologica Sinica 2024年第2期43卷 11-22页

作者： Zhiyuan chen Yupeng Ren Guohui Xu meng li Shandong Provincial Key Laboratory of Marine Environment and Geological Engineering Ocean University of ChinaQingdao 266100China Marine Ecological Restoration and Smart Ocean Engineering Research Center of Hebei Province Qinhuangdao 066000China Key Laboratory of Marine Environment and Ecology(Ocean University of China) Ministry of EducationQingdao 266100China Key Laboratory of Submarine Geoscience and Prospecting Techniques(Ocean University of China) Ministry of EducationQingdao 266100China

The wave-induced liquefaction of seabed is responsible for causing damage to marine *** composition and consolidation degree are the key factors affecting the pore water pressure response and liquefaction behavior of the seabed under wave *** present study conducted wave flume experiments on silt and silty fine sand beds with varying particle ***,a comprehensive analysis of the differences and underlying reasons for liquefaction behavior in two different types of soil was conducted from both macroscopic and microscopic *** experimental results indicate that the silt bed necessitates a lower wave load intensity to attain the liquefaction state in comparison to the silty fine sand ***,the duration and development depth of liquefaction are greater in the silt *** dissimilarity in liquefaction behavior between the two types of soil can be attributed to the variation in their permeability and plastic deformation *** permeability coefficient and compression modulus of silt are lower than those of silty fine ***,silt is more prone to the accumulation of pore pressure and subsequent liquefaction under external *** research has demonstrated that silt beds with varying consolidation degrees exhibit distinct initial failure ***,a dense bed undergoes shear failure,whereas a loose bed experiences initial liquefaction *** study utilized discrete element simulation to examine the microscopic mechanisms that underlie this phenomenon.

关键词： wave flume liquefaction pore water pressure consolidation permeability experiment discrete element simulation