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10MW高温气冷实验堆反应堆压力容器热电偶贯穿件

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核动力工程 2001年第1期22卷 30-35页

作者：查美生仲朔平陈仁锠清华大学核能技术设计研究院北京102201 上海核工程研究设计院 200233

介绍了 10 MW高温气冷实验堆反应堆压力容器热电偶贯穿件。热电偶贯穿件用于堆芯部件温度的测量，由贯穿筒体、铠装热电偶组件和焊接保护管组成。采用过渡管结构、激光焊和钨极氩弧焊方法，实现两种壁厚相差甚大的铠装热电偶套管和贯穿... 详细信息

介绍了 10 MW高温气冷实验堆反应堆压力容器热电偶贯穿件。热电偶贯穿件用于堆芯部件温度的测量，由贯穿筒体、铠装热电偶组件和焊接保护管组成。采用过渡管结构、激光焊和钨极氩弧焊方法，实现两种壁厚相差甚大的铠装热电偶套管和贯穿筒体的焊接，有效地解决了高温高压下氦气密封的困难。铠装热电偶组件直接贯穿反应堆容器，在容器外采用卡套密封，避免了高温容器内信号的转接。经 ANSYS程序分析计算，热电偶贯穿件的结构设计满足应力强度和抗震要求。经氦检漏试验，热电偶贯穿件泄漏率小于 1× 10－ 7 Pa· m3/s。该热电偶贯穿件现已在反应堆上安装完毕。

关键词：高温气冷堆温度测量热电偶压力容器贯穿件堆芯部件

Transforming growth factor-beta 1 enhances discharge activity of cortical neurons

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Neural Regeneration Research 2025年第2期20卷 548-556页

作者： Zhihui ren Tian Li Xueer Liu Zelin Zhang Xiaoxuan chen Weiqiang chen Kangsheng Li Jiangtao Sheng Department of Microbiology and Immunology Guangdong Provincial Key Laboratory of Infectious Diseases and Molecular ImmunopathologyShantou University Medical CollegeShantouGuangdong ProvinceChina Department of Neurosurgery First Affiliated Hospital of Shantou University Medical CollegeShantouGuangdong ProvinceChina

Transforming growth factor-beta 1(TGF-β1)has been extensively studied for its pleiotropic effects on central nervous system *** neuroprotective or neurotoxic effects of TGF-β1 in specific brain areas may depend on the pathological process and cell types ***-gated sodium channels(VGSCs)are essential ion channels for the generation of action potentials in neurons,and are involved in various neuroexcitation-related ***,the effects of TGF-β1 on the functional properties of VGSCs and firing properties in cortical neurons remain *** this study,we investigated the effects of TGF-β1 on VGSC function and firing properties in primary cortical neurons from *** found that TGF-β1 increased VGSC current density in a dose-and time-dependent manner,which was attributable to the upregulation of Nav1.3 *** VGSC current density and Nav1.3 expression were significantly abolished by preincubation with inhibitors of mitogen-activated protein kinase kinase(PD98059),p38 mitogen-activated protein kinase(SB203580),and Jun NH2-terminal kinase 1/2 inhibitor(SP600125).Interestingly,TGF-β1 significantly increased the firing threshold of action potentials but did not change their firing rate in cortical *** findings suggest that TGF-β1 can increase Nav1.3 expression through activation of the ERK1/2-JNK-MAPK pathway,which leads to a decrease in the firing threshold of action potentials in cortical neurons under pathological ***,this contributes to the occurrence and progression of neuroexcitatory-related diseases of the central nervous system.

关键词： central nervous system cortical neurons ERK firing properties JNK Nav1.3 p38 transforming growth factor-beta 1 traumatic brain injury voltage-gated sodium currents

Advances in Application of Models in Soil Quality Evaluation

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Asian Agricultural Research 2012年第11期4卷 89-93页

作者： SI Zhi-guo WANG Ji-jie YU Yuan-chun LIANG Guan-feng chen chang-ren SHU Hong-lan Forest Resources and Environment Nanjing Forestry University Henan Vocational and Technical College Sichuan Forestry Exploration and Design Institute State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil ScienceChinese Academy of Sciences Jiangsu Water Resources Department Jiangxi University of Finance and Economics

Soil quality is a comprehensive reflection of soil *** the soil quality concept was put forward in the 1970s,the quality of different type soils in different regions have been evaluated through a variety of evaluation methods,but it still lacks universal soil quantity evaluation models and *** this paper,the applications and prospects of grey relevancy comprehensive evaluation model,attribute hierarchical model,fuzzy comprehensive evaluation model,matter-element model,RAGA-based PPC /PPE model and GIS model in soil quality evaluation are reviewed.

关键词： Soil quality Evaluation model Application

Tranylcypromine upregulates Sestrin 2 expression to ameliorate NLRP3-related noise-induced hearing loss

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Neural Regeneration Research 2025年第5期20卷 1483-1494页

作者： Xihang chen Zhifeng chen Menghua Li Weiwei Guo Shuolong Yuan Liangwei Xu chang Lin Xi Shi Wei chen Shiming Yang Senior Department of Otolaryngology Head and Neck Surgery Chinese PLA General HospitalChinese PLA Medical SchoolBeijingChina State Key Laboratory of Hearing and Balance Science BeijingChina National Clinical Research Center for Otolaryngologic Diseases BeijingChina Key Laboratory of Hearing Science Ministry of EducationBeijingChina Beijing Key Laboratory of Hearing Impairment Prevention and Treatment BeijingChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of Fujian Medical UniversityFuzhouFujian ProvinceChina Department of Otolaryngology Head and Neck Surgery The 940th Hospital of Joint Logistics Support Force of Chinese PLALanzhouGansu ProvinceChina Key Laboratory of Tropical Biological Resources of Ministry of Education School of Pharmaceutical SciencesHainan UniversityHaikouHainan ProvinceChina Academician Workstation of Hainan University School of Pharmaceutical SciencesYazhou BaySanyaHainan ProvinceChina

Noise-induced hearing loss is the primary non-genetic factor contributing to auditory ***,there are currently no effective pharmacological interventions for patients with noise-induced hearing ***,we present evidence suggesting that the lysine-specific demethylase 1 inhibitor–tranylcypromine is an otoprotective agent that could be used to treat noise-induced hearing loss,and elucidate its underlying regulatory *** established a mouse model of permanent threshold shift hearing loss by exposing the mice to white broadband noise at a sound pressure level of 120 d B for 4 *** found that tranylcypromine treatment led to the upregulation of Sestrin2(SESN2)and activation of the autophagy markers light chain 3B and lysosome-associated membrane glycoprotein 1 in the cochleae of mice treated with *** noise exposure group treated with tranylcypromine showed significantly lower average auditory brainstem response hearing thresholds at click,4,8,and 16 k Hz frequencies compared with the noise exposure group treated with *** findings indicate that tranylcypromine treatment resulted in increased SESN2,light chain 3B,and lysosome-associated membrane glycoprotein 1 expression after noise exposure,leading to a reduction in levels of 4-hydroxynonenal and cleaved caspase-3,thereby reducing noise-induced hair cell ***,immunoblot analysis demonstrated that treatment with tranylcypromine upregulated SESN2 expression via the autophagy *** treatment also reduced the production of NOD-like receptor family pyrin domaincontaining 3(NLRP3)*** conclusion,our results showed that tranylcypromine treatment ameliorated cochlear inflammation by promoting the expression of SESN2,which induced autophagy,thereby restricting NLRP3-related inflammasome signaling,alleviating cochlear hair cell loss,and protecting hearing *** findings suggest that inhibiting lysine-specific demethylase 1 is a

关键词： 4-hydroxynonenal apoptosis autophagy cleaved caspase-3 inflammation NOD-like receptor family pyrin domain-containing 3(NLRP3) noise-induced hearing loss oxidative stress Sestrin2 tranylcypromine

Gradient‑Layered MXene/Hollow Lignin Nanospheres Architecture Design for Flexible and Stretchable Supercapacitors

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Nano-Micro Letters 2025年第2期17卷 447-462页

作者： Haonan Zhang cheng Hao Tongtong Fu Dian Yu Jane Howe Kaiwen chen Ning Yan Hao ren Huamin Zhai Jiangsu Provincial Key Lab of Sustainable Pulp and Paper Technology and Biomass Materials NanJing Forestry UniversityNanjing 210037People’s Republic of China Department of Chemical Engineering and Applied Chemistry University of Toronto200 College StreetTorontoON M5S 3E5Canada Department of Materials Science and Engineering University of Toronto184 College StreetTorontoON M5S 3E4Canada College of Materials Science and Engineering Nanjing Forestry UniversityNanjing 210037People’s Republic of China

With the rapid development of flexible wearable electronics,the demand for stretchable energy storage devices has *** this work,a novel gradient-layered architecture was design based on single-pore hollow lignin nanospheres(HLNPs)-intercalated two-dimensional transition metal carbide(Ti_(3)C_(2)T_(x) MXene)for fabricating highly stretchable and durable *** depositing and inserting HLNPs in the MXene layers with a bottom-up decreasing gradient,a multilayered porous MXene structure with smooth ion channels was constructed by reducing the overstacking of MXene ***,the micro-chamber architecture of thin-walled lignin nanospheres effectively extended the contact area between lignin and MXene to improve ion and electron accessibility,thus better utilizing the pseudocapacitive property of *** these strategies effectively enhanced the capacitive performance of the *** addition,HLNPs,which acted as a protective phase for MXene layer,enhanced mechanical properties of the wrinkled stretchable electrodes by releasing stress through slip and deformation during the stretch-release cycling and greatly improved the structural integrity and capacitive stability of the *** electrodes and symmetric flexible all-solid-state supercapacitors capable of enduring 600%uniaxial tensile strain were developed with high specific capacitances of 1273 mF cm^(−2)(241 F g^(−1))and 514 mF cm^(−2)(95 F g^(−1)),***,their capacitances were well preserved after 1000 times of 600%stretch-release *** study showcased new possibilities of incorporating biobased lignin nanospheres in energy storage devices to fabricate stretchable devices leveraging synergies among various two-dimensional nanomaterials.

关键词： Hollow lignin nanospheres MXene Gradient-layered architecture Wrinkled electrodes Stretchable supercapacitors

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空间SiC反射镜背部中心支撑特性

光子学报 2017年第2期46卷 22-31页

作者：包奇红沙巍陈长征任建岳中国科学院长春光学精密机械与物理研究所长春130033 中国科学院大学北京100039

基于特定的轻量化形式和支撑结构,采用有限元方法研究了口径为500mm的空间SiC反射镜的背部中心支撑特性.通过分析镜体结构参量对反射镜性能的影响,确定了最佳的支撑孔直径与反射镜口径的比例为0.23,指出对不同口径的反射镜需通过优化确... 详细信息

基于特定的轻量化形式和支撑结构,采用有限元方法研究了口径为500mm的空间SiC反射镜的背部中心支撑特性.通过分析镜体结构参量对反射镜性能的影响,确定了最佳的支撑孔直径与反射镜口径的比例为0.23,指出对不同口径的反射镜需通过优化确定最佳的背部形状,当重力沿径向作用时,增大支撑深度有利于提高面形准确度.支撑结构分析结果表明,柔性连接件底部螺栓圆半径是影响温变载荷工况下的面形准确度和反射镜组件的一阶固有频率的关键因素,要确定最佳的底部螺栓圆半径需综合考虑面形准确度和结构基频两方面的指标要求;背部中心支撑的反射镜面形准确度受外界装配应力的影响较小,且对柔性连接件切槽深度的变化不敏感;支撑长度主要影响结构的动态刚度,减小支撑长度能提高反射镜组件的一阶固有频率.最后确定了空间SiC反射镜背部中心支撑的最大适用口径为750mm,对口径小于750mm的SiC反射镜在结构允许的前提下采用背部中心支撑均能满足设计要求.

关键词：空间光学空间反射镜有限元分析背部中心支撑支撑特性适用口径

Statistical analysis on the validity of the cold plasma approximation for chorus waves based on Van Allen Probe observations and their effects on radiation belt electrons

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Earth and Planetary Physics 2025年第1期9卷 159-170页

作者： AoJun ren Jiang Yu Jing Wang ZuZheng chen XiaoMan Liu Planetary Environmental and Astrobiological Research Laboratory(PEARL) School of Atmospheric SciencesSun Yat-sen UniversityZhuhai Guangdong 519000China

Theoretical analysis has demonstrated that the dispersion relation of chorus waves plays an essential role in the resonant interaction and energy transformation between the waves and magnetospheric *** quantitative analyses often simplified the chorus dispersion relation by using the cold plasma ***,the applicability of the cold plasma assumption is doubtful,especially during geomagnetic *** here present a systematic statistical analysis on the validity of the cold plasma dispersion relation of chorus waves based on observations from the Van Allen Probes over the period from 2012 to *** statistical results show that the observed magnetic field intensities deviate substantially from those calculated from the cold plasma dispersion relation and that they become more pronounced with an increase in geomagnetic activity or a decrease in background plasma *** region with large deviations is mainly concentrated in the nightside and expands in both the radial and azimuthal directions as the geomagnetic activity increases or the background plasma density *** addition,the bounce-averaged electron scattering rates are computed by using the observed and cold plasma dispersion relation of chorus *** with usage of the cold plasma dispersion relation,usage of the observed dispersion relation considerably lowers the minimum resonant energy of electrons and lowers the scattering rates of electrons above tens of kiloelectronvolts but enhances those ***,these differences are more pronounced with the enhancement of geomagnetic activity or the decrease in background plasma density.

关键词： chorus waves cold plasma approximation dispersion relations scattering rates

基于多元目标的水利风景区开发规划引导性研究

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水生态学杂志 2010年第2期3卷 138-141页

作者：陈昌仁于涛贾蔚南京林业大学江苏南京210037 江苏省水利厅河道局江苏南京210029 南京市规划局江苏南京210005

新时期,在强调水资源可持续利用的总体战略目标下,水利事业已将水土资源的生态保护、娱乐利用、旅游观光作为发展方向和任务之一,把水利风景区的开发建设纳入了重要工作内容。水利风景区的开发目标具有多元特点,其规划具有很强的综合性... 详细信息

新时期,在强调水资源可持续利用的总体战略目标下,水利事业已将水土资源的生态保护、娱乐利用、旅游观光作为发展方向和任务之一,把水利风景区的开发建设纳入了重要工作内容。水利风景区的开发目标具有多元特点,其规划具有很强的综合性和多重复合的跨学科特征,是水利风景旅游事业发展面临的重要课题。在阐述水利风景区开发的多元目标基础上,对其科学规划的意义、原则、编制要求及导则等方面进行研究,并明确提出基于水资源保护、自然与景观资源保护、生态环境修复等多元目标的水利风景区规划引导整体框架。

关键词：多元目标水利风景区开发规划

MXene Hybridized Polymer with Enhanced Electromagnetic Energy Harvest for Sensitized Microwave Actuation and Self‑Powered Motion Sensing

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Nano-Micro Letters 2025年第3期17卷 265-279页

作者： Yu‑Ze Wang Yu‑chang Wang Ting‑Ting Liu Quan‑Liang Zhao chen‑Sha Li Mao‑Sheng Cao School of Materials Science and Engineering Beijing Institute of TechnologyBeijing 100081People’s Republic of China School of Materials Science and Engineering Peking UniversityBeijing 100871People’s Republic of China School of Mechanical and Material Engineering North China University of TechnologyBeijing 100144People’s Republic of China Key Laboratory of Functional Inorganic Material Chemistry Ministry of Education of the People’s Republic of ChinaHeilongjiang UniversityHarbin 150080People’s Republic of China

Polymeric microwave actuators combining tissue-like softness with programmablemicrowave-responsive deformation hold great promise for mobile intelligentdevices and bionic soft robots. However, their application is challenged by restricted electromagneticsensitivity and intricate sensing coupling. In this study, a sensitized polymericmicrowave actuator is fabricated by hybridizing a liquid crystal polymer with Ti3C2Tx(MXene). Compared to the initial counterpart, the hybrid polymer exhibits unique spacechargepolarization and interfacial polarization, resulting in significant improvements of230% in the dielectric loss factor and 830% in the apparent efficiency of electromagneticenergy harvest. The sensitized microwave actuation demonstrates as the shortenedresponse time of nearly 10 s, which is merely 13% of that for the initial shape memory polymer. Moreover, the ultra-low content of MXene (upto 0.15 wt%) benefits for maintaining the actuation potential of the hybrid polymer. An innovative self-powered sensing prototype that combinesdriving and piezoelectric polymers is developed, which generates real-time electric potential feedback (open-circuit potential of ~ 3 mV) duringactuation. The polarization-dominant energy conversion mechanism observed in the MXene-polymer hybrid structure furnishes a new approachfor developing efficient electromagnetic dissipative structures and shows potential for advancing polymeric electromagnetic intelligent devices.

关键词： Microwave absorption Electromagnetic response Energy harvest Self-sensing Soft actuator