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Polygonal finite element-based content-aware image warping

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Computational Visual Media 2023年第2期9卷 367-383页

作者： juan cao Xiaoyi Zhang Jiannan Huang Yongjie Jessica Zhang School of Mathematical Sciences Xiamen UniversityXiamen 361005China Fujian Provincial Key Laboratory of Mathematical Modeling and High-Performance Scientific Computation Xiamen UniversityXiamen 361005China Department of Mechanical Engineering Carnegie Mellon UniversityPittsburghPA 15213USA

Mesh-based image warping techniques typically represent image deformation using linear functions on triangular meshes or bilinear functions on rectangular meshes.This enables simple and efficient implementation,but in turn,restricts the representation capability of the deformation,often leading to unsatisfactory warping results.We present a novel,flexible polygonal finite element(poly-FEM)method for content-aware image warping.Image deformation is represented by high-order poly-FEMs on a content-aware polygonal mesh with a cell distribution adapted to saliency information in the source image.This allows highly adaptive meshes and smoother warping with fewer degrees of freedom,thus significantly extending the flexibility and capability of the warping representation.Benefiting from the continuous formulation of image deformation,our polyFEM warping method is able to compute the optimal image deformation by minimizing existing or even newly designed warping energies consisting of penalty terms for specific transformations.We demonstrate the versatility of the proposed poly-FEM warping method in representing different deformations and its superiority by comparing it to other existing state-ofthe-art methods.

关键词： image warping finite element method(FEM) polygonal element mesh generation

Mapping rapeseed planting areas using an automatic phenology-and pixel-based algorithm(APPA) in Google Earth Engine

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The Crop Journal 2022年第5期10卷 1483-1495页

作者： Jichong Han Zhao Zhang juan cao Yuchuan Luo Academy of Disaster Reduction and Emergency Management Ministry of Emergency Management&Ministry of Education School of National Safety and Emergency ManagementBeijing Normal UniversityBeijing 100875China

The timely and rapid mapping of rapeseed planting areas is desirable for national food security. Most current rapeseed mapping methods depend strongly on images with good observations obtained during the flowering stages. Although vegetation indices have been proposed to identify the rapeseed flowering stage in some areas, automatically mapping rapeseed planting areas in large regions is still challenging.We developed an automatic phenology-and pixel-based algorithm(APPA) by integrating Landsat 8 and Sentinel-1 satellite data. We found that the Normalized Rapeseed Flowering Index shows unique spectral characteristics during the flowering and post-flowering periods, which distinguish rapeseed parcels from other land-use types(urban, water, forest, grass, maize, wheat, barley, and soybean). To verify the robustness of APPA, we applied APPA to seven areas in five rapeseed-producing countries with flowering images unavailable. The rapeseed maps by APPA showed consistently high accuracies with producer accuracies of 0.87–0.93 and F-scores of 0.92–0.95 based on 4503 verification samples. They showed high spatial consistency at the pixel level with the land cover Scientific Expertise Centres(SEC) map in France,Crop Map of England in United Kingdom, national-scale crop-and land-cover map of Germany, and Annual Crop Inventory in Canada at the pixel level. We propose APPA as a highly promising method for automatically and efficiently mapping rapeseed areas.

关键词： Automatic mapping Spectral indices Polarization Phenology Rapeseed

Cellular and molecular regulation of innate inflammatory responses

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Cellular & Molecular Immunology 2016年第6期13卷 711-721页

作者： juan Liu Xuetao cao National Key Laboratory of Medical Immunology & Institute of Immunology Second Military Medical University Shanghai 200433 China National Key Laboratory of Medical Molecular Biology Department of Immunology & Center for Immunotherapy Institute of Basic Medical Sciences Peking Union Medical College Chinese Academy of Medical Sciences Beijing 100005 China

Innate sensing of pathogens by pattern-recognition receptors （PRRs） plays essential roles in the innate discrimination between self and non-self components, leading to the generation of innate immune defense and inflammatory responses. The initiation, activation and resolution of innate inflammatory response are mediated by a complex network of interactions among the numerous cellular and molecular components of immune and non- immune system. While a controlled and beneficial innate inflammatory response is critical for the elimination of pathogens and maintenance of tissue homeostasis, dysregulated or sustained inflammation leads to pathological conditions such as chronic infection, inflammatory autoimmune diseases. In this review, we discuss some of the recent advances in our understanding of the cellular and molecular mechanisms for the establishment and reJzulation of innate immunity and inflammatory responses.

关键词： dendritic cells inflammation innate lymphoid cells innate signaling pattern-recognition receptors （PRRs）

Exosome-transported IncRNA H19 regulates insulin-like growth factor-1 via the H19/let-7a/insulin-like growth factor-1 receptor axis in ischemic stroke

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Neural Regeneration Research 2023年第6期18卷 1316-1320页

作者： Jue Wang Bin cao Yan Gao Yu-Hua Chen juan Feng Department of Neurology Shengjing Hospital of China Medical UniversityShenyangLiaoning ProvinceChina Department of Developmental Cell Biology Key Laboratory of Cell BiologyMinistry of Public Healthand Key Laboratory of Medical Cell BiologyMinistry of EducationChina Medical UniversityShenyangLiaoning ProvinceChina

LncRNA(long non-coding RNA) H19 is a transcript of the H19 gene that is expressed during embryogenesis.We previously discove red a role for circular lncRNA H19 in the onset and prognosis of cerebral ischemic stroke.In this study,we used serum from patients with ischemic stroke,and mouse and cell culture models to elucidate the roles of plasma and neuronal exosomes in the regulatory effect of lncRNA H19 on insulin-like growth factor-1 and its mechanism in ischemic stroke,using western blotting,quantitative real-time polymerase chain reaction,and enzyme-linked immunosorbent assays.Plasma exosomal IncRNA H19 was negatively associated with blood levels of insulin-like growth factor-1 in samples from patients with cerebral ischemic stroke.In a mouse model,levels of exosomal IncRNA H19 were positively correlated with plasma and cerebral lncRNA H19.In a cell co-culture model,we confirmed that IncRNA H19 was transported from neuro ns to astrocytes by exosomes to induce downregulation of insulin-like growth factor-1 through the H19/let-7 a/insulin-like growth factor-1 receptor axis.This study provides the first evidence for the transpo rtation of IncRNA H19 by exosomes and the relationship between IncRNA H19 and insulinlike growth factor-1.

关键词： cerebral ischemia exosomes H19 insulin-like growth factor-1 insulin-like growth factor 1 receptor ischemic stroke long non-coding RNA

Metabolic control of T-cell immunity via epigenetic mechanisms

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Cellular & Molecular Immunology 2018年第3期15卷 203-205页

作者： Xiaomin Zhang juan Liu Xuetao cao National Key Laboratory of Medical Immunology&Institute of Immunology Second Military Medical UniversityShanghai200433China Department of Immunology and Center for Immunotherapy Institute of Basic Medical SciencesChinese Academy of Medical SciencesBeijing100005China

Metabolism has been increasingly considered to play an important role in inflammation and immunity via modulating cellular signaling and transcriptional networks.1 Dysregulation of metabolic enzymes or mediators is increasingly linked to clinical diseases,such as type I diabetes,gliomas and breast cancer.2,3 Numerous metabolic sensors,such as AMP-mediated protein kinase,mammalian target of rapamycin complex1 and hypoxia-induced factor 1α(HIF-1α),have been shown to regulate immunological responses,such as T-cell activation and macrophage polarization,via modulating the property and activity of signaling pathways.4,5 Moreover,emerging evidence suggests that intermediates from multiple metabolic pathways are important in orchestrating transcriptional and epigenetic programs.This interaction between metabolic and epigenetic pathways is crucial for coordinating cellular immunological events in response to extracellular stimuli,such as infection,injury and stress,leading to varied biological and pathological outcomes.

关键词： immunity epigenetic inflammation

Cooper instability and superconductivity of the Penrose lattice

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Science China(Physics,Mechanics & Astronomy) 2022年第8期65卷 110-120页

作者： Yu-Bo Liu juan-juan Hao Yongyou Zhang Ye cao Wei-Qiang Chen Fan Yang School of Physics Beijing Institute of TechnologyBeijing100081China Department of Physics Southern University of Science and TechnologyShenzhen518055China Shenzhen Institute for Quantum Science and Engineering Southern University of Science and TechnologyShenzhen518055China Shenzhen Key Laboratory of Advanced Quantum Functional Materials and Devices Southern University of Science and TechnologyShenzhen518055China

Bulk superconductivity(SC) has recently been observed in the Al-Zn-Mg quasicrystal(QC). To settle several fundamental issues of the SC on the QC, we use an attractive Hubbard model to perform a systematic study on the Penrose lattice. The first issue is the Cooper instability of the QC, i.e., no Fermi surface under an infinitesimal attractive interaction. Starting from the two-electron problem outside a filled Fermi sea, we analytically prove that an infinitesimal Hubbard attraction can lead to the Cooper instability as long as the density of the state is nonzero at the Fermi level. The findings provide a basis for the SC on the QC. Our numerical results show that the Cooper pairing always takes place between two time-reversal states, satisfying Anderson’s theorem. On this theorem, we perform a mean-field(MF) study at zero and finite temperatures. The MF study shows that an arbitrarily weak attraction can lead to a pairing order, with the resulting pairing state being well described by the Bardeen-Cooper-Schrieffer theory and the thermal dynamic behaviors being well consistent with the experimental results. The second issue is about the superfluid density on the QC without translational symmetry. Our findings clarify that although the normal state of the system locates at the critical point of the metal-insulator transition, the pairing state exhibits a real SC, carrying finite superfluid density that can be verified by the Meissner effect. This finding is consistent with the experiment results. This study also reveals that the properties of the SC on the Penrose lattice are universal for all QCs.

关键词： superconductivity quasicrystal cooper instability

Construction of nanocarriers based on nucleic acids and their applications in nanobiology delivery systems

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National Science Review 2022年第5期9卷 181-195页

作者： Yingshu Guo Xiuping cao Xiaofei Zheng Sk Jahir Abbas juan Li Weihong Tan Shandong Provincial Key Laboratory of Molecular Engineering School of Chemistry and Chemical EngineeringQilu University of Technology (Shandong Academy of Sciences) School of Chemistry and Chemical Engineering Linyi University Institute of Molecular Medicine State Key Laboratory of Oncogenes and Related Genes Renji Hospital Shanghai Jiao Tong University School of MedicineCollege of Chemistry and Chemical Engineering Shanghai Jiao Tong University Institute of Cancer and Basic Medicine Chinese Academy of Sciences The Cancer Hospital of the University of Chinese Academy of Sciences

In recent years,nanocarriers based on nucleic acids have emerged as powerful and novel nanocarriers that are able to meet the demand for cancer-cell-specific targeting.Functional dynamics analysis revealed good bio compatibility,low toxicity and programmable structures,and their advantages include controllable size and modifiability.The development of novel hybrids has focused on the distinct roles of biosensing,drug and gene delivery,vaccine transport,photosensitization,counteracting drug resistance and functioning as carriers and logic gates.This review is divided into three parts:(ⅰ) DNA nanocarriers,(ⅱ) RNA nanocarriers and(ⅲ) DNA/RNA hybrid nanocarriers and their applications in nanobiology delivery systems.We also provide perspectives on possible future directions for growth in this field.

关键词： nanocarriers based on nucleic acids biosensing targeted delivery cell

Spatiotemporal patterns of winter wheat phenology and its climatic drivers based on an improved pDSSAT model

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Science China Earth Sciences 2021年第1期64卷 2144-2160页

作者： Yuchuan LUO Zhao ZHANG Liangliang ZHANG juan cao Academy of Disaster Reduction and Emergency Management Minsitry of Emergency Management&Ministry of Education School of National Safety and Emergency ManagementBeijing Normal UniversityBeijing100875China

Acquiring spatiotemporal patterns of phenological information and its drivers is essential for understanding the response of crops to climate change and implementing adaptation measures.However,current approaches to obtain phenology and analyse its drivers have deficiencies such as sparse observations,excessive dependence of remote sensing inversion on sensors,and inevitable difficulties in upscaling site-based crop models into larger regions.Based on the Wang-Engel temperature response function,we improved the Crop Estimation through Resource and Environment Synthesis-Wheat(CERES-Wheat)model.First,we calibrated the model at the regional scale and evaluated its performance.Furthermore,the spatiotemporal changes in winter wheat phenology in China from 2000 to 2015 were analysed.The results showed that the improved model significantly enhanced the simulation accuracy of the anthesis and maturity dates by averages of 13%and 12%in most planting areas,especially in the Yunnan-Guizhou Plateau(YG)with improvements of 26%and 28%.The simulated phenology of winter wheat grown in a colder environment(e.g.,the average temperatures during the vegetative growth period range from 0 to 5℃ and from 15 to 20°C,and the reproductive growth period ranges from 10 to 15°C)also notably improved.These results confirmed that the original temperature response function indeed had limitations.Further analyses revealed that the key phenological dates and growth periods over the past 16 years were dominantly advanced and shortened.Specifically,the anthesis date,vegetative growth period(VGP),and reproductive growth period(RGP)indicated obviously spatial characteristics.For example,the anthesis date and VGP in the North China Plain(NCP)and the Middle-Lower Yangtze Plain(YZ)and the RGP in northwestern China(NW)showed opposite trends of delay and prolongation as comparing with the dominant patterns.Sensitivity analysis indicated that the key phenological dates and growth periods were advanced and shortened as the minimum(T_(min))and maximum temper

关键词： Winter wheat Phenology Temperature response function Spatiotemporal patterns pDSSAT

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1960年以来雄安新区平均和极端气温变化（英文）

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Atmospheric and Oceanic Science Letters 2018年第3期11卷 246-254页

作者： QIAN Cheng cao Li-juan CAS Key Laboratory of Regional Climate-Environment for Temperate East Asia Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina University of Chinese Academy of Science BeijingChina National Meteorological Information Center China Meteorological AdministrationBeijingChina

如何建设雄安新区是时下重要需求,公众也迫切想了解它的历史气候变化。然而,这方面的信息匮乏,也难以从全球或者大区域的研究中获取精准的信息,因为气候变化具有典型的区域特色。本文基于均一化的逐日气温数据,研制了1960年以来雄安新... 详细信息

如何建设雄安新区是时下重要需求,公众也迫切想了解它的历史气候变化。然而,这方面的信息匮乏,也难以从全球或者大区域的研究中获取精准的信息,因为气候变化具有典型的区域特色。本文基于均一化的逐日气温数据,研制了1960年以来雄安新区的连续数据,进而分析了它的平均和极端气温变化趋势。结果表明:1960年以来,平均气温显著升高,1998年至今变暖没有停滞;极端高(低)温的频率总体显著增加(减小)。与周边的京津冀和华北区域平均相比,雄安新区的气温变化幅度更大,需要绿色发展。

关键词：雄安新区气候变化线性趋势平均气温极端气温