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怀化医专学报 2006年第2期5卷 1-5页

作者： cai xiao - hua wu ying- hua Department of pharmaceuticals Huaihua Medical College Huaihua 418000

Bioinspired smart dual-layer hydrogels system with synchronous solar and thermal radiation modulation for energy-saving all-season temperature regulation

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Journal of Energy Chemistry 2025年第2期101卷 175-190页

作者： Meng-Chen huang Chao-hua Xue Zhongxue Bai Jun Cheng Yong-Gang wu Chao-Qun Ma Li Wan Long Xie Hui-Di Wang Bing-ying Liu xiao-Jing Guo College of Bioresources Chemical and Materials Engineering Shaanxi University of Science & Technology School of Manufacture Science and Engineering Key Laboratory of Testing Technology for Manufacturing Process Ministry of Education Southwest University of Science and Technology School of Life Science and Engineering Southwest University of Science and Technology Northwest Institute for Nonferrous Metal Research Shaanxi Key Laboratory of Biomedical Metal Materials

All-season thermal management with zero energy consumption and emissions is more crucial to global decarbonization over traditional energy-intensive cooling/heating ***,the static single thermal management for cooling or heating fails to self-regulate the temperature in dynamic seasonal temperature ***,inspired by the dual-temperature regulation function of the fur color changes on the backs and abdomens of penguins,a smart thermal management composite hydrogel(PNA@H-PM Gel) system was subtly created though an "on-demand" dual-layer structure design *** PNA@H-PM Gel system features synchronous solar and thermal radiation modulation as well as tunable phase transition temperatures to meet the variable seasonal thermal requirements and energy-saving demands via self-adaptive radiative cooling and solar heating ***,this system demonstrates superb modulations of both the solar reflectance(ΔR=0.74) and thermal emissivity(ΔE=0.52) in response to ambient temperature changes,highlighting efficient temperature regulation with average radiative cooling and solar heating effects of 9.6℃ in summer and 6.1℃ in winter,***,compared to standard building baselines,the PNA@H-PM Gel presents a more substantial energy-saving cooling/heating potentials for energy-efficient buildings across various regions and *** novel solution,inspired by penguins in the real world,will offer a fresh approach for producing intelligent,energy-saving thermal management materials,and serve for temperature regulation under dynamic climate conditions and even throughout all seasons.

关键词： Energy-saving Radiative cooling Self-adaptive thermal management Spectral modulation Thermochromic hydrogel

Infiltration by monocytes of the central nervous system and its role in multiple sclerosis: reflections on therapeutic strategies

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Neural Regeneration Research 2025年第3期20卷 779-793页

作者： Guangyong Zhang Qing Yao Chubing Long Pengcheng Yi Jiali Song Luojia wu Wei Wan Xiuqin Rao Yue Lin Gen Wei Jun ying Fuzhou hua Department of Anesthesiology the Second Affiliated Hospital of Nanchang UniversityNanchangJiangxi ProvinceChina Key Laboratory of Anesthesiology of Jiangxi Province NanchangJiangxi ProvinceChina

Mononuclear macrophage infiltration in the central nervous system is a prominent feature of neuroinflammation. Recent studies on the pathogenesis and progression of multiple sclerosis have highlighted the multiple roles of mononuclear macrophages in the neuroinflammatory process. Monocytes play a significant role in neuroinflammation, and managing neuroinflammation by manipulating peripheral monocytes stands out as an effective strategy for the treatment of multiple sclerosis, leading to improved patient outcomes. This review outlines the steps involved in the entry of myeloid monocytes into the central nervous system that are targets for effective intervention: the activation of bone marrow hematopoiesis, migration of monocytes in the blood, and penetration of the blood–brain barrier by monocytes. Finally, we summarize the different monocyte subpopulations and their effects on the central nervous system based on phenotypic differences. As activated microglia resemble monocyte-derived macrophages, it is important to accurately identify the role of monocyte-derived macrophages in disease. Depending on the roles played by monocyte-derived macrophages at different stages of the disease, several of these processes can be interrupted to limit neuroinflammation and improve patient prognosis. Here, we discuss possible strategies to target monocytes in neurological diseases, focusing on three key aspects of monocyte infiltration into the central nervous system, to provide new ideas for the treatment of neurodegenerative diseases.

关键词： blood–brain barrier macrophages monocytes multiple sclerosis neuroinflammation review therapy

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基于轨迹集的衍生扩展目标多伯努利滤波算法

控制与决策 2025年第03期40卷 1024-1034页

作者：杨英壮蔡如华吴孙勇刘锦新桂林电子科技大学数学与计算科学学院桂林电子科技大学广西精密导航技术与应用实验室

针对扩展目标多伯努利滤波器(ECBMeMBer)在复杂环境下对衍生扩展目标跟踪性能严重下降以及无法提取目标轨迹的问题,提出一种基于轨迹随机有限集(Trajectory RFS)的衍生扩展目标多伯努利滤波算法(STCBMeMBer).首先,利用轨迹多伯努利RFS(T... 详细信息

针对扩展目标多伯努利滤波器(ECBMeMBer)在复杂环境下对衍生扩展目标跟踪性能严重下降以及无法提取目标轨迹的问题,提出一种基于轨迹随机有限集(Trajectory RFS)的衍生扩展目标多伯努利滤波算法(STCBMeMBer).首先,利用轨迹多伯努利RFS(Trajectory MBer-RFS)描述多扩展目标的轨迹序列,从而为扩展目标提供连续的轨迹信息;其次,提出一种多伯努利衍生模型,通过原始扩展目标的航向角与衍生扩展目标的偏转角之间的三角函数关系式建立不同衍生扩展目标的运动方程与动力学转移模型,从而实现对衍生扩展目标质心状态与外形状态的联合估计;随后,基于轨迹MBer-RFS和所提出的多伯努利衍生模型推导并提出S-TCBMeMBer滤波器,并在线性高斯条件下给出伽玛高斯逆威沙特(GGIW)混合实现.仿真结果表明,所提出算法在杂波、漏检和噪声共存的环境下能够对衍生扩展目标进行有效跟踪,并提取扩展目标完整的轨迹信息.

关键词：轨迹随机有限集衍生扩展目标多伯努利航向角偏转角伽玛高斯逆威沙特

MACLSTM: A Weather Attributes Enabled Recurrent Approach to Appliance-Level Energy Consumption Forecasting

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Computers, Materials & Continua 2025年第2期82卷 2969-2984页

作者： Ruoxin Li Shaoxiong wu Fengping Deng Zhongli Tian hua cai Xiang Li Xu Xu Qi Liu NARI-TECH Nanjing Control System Co. Ltd.Nanjing211106China School of Software Nanjing University of Information Science&TechnologyNanjing210044China Jiangsu Province Engineering Research Center of Advanced Computing and Intelligent Services Nanjing210044China

Studies to enhance the management of electrical energy have gained considerable momentum in recent years. The question of how much energy will be needed in households is a pressing issue as it allows the management plan of the available resources at the power grids and consumer levels. A non-intrusive inference process can be adopted to predict the amount of energy required by appliances. In this study, an inference process of appliance consumption based on temporal and environmental factors used as a soft sensor is proposed. First, a study of the correlation between the electrical and environmental variables is presented. Then, a resampling process is applied to the initial data set to generate three other subsets of data. All the subsets were evaluated to deduce the adequate granularity for the prediction of the energy demand. Then, a cloud-assisted deep neural network model is designed to forecast short-term energy consumption in a residential area while preserving user privacy. The solution is applied to the consumption data of four appliances elected from a set of real household power data. The experiment results show that the proposed framework is effective for estimating consumption with convincing accuracy.

关键词： Electrical load forecasting cloud computing smart grid weather attributes energy consumption time-series analysis

Pharmacological targeting cGAS/STING/NF-κB axis by tryptanthrin induces microglia polarization toward M2 phenotype and promotes functional recovery in a mouse model of spinal cord injury

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Neural Regeneration Research 2025年第11期20卷 3287-3301页

作者： Ziwei Fan Mengxian Jia Jian Zhou Zhoule Zhu Yumin wu xiaowu Lin Yiming Qian Jiashu Lian Xin hua Jianhong Dong Zheyu Fang Yuqing Liu Sibing Chen Xiumin Xue Juanqing Yue Minyu Zhu ying Wang Zhihui huang Honglin Teng Department of Orthopedics(Spine Surgery) the First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiang ProvinceChina School of Pharmacy Hangzhou Normal UniversityHangzhouZhejiang ProvinceChina Department of Neurology The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiang ProvinceChina Department of Pathology Affiliated Hangzhou First People’s HospitalSchool of MedicineWestlake UniversityHangzhouZhejiang ProvinceChina Department of Clinical Research Center Affiliated Hangzhou First People’s HospitalSchool of MedicineWestlake UniversityHangzhouZhejiang ProvinceChina

The M1/M2 phenotypic shift of microglia after spinal cord injury plays an important role in the regulation of neuroinflammation during the secondary injury phase of spinal cord *** of shifting microglia polarization from M1(neurotoxic and proinflammatory type)to M2(neuroprotective and anti-inflammatory type)after spinal cord injury appears to be *** possesses an anti-inflammatory biological ***,its roles and the underlying molecular mechanisms in spinal cord injury remain *** this study,we found that tryptanthrin inhibited microglia-derived inflammation by promoting polarization to the M2 phenotype in *** promoted M2 polarization through inactivating the cGAS/STING/NF-κB ***,we found that targeting the cGAS/STING/NF-κB pathway with tryptanthrin shifted microglia from the M1 to M2 phenotype after spinal cord injury,inhibited neuronal loss,and promoted tissue repair and functional recovery in a mouse model of spinal cord ***,using a conditional co-culture system,we found that microglia treated with tryptanthrin suppressed endoplasmic reticulum stress-related neuronal *** together,these results suggest that by targeting the cGAS/STING/NF-κB axis,tryptanthrin attenuates microglia-derived neuroinflammation and promotes functional recovery after spinal cord injury through shifting microglia polarization to the M2 phenotype.

关键词： cGAS/STING functional recovery microglia neuroinflammation neuroprotection nuclear factor-κB polarization spinal cord injury tryptanthrin

The GECAM ground search system for gamma-ray transients

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Science China(Physics,Mechanics & Astronomy) 2025年第3期68卷 161-174页

作者： Ce cai Yan-Qiu Zhang Shao-Lin Xiong Ping Wang Jian-Hui Li xiao-Bo Li Cheng-Kui Li Yue huang Shi-Jie Zheng Li-Ming Song Shuo xiao Qi-Bin Yi Yi Zhao Sheng-Lun Xie Rui Qiao Yan-Qi Du Zhi-Wei Guo Wang-Chen Xue Chao Zheng Jia-Cong Liu Chen-Wei Wang Wen-Jun Tan Yue Wang Jin-Peng Zhang Chao-Yang Li Guo-ying Zhao xiao-Yun Zhao xiao-Lu Zhang Zhen Zhang Wen-Xi Peng Xiang Ma Jing-Yan Shi Dong-Ya Guo Jin Wang Xin-Qiao Li Xiang-Yang Wen Zheng-hua An Fan Zhang College of Physics and Hebei Key Laboratory of Photophysics Research and Application Hebei Normal UniversityShijiazhuang050024China Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing100049China University of Chinese Academy of Sciences Beijing100049China School of Physics and Electronic Science Guizhou Normal UniversityGuiyang550001China Guizhou Provincial Key Laboratory of Radio Astronomy and Data Processing Guizhou Normal UniversityGuiyang550001China School of Physics and Optoelectronics Xiangtan UniversityXiangtan411105China School of Computer and Information Dezhou UniversityDezhou253023China Institute of Astrophysics Central China Normal UniversityWuhan430079China

In the era of time-domain,multi-messenger astronomy,the detection of transient events on the high-energy electromagnetic sky has become more important than *** gravitational wave high-energy electromagnetic counterpart all-sky monitor(GECAM)is a dedicated mission to monitor gamma-ray transients,launched in December,2020.A real-time on-board trigger and location software,using the traditional signal-to-noise ratio(SNR)method for blind search,is constrained to relatively bright signals due to the limitations in on-board computing resources and the need for real-time *** this work,we developed a ground-based pipeline for GECAM to search for various transients,especially for weak bursts missed by on-board *** pipeline includes both automatic and manual mode,offering options for blind search and targeted *** targeted search is specifically designed to search for interesting weak bursts,such as gravitational wave-associated gamma-ray bursts(GRBs).From the ground search of the data in the first year,GECAM has been triggered by 54 GRBs and other transients,including soft gamma-ray repeaters,X-ray binaries,solar flares,terrestrial gamma-ray *** report the properties of each type of triggers,such as trigger time and light *** this search pipeline and assuming a soft Band spectrum,the GRB detection sensitivity of GECAM is increased to about 1.1×10^(-8)erg cm^(-2)s^(-1)(10-1000 ke V,burst duration of 20 s).These results demonstrate that the GECAM ground search system(both blind search and targeted search)is a versatile pipeline to recover true astrophysical signals which were too weak to be found in the on-board search.

关键词： gamma-ray sources gravitational waves data analysis gamma-ray telescopes

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Terahertz transmitter demonstration of the simultaneous transmission of optical and electrical terahertz band signals at 1 Tb/s bit rate and 50 m wireless delivery

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Science China Technological Sciences 2025年第3期68卷 384-386页

作者： Kaihui WANG Jianjun YU Chengzhen BIAN Junjie DING Jiao ZHANG Min ZHU Xiongwei YANG Weiping LI Yi WEI Mingxu WANG Qiutong ZHANG ying wu Bo LIU Wen ZHOU Yuancheng cai Bingchang hua Mingzheng LEI Yucong ZOU Jianguo YU Feng ZHAO State Key Laboratory of ASIC and System Fudan University Purple Mountain Laboratories School of Electronic Engineering Beijing University of Posts and Telecommunications School of Electronic Engineering Xi'an University of Posts and Telecommunications

In recent years, free space optical communication (FSO) has been a hot topic in satellite-to-ground communications, inter-satellite communications,and wireless access networks [1–4]. It has the advantages of rich spectrum resources, no need for spectrum authorization, high spectrum efficiency verified by experiments, narrow beam angle, and low space loss under good weather. In point-to-point communications, the beam angle makes the FSO almost immune to multipath effects, and low-complexity Digital Signal Processing (DSP) algorithms can be used for recovery demodulation.

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Visual outcomes and corneal biomechanical evaluation between LASIK and LASIK combined with accelerated corneal crosslinking

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International Journal of Ophthalmology(English edition) 2025年第3期18卷 496-503页

作者： Li Zhang Yue-hua Zhou xiao-Rui Wang Yan Zheng cai-Yun Fu Xiu-Mei Song Ya-Bin Hu Yue Wang Chang-Bin Zhai Beijing Tongren Eye Center Beijing Tongren Hospital Affiliated to Capital Medical UniversityBeijing Ophthalmology&Visual Science Key LabBeijing 100730China Beijing Ming Vision&Ophthalmology Beijing 100191China College of Ophthalmology Chengdu University of Traditional Chinese MedicineChengdu 610075Sichuan ProvinceChina School of Optometry and Vision Sciences Cardiff UniversityCardiffCF244HQUK

AIM:To assess the visual outcomes and corneal biomechanical properties of myopia patients between laser in situ keratomileusis(LASIK)and LASIK combined with accelerated corneal crosslinking(LASIK Xtra).METHODS:This prospective study analyzed 52 consecutive myopia patients treated with LASIK Xtra and 45 consecutive myopia patients treated with *** the right eyes in the two groups were *** uncorrected distance visual acuity(UDVA),keratometry values,postoperative central corneal thickness(CCT),corneal demarcation line depth,the corneal compensated intraocular pressure(IOPcc),Goldmann-correlated IOP(IOPg),corneal resistance factor(CRF)and corneal hysteresis(CH)from Ocular Response Analyzer(ORA)were ***,the correlation between the demarcation line depth and ORA-related biomechanical parameters were ***:No significant differences in UDVA,postoperative CCT,or mean K values were found between the 2 groups at 1 to 12mo postoperative follow-up(all P>0.05).The changes of CRF was significantly lower in the LASIK Xtra group compared to the LASIK group(all P0.05).Out of 52 cases in the LASIK Xtra group,the demarcation line was present in 40 eyes(77%).The average depth of the demarcation was 220.73±42.70μm(136 to 288μm).No significant correlation was observed between the depth of the demarcation line and any of the ORA-related biomechanical parameters such as IOPcc,IOPg,CRF and CH at 12mo(all P>0.05).CONCLUSION:Both procedures demonstrate comparable outcomes in terms of visual acuity,refraction and ablation *** study confirms that corneal biomechanical properties of the included patients weakened after both procedures,but the cornea after LASIK Xtra are stiffer than conventional LASIK.

关键词： myopia femto-laser in situ keratomileusis laser in situ keratomileusis combined with accelerated corneal crosslinking corneal biomechanics

Research landmarks on the 60th anniversary of Epstein-Barr virus

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Science China(Life Sciences) 2025年第2期68卷 354-380页

作者： Lan-Yi Zhong Chu Xie Le-Le Zhang Yan-Lin Yang Yuan-Tao Liu Ge-Xin Zhao Guo-Long Bu Xian-Shu Tian Zi-ying Jiang Bo-Yu Yuan Peng-Lin Li Pei-huang wu Wei-hua Jia Christian Münz Benjamin E.Gewurz Qian Zhong Cong Sun Mu-Sheng Zeng State Key Laboratory of Oncology in South China Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and TherapyGuangdong Provincial Clinical Research Center for CancerSun Yat-sen University Cancer CenterGuangzhou 510060China Viral Immunobiology Institute of Experimental ImmunologyUniversity of ZürichZürich 8092Switzerland Division of Infectious Diseases Department of MedicineBrigham and Women’s HospitalBoston MA 02115USA Department of Microbiology Harvard Medical SchoolBoston MA 02115USA Harvard Program in Virology Boston MA 02115USA Broad Institute of Harvard and MIT Cambridge MA 02142USA

Epstein-Barr virus(EBV),the first human oncovirus discovered in 1964,has become a focal point in virology,immunology,and oncology because of its unique biological characteristics and significant role in human *** we commemorate the 60th anniversary of EBV's discovery,it is an opportune moment to reflect on the major advancements in our understanding of this complex *** this review,we highlight key milestones in EBV research,including its virion structure and life cycle,interactions with the host immune system,association with EBV-associated diseases,and targeted intervention strategies.

关键词： Epstein-Barr virus oncovirus immune response epidemiology vaccines antibodies